DK3643795T3 - Fremganffremgangsmåde til bestemmelse af celle- eller vævsdød ved analyse af dna-methylering - Google Patents
Fremganffremgangsmåde til bestemmelse af celle- eller vævsdød ved analyse af dna-methylering Download PDFInfo
- Publication number
- DK3643795T3 DK3643795T3 DK19209237.7T DK19209237T DK3643795T3 DK 3643795 T3 DK3643795 T3 DK 3643795T3 DK 19209237 T DK19209237 T DK 19209237T DK 3643795 T3 DK3643795 T3 DK 3643795T3
- Authority
- DK
- Denmark
- Prior art keywords
- analysis
- dna methylation
- determining cell
- tissue death
- death
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461979233P | 2014-04-14 | 2014-04-14 | |
| EP15720481.9A EP3132055A2 (de) | 2014-04-14 | 2015-04-14 | Verfahren und kit zur bestimmung des gewebe- oder zellursprungs von dna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3643795T3 true DK3643795T3 (da) | 2022-05-09 |
Family
ID=53051869
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19209237.7T DK3643795T3 (da) | 2014-04-14 | 2015-04-14 | Fremganffremgangsmåde til bestemmelse af celle- eller vævsdød ved analyse af dna-methylering |
| DK22158931.0T DK4026917T5 (da) | 2014-04-14 | 2015-04-14 | Fremgangsmåde og kit til bestemmelse af cellers eller vævs død eller dna's vævs- eller celleoprindelse ved dna-methyleringsanalyse |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK22158931.0T DK4026917T5 (da) | 2014-04-14 | 2015-04-14 | Fremgangsmåde og kit til bestemmelse af cellers eller vævs død eller dna's vævs- eller celleoprindelse ved dna-methyleringsanalyse |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11203784B2 (de) |
| EP (4) | EP3643795B1 (de) |
| JP (1) | JP6750879B2 (de) |
| CN (1) | CN106574296B (de) |
| DK (2) | DK3643795T3 (de) |
| ES (1) | ES2974838T3 (de) |
| FI (1) | FI4026917T3 (de) |
| HR (1) | HRP20240189T1 (de) |
| IL (1) | IL248299B (de) |
| LT (1) | LT4026917T (de) |
| PL (1) | PL4026917T3 (de) |
| PT (1) | PT4026917T (de) |
| SI (1) | SI4026917T1 (de) |
| WO (2) | WO2015159293A2 (de) |
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|---|---|---|---|---|
| US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US10876152B2 (en) | 2012-09-04 | 2020-12-29 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US11913065B2 (en) | 2012-09-04 | 2024-02-27 | Guardent Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| CA2883901C (en) | 2012-09-04 | 2023-04-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| EP3087204B1 (de) | 2013-12-28 | 2018-02-14 | Guardant Health, Inc. | Verfahren und systeme für den nachweis genetischer varianten |
| PL4026917T3 (pl) | 2014-04-14 | 2024-04-08 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. | Metoda i zestaw do określania śmierci komórek lub tkanek albo tkankowego lub komórkowego pochodzenia dna za pomocą analizy metylacji dna |
| DK3543356T3 (da) | 2014-07-18 | 2021-10-11 | Univ Hong Kong Chinese | Analyse af methyleringsmønster af væv i DNA-blanding |
| US10689706B2 (en) | 2015-07-20 | 2020-06-23 | The Chinese University Of Hong Kong | Methylation pattern analysis of haplotypes in tissues in a DNA mixture |
| CN108603228B (zh) | 2015-12-17 | 2023-09-01 | 夸登特健康公司 | 通过分析无细胞dna确定肿瘤基因拷贝数的方法 |
| US11384382B2 (en) | 2016-04-14 | 2022-07-12 | Guardant Health, Inc. | Methods of attaching adapters to sample nucleic acids |
| WO2017181146A1 (en) | 2016-04-14 | 2017-10-19 | Guardant Health, Inc. | Methods for early detection of cancer |
| US20190256921A1 (en) * | 2016-05-04 | 2019-08-22 | Queen's University At Kingston | Cell-free detection of methylated tumour dna |
| KR102482616B1 (ko) * | 2016-05-30 | 2022-12-28 | 더 차이니즈 유니버시티 오브 홍콩 | 혈액 내 무세포 dna를 사용하는 혈액 장애의 검출 |
| US11499196B2 (en) | 2016-06-07 | 2022-11-15 | The Regents Of The University Of California | Cell-free DNA methylation patterns for disease and condition analysis |
| US11124824B2 (en) | 2016-08-17 | 2021-09-21 | The Regents Of The University Of California | Immunoprobe-based method to assess organ injury status through a biofluid-based cell-free DNA (CFDNA) assay |
| US11959125B2 (en) * | 2016-09-15 | 2024-04-16 | Sun Genomics, Inc. | Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample |
| AU2017347790B2 (en) | 2016-10-24 | 2024-06-13 | Grail, Inc. | Methods and systems for tumor detection |
| KR20230062684A (ko) | 2016-11-30 | 2023-05-09 | 더 차이니즈 유니버시티 오브 홍콩 | 소변 및 기타 샘플에서의 무세포 dna의 분석 |
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| EP4421489A2 (de) | 2017-01-25 | 2024-08-28 | The Chinese University of Hong Kong | Diagnostische anwendungen unter verwendung von nukleinsäurefragmenten |
| WO2018187521A2 (en) | 2017-04-06 | 2018-10-11 | Cornell University | Methods of detecting cell-free dna in biological samples |
| CN111032868A (zh) * | 2017-06-30 | 2020-04-17 | 加利福尼亚大学董事会 | 用于评估无细胞dna中的dna甲基化的方法和系统 |
| US20200165671A1 (en) * | 2017-07-13 | 2020-05-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Detecting tissue-specific dna |
| EP3652343A1 (de) | 2017-07-13 | 2020-05-20 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Digitale tröpfchen-pcr-strategie mit zwei sonden zur spezifischen detektion gewebespezifischer zirkulierender dna-moleküle |
| EP3652344A1 (de) | 2017-07-13 | 2020-05-20 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Dna-targets als gewebespezifische methylierungsmarker |
| DE102017126248B4 (de) * | 2017-11-09 | 2019-10-17 | Epiontis Gmbh | ERGIC1 als epigenetischer Marker zur Identifizierung von Immunzellen, insbesonderemonozytischem myeloid-abgeleiteten Suppressor-Zellen (mMDSCs) |
| WO2019159184A1 (en) * | 2018-02-18 | 2019-08-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Cell free dna deconvolution and use thereof |
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| EP3766076A4 (de) * | 2018-03-15 | 2021-12-29 | Grail, Inc. | Gewebespezifischer methylierungsmarker |
| CA3094717A1 (en) | 2018-04-02 | 2019-10-10 | Grail, Inc. | Methylation markers and targeted methylation probe panels |
| WO2019209884A1 (en) | 2018-04-23 | 2019-10-31 | Grail, Inc. | Methods and systems for screening for conditions |
| JP2021112127A (ja) * | 2018-04-26 | 2021-08-05 | 暁生 黒田 | 膵β細胞の傷害検査方法 |
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| CN113286881A (zh) | 2018-09-27 | 2021-08-20 | 格里尔公司 | 甲基化标记和标靶甲基化探针板 |
| GB2595076B8 (en) | 2018-11-21 | 2023-08-23 | Agilent Technologies Inc | Methods for targeted nucleic acid library formation |
| US11581062B2 (en) | 2018-12-10 | 2023-02-14 | Grail, Llc | Systems and methods for classifying patients with respect to multiple cancer classes |
| AU2019401636A1 (en) * | 2018-12-18 | 2021-06-17 | Grail, Llc | Systems and methods for estimating cell source fractions using methylation information |
| US11902959B2 (en) * | 2019-02-02 | 2024-02-13 | Lenovo (Beijing) Limited | Enhanced scheduling of time sensitive networking |
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| US20220064731A1 (en) * | 2019-04-03 | 2022-03-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Primers for multiplex pcr |
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| US11001898B2 (en) | 2019-05-31 | 2021-05-11 | Universal Diagnostics, S.L. | Detection of colorectal cancer |
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| JP2024534992A (ja) | 2021-09-13 | 2024-09-26 | プログノミック インコーポレイテッド | 生体分子の増強された検出および定量 |
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| EP3652343A1 (de) | 2017-07-13 | 2020-05-20 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Digitale tröpfchen-pcr-strategie mit zwei sonden zur spezifischen detektion gewebespezifischer zirkulierender dna-moleküle |
| EP3652344A1 (de) | 2017-07-13 | 2020-05-20 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Dna-targets als gewebespezifische methylierungsmarker |
-
2015
- 2015-04-14 PL PL22158931.0T patent/PL4026917T3/pl unknown
- 2015-04-14 LT LTEP22158931.0T patent/LT4026917T/lt unknown
- 2015-04-14 EP EP19209237.7A patent/EP3643795B1/de active Active
- 2015-04-14 WO PCT/IL2015/050404 patent/WO2015159293A2/en active Application Filing
- 2015-04-14 EP EP23209884.8A patent/EP4306659A3/de active Pending
- 2015-04-14 FI FIEP22158931.0T patent/FI4026917T3/fi active
- 2015-04-14 PT PT221589310T patent/PT4026917T/pt unknown
- 2015-04-14 EP EP22158931.0A patent/EP4026917B1/de active Active
- 2015-04-14 EP EP15720481.9A patent/EP3132055A2/de not_active Ceased
- 2015-04-14 DK DK19209237.7T patent/DK3643795T3/da active
- 2015-04-14 US US15/303,762 patent/US11203784B2/en active Active
- 2015-04-14 WO PCT/IL2015/050403 patent/WO2015159292A2/en active Application Filing
- 2015-04-14 DK DK22158931.0T patent/DK4026917T5/da active
- 2015-04-14 SI SI201531988T patent/SI4026917T1/sl unknown
- 2015-04-14 JP JP2016562026A patent/JP6750879B2/ja active Active
- 2015-04-14 HR HRP20240189TT patent/HRP20240189T1/hr unknown
- 2015-04-14 ES ES22158931T patent/ES2974838T3/es active Active
- 2015-04-14 CN CN201580031764.XA patent/CN106574296B/zh active Active
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2023
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Also Published As
| Publication number | Publication date |
|---|---|
| IL248299A0 (en) | 2016-11-30 |
| PT4026917T (pt) | 2024-02-12 |
| EP4026917B1 (de) | 2023-11-15 |
| EP4026917A1 (de) | 2022-07-13 |
| IL248299B (en) | 2021-04-29 |
| DK4026917T5 (da) | 2024-07-15 |
| US20170121767A1 (en) | 2017-05-04 |
| JP6750879B2 (ja) | 2020-09-02 |
| EP3132055A2 (de) | 2017-02-22 |
| US20220064730A1 (en) | 2022-03-03 |
| WO2015159292A2 (en) | 2015-10-22 |
| EP4306659A2 (de) | 2024-01-17 |
| DK4026917T3 (da) | 2024-02-12 |
| PL4026917T3 (pl) | 2024-04-08 |
| WO2015159292A3 (en) | 2015-12-10 |
| EP3643795B1 (de) | 2022-03-30 |
| JP2017511142A (ja) | 2017-04-20 |
| WO2015159293A2 (en) | 2015-10-22 |
| EP3643795A1 (de) | 2020-04-29 |
| LT4026917T (lt) | 2024-03-12 |
| US20230242985A1 (en) | 2023-08-03 |
| FI4026917T3 (fi) | 2024-02-14 |
| HRP20240189T1 (hr) | 2024-04-26 |
| US11203784B2 (en) | 2021-12-21 |
| SI4026917T1 (sl) | 2024-05-31 |
| EP4306659A3 (de) | 2024-03-27 |
| CN106574296A (zh) | 2017-04-19 |
| ES2974838T3 (es) | 2024-07-01 |
| WO2015159293A3 (en) | 2015-12-10 |
| CN106574296B (zh) | 2021-03-02 |
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