DK3513806T5 - Immunogen sammensætning - Google Patents

Immunogen sammensætning Download PDF

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Publication number
DK3513806T5
DK3513806T5 DK19159001.7T DK19159001T DK3513806T5 DK 3513806 T5 DK3513806 T5 DK 3513806T5 DK 19159001 T DK19159001 T DK 19159001T DK 3513806 T5 DK3513806 T5 DK 3513806T5
Authority
DK
Denmark
Prior art keywords
immunogenic composition
immunogenic
composition
Prior art date
Application number
DK19159001.7T
Other languages
Danish (da)
English (en)
Other versions
DK3513806T3 (da
Inventor
Dominique Boutriau
Sophie Marie Jeanne Valentine Germain
Hugues Wallemacq
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of DK3513806T3 publication Critical patent/DK3513806T3/da
Application granted granted Critical
Publication of DK3513806T5 publication Critical patent/DK3513806T5/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/08Clostridium, e.g. Clostridium tetani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
DK19159001.7T 2012-12-05 2013-12-03 Immunogen sammensætning DK3513806T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201221875 2012-12-05
EP13801540.9A EP2928489B1 (en) 2012-12-05 2013-12-03 Immunogenic composition

Publications (2)

Publication Number Publication Date
DK3513806T3 DK3513806T3 (da) 2023-02-27
DK3513806T5 true DK3513806T5 (da) 2024-09-02

Family

ID=49724573

Family Applications (2)

Application Number Title Priority Date Filing Date
DK13801540.9T DK2928489T3 (en) 2012-12-05 2013-12-03 IMMUNOGENE COMPOSITION
DK19159001.7T DK3513806T5 (da) 2012-12-05 2013-12-03 Immunogen sammensætning

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK13801540.9T DK2928489T3 (en) 2012-12-05 2013-12-03 IMMUNOGENE COMPOSITION

Country Status (22)

Country Link
US (2) US9694064B2 (OSRAM)
EP (2) EP2928489B1 (OSRAM)
JP (2) JP6290918B2 (OSRAM)
CN (2) CN104884081A (OSRAM)
AR (1) AR093712A1 (OSRAM)
AU (1) AU2013354186A1 (OSRAM)
BR (1) BR112015012841B1 (OSRAM)
CA (1) CA2893435C (OSRAM)
CY (1) CY1121560T1 (OSRAM)
DK (2) DK2928489T3 (OSRAM)
ES (2) ES2939307T3 (OSRAM)
FI (1) FI3513806T3 (OSRAM)
HR (2) HRP20230359T1 (OSRAM)
HU (2) HUE061273T2 (OSRAM)
LT (2) LT2928489T (OSRAM)
PL (2) PL2928489T3 (OSRAM)
PT (2) PT3513806T (OSRAM)
SG (1) SG11201503861UA (OSRAM)
SI (2) SI3513806T1 (OSRAM)
TR (1) TR201905272T4 (OSRAM)
WO (1) WO2014086787A1 (OSRAM)
ZA (1) ZA201503927B (OSRAM)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2201961B1 (en) * 2005-06-27 2018-01-24 GlaxoSmithKline Biologicals S.A. Immunogenic composition
HUE033342T2 (en) 2010-09-03 2017-11-28 Valneva Austria Gmbh Isolated polypeptide of the toxin a and toxin b proteins of c. difficile and uses thereof
HUE047085T2 (hu) 2011-04-22 2020-04-28 Wyeth Llc Clostridium difficile mutáns toxinjához kapcsolódó készítmények és eljárásai
BR122016023101B1 (pt) * 2012-10-21 2022-03-22 Pfizer Inc Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
DK2928489T3 (en) * 2012-12-05 2019-04-23 Glaxosmithkline Biologicals Sa IMMUNOGENE COMPOSITION
LT3160500T (lt) * 2014-06-25 2019-10-25 Glaxosmithkline Biologicals Sa Clostridium difficile imunogeninė kompozicija
DK3174553T3 (en) * 2014-07-25 2018-07-23 Biosynth Srl GLYCOCOONJUGATE VACCINES INCLUDING BASIC UNITS OF A MOLECULE CONSTRUCTION THAT EXPRESSES MULTIPLE INTEGRATED EPITOPES FOR THE FORMULATION OF A WIDE-SPECTED VACCINE AGAINST INFECTIONS BASED ON BACTEROGEN
CA2976976C (en) 2015-02-19 2023-02-28 Immune Biosolutions Inc. Clostridium difficile toxins a and/or b antigen and epitope antibody, and pharmaceutical uses thereof
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
EP3433264A4 (en) 2016-03-21 2019-08-28 Children's Medical Center Corporation COMPOSITIONS AND METHODS FOR INHIBITING WNT SIGNALING
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CA3056090A1 (en) * 2017-03-15 2018-09-20 Novavax, Inc. Methods and compositions for inducing immune responses against clostridium difficile
CN107397956A (zh) * 2017-08-08 2017-11-28 南开大学 一种铜绿假单胞菌外膜蛋白疫苗的制备方法及应用
CN112512556A (zh) 2018-01-16 2021-03-16 儿童医学中心公司 用于抑制wnt信号传导的组合物和方法
GB201804092D0 (en) * 2018-03-14 2018-04-25 Imperial Innovations Ltd Methods and compositions
US10933126B2 (en) 2018-05-03 2021-03-02 The Board Of Regents Of The University Of Oklahoma Clostridium difficile immunogenic compositions and methods of use
EP3972638A4 (en) * 2019-05-21 2023-09-13 The Regents Of The University Of California VACCINE COMPOSITION FOR CLOSTRIDIUM DIFFICILE
EP4168032A2 (en) * 2020-06-19 2023-04-26 Pfizer Inc. Immunogenic compositions against clostridioides (clostridium) difficile and methods thereof
KR20250120405A (ko) * 2022-12-13 2025-08-08 화이자 인코포레이티드 클로스트리디오이데스 (클로스트리디움) 디피실레에 대한 면역 반응을 도출하기 위한 면역원성 조성물 및 방법
WO2024160901A1 (en) 2023-02-02 2024-08-08 Glaxosmithkline Biologicals Sa Immunogenic composition

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Also Published As

Publication number Publication date
EP3513806A1 (en) 2019-07-24
BR112015012841A2 (pt) 2017-09-26
TR201905272T4 (tr) 2019-05-21
CA2893435A1 (en) 2014-06-12
US10130694B2 (en) 2018-11-20
PT3513806T (pt) 2023-03-02
SI2928489T1 (sl) 2019-05-31
LT2928489T (lt) 2019-04-10
CY1121560T1 (el) 2020-05-29
HRP20190711T1 (hr) 2019-05-31
US9694064B2 (en) 2017-07-04
CN104884081A (zh) 2015-09-02
JP6290918B2 (ja) 2018-03-07
JP2016502551A (ja) 2016-01-28
AU2013354186A1 (en) 2014-06-12
CA2893435C (en) 2024-11-12
PL3513806T3 (pl) 2023-05-15
ES2721930T3 (es) 2019-08-06
EP3513806B1 (en) 2023-01-25
SG11201503861UA (en) 2015-06-29
US20150313984A1 (en) 2015-11-05
WO2014086787A1 (en) 2014-06-12
HRP20230359T1 (hr) 2023-06-09
PL2928489T3 (pl) 2019-07-31
ES2939307T3 (es) 2023-04-20
SI3513806T1 (sl) 2023-04-28
FI3513806T3 (fi) 2023-04-26
ZA201503927B (en) 2017-11-29
BR112015012841B1 (pt) 2022-05-03
HUE043091T2 (hu) 2019-08-28
CN112807422A (zh) 2021-05-18
JP2018104446A (ja) 2018-07-05
DK3513806T3 (da) 2023-02-27
HUE061273T2 (hu) 2023-06-28
LT3513806T (lt) 2023-04-11
JP6626521B2 (ja) 2019-12-25
DK2928489T3 (en) 2019-04-23
EP2928489A1 (en) 2015-10-14
EP2928489B1 (en) 2019-02-27
US20170340719A1 (en) 2017-11-30
AR093712A1 (es) 2015-06-17
PT2928489T (pt) 2019-05-28

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