DE69423753T2 - Polyoximverbindungen und deren herstellung - Google Patents
Polyoximverbindungen und deren herstellungInfo
- Publication number
- DE69423753T2 DE69423753T2 DE69423753T DE69423753T DE69423753T2 DE 69423753 T2 DE69423753 T2 DE 69423753T2 DE 69423753 T DE69423753 T DE 69423753T DE 69423753 T DE69423753 T DE 69423753T DE 69423753 T2 DE69423753 T2 DE 69423753T2
- Authority
- DE
- Germany
- Prior art keywords
- baseplate
- polyoxime
- production
- organic molecules
- organic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5759493A | 1993-05-05 | 1993-05-05 | |
US08/105,904 US6001364A (en) | 1993-05-05 | 1993-08-31 | Hetero-polyoxime compounds and their preparation by parallel assembly |
US08/114,877 US6174530B1 (en) | 1993-05-05 | 1993-08-31 | Homogeneous polyoxime compositions and their preparation by parallel assembly |
PCT/IB1994/000093 WO1994025071A1 (en) | 1993-05-05 | 1994-05-05 | Polyoxime compounds and their preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69423753D1 DE69423753D1 (de) | 2000-05-04 |
DE69423753T2 true DE69423753T2 (de) | 2000-11-02 |
Family
ID=27369284
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69423753T Expired - Fee Related DE69423753T2 (de) | 1993-05-05 | 1994-05-05 | Polyoximverbindungen und deren herstellung |
Country Status (11)
Country | Link |
---|---|
US (1) | US6663869B1 (de) |
EP (1) | EP0697891B1 (de) |
JP (1) | JP3734828B2 (de) |
AT (1) | ATE191148T1 (de) |
AU (1) | AU686153B2 (de) |
CA (1) | CA2162157A1 (de) |
DE (1) | DE69423753T2 (de) |
DK (1) | DK0697891T3 (de) |
ES (1) | ES2146649T3 (de) |
GR (1) | GR3033699T3 (de) |
PT (1) | PT697891E (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007524584A (ja) * | 2003-05-09 | 2007-08-30 | ノボ ノルディスク アクティーゼルスカブ | 肥満の治療に使用するペプチド |
MXPA05011830A (es) * | 2003-05-09 | 2006-01-26 | Novo Nordisk As | Peptidos para uso en el tratamiento de la obesidad. |
US20090203581A1 (en) * | 2005-07-18 | 2009-08-13 | Novo Nordisk A/S | Novel Peptides for Use in the Treatment of Obesity |
WO2008013735A2 (en) * | 2006-07-21 | 2008-01-31 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Methods for conjugation of oligosaccharides or polysaccharides to protein carriers through oxime linkages via 3-deoxy-d-manno-octulsonic acid |
JP2010516652A (ja) * | 2007-01-18 | 2010-05-20 | ノボ・ノルデイスク・エー/エス | 肥満の治療に使用される新規ペプチド |
US20100016238A1 (en) * | 2007-01-18 | 2010-01-21 | Novo Nordisk A/S | Peptides for Use in the Treatment of Obesity |
US20100022446A1 (en) * | 2007-01-18 | 2010-01-28 | Novo Nordisk A/S | Use of Peptides in Combination with Surgical Intervention for the Treatment of Obesity |
NZ602170A (en) | 2008-02-08 | 2014-03-28 | Ambrx Inc | Modified leptin polypeptides and their uses |
WO2010060901A1 (en) * | 2008-11-25 | 2010-06-03 | Novo Nordisk A/S | Peptides for treatment of obesity |
US8647621B2 (en) | 2009-07-27 | 2014-02-11 | Fina Biosolutions, Llc | Method of producing protein-carbohydrate vaccines reduced in free carbohydrate |
JP6564539B1 (ja) | 2018-09-14 | 2019-08-21 | 長瀬産業株式会社 | スルホン酸化合物によるペプチド精製方法 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4444744A (en) | 1980-03-03 | 1984-04-24 | Goldenberg Milton David | Tumor localization and therapy with labeled antibodies to cell surface antigens |
US4622420A (en) | 1980-03-18 | 1986-11-11 | The Regents Of The University Of California | Chelating agents and method |
US4865835A (en) | 1982-06-02 | 1989-09-12 | Begent Richard H J | Diagnosis and treatment of tumors |
US4507466A (en) | 1983-01-07 | 1985-03-26 | The Dow Chemical Corporation | Dense star polymers having core, core branches, terminal groups |
JPS59215321A (ja) | 1983-05-23 | 1984-12-05 | Sumitomo Chem Co Ltd | 二官能性配位子化合物を結合した反応性高分子 |
US4707352A (en) | 1984-01-30 | 1987-11-17 | Enzo Biochem, Inc. | Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group |
US4652440A (en) | 1984-05-03 | 1987-03-24 | Paik Chang H | Method of stably radiolabeling antibodies with technetium and rhenium |
IL71947A (en) | 1984-05-29 | 1987-10-30 | Yeda Research And Dev Comp Ltd | Enzyme hydrazides and method for detection and determination of glycoconjugates |
US4659839A (en) | 1984-10-10 | 1987-04-21 | Mallinckrodt, Inc. | Coupling agents for radiolabeled antibody fragments |
US4918164A (en) | 1987-09-10 | 1990-04-17 | Oncogen | Tumor immunotherapy using anti-idiotypic antibodies |
US4678667A (en) | 1985-07-02 | 1987-07-07 | 501 Regents of the University of California | Macrocyclic bifunctional chelating agents |
GB8610551D0 (en) | 1986-04-30 | 1986-06-04 | Hoffmann La Roche | Polypeptide & protein derivatives |
IN165717B (de) | 1986-08-07 | 1989-12-23 | Battelle Memorial Institute | |
JPH0611290B2 (ja) | 1986-11-05 | 1994-02-16 | 住友ベークライト株式会社 | ポリビニルアルコ−ルゲルのγ線滅菌法 |
US4861581A (en) | 1986-12-05 | 1989-08-29 | Cancer Biologics, Inc. | Detection of necrotic malignant tissue and associated therapy |
US5084266A (en) | 1988-02-03 | 1992-01-28 | The University Of Melbourne | Method for tumor imaging utilizing a labelled tumor specific antibody and a non-tumor reactive antibody |
US4857599A (en) | 1988-02-08 | 1989-08-15 | The Dow Chemical Company | Modified dense star polymers |
GB8820377D0 (en) | 1988-08-26 | 1988-09-28 | Offord R E | Chemical compounds |
GB9004538D0 (en) * | 1990-02-28 | 1990-04-25 | Offord Robin E | Chemical compounds |
US5011676A (en) | 1990-03-27 | 1991-04-30 | Thomas Jefferson University | Method to directly radiolabel antibodies for diagnostic imaging and therapy |
ATE152917T1 (de) * | 1990-09-28 | 1997-05-15 | Neorx Corp | Polymere träger zur freisetzung kovalent gebundener wirkstoffe |
GB9102450D0 (en) | 1991-02-05 | 1991-03-20 | Sandoz Ltd | Improvements in or relating to organic compounds |
US5272253A (en) * | 1991-07-01 | 1993-12-21 | Eli Lilly And Company | Cluster conjugates of drugs with antibodies |
WO1994025071A1 (en) | 1993-05-05 | 1994-11-10 | Keith Rose | Polyoxime compounds and their preparation |
US6174530B1 (en) * | 1993-05-05 | 2001-01-16 | Gryphon Sciences | Homogeneous polyoxime compositions and their preparation by parallel assembly |
US6001364A (en) * | 1993-05-05 | 1999-12-14 | Gryphon Sciences | Hetero-polyoxime compounds and their preparation by parallel assembly |
-
1994
- 1994-05-05 AU AU65438/94A patent/AU686153B2/en not_active Ceased
- 1994-05-05 CA CA002162157A patent/CA2162157A1/en not_active Abandoned
- 1994-05-05 JP JP52408094A patent/JP3734828B2/ja not_active Expired - Fee Related
- 1994-05-05 AT AT94913192T patent/ATE191148T1/de not_active IP Right Cessation
- 1994-05-05 ES ES94913192T patent/ES2146649T3/es not_active Expired - Lifetime
- 1994-05-05 DE DE69423753T patent/DE69423753T2/de not_active Expired - Fee Related
- 1994-05-05 EP EP94913192A patent/EP0697891B1/de not_active Expired - Lifetime
- 1994-05-05 PT PT94913192T patent/PT697891E/pt unknown
- 1994-05-05 DK DK94913192T patent/DK0697891T3/da active
-
2000
- 2000-06-15 GR GR20000401389T patent/GR3033699T3/el not_active IP Right Cessation
- 2000-08-04 US US09/633,269 patent/US6663869B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH08510210A (ja) | 1996-10-29 |
CA2162157A1 (en) | 1994-11-10 |
ES2146649T3 (es) | 2000-08-16 |
AU6543894A (en) | 1994-11-21 |
JP3734828B2 (ja) | 2006-01-11 |
EP0697891B1 (de) | 2000-03-29 |
GR3033699T3 (en) | 2000-10-31 |
DK0697891T3 (da) | 2000-09-04 |
PT697891E (pt) | 2000-09-29 |
AU686153B2 (en) | 1998-02-05 |
US6663869B1 (en) | 2003-12-16 |
ATE191148T1 (de) | 2000-04-15 |
DE69423753D1 (de) | 2000-05-04 |
EP0697891A1 (de) | 1996-02-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69423753D1 (de) | Polyoximverbindungen und deren herstellung | |
ES2141610T3 (es) | Compuestos con atomos espiranicos y su uso como materiales electroluminiscentes. | |
BR8504463A (pt) | Resina quimicamente endurecivel,processo para sua preparacao,misturas de compostos e misturas endurecidas de compostos | |
DK392084D0 (da) | Haerdelige materialer | |
PT98169A (pt) | Processo para a preparacao de analogos de oligonucleotidos com ligacoes internucleotido 3'-3' ou 5'-5' terminais | |
DE59303552D1 (de) | Modifiziertes Chlorhexidin-Addukt | |
KR960007722A (ko) | 전도성 측쇄형 액정화합물 및 이를 사용한 배향막 | |
DE69213227D1 (de) | Herstellung von zementmörteltrockenmischung | |
BR9405608A (pt) | Processo para preparaçào de polìmeros contendo lignina | |
CA2032669A1 (en) | Process for incorporating o-hydroxyphenyl-s-triazines in organic polymers | |
AU583624B2 (en) | Polymers with pendant isocyanatocarbonyl groups, and their production processes, and compositions comprising them | |
WO1993015203A3 (en) | Polypeptides with fibronectin binding sites as modulators for matrix assembly | |
CA2033444A1 (en) | Production of elastic, compact or cellular moldings based on elastomers containing n-benzylurea groups in bound form, elastomers of this type, and n-benzylpolyoxyalkylene-polyamines which are suitable for this purpose | |
BR9810210A (pt) | Melhoramentos em ou referentes a composiçõespoliméricas | |
MY111987A (en) | Heat resistant resin composition, heat resistant film adhesive and process for producing the same | |
ES2103194B1 (es) | Colorantes reactivos de aluminio-ftalocianina. | |
KR910004748A (ko) | 경화형 조성물 | |
ATE178346T1 (de) | Verbesserte zusammensetzungen von bitumen, ihren verfahren zur herstellung und ihre anwendungen | |
MX9408333A (es) | Colorantes de dizaso de la serie estilbeno y procedimiento para su produccion. | |
ATE71103T1 (de) | Organische phosphor-macroringe, verfahren zu ihrer herstellung und ihre verwendungen. | |
DE68921648D1 (de) | Supraleiter und Verfahren zu deren Herstellung. | |
JPS6420226A (en) | Production of modified epoxy resin | |
KR890011600A (ko) | 세포증식 억제성 안트라사이클린 항생제의 안정화된 건식 제제 및 이의 제조방법 | |
TWI255831B (en) | Heat resistant molded article | |
KR900014467A (ko) | 폴리아미드수지와 그의 제조방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |