DK4074703T3 - Pyridinyl-(aza)indolsulfonamider - Google Patents
Pyridinyl-(aza)indolsulfonamider Download PDFInfo
- Publication number
- DK4074703T3 DK4074703T3 DK22171413.2T DK22171413T DK4074703T3 DK 4074703 T3 DK4074703 T3 DK 4074703T3 DK 22171413 T DK22171413 T DK 22171413T DK 4074703 T3 DK4074703 T3 DK 4074703T3
- Authority
- DK
- Denmark
- Prior art keywords
- aza
- pyridinyl
- indole sulfonamides
- sulfonamides
- indole
- Prior art date
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N benzopyrrole Natural products C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 title 1
- -1 indole sulfonamides Chemical class 0.000 title 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 title 1
- 229940124530 sulfonamide Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18178429 | 2018-06-19 | ||
| EP19157936 | 2019-02-19 | ||
| EP19733686.0A EP3810591B1 (en) | 2018-06-19 | 2019-06-18 | Pyridinyl and pyrazinyl-(aza)indolsulfonamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK4074703T3 true DK4074703T3 (da) | 2024-01-29 |
Family
ID=67070797
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19733686.0T DK3810591T3 (da) | 2018-06-19 | 2019-06-18 | Pyridinyl- og pyrazinyl-(aza)indolsulfonamider |
| DK22171413.2T DK4074703T3 (da) | 2018-06-19 | 2019-06-18 | Pyridinyl-(aza)indolsulfonamider |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19733686.0T DK3810591T3 (da) | 2018-06-19 | 2019-06-18 | Pyridinyl- og pyrazinyl-(aza)indolsulfonamider |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US11939319B2 (da) |
| EP (2) | EP3810591B1 (da) |
| JP (1) | JP7382973B2 (da) |
| KR (1) | KR20210022675A (da) |
| CN (1) | CN112469710B (da) |
| AU (1) | AU2019289788A1 (da) |
| BR (1) | BR112020025618A2 (da) |
| CA (1) | CA3100795A1 (da) |
| CL (1) | CL2020003202A1 (da) |
| DK (2) | DK3810591T3 (da) |
| ES (2) | ES2972491T3 (da) |
| FI (1) | FI4074703T3 (da) |
| HR (2) | HRP20221290T1 (da) |
| HU (2) | HUE060128T2 (da) |
| IL (1) | IL279428B2 (da) |
| LT (2) | LT3810591T (da) |
| MX (1) | MX2020012173A (da) |
| PL (2) | PL3810591T3 (da) |
| RS (2) | RS63760B1 (da) |
| SG (1) | SG11202012421TA (da) |
| SI (1) | SI4074703T1 (da) |
| TW (1) | TW202016088A (da) |
| UY (1) | UY38266A (da) |
| WO (1) | WO2019243303A1 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113993845A (zh) * | 2019-06-17 | 2022-01-28 | 优时比制药有限公司 | 作为治疗cns障碍例如多发性硬化的gpr17调节剂的n-(苯基)-吲哚-3-磺酰胺衍生物和相关化合物 |
| CN112375027B (zh) * | 2020-12-07 | 2023-03-31 | 中国药科大学 | 吲哚磺酰胺类衍生物及其医药用途 |
| EP4347558A1 (en) * | 2021-06-04 | 2024-04-10 | ReWind Therapeutics NV | 3-pyrrolylsulfonamide compounds as gpr17 antagonists |
| WO2024017858A1 (en) | 2022-07-20 | 2024-01-25 | F. Hoffmann-La Roche Ag | Novel naphthyl and isoquinoline sulfonamide derivatives |
| WO2024017863A1 (en) | 2022-07-20 | 2024-01-25 | F. Hoffmann-La Roche Ag | Novel pyrimidinyl and triazinyl sulfonamide derivatives |
| WO2024017856A1 (en) | 2022-07-20 | 2024-01-25 | F. Hoffmann-La Roche Ag | Novel isoquinolinone, pyrrolopyridinone and thienopyridinone sulfonamide derivatives |
| WO2024017857A1 (en) * | 2022-07-20 | 2024-01-25 | F. Hoffmann-La Roche Ag | Novel imidazopyridine and pyrazolopyridine sulfonamide derivatives |
| WO2024017855A1 (en) * | 2022-07-20 | 2024-01-25 | F. Hoffmann-La Roche Ag | Novel isothiazol-3-yl and isoxazol-3-yl sulfonamide compounds |
| WO2024042147A2 (en) * | 2022-08-26 | 2024-02-29 | F. Hoffmann-La Roche Ag | Novel deuterated pyrimidin-2-yl sulfonamide derivatives |
| WO2024104462A1 (en) * | 2022-11-20 | 2024-05-23 | Myrobalan Therapeutics Nanjing Co. Ltd | Gpr17 modulators and uses thereof |
| WO2024115733A1 (en) * | 2022-12-02 | 2024-06-06 | Rewind Therapeutics Nv | Fused pyrrolyl-sulfonamide compounds |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9702680D0 (sv) | 1997-07-11 | 1997-07-11 | Astra Pharma Prod | New formulation |
| DE19814084B4 (de) | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| SE9904750D0 (sv) | 1999-12-23 | 1999-12-23 | Pharmacia & Upjohn Ab | New formulation, use and method |
| DE602005024537D1 (de) | 2004-04-27 | 2010-12-16 | Takeda Pharmaceutical | Neuer ligand eines g-protein-konjugierten rezeptorproteins und verwendung davon |
| ITMI20042007A1 (it) * | 2004-10-21 | 2005-01-21 | Consiglio Nazionale Ricerche | "modulatori del ricettore gpr17 e loro impieghi terapeutici" |
| AU2006338165B2 (en) | 2005-12-20 | 2010-10-28 | Teikoku Pharma Usa, Inc. | Methods of transdermally administering an indole serotonin receptor agonist and transdermal compositions for use in the same |
| WO2009000262A1 (de) | 2007-06-25 | 2008-12-31 | Acino Ag | Elektrophoretisches transdermales applikationssystem |
| GB2491520A (en) | 2010-03-11 | 2012-12-05 | Jerry Swinford | Method and apparatus for washing downhole tubulars and equipment |
| IT1402549B1 (it) * | 2010-11-03 | 2013-09-13 | Univ Pisa | Composti e composizioni che modulano gpr17 e loro usi terapeutici e diagnostici |
| EP2567698B1 (en) * | 2011-09-07 | 2014-02-12 | Rheinische Friedrich-Wilhelms-Universität Bonn | GPR 17 agonists and screening assay |
| KR20150008468A (ko) | 2012-05-09 | 2015-01-22 | 폰다지오네 이탈리아나 스클레로시 멀티플라 - 에프아이에스엠 온러스 | Gpr17 수용체 조절제 |
| TWI754702B (zh) | 2016-12-28 | 2022-02-11 | 德商Ｕｃｂ製藥有限公司 | （氮雜）吲哚－和苯並呋喃－３－磺醯胺類 |
-
2019
- 2019-05-17 TW TW108117116A patent/TW202016088A/zh unknown
- 2019-06-18 HR HRP20221290TT patent/HRP20221290T1/hr unknown
- 2019-06-18 PL PL19733686.0T patent/PL3810591T3/pl unknown
- 2019-06-18 DK DK19733686.0T patent/DK3810591T3/da active
- 2019-06-18 PL PL22171413.2T patent/PL4074703T3/pl unknown
- 2019-06-18 RS RS20221001A patent/RS63760B1/sr unknown
- 2019-06-18 IL IL279428A patent/IL279428B2/en unknown
- 2019-06-18 MX MX2020012173A patent/MX2020012173A/es unknown
- 2019-06-18 KR KR1020217001631A patent/KR20210022675A/ko active Search and Examination
- 2019-06-18 EP EP19733686.0A patent/EP3810591B1/en active Active
- 2019-06-18 US US17/058,845 patent/US11939319B2/en active Active
- 2019-06-18 FI FIEP22171413.2T patent/FI4074703T3/fi active
- 2019-06-18 CA CA3100795A patent/CA3100795A1/en active Pending
- 2019-06-18 ES ES22171413T patent/ES2972491T3/es active Active
- 2019-06-18 ES ES19733686T patent/ES2929992T3/es active Active
- 2019-06-18 UY UY0001038266A patent/UY38266A/es not_active Application Discontinuation
- 2019-06-18 CN CN201980040596.9A patent/CN112469710B/zh active Active
- 2019-06-18 LT LTEPPCT/EP2019/065967T patent/LT3810591T/lt unknown
- 2019-06-18 AU AU2019289788A patent/AU2019289788A1/en active Pending
- 2019-06-18 EP EP22171413.2A patent/EP4074703B1/en active Active
- 2019-06-18 BR BR112020025618-8A patent/BR112020025618A2/pt unknown
- 2019-06-18 WO PCT/EP2019/065967 patent/WO2019243303A1/en unknown
- 2019-06-18 LT LTEP22171413.2T patent/LT4074703T/lt unknown
- 2019-06-18 SG SG11202012421TA patent/SG11202012421TA/en unknown
- 2019-06-18 RS RS20240230A patent/RS65272B1/sr unknown
- 2019-06-18 HU HUE19733686A patent/HUE060128T2/hu unknown
- 2019-06-18 DK DK22171413.2T patent/DK4074703T3/da active
- 2019-06-18 HU HUE22171413A patent/HUE065411T2/hu unknown
- 2019-06-18 HR HRP20240071TT patent/HRP20240071T1/hr unknown
- 2019-06-18 JP JP2020570915A patent/JP7382973B2/ja active Active
- 2019-06-18 SI SI201930697T patent/SI4074703T1/sl unknown
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2020
- 2020-12-10 CL CL2020003202A patent/CL2020003202A1/es unknown
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