DK377984A - Azulenderivater, fremgangsmaader til deres syntese og deres anvendelsersom anti-ulcerative og anti-inflammatoriske midler - Google Patents
Azulenderivater, fremgangsmaader til deres syntese og deres anvendelsersom anti-ulcerative og anti-inflammatoriske midler Download PDFInfo
- Publication number
- DK377984A DK377984A DK377984A DK377984A DK377984A DK 377984 A DK377984 A DK 377984A DK 377984 A DK377984 A DK 377984A DK 377984 A DK377984 A DK 377984A DK 377984 A DK377984 A DK 377984A
- Authority
- DK
- Denmark
- Prior art keywords
- azulender
- ulcerative
- procedures
- synthesis
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/47—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having at least one of the sulfo groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15318783 | 1983-08-24 | ||
| JP15318783A JPS6048960A (ja) | 1983-08-24 | 1983-08-24 | アズレン誘導体及びその製法並びにこの化合物を有効成分とする抗潰瘍剤 |
| JP1402884 | 1984-01-28 | ||
| JP1402884A JPS60158160A (ja) | 1984-01-28 | 1984-01-28 | アズレン誘導体スルホン酸塩、抗潰瘍、抗炎症剤及びその製法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK377984D0 DK377984D0 (da) | 1984-08-03 |
| DK377984A true DK377984A (da) | 1985-02-25 |
| DK169870B1 DK169870B1 (da) | 1995-03-20 |
Family
ID=26349908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK377984A DK169870B1 (da) | 1983-08-24 | 1984-08-03 | Azulenderivater, fremgangsmåde til deres syntese og anti-ulcerative og anti-inflammatoriske midler omfattende disse derivater |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4595694A (da) |
| EP (1) | EP0147915B1 (da) |
| KR (1) | KR920000956B1 (da) |
| AR (1) | AR240554A1 (da) |
| AU (1) | AU571554B2 (da) |
| CA (1) | CA1228862A (da) |
| DE (1) | DE3463502D1 (da) |
| DK (1) | DK169870B1 (da) |
| ES (1) | ES535381A0 (da) |
| HU (1) | HU195478B (da) |
| NO (1) | NO158673C (da) |
| PT (1) | PT79119B (da) |
| SU (1) | SU1311618A3 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5081152A (en) * | 1989-07-05 | 1992-01-14 | Kotobuki Seiyaku Co., Ltd. | Azulene derivatives as thromboxane a2 and prostaglandin endoperoxide receptor antagonist |
| EP0887077A1 (de) * | 1997-06-27 | 1998-12-30 | Roche Diagnostics GmbH | Verwendung von Azulenderivaten als Metalloproteaseinhibitoren |
| US6420435B1 (en) | 1999-11-01 | 2002-07-16 | Joe S. Wilkins, Jr. | Method for treating gastrointestinal disorders |
| DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
| US7041706B2 (en) * | 2002-04-19 | 2006-05-09 | Wilkins Jr Joe S | Method for treating crohn's disease |
| EP2392258B1 (en) | 2005-04-28 | 2014-10-08 | Proteus Digital Health, Inc. | Pharma-informatics system |
| US8795627B2 (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates |
| AU2010216512B2 (en) | 2009-02-20 | 2016-06-30 | 2-Bbb Medicines B.V. | Glutathione-based drug delivery system |
| WO2010129819A2 (en) | 2009-05-06 | 2010-11-11 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1227896B (de) * | 1965-12-02 | 1966-11-03 | Degussa | Verfahren zur Herstellung wasserloeslicher stabiler Salze von Azulensulfonsaeureamiden |
| US3816612A (en) * | 1967-03-23 | 1974-06-11 | Degussa | Process for the production of basically reacting pharmaceuticals |
| US3974299A (en) * | 1974-07-08 | 1976-08-10 | Dynapol | Ionic sweetener |
| US4283347A (en) * | 1979-04-13 | 1981-08-11 | Scm Corporation | Para-menth-1-ene-7-sulfonic acid and salts thereof |
| US4224240A (en) * | 1979-04-13 | 1980-09-23 | Scm Corporation | Preparation of para-menth-1-ene-7-sulfonate salts and corresponding acids |
-
1984
- 1984-08-01 AU AU31396/84A patent/AU571554B2/en not_active Expired
- 1984-08-03 DK DK377984A patent/DK169870B1/da not_active IP Right Cessation
- 1984-08-15 CA CA000461108A patent/CA1228862A/en not_active Expired
- 1984-08-17 US US06/642,043 patent/US4595694A/en not_active Expired - Lifetime
- 1984-08-23 SU SU3785251A patent/SU1311618A3/ru active
- 1984-08-23 KR KR1019840005107A patent/KR920000956B1/ko not_active IP Right Cessation
- 1984-08-23 DE DE8484305775T patent/DE3463502D1/de not_active Expired
- 1984-08-23 EP EP84305775A patent/EP0147915B1/en not_active Expired
- 1984-08-23 ES ES535381A patent/ES535381A0/es active Granted
- 1984-08-23 PT PT79119A patent/PT79119B/pt unknown
- 1984-08-23 NO NO843377A patent/NO158673C/no unknown
- 1984-08-23 AR AR29767884A patent/AR240554A1/es active
- 1984-08-23 HU HU843172A patent/HU195478B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR920000956B1 (ko) | 1992-01-31 |
| DE3463502D1 (en) | 1987-06-11 |
| PT79119B (en) | 1986-07-17 |
| US4595694A (en) | 1986-06-17 |
| HU195478B (en) | 1988-05-30 |
| ES8506607A1 (es) | 1985-07-16 |
| DK169870B1 (da) | 1995-03-20 |
| NO158673B (no) | 1988-07-11 |
| HUT37393A (en) | 1985-12-28 |
| NO843377L (no) | 1985-02-25 |
| AU3139684A (en) | 1985-02-28 |
| PT79119A (en) | 1984-09-01 |
| CA1228862A (en) | 1987-11-03 |
| SU1311618A3 (ru) | 1987-05-15 |
| ES535381A0 (es) | 1985-07-16 |
| NO158673C (no) | 1988-10-19 |
| DK377984D0 (da) | 1984-08-03 |
| EP0147915A1 (en) | 1985-07-10 |
| EP0147915B1 (en) | 1987-05-06 |
| AU571554B2 (en) | 1988-04-21 |
| KR850001731A (ko) | 1985-04-01 |
| AR240554A1 (es) | 1990-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |
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