DK353781A - Fremgangsmaade til fremstilling af insulinderivater - Google Patents
Fremgangsmaade til fremstilling af insulinderivaterInfo
- Publication number
- DK353781A DK353781A DK353781A DK353781A DK353781A DK 353781 A DK353781 A DK 353781A DK 353781 A DK353781 A DK 353781A DK 353781 A DK353781 A DK 353781A DK 353781 A DK353781 A DK 353781A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- preparation
- insulin derivatives
- insulin
- derivatives
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical class N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK353781A DK353781A (da) | 1981-08-10 | 1981-08-10 | Fremgangsmaade til fremstilling af insulinderivater |
| DK346682A DK149314C (da) | 1981-08-10 | 1982-08-03 | Fremgangsmaade til fremstilling af humaninsulin eller threonin-b30-derivater af humaninsulin eller et salt eller kompleks deraf |
| CA000408994A CA1174973A (en) | 1981-08-10 | 1982-08-09 | Process for preparing polypeptide derivatives |
| FR8213868A FR2511036B1 (fr) | 1981-08-10 | 1982-08-09 | Procede de preparation de derives d'insuline et produits obtenus |
| AU86974/82A AU549066B2 (en) | 1981-08-10 | 1982-08-09 | Preparation of human insulin |
| AT0303582A AT374683B (de) | 1981-08-10 | 1982-08-09 | Verfahren zur herstellung von humaninsulin, threoninderivaten, salzen oder komplexen davon |
| IE1911/82A IE53712B1 (en) | 1981-08-10 | 1982-08-09 | Process for preparing polypeptide derivatives |
| NLAANVRAGE8203137,A NL182964C (nl) | 1981-08-10 | 1982-08-09 | Werkwijze voor het bereiden van menselijke insuline. |
| US06/406,571 US4489159A (en) | 1981-08-10 | 1982-08-09 | Process for preparing esters of human insulin |
| LU84327A LU84327A1 (de) | 1981-08-10 | 1982-08-09 | Verfahren zur herstellung von humanisulin,threoninderivaten,salzen oder komplexen davon |
| GB08222914A GB2105342B (en) | 1981-08-10 | 1982-08-09 | Process for preparing polypeptide derivatives |
| DE19823229674 DE3229674A1 (de) | 1981-08-10 | 1982-08-09 | Verfahren zur herstellung von humaninsulin, threoninderivaten, salzen oder komplexen davon |
| IT22784/82A IT1152492B (it) | 1981-08-10 | 1982-08-09 | Processo per la preparazione di derivati dell'insulina |
| NO822704A NO157506C (no) | 1981-08-10 | 1982-08-09 | Fremgangsmaate for fremstilling av human-insulin eller treoninb30-derivater av human-insulin eller et salt eller kompleks derav. |
| CH4775/82A CH661746A5 (de) | 1981-08-10 | 1982-08-09 | Verfahren zur herstellung von humaninsulin oder von threonin b30-estern von humaninsulin, oder von einem salz oder einem metallkomplex derselben, sowie diese ester. |
| BE6/47694A BE894070A (fr) | 1981-08-10 | 1982-08-09 | Procede de preparation de derives d'insuline et produits obtenus |
| GR68986A GR77999B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1981-08-10 | 1982-08-09 | |
| SE8204627A SE451073B (sv) | 1981-08-10 | 1982-08-09 | Forfarande for framstellning av insulinderivat |
| ES514845A ES514845A0 (es) | 1981-08-10 | 1982-08-09 | "un procedimiento para preparar insulina humana o derivados de treomina b30 de insulina humana". |
| FI822773A FI79142C (fi) | 1981-08-10 | 1982-08-09 | Foerfarande foer framstaellning av insulinderivat. |
| JP57138095A JPS5836399A (ja) | 1981-08-10 | 1982-08-10 | ヒトインシユリン誘導体の製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK353781A DK353781A (da) | 1981-08-10 | 1981-08-10 | Fremgangsmaade til fremstilling af insulinderivater |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK353781A true DK353781A (da) | 1983-02-11 |
Family
ID=8124014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK353781A DK353781A (da) | 1981-08-10 | 1981-08-10 | Fremgangsmaade til fremstilling af insulinderivater |
Country Status (20)
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5776693A (en) * | 1990-06-08 | 1998-07-07 | Institut Pasteur | Specific detection of the mycobacterium tuberculosis |
| AU1111799A (en) | 1997-10-24 | 1999-05-17 | Eli Lilly And Company | Fatty acid-acylated insulin analogs |
| US6531448B1 (en) | 1997-12-23 | 2003-03-11 | Eli Lilly And Company | Insoluble compositions for controlling blood glucose |
| US20080085298A1 (en) * | 2004-03-12 | 2008-04-10 | Biodel, Inc. | Rapid Mucosal Gel or Film Insulin Compositions |
| US20080090753A1 (en) | 2004-03-12 | 2008-04-17 | Biodel, Inc. | Rapid Acting Injectable Insulin Compositions |
| US20080096800A1 (en) * | 2004-03-12 | 2008-04-24 | Biodel, Inc. | Rapid mucosal gel or film insulin compositions |
| US7713929B2 (en) * | 2006-04-12 | 2010-05-11 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
| US8084420B2 (en) | 2005-09-29 | 2011-12-27 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
| EP2012817A2 (en) | 2006-04-12 | 2009-01-14 | Biodel, Inc. | Rapid acting and long acting insulin combination formulations |
| US9060927B2 (en) | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
| CN102471367A (zh) * | 2009-07-09 | 2012-05-23 | 拜康有限公司 | 一种制备非线性梯度色谱法及其纯化的产物 |
| WO2011090971A2 (en) | 2010-01-19 | 2011-07-28 | The Trustees Of Columbia University In The City Of New York | Osteocalcin as a treatment for male reproductive disorders |
| US10052364B2 (en) | 2013-03-15 | 2018-08-21 | The Trustees Of Columbia University In The City Of New York | Osteocalcin as a treatment for cognitive disorders |
| US10611813B2 (en) * | 2013-12-23 | 2020-04-07 | Biocon Research Limited | Method of production of human insulin methyl ester |
| EP3805247A1 (en) * | 2017-02-10 | 2021-04-14 | Mitsubishi Chemical Corporation | Separating agent for human insulin purification and human insulin purification method |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3276961A (en) * | 1963-04-08 | 1966-10-04 | Squibb & Sons Inc | Process for preparing human insulin |
| US3903068A (en) * | 1972-12-26 | 1975-09-02 | Us Health Education & Welfare | Facile synthesis of human insulin by modification of porcine insulin |
| JPS55138392A (en) * | 1979-04-13 | 1980-10-29 | Shionogi & Co Ltd | Semisynthesis of insulin |
| DK146482C (da) * | 1979-04-13 | 1986-10-06 | Shionogi & Co | Fremgangsmaade til fremstilling af et b30-threonin-insulin |
| JPS55138391A (en) * | 1979-04-13 | 1980-10-29 | Shionogi & Co Ltd | New synthetic method of peptide derivative |
| JPS55138393A (en) * | 1979-04-13 | 1980-10-29 | Shionogi & Co Ltd | Semisynthesis of insulin |
| US4343898A (en) * | 1980-02-11 | 1982-08-10 | Novo Industri A/S | Process for preparing esters of human insulin |
| DK319780A (da) * | 1980-07-24 | 1982-01-25 | Forenede Bryggerier As | Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner |
| EP0087238A1 (en) * | 1982-02-08 | 1983-08-31 | Biogen N.V. | Am improved method for preparing human insulin from non-human insulin |
-
1981
- 1981-08-10 DK DK353781A patent/DK353781A/da unknown
-
1982
- 1982-08-09 GB GB08222914A patent/GB2105342B/en not_active Expired
- 1982-08-09 BE BE6/47694A patent/BE894070A/fr not_active IP Right Cessation
- 1982-08-09 CA CA000408994A patent/CA1174973A/en not_active Expired
- 1982-08-09 NO NO822704A patent/NO157506C/no unknown
- 1982-08-09 AT AT0303582A patent/AT374683B/de active
- 1982-08-09 LU LU84327A patent/LU84327A1/de unknown
- 1982-08-09 US US06/406,571 patent/US4489159A/en not_active Expired - Lifetime
- 1982-08-09 CH CH4775/82A patent/CH661746A5/de not_active IP Right Cessation
- 1982-08-09 AU AU86974/82A patent/AU549066B2/en not_active Ceased
- 1982-08-09 FI FI822773A patent/FI79142C/fi not_active IP Right Cessation
- 1982-08-09 DE DE19823229674 patent/DE3229674A1/de active Granted
- 1982-08-09 SE SE8204627A patent/SE451073B/sv not_active IP Right Cessation
- 1982-08-09 IT IT22784/82A patent/IT1152492B/it active
- 1982-08-09 NL NLAANVRAGE8203137,A patent/NL182964C/xx not_active IP Right Cessation
- 1982-08-09 GR GR68986A patent/GR77999B/el unknown
- 1982-08-09 FR FR8213868A patent/FR2511036B1/fr not_active Expired
- 1982-08-09 ES ES514845A patent/ES514845A0/es active Granted
- 1982-08-09 IE IE1911/82A patent/IE53712B1/en not_active IP Right Cessation
- 1982-08-10 JP JP57138095A patent/JPS5836399A/ja active Granted
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