DK3641888T3 - Plasminogenbehandling af tilstande forbundet med pai-1-overekspression - Google Patents
Plasminogenbehandling af tilstande forbundet med pai-1-overekspression Download PDFInfo
- Publication number
- DK3641888T3 DK3641888T3 DK18821458.9T DK18821458T DK3641888T3 DK 3641888 T3 DK3641888 T3 DK 3641888T3 DK 18821458 T DK18821458 T DK 18821458T DK 3641888 T3 DK3641888 T3 DK 3641888T3
- Authority
- DK
- Denmark
- Prior art keywords
- pai
- overexpression
- conditions associated
- plasminogen treatment
- plasminogen
- Prior art date
Links
- 102000013566 Plasminogen Human genes 0.000 title 1
- 108010051456 Plasminogen Proteins 0.000 title 1
- 102000012335 Plasminogen Activator Inhibitor 1 Human genes 0.000 title 1
- 108010022233 Plasminogen Activator Inhibitor 1 Proteins 0.000 title 1
- 230000002018 overexpression Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/484—Plasmin (3.4.21.7)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762523901P | 2017-06-23 | 2017-06-23 | |
| PCT/IB2018/000655 WO2018234861A1 (en) | 2017-06-23 | 2018-06-22 | PLASMINOGEN TREATMENT OF AFFECTIONS ASSOCIATED WITH OVEREXPRESSION OF PAI-1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3641888T3 true DK3641888T3 (da) | 2024-01-02 |
Family
ID=64737041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18821458.9T DK3641888T3 (da) | 2017-06-23 | 2018-06-22 | Plasminogenbehandling af tilstande forbundet med pai-1-overekspression |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US11826404B2 (da) |
| EP (1) | EP3641888B1 (da) |
| JP (1) | JP2020524689A (da) |
| KR (1) | KR20200019217A (da) |
| CN (1) | CN110831668B (da) |
| AU (1) | AU2018287316B2 (da) |
| BR (1) | BR112019027229A2 (da) |
| CA (1) | CA3068153A1 (da) |
| CL (1) | CL2019003789A1 (da) |
| DK (1) | DK3641888T3 (da) |
| ES (1) | ES2965937T3 (da) |
| FI (1) | FI3641888T3 (da) |
| IL (1) | IL271470A (da) |
| MX (1) | MX2019015741A (da) |
| RU (1) | RU2020100080A (da) |
| SG (1) | SG11201912813SA (da) |
| TW (1) | TW201904990A (da) |
| WO (1) | WO2018234861A1 (da) |
| ZA (1) | ZA202000280B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110114079A (zh) | 2016-12-15 | 2019-08-09 | 泰伦基国际有限公司 | 一种预防和治疗肥胖症的方法和药物 |
| TWI750189B (zh) | 2016-12-15 | 2021-12-21 | 大陸商深圳瑞健生命科學研究院有限公司 | 一種治療冠狀動脈粥樣硬化及其併發症的方法 |
| CA3047175A1 (en) | 2016-12-15 | 2018-06-21 | Talengen International Limited | Method for mitigating heart disease |
| CN115427066A (zh) * | 2020-02-06 | 2022-12-02 | 泰伦基国际有限公司 | 一种预防和治疗多发性硬化症的方法和药物 |
| KR20220158036A (ko) * | 2020-03-24 | 2022-11-29 | 탈렌젠 인터내셔널 리미티드 | 파킨슨병의 치료 방법 및 약물 |
| CA3176937A1 (en) * | 2020-03-24 | 2021-09-30 | Talengen International Limited | Method and drug for promoting degradation of misfolded protein and aggregate thereof |
| KR20220156927A (ko) * | 2020-03-24 | 2022-11-28 | 탈렌젠 인터내셔널 리미티드 | 알츠하이머병의 치료 방법 및 약물 |
| CN112174979B (zh) * | 2020-10-27 | 2021-09-07 | 黑龙江中医药大学 | 一种治疗多囊卵巢综合征的药物及其制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5520912A (en) | 1993-07-02 | 1996-05-28 | Immuno Aktiengesellschaft | Prevention and treatment of ischemic events and reperfusion injury resulting therefrom using lys-plasminogen |
| US6677473B1 (en) * | 1999-11-19 | 2004-01-13 | Corvas International Inc | Plasminogen activator inhibitor antagonists |
| AU3173301A (en) * | 2000-02-11 | 2001-08-20 | European Molecular Biology Laboratory | Methods and compositions for treatment of alzheimer's disease by enhancing plasmin or plasmin-like activity |
| GB0509438D0 (en) | 2005-05-09 | 2005-06-15 | Prometic Biosciences Ltd | Affinity adsorbets for fibrinogen |
| CN101573134B (zh) * | 2006-08-28 | 2013-03-06 | 李季男 | 抗感染候选药物 |
| US20100028321A1 (en) | 2006-08-28 | 2010-02-04 | Omnio Healer Ab | Drug target for preventing and treating periodontal disease, improving healing of periodontal wounds and promoting oral health |
| JP6696899B2 (ja) * | 2013-08-13 | 2020-05-20 | サノフイＳａｎｏｆｉ | プラスミノーゲン活性化因子阻害剤−１（ｐａｉ−１）に対する抗体及びその使用 |
| TWI801331B (zh) | 2015-11-03 | 2023-05-11 | 美商波麥堤克生物治療股份有限公司 | 纖維蛋白溶酶原缺乏症之纖維蛋白溶酶原替代療法 |
| TW201722464A (zh) | 2015-11-10 | 2017-07-01 | 波麥堤克生化科學有限公司 | 用於傷口癒合之纖維蛋白溶酶原給藥方案 |
| CN110114079A (zh) * | 2016-12-15 | 2019-08-09 | 泰伦基国际有限公司 | 一种预防和治疗肥胖症的方法和药物 |
| EP3556388A4 (en) | 2016-12-15 | 2020-07-08 | Talengen International Limited | METHOD FOR PREVENTING AND TREATING PATHOLOGICAL KIDNEY DAMAGE |
| US11154595B2 (en) * | 2016-12-15 | 2021-10-26 | Talengen International Limited | Method for preventing and treating pulmonary fibrosis |
-
2018
- 2018-06-15 TW TW107120839A patent/TW201904990A/zh unknown
- 2018-06-22 RU RU2020100080A patent/RU2020100080A/ru unknown
- 2018-06-22 SG SG11201912813SA patent/SG11201912813SA/en unknown
- 2018-06-22 DK DK18821458.9T patent/DK3641888T3/da active
- 2018-06-22 EP EP18821458.9A patent/EP3641888B1/en active Active
- 2018-06-22 CN CN201880041573.5A patent/CN110831668B/zh active Active
- 2018-06-22 BR BR112019027229-1A patent/BR112019027229A2/pt not_active Application Discontinuation
- 2018-06-22 WO PCT/IB2018/000655 patent/WO2018234861A1/en active Application Filing
- 2018-06-22 JP JP2019570806A patent/JP2020524689A/ja active Pending
- 2018-06-22 CA CA3068153A patent/CA3068153A1/en active Pending
- 2018-06-22 FI FIEP18821458.9T patent/FI3641888T3/fi active
- 2018-06-22 AU AU2018287316A patent/AU2018287316B2/en active Active
- 2018-06-22 KR KR1020207001617A patent/KR20200019217A/ko unknown
- 2018-06-22 MX MX2019015741A patent/MX2019015741A/es unknown
- 2018-06-22 US US16/625,335 patent/US11826404B2/en active Active
- 2018-06-22 ES ES18821458T patent/ES2965937T3/es active Active
-
2019
- 2019-12-16 IL IL271470A patent/IL271470A/en unknown
- 2019-12-20 CL CL2019003789A patent/CL2019003789A1/es unknown
-
2020
- 2020-01-15 ZA ZA2020/00280A patent/ZA202000280B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201912813SA (en) | 2020-01-30 |
| EP3641888A1 (en) | 2020-04-29 |
| AU2018287316A1 (en) | 2020-02-06 |
| ZA202000280B (en) | 2021-08-25 |
| RU2020100080A3 (da) | 2021-11-02 |
| EP3641888A4 (en) | 2021-03-10 |
| MX2019015741A (es) | 2020-11-11 |
| IL271470A (en) | 2020-01-30 |
| CL2019003789A1 (es) | 2020-07-10 |
| TW201904990A (zh) | 2019-02-01 |
| AU2018287316B2 (en) | 2024-09-19 |
| RU2020100080A (ru) | 2021-07-23 |
| US11826404B2 (en) | 2023-11-28 |
| FI3641888T3 (fi) | 2023-12-19 |
| KR20200019217A (ko) | 2020-02-21 |
| ES2965937T3 (es) | 2024-04-17 |
| WO2018234861A1 (en) | 2018-12-27 |
| JP2020524689A (ja) | 2020-08-20 |
| US20210330761A1 (en) | 2021-10-28 |
| CN110831668A (zh) | 2020-02-21 |
| BR112019027229A2 (pt) | 2020-07-07 |
| CA3068153A1 (en) | 2018-12-27 |
| CN110831668B (zh) | 2024-04-12 |
| EP3641888B1 (en) | 2023-10-11 |
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