DK3814533T3 - Mikro-RNA-signaturer til forudsigelse af leverdysfunktion - Google Patents

Mikro-RNA-signaturer til forudsigelse af leverdysfunktion Download PDF

Info

Publication number
DK3814533T3
DK3814533T3 DK19773418.9T DK19773418T DK3814533T3 DK 3814533 T3 DK3814533 T3 DK 3814533T3 DK 19773418 T DK19773418 T DK 19773418T DK 3814533 T3 DK3814533 T3 DK 3814533T3
Authority
DK
Denmark
Prior art keywords
micro
liver dysfunction
rna signatures
predict liver
predict
Prior art date
Application number
DK19773418.9T
Other languages
English (en)
Inventor
Matthias Hackl
Alice Assinger
Patrick Starlinger
Original Assignee
Tamirna Gmbh
Univ Wien Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tamirna Gmbh, Univ Wien Med filed Critical Tamirna Gmbh
Application granted granted Critical
Publication of DK3814533T3 publication Critical patent/DK3814533T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK19773418.9T 2018-09-20 2019-09-20 Mikro-RNA-signaturer til forudsigelse af leverdysfunktion DK3814533T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT508042018 2018-09-20
PCT/EP2019/075319 WO2020058472A1 (en) 2018-09-20 2019-09-20 Micro-rna signatures for the prediction of liver dysfunction

Publications (1)

Publication Number Publication Date
DK3814533T3 true DK3814533T3 (da) 2021-11-15

Family

ID=68051797

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19773418.9T DK3814533T3 (da) 2018-09-20 2019-09-20 Mikro-RNA-signaturer til forudsigelse af leverdysfunktion

Country Status (10)

Country Link
US (1) US11339440B2 (da)
EP (1) EP3814533B1 (da)
JP (1) JP7045527B2 (da)
KR (1) KR102339206B1 (da)
CA (1) CA3110668C (da)
DK (1) DK3814533T3 (da)
ES (1) ES2899203T3 (da)
PL (1) PL3814533T3 (da)
SG (1) SG11202101798QA (da)
WO (1) WO2020058472A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111363829B (zh) * 2020-05-27 2020-09-22 北京信诺卫康科技有限公司 胆管癌的miRNA标记物及其应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3102800B2 (ja) 1994-08-19 2000-10-23 パーキン−エルマー コーポレイション 増幅及び連結反応の共役法
GB9626815D0 (en) 1996-12-23 1997-02-12 Cemu Bioteknik Ab Method of sequencing DNA
US6969488B2 (en) 1998-05-22 2005-11-29 Solexa, Inc. System and apparatus for sequential processing of analytes
AR021833A1 (es) 1998-09-30 2002-08-07 Applied Research Systems Metodos de amplificacion y secuenciacion de acido nucleico
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
US7501245B2 (en) 1999-06-28 2009-03-10 Helicos Biosciences Corp. Methods and apparatuses for analyzing polynucleotide sequences
WO2001023610A2 (en) 1999-09-29 2001-04-05 Solexa Ltd. Polynucleotide sequencing
DE60131194T2 (de) 2000-07-07 2008-08-07 Visigen Biotechnologies, Inc., Bellaire Sequenzbestimmung in echtzeit
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
AU2005296200B2 (en) 2004-09-17 2011-07-14 Pacific Biosciences Of California, Inc. Apparatus and method for analysis of molecules
US7170050B2 (en) 2004-09-17 2007-01-30 Pacific Biosciences Of California, Inc. Apparatus and methods for optical analysis of molecules
US7482120B2 (en) 2005-01-28 2009-01-27 Helicos Biosciences Corporation Methods and compositions for improving fidelity in a nucleic acid synthesis reaction
US7282337B1 (en) 2006-04-14 2007-10-16 Helicos Biosciences Corporation Methods for increasing accuracy of nucleic acid sequencing
CN101418343A (zh) 2008-12-10 2009-04-29 复旦大学附属中山医院 miRNA在预测早期原发性肝癌病人术后复发的应用及其试剂盒
EP2196543A1 (en) 2008-12-15 2010-06-16 Koninklijke Philips Electronics N.V. Compositions and methods for micro-rna expression profiling of hepatocellular cancer
US20120183116A1 (en) 2009-07-30 2012-07-19 Hollenbach Daniel F Composite nuclear fuel pellet
WO2011076141A1 (en) 2009-12-24 2011-06-30 Fudan University Diagnostic kits comprising microrna biomarkers and methods for diagnosis of hepatocellular cancer
EP2566985A4 (en) 2010-05-06 2014-08-06 Ibis Biosciences Inc INTEGRATED SAMPLE PREPARATION SYSTEMS AND MIXTURES OF STABILIZED ENZYMES
WO2012151212A1 (en) 2011-05-01 2012-11-08 University Of Rochester Multifocal hepatocellular carcinoma microrna expression patterns and uses thereof
CN102776185B (zh) 2011-05-06 2013-07-10 复旦大学附属中山医院 由血浆microRNA组合成的肝癌诊断标志物及一种诊断肝癌的新方法
WO2012151736A1 (en) 2011-05-06 2012-11-15 Zhongshan Hospital Fudan University Marker consisting of plasma microrna and new method for diagnosis of hepatocellular carcinoma
US10155941B2 (en) 2012-08-01 2018-12-18 Bernhard Suter High throughput yeast two-hybrid screening method and reagent kit
EP2829613A1 (en) * 2013-07-26 2015-01-28 Istituto Nazionale Di Genetica Molecolare-INGM Biomarkers of liver diseases and uses thereof
JP6837838B2 (ja) 2014-06-18 2021-03-03 東レ株式会社 肝臓がんの検出キット又はデバイス及び検出方法
US10801072B2 (en) 2014-09-04 2020-10-13 Miodx Method of analysis allowing avoidance of surgery
WO2016049512A1 (en) 2014-09-26 2016-03-31 University Of Massachusetts Rna-modulating agents
WO2018231851A1 (en) 2017-06-13 2018-12-20 Gilead Sciences, Inc. Methods of treating liver fibrosis

Also Published As

Publication number Publication date
EP3814533B1 (en) 2021-08-11
JP2021527448A (ja) 2021-10-14
KR102339206B1 (ko) 2021-12-14
CN112867802A (zh) 2021-05-28
US11339440B2 (en) 2022-05-24
CA3110668C (en) 2022-01-11
ES2899203T3 (es) 2022-03-10
KR20210057065A (ko) 2021-05-20
PL3814533T3 (pl) 2022-01-31
US20210269882A1 (en) 2021-09-02
JP7045527B2 (ja) 2022-03-31
EP3814533A1 (en) 2021-05-05
SG11202101798QA (en) 2021-04-29
CA3110668A1 (en) 2020-03-26
WO2020058472A1 (en) 2020-03-26

Similar Documents

Publication Publication Date Title
DK3512850T3 (da) Inhibitorer af menin-mll-interaktionen
DK3468966T3 (da) Inhibitorer af menin-mll-interaktionen
DK3244891T3 (da) Forbindelser til forbedring af mrna-splejsning
DK3471749T3 (da) Fremgangsmåder og sammensætninger til detektering af en mål-RNA
DK3316703T3 (da) Fremgangsmåde til forbedring af dyrs ydeevne
DK3423451T3 (da) Inhibitorer af wdr5-protein-proteinbinding
DK3497207T3 (da) Fremgangsmåder til påvisning af aav
DK3757214T3 (da) Sammensætninger til modulering af sod-1-ekspression
DK3237707T3 (da) Modulært anlæg samt monteringssæt til opsætning af et modulært anlæg
DK3319967T3 (da) Forbindelser til inhibering af notch-signalvejen
DK3460141T3 (da) System til opretning af gelænderplader
DK3523315T3 (da) Inhibitor af glucocorticoidreceptor
DK3534709T3 (da) Substituerede sulfonylamider til bekæmpelse af skadedyr
DK3177931T3 (da) Fremgangsmåde til bestemmelse af stoffers evne til at binde til analytaktive steder
DK3286075T3 (da) Fremgangsmåde til at styre brændstofforbruget af et skib
DK3510065T3 (da) Egenskabsforbedring af pmma-skum ved anvendelse af methacrylamider
DK4064706T3 (da) Signalering af information relateret til blændevinkel
DK3591122T3 (da) Hurtigskifter
DK3678648T3 (da) Fremgangsmåder til anvendelse af dipivefrin
DK3525807T3 (da) Hæmmer af rna-polymerase ii
DK3827036T3 (da) Sammensætning til strukturklæbstof
DK3430004T3 (da) Faststofformer af nilotinibsalte
DK3458797T3 (da) Magasin til affyring af modforanstaltninger
DK3417683T3 (da) Bæremontering til bæring af et elektronisk hylster
DK3746353T3 (da) Forbedringer af drivenheder til anhængere