DK3558944T3 - Hydrogenering af et substitueret 2-methylcyanopyridylderivat i nærvær af en raney-cobaltkatalysator - Google Patents
Hydrogenering af et substitueret 2-methylcyanopyridylderivat i nærvær af en raney-cobaltkatalysator Download PDFInfo
- Publication number
- DK3558944T3 DK3558944T3 DK17818126.9T DK17818126T DK3558944T3 DK 3558944 T3 DK3558944 T3 DK 3558944T3 DK 17818126 T DK17818126 T DK 17818126T DK 3558944 T3 DK3558944 T3 DK 3558944T3
- Authority
- DK
- Denmark
- Prior art keywords
- methylcyanopyridyle
- hydrogenation
- derivative
- substituted
- cobalt catalyst
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16205582 | 2016-12-21 | ||
| PCT/EP2017/083321 WO2018114810A1 (en) | 2016-12-21 | 2017-12-18 | Catalytic hydrogenation of nitriles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3558944T3 true DK3558944T3 (da) | 2022-05-30 |
Family
ID=57583030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17818126.9T DK3558944T3 (da) | 2016-12-21 | 2017-12-18 | Hydrogenering af et substitueret 2-methylcyanopyridylderivat i nærvær af en raney-cobaltkatalysator |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10766859B2 (da) |
| EP (1) | EP3558944B1 (da) |
| JP (1) | JP7110200B2 (da) |
| KR (1) | KR102610959B1 (da) |
| CN (1) | CN110291069A (da) |
| BR (1) | BR112019012885B1 (da) |
| DK (1) | DK3558944T3 (da) |
| ES (1) | ES2912531T3 (da) |
| IL (1) | IL267481B (da) |
| MX (1) | MX2019007640A (da) |
| TW (1) | TWI762543B (da) |
| WO (1) | WO2018114810A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112552231B (zh) * | 2020-12-11 | 2022-03-11 | 南京正荣医药化学有限公司 | 一种2-(3-氯-5-(三氟甲基)吡啶-2-基)乙胺的合成方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE758296A (fr) | 1969-11-07 | 1971-04-01 | Rhodiatoce | Procede de fabrication d'hexamethylenediamine |
| DE2100373C3 (de) | 1971-01-15 | 1979-04-12 | Institut Chimitscheskich Nauk Akademii Nauk Kasachskoj Ssr | Katalysator zum Hydrieren von Nitroverbindungen |
| DE2101856C3 (de) | 1971-01-15 | 1974-11-07 | Kasachskij Gosudarstwenny Uniwersitet Imeni S.M. Kirowa, Alma-Ata (Sowjetunion) | Aluminium-Nickel-Legierung, insbesondere zur Verwendung als Katalysator für die Hydrierung von ungesättigten organischen Verbindungen |
| US4153578A (en) | 1978-07-31 | 1979-05-08 | Gaf Corporation | Catalyst comprising Raney nickel with adsorbed molybdenum compound |
| DE4222152A1 (de) * | 1992-07-06 | 1994-01-13 | Bayer Ag | Verfahren zur Herstellung von 2-Chlor-5-aminomethyl-pyridin |
| PL224002B1 (pl) * | 2002-08-12 | 2016-11-30 | Bayer Sas | Pochodna 2-pirydyloetylobenzamidu, zawierająca ją kompozycja grzybobójcza i sposób zapobiegawczego lub leczniczego zwalczania grzybów chorobotwórczych dla roślin w uprawach |
| EP1560488B1 (en) | 2002-11-05 | 2010-09-01 | Glaxo Group Limited | Antibacterial agents |
| EP1500651A1 (en) * | 2003-07-25 | 2005-01-26 | Bayer CropScience S.A. | N-[2-(2-Pyridinyl)ethyl]benzamide compounds and their use as fungicides |
| US8232426B2 (en) | 2004-10-14 | 2012-07-31 | Abbott Gmbh & Co. Kg | Aminoethylaromatic compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor |
| EP1674455A1 (en) | 2004-12-21 | 2006-06-28 | Bayer CropScience S.A. | Process for the preparation of a 2-ethylaminopyridine derivative |
| CN101277939A (zh) * | 2005-09-09 | 2008-10-01 | 布里斯托尔-迈尔斯斯奎布公司 | 无环ikur抑制剂 |
| EP2010009B1 (en) * | 2006-04-21 | 2017-06-14 | Senomyx, Inc. | Processes for preparing solid flavorant compositions |
| ATE496045T1 (de) | 2007-04-12 | 2011-02-15 | Hoffmann La Roche | Pyrimidinderivate als inhibitoren von phosphatidylinositol-3-kinase |
| WO2011047156A1 (en) | 2009-10-15 | 2011-04-21 | Hercules Technology Management Co V, Inc. | Sepiapterin reductase inhibitors for the treatment of pain |
| DK3068766T3 (da) * | 2013-11-15 | 2018-04-23 | Bayer Cropscience Ag | Katalytisk hydrogenering af nitriler |
-
2017
- 2017-12-18 US US16/471,144 patent/US10766859B2/en active Active
- 2017-12-18 CN CN201780087037.4A patent/CN110291069A/zh active Pending
- 2017-12-18 KR KR1020197020742A patent/KR102610959B1/ko active IP Right Grant
- 2017-12-18 WO PCT/EP2017/083321 patent/WO2018114810A1/en unknown
- 2017-12-18 BR BR112019012885-9A patent/BR112019012885B1/pt active IP Right Grant
- 2017-12-18 ES ES17818126T patent/ES2912531T3/es active Active
- 2017-12-18 JP JP2019533402A patent/JP7110200B2/ja active Active
- 2017-12-18 DK DK17818126.9T patent/DK3558944T3/da active
- 2017-12-18 EP EP17818126.9A patent/EP3558944B1/en active Active
- 2017-12-18 MX MX2019007640A patent/MX2019007640A/es unknown
- 2017-12-19 TW TW106144526A patent/TWI762543B/zh active
-
2019
- 2019-06-19 IL IL267481A patent/IL267481B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US10766859B2 (en) | 2020-09-08 |
| US20200039936A1 (en) | 2020-02-06 |
| CN110291069A (zh) | 2019-09-27 |
| JP2020503308A (ja) | 2020-01-30 |
| BR112019012885A2 (pt) | 2019-11-26 |
| EP3558944A1 (en) | 2019-10-30 |
| WO2018114810A1 (en) | 2018-06-28 |
| KR102610959B1 (ko) | 2023-12-06 |
| TW201835046A (zh) | 2018-10-01 |
| JP7110200B2 (ja) | 2022-08-01 |
| ES2912531T3 (es) | 2022-05-26 |
| BR112019012885B1 (pt) | 2022-12-27 |
| MX2019007640A (es) | 2019-09-06 |
| IL267481A (en) | 2019-08-29 |
| EP3558944B1 (en) | 2022-03-09 |
| IL267481B (en) | 2022-04-01 |
| TWI762543B (zh) | 2022-05-01 |
| KR20190092562A (ko) | 2019-08-07 |
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