DK376986A - Di-tert-butylphenol-forbindelser og fremgangsmaade til fremstilling heraf - Google Patents

Di-tert-butylphenol-forbindelser og fremgangsmaade til fremstilling heraf Download PDF

Info

Publication number
DK376986A
DK376986A DK376986A DK376986A DK376986A DK 376986 A DK376986 A DK 376986A DK 376986 A DK376986 A DK 376986A DK 376986 A DK376986 A DK 376986A DK 376986 A DK376986 A DK 376986A
Authority
DK
Denmark
Prior art keywords
tert
procedures
preparing
butylphenol compounds
butylphenol
Prior art date
Application number
DK376986A
Other languages
English (en)
Other versions
DK169324B1 (da
DK376986D0 (da
Inventor
Jill Ann Panetta
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK376986D0 publication Critical patent/DK376986D0/da
Publication of DK376986A publication Critical patent/DK376986A/da
Application granted granted Critical
Publication of DK169324B1 publication Critical patent/DK169324B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/16Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DK376986A 1985-08-09 1986-08-07 Di-tert-butylphenol-forbindelser, anvendelse af disse til fremstilling af farmaceutiske formuleringer, farmaceutiske formuleringer indeholdende forbindelserne samt fremgangsmåde til fremstilling af forbindelserne DK169324B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US76416085A 1985-08-09 1985-08-09
US76416085 1985-08-09
US86948886A 1986-06-02 1986-06-02
US86948886 1986-06-02

Publications (3)

Publication Number Publication Date
DK376986D0 DK376986D0 (da) 1986-08-07
DK376986A true DK376986A (da) 1987-02-10
DK169324B1 DK169324B1 (da) 1994-10-10

Family

ID=27117408

Family Applications (1)

Application Number Title Priority Date Filing Date
DK376986A DK169324B1 (da) 1985-08-09 1986-08-07 Di-tert-butylphenol-forbindelser, anvendelse af disse til fremstilling af farmaceutiske formuleringer, farmaceutiske formuleringer indeholdende forbindelserne samt fremgangsmåde til fremstilling af forbindelserne

Country Status (24)

Country Link
EP (1) EP0211670B1 (da)
JP (1) JPH0625182B2 (da)
KR (1) KR870000889B1 (da)
CN (1) CN1014891B (da)
AR (1) AR243173A1 (da)
AU (1) AU590312B2 (da)
CA (1) CA1285572C (da)
CY (1) CY1619A (da)
DE (1) DE3670951D1 (da)
DK (1) DK169324B1 (da)
ES (1) ES2001075A6 (da)
GR (1) GR862081B (da)
HK (1) HK94791A (da)
HU (1) HU196192B (da)
IE (1) IE58718B1 (da)
IL (1) IL79648A (da)
LV (1) LV10866B (da)
MX (1) MX9203108A (da)
MY (1) MY102365A (da)
NZ (1) NZ217126A (da)
PH (1) PH24517A (da)
PT (1) PT83152B (da)
SG (1) SG80391G (da)
SU (1) SU1516012A3 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8512163D0 (en) * 1985-05-14 1985-06-19 Fujisawa Pharmaceutical Co Oxothiazolidine compound
US5356917A (en) * 1985-08-09 1994-10-18 Eli Lilly And Company Aryl-substituted rhodanine derivatives
US5691367A (en) * 1985-08-09 1997-11-25 Eli Lilly And Company Aryl-substituted rhodanine derivatives
US4897406A (en) * 1987-11-13 1990-01-30 Nisshin Flour Milling Co., Ltd. Rhodanine derivatives and pharmaceutical compositions
US5208250A (en) * 1988-05-25 1993-05-04 Warner-Lambert Company Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents
US5306822A (en) * 1988-05-25 1994-04-26 Warner-Lambert Company Arylmethylenyl derivatives of oxazolidinone
IE940525L (en) * 1988-05-25 1989-11-25 Warner Lambert Co Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents
NZ231534A (en) * 1988-11-29 1992-02-25 Warner Lambert Co 3,5-di-t-butyl-4-hydroxyphenyl-triazoles, oxadiazoles and thiadiazoles; anti-inflammatory compositions
ES2088965T3 (es) * 1989-04-07 1996-10-01 Lilly Co Eli Derivados de rodanina aril-sustituidos.
ZA9010041B (en) * 1989-12-21 1992-08-26 Lilly Co Eli Compounds for treating inflammatory bowel disease
US5216002A (en) * 1989-12-21 1993-06-01 Eli Lilly And Company Method of treating inflammatory bowel disease
US5143928A (en) * 1990-03-27 1992-09-01 Warner-Lambert Company 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
WO1991017151A1 (en) * 1990-04-27 1991-11-14 Orion-Yhtymä Oy New pharmacologically active catechol derivatives
DE69221794T2 (de) * 1991-01-21 1998-03-19 Shionogi Seiyaku Kk 3-benzyliden-1-carbamoyl-2-pyrrolidon-analoga
US5158966A (en) * 1991-02-22 1992-10-27 The University Of Colorado Foundation, Inc. Method of treating type i diabetes
US5143929A (en) * 1991-05-09 1992-09-01 Warner-Lambert Company 2-substituted thiazolidinone, oxazolidinone, and imidazolidinone derivatives of fenamates as antiinflammatory agents
ZA936492B (en) * 1992-09-10 1995-03-02 Lilly Co Eli Compounds useful as hypoglycemic agents and for treating Alzheimer's disease.
DE69301894T2 (de) * 1992-10-28 1996-11-07 Shionogi & Co Benzylidenderivate
RO115518B1 (ro) * 1993-06-23 2000-03-30 Chugai Pharmaceutical Co Ltd Derivati de benzen utilizabili in boli ischemice
US6251928B1 (en) 1994-03-16 2001-06-26 Eli Lilly And Company Treatment of alzheimer's disease employing inhibitors of cathepsin D
US5476865A (en) * 1994-07-06 1995-12-19 Eli Lilly And Company Methods of inhibiting bone loss
CZ233897A3 (cs) * 1995-01-23 1998-03-18 Eli Lilly And Company Arylovou skupinou substituovaný derivát rhodaninu pro použití jako činidlo pro léčení roztroušené sklerózy savců a farmaceutický prostředek, který ho obsahuje
ATE193284T1 (de) * 1995-09-07 2000-06-15 Lilly Co Eli Verfahren zur herstellung von benzylsubstituierten rhodaninederivaten
TR199900040T2 (xx) * 1996-07-11 1999-04-21 Warner-Lambert Company N�ro dejeneratif hastal�klar�n bir thiazolidinon verilerek tedavisi ve �nlenmesi i�in y�ntem.
US6063799A (en) * 1996-09-03 2000-05-16 Eli Lilly And Company Alternate crystal form of Tazofelone
US6005142A (en) * 1996-09-03 1999-12-21 Eli Lilly And Company Process for preparing benzyl-substituted rhodanine derivatives
WO2000018748A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Rhodanine derivatives for the treatment and prevention of metabolic bone disorders
AU2002953533A0 (en) * 2002-12-24 2003-01-16 Arthron Limited Fc receptor modulating compounds and compositions
DE202006018406U1 (de) 2006-12-05 2008-04-10 Seda S.P.A. Verpackung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1038050B (de) * 1955-11-17 1958-09-04 Farmaceutici Italia S A Soc Verfahren zur Herstellung von 5-(3', 4'-Dioxybenzyliden)-Derivaten heterocyclischer Verbindungen
JPS5697277A (en) * 1980-01-07 1981-08-05 Takeda Chem Ind Ltd Thiazolidine derivative
JPS5740478A (en) * 1980-08-22 1982-03-06 Ono Pharmaceut Co Ltd Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative
JPS5879944A (ja) * 1981-11-09 1983-05-13 Kanegafuchi Chem Ind Co Ltd 3,5−ジ・タ−シヤリ−・ブチルスチレン誘導体及び抗炎症、鎮痛、解熱剤並びに血小板凝集阻害剤
JPS57130950A (en) * 1981-02-05 1982-08-13 Kanegafuchi Chem Ind Co Ltd 3,5-di-tert-butyl-4-hydroxystyrene derivative and anti- inflammatory, analgesic, antipyretic agent and inhibitor for blood platelet aggregation
US4636516A (en) * 1981-02-19 1987-01-13 Yamanouchi Pharmaceutical Co., Ltd. 3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds

Also Published As

Publication number Publication date
DK169324B1 (da) 1994-10-10
DK376986D0 (da) 1986-08-07
HK94791A (en) 1991-11-29
EP0211670B1 (en) 1990-05-09
AU6097286A (en) 1987-02-12
SG80391G (en) 1991-11-15
PT83152B (pt) 1989-03-30
NZ217126A (en) 1989-01-27
KR870002109A (ko) 1987-03-30
GR862081B (en) 1986-12-24
LV10866B (en) 1996-04-20
SU1516012A3 (ru) 1989-10-15
CN86105036A (zh) 1987-02-04
IL79648A0 (en) 1986-11-30
AR243173A1 (es) 1993-07-30
CA1285572C (en) 1991-07-02
CN1014891B (zh) 1991-11-27
DE3670951D1 (de) 1990-06-13
JPS6242977A (ja) 1987-02-24
PH24517A (en) 1990-07-18
LV10866A (lv) 1995-10-20
MY102365A (en) 1992-06-17
EP0211670A2 (en) 1987-02-25
MX9203108A (es) 1992-07-01
EP0211670A3 (en) 1987-05-06
IE58718B1 (en) 1993-11-03
HU196192B (en) 1988-10-28
AU590312B2 (en) 1989-11-02
IL79648A (en) 1991-12-12
HUT42765A (en) 1987-08-28
PT83152A (en) 1986-09-01
KR870000889B1 (ko) 1987-05-02
CY1619A (en) 1992-07-10
ES2001075A6 (es) 1988-04-16
JPH0625182B2 (ja) 1994-04-06

Similar Documents

Publication Publication Date Title
DK376986D0 (da) Di-tert-butylphenol-forbindelser og fremgangsmaade til fremstilling heraf
DK313086D0 (da) Phenoxyalkylisoxazol- eller -furanforbindelse og fremgangsmaade til fremstilling deraf
DK491186A (da) Pyridonderivater og fremgangsmaade til fremstilling deraf
DK51286A (da) Desoxyadenosinphosphatforbindelser og fremgangsmaade til fremstilling afdisse
DK301886A (da) Furanon-derivater og fremgangsmaade til fremstilling heraf
DK437286A (da) 2,5-diaryl-tetrahydrothiophenforbindelse og fremgangsmaade til fremstilling deraf
DK335986A (da) Poly-4-aminopropyl-2-carboxamidoderivat og fremgangsmaade til fremstilling deraf
DK82686D0 (da) (1-benzyl-ethylendiamin)-platin(ii)-komplekser og fremgangsmaade til fremstilling heraf
DK315085D0 (da) Isoinsolinyl-alkyl-piperaziner og fremgangsmaade til fremstilling deraf
DK621484D0 (da) Acylaminomitosaner og fremgangsmaade til fremstilling deraf
DK4187D0 (da) Triazolylquinolin-derivater og fremgangsmaade til fremstilling deraf
DK251087D0 (da) Dopamin-beta-hydrolaseinhibitorer og fremgangsmaade til fremstilling deraf
DK401385A (da) 7-oxomitosan-derivater og fremgangsmaade til fremstilling deraf
NO863469D0 (no) Herbicid og fremgangsmaate for anvendelse derav.
DK317786A (da) Antibakterielt virksomme 7beta-heteroacylamino-4-chlor-cephalosporiner og fremgangsmaade til fremstilling heraf
DK446685A (da) Carbapenemderivater og fremgangsmaade til fremstilling deraf
DK165634C (da) Arylsulfonforbindelser og fremgangsmaader til fremstilling deraf
DK50686D0 (da) Difficolforbindelse og fremgangsmaade til fremstilling deraf
DK182585D0 (da) Fosfomycinderivat og fremgangsmaade til fremstilling deraf
NO170761C (no) Askorbat-2-polyfosfatforbindelser og fremgangsmaate til fremstilling derav
DK284184A (da) 1-phenoxy-3-hydroxyindolylalkylamino-3-propanoler og fremgangsmaade til fremstilling deraf
DK230286A (da) Phosphinguldforbindelser og fremgangsmaade til fremstilling deraf
DK301785A (da) Tert-butyl-gamma-dimethylamino-beta-hydroxybutyrat og fremgangsmaadetil fremstilling deraf
DK319188D0 (da) Glycerolacetalaminoacylat og fremgangsmaade til fremstilling deraf
DK53887D0 (da) Emulgator og fremgangsmaade til fremstilling deraf

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

Country of ref document: DK