DK39985D0 - Fremgangsmaade til radioaktiv maerkning af diagnostiske og terapeutiske midler indeholdende et cheleringsmiddel - Google Patents
Fremgangsmaade til radioaktiv maerkning af diagnostiske og terapeutiske midler indeholdende et cheleringsmiddelInfo
- Publication number
- DK39985D0 DK39985D0 DK39985A DK39985A DK39985D0 DK 39985 D0 DK39985 D0 DK 39985D0 DK 39985 A DK39985 A DK 39985A DK 39985 A DK39985 A DK 39985A DK 39985 D0 DK39985 D0 DK 39985D0
- Authority
- DK
- Denmark
- Prior art keywords
- radioactive metal
- binding affinity
- metal ion
- diagnostic agent
- diagnostic
- Prior art date
Links
- 239000000032 diagnostic agent Substances 0.000 title abstract 5
- 229940039227 diagnostic agent Drugs 0.000 title abstract 5
- 239000003814 drug Substances 0.000 title abstract 5
- 229940124597 therapeutic agent Drugs 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 239000003795 chemical substances by application Substances 0.000 title 1
- 238000000163 radioactive labelling Methods 0.000 title 1
- 230000002285 radioactive effect Effects 0.000 abstract 6
- 229910021645 metal ion Inorganic materials 0.000 abstract 5
- 230000001225 therapeutic effect Effects 0.000 abstract 4
- 239000000463 material Substances 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- 229910052755 nonmetal Inorganic materials 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/534—Production of labelled immunochemicals with radioactive label
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/804—Radioisotope, e.g. radioimmunoassay
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/575,397 US4707352A (en) | 1984-01-30 | 1984-01-30 | Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group |
Publications (2)
Publication Number | Publication Date |
---|---|
DK39985D0 true DK39985D0 (da) | 1985-01-29 |
DK39985A DK39985A (da) | 1985-07-31 |
Family
ID=24300158
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK39985A DK39985A (da) | 1984-01-30 | 1985-01-29 | Fremgangsmaade til radioaktiv maerkning af diagnostiske og terapeutiske midler indeholdende et cheleringsmiddel |
Country Status (11)
Country | Link |
---|---|
US (3) | US4707352A (da) |
EP (1) | EP0150844B1 (da) |
JP (1) | JPH0822822B2 (da) |
AT (1) | ATE92190T1 (da) |
AU (1) | AU597208B2 (da) |
CA (1) | CA1256023A (da) |
DE (1) | DE3587477T2 (da) |
DK (1) | DK39985A (da) |
ES (1) | ES8704001A1 (da) |
IL (1) | IL74187A (da) |
NO (1) | NO850353L (da) |
Families Citing this family (91)
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US5001072A (en) * | 1984-05-23 | 1991-03-19 | Icn Biomedicals Inc. | Compositions and methods for multiple simultaneous immunoradiometric assay (IRMA) of analytes using radioisotope chelate labels |
US4898724A (en) * | 1984-06-04 | 1990-02-06 | The Dow Chemical Company | Organis amine phosphonic acid complexes for the treatment of calcific tumors |
US5221605A (en) * | 1984-10-31 | 1993-06-22 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
US5238808A (en) * | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
US5310687A (en) * | 1984-10-31 | 1994-05-10 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
US4707544A (en) * | 1984-11-28 | 1987-11-17 | President And Fellows Of Harvard College | Metal-isonitrile adducts for preparing radionuclide complexes for labelling and imaging agents |
US4894445A (en) * | 1985-08-05 | 1990-01-16 | E. I. Du Pont De Nemours And Company | Metal-isonitrile adducts for preparing radionuclide complexes |
CA1293729C (en) * | 1985-08-05 | 1991-12-31 | Alan Purdom Carpenter Jr | Metal-isonitrile adducts for preparing radionuclide complexes |
US5155216A (en) * | 1985-08-15 | 1992-10-13 | Amoco Corporation | Nucleic acids labeled with a chemiluminescent acridine ester |
US5336762A (en) * | 1985-11-18 | 1994-08-09 | Access Pharmaceuticals, Inc. | Polychelating agents for image and spectral enhancement (and spectral shift) |
JP3293820B2 (ja) * | 1985-12-13 | 2002-06-17 | エンゾ− バイオケム インコ−ポレイテツド | 標的ポリヌクレオチドにハイブリツド形成するための新規な一工程方法とポリヌクレオチド化合物 |
US4831122A (en) * | 1986-01-09 | 1989-05-16 | Regents Of The University Of Minnesota | Radioimmunotoxins |
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US5011959A (en) * | 1986-11-17 | 1991-04-30 | The Board Of Regents, The University Of Texas System | 1,2-diaminocyclohexane-platinum complexes with antitumor activity |
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WO1989005853A1 (en) * | 1987-12-15 | 1989-06-29 | Synthetic Genetics | Nucleic acid chelate conjugate as therapeutic and diagnostic agents |
DE58906384D1 (de) * | 1988-01-20 | 1994-01-27 | Ciba Geigy | Verfahren zur Herstellung von Komplexverbindungen. |
US6326136B1 (en) | 1988-04-01 | 2001-12-04 | Digene Corporation | Macromolecular conjugate made using unsaturated aldehydes |
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EP0339389B1 (de) * | 1988-04-25 | 1993-09-22 | F. Hoffmann-La Roche Ag | Diagnose-Hilfsmittel |
US5059541A (en) * | 1988-04-29 | 1991-10-22 | Neorx Corporation | Minimal derivatization of proteins |
US4917878A (en) * | 1988-05-02 | 1990-04-17 | Thomas Jefferson University | Novel use of a radiolabelled antibody against stage specific embryonic antigen for the detection of occult abscesses in mammals |
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US5393909A (en) * | 1988-11-22 | 1995-02-28 | Board Of Regents, The University Of Texas System | Diamine platinum complexes as antitumor agents |
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Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3936440A (en) * | 1974-05-22 | 1976-02-03 | Drexel University | Method of labeling complex metal chelates with radioactive metal isotopes |
FR2281134A1 (fr) * | 1974-08-06 | 1976-03-05 | Commissariat Energie Atomique | Procede de marquage au 99m technetium |
US4043998A (en) * | 1974-10-09 | 1977-08-23 | The Board Of Trustees Of The Leland Stanford Junior University | 1-(P-benzenediazonium)-ethylenediamine tetraacetic acid |
US4272503A (en) * | 1978-05-25 | 1981-06-09 | New England Nuclear Corporation | Reductant composition for technetium-99m and method for making technetium-99m labelled ligands |
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US4320109A (en) * | 1979-06-29 | 1982-03-16 | The University Of Southern California | Immunoradiometric assay employing terminal radionuclide labeling and synthesis of conjugates for such assay |
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CA1222691A (en) * | 1981-12-29 | 1987-06-09 | Wilhelmus T. Goedemans | Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments |
GB2122641B (en) * | 1982-06-07 | 1986-08-06 | Otto A Gansow | Metal chelate conjugated monoclonal antibodies where in the metal is an emitter |
US4479930A (en) * | 1982-07-26 | 1984-10-30 | Trustees Of The University Of Massachusetts | Amines coupled wth dicyclic dianhydrides capable of being radiolabeled product |
US4652519A (en) * | 1983-02-03 | 1987-03-24 | Yeda Research And Development Company Limited | Bifunctional chelating agents and process for their production |
JPS59199636A (ja) * | 1983-04-26 | 1984-11-12 | Nippon Mejifuijitsukusu Kk | 放射性診断剤 |
US4732864A (en) * | 1983-10-06 | 1988-03-22 | E. I. Du Pont De Nemours And Company | Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules |
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-
1984
- 1984-01-30 US US06/575,397 patent/US4707352A/en not_active Expired - Lifetime
-
1985
- 1985-01-25 CA CA000472895A patent/CA1256023A/en not_active Expired
- 1985-01-29 EP EP85100899A patent/EP0150844B1/en not_active Expired - Lifetime
- 1985-01-29 NO NO850353A patent/NO850353L/no unknown
- 1985-01-29 DE DE85100899T patent/DE3587477T2/de not_active Expired - Lifetime
- 1985-01-29 AT AT85100899T patent/ATE92190T1/de not_active IP Right Cessation
- 1985-01-29 IL IL74187A patent/IL74187A/xx unknown
- 1985-01-29 DK DK39985A patent/DK39985A/da not_active Application Discontinuation
- 1985-01-29 ES ES539927A patent/ES8704001A1/es not_active Expired
- 1985-01-30 JP JP60014635A patent/JPH0822822B2/ja not_active Expired - Lifetime
- 1985-01-30 AU AU38213/85A patent/AU597208B2/en not_active Ceased
-
1987
- 1987-01-23 US US07/006,819 patent/US4772548A/en not_active Expired - Lifetime
- 1987-01-23 US US07/006,818 patent/US4767609A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK39985A (da) | 1985-07-31 |
DE3587477D1 (de) | 1993-09-02 |
IL74187A (en) | 1989-03-31 |
IL74187A0 (en) | 1985-04-30 |
US4707352A (en) | 1987-11-17 |
DE3587477T2 (de) | 1994-02-17 |
AU3821385A (en) | 1985-08-08 |
AU597208B2 (en) | 1990-05-24 |
US4772548A (en) | 1988-09-20 |
JPS60178827A (ja) | 1985-09-12 |
EP0150844B1 (en) | 1993-07-28 |
EP0150844A3 (en) | 1988-05-04 |
US4767609A (en) | 1988-08-30 |
JPH0822822B2 (ja) | 1996-03-06 |
EP0150844A2 (en) | 1985-08-07 |
NO850353L (no) | 1985-07-31 |
ES8704001A1 (es) | 1987-03-01 |
ES539927A0 (es) | 1987-03-01 |
CA1256023A (en) | 1989-06-20 |
ATE92190T1 (de) | 1993-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |