HUE043091T2 - Immunogén készítmény - Google Patents

Immunogén készítmény

Info

Publication number
HUE043091T2
HUE043091T2 HUE13801540A HUE13801540A HUE043091T2 HU E043091 T2 HUE043091 T2 HU E043091T2 HU E13801540 A HUE13801540 A HU E13801540A HU E13801540 A HUE13801540 A HU E13801540A HU E043091 T2 HUE043091 T2 HU E043091T2
Authority
HU
Hungary
Prior art keywords
immunogenic composition
immunogenic
composition
Prior art date
Application number
HUE13801540A
Other languages
English (en)
Inventor
Dominique Boutriau
Sophie Marie Jeanne Valentine Germain
Hugues Wallemacq
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of HUE043091T2 publication Critical patent/HUE043091T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/08Clostridium, e.g. Clostridium tetani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
HUE13801540A 2012-12-05 2013-12-03 Immunogén készítmény HUE043091T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB201221875 2012-12-05

Publications (1)

Publication Number Publication Date
HUE043091T2 true HUE043091T2 (hu) 2019-08-28

Family

ID=49724573

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE13801540A HUE043091T2 (hu) 2012-12-05 2013-12-03 Immunogén készítmény
HUE19159001A HUE061273T2 (hu) 2012-12-05 2013-12-03 Immunogén készítmény

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE19159001A HUE061273T2 (hu) 2012-12-05 2013-12-03 Immunogén készítmény

Country Status (22)

Country Link
US (2) US9694064B2 (hu)
EP (2) EP2928489B1 (hu)
JP (2) JP6290918B2 (hu)
CN (2) CN104884081A (hu)
AR (1) AR093712A1 (hu)
AU (1) AU2013354186A1 (hu)
BR (1) BR112015012841B1 (hu)
CA (1) CA2893435A1 (hu)
CY (1) CY1121560T1 (hu)
DK (2) DK2928489T3 (hu)
ES (2) ES2721930T3 (hu)
FI (1) FI3513806T3 (hu)
HR (2) HRP20230359T1 (hu)
HU (2) HUE043091T2 (hu)
LT (2) LT3513806T (hu)
PL (2) PL2928489T3 (hu)
PT (2) PT2928489T (hu)
SG (1) SG11201503861UA (hu)
SI (2) SI2928489T1 (hu)
TR (1) TR201905272T4 (hu)
WO (1) WO2014086787A1 (hu)
ZA (1) ZA201503927B (hu)

Families Citing this family (15)

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US9931397B2 (en) * 2005-06-27 2018-04-03 Glaxosmithkline Biologicals S.A. Immunogenic composition
RS55707B2 (sr) 2010-09-03 2022-10-31 Valneva Austria Gmbh Izolovani polipeptid toksin a i toksin b proteina c. difficile i njihova upotreba
PL3505531T3 (pl) 2011-04-22 2024-03-11 Wyeth Llc Kompozycje związane ze zmutowaną toksyną Clostridium difficile i sposoby ich wytwarzania
BR122016023101B1 (pt) 2012-10-21 2022-03-22 Pfizer Inc Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
HUE043091T2 (hu) * 2012-12-05 2019-08-28 Glaxosmithkline Biologicals Sa Immunogén készítmény
MX2016017094A (es) * 2014-06-25 2017-05-03 Glaxosmithkline Biologicals Sa Composicion inmunógena de clostridium difficile.
WO2016012587A1 (en) * 2014-07-25 2016-01-28 Biosynth S.R.L. Glycoconjugate vaccines comprising basic units of a molecular construct expressing built-in multiple epitopes for the formulation of a broad-spectrum vaccine against infections due to enteropathogenic bacteria
US10533036B2 (en) 2015-02-19 2020-01-14 Immune Biosolutions Inc Clostridium difficile toxins a and/or B antigen and epitope antibody, and pharmaceutical uses thereof
CA3014498A1 (en) 2016-03-21 2017-09-28 Children's Medical Center Corporation Compositions and methods for inhibiting wnt signaling
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
MX2019010948A (es) * 2017-03-15 2020-01-09 Novavax Inc Métodos y composiciones para inducir respuestas inmunitarias contra clostridium difficile.
CN107397956A (zh) * 2017-08-08 2017-11-28 南开大学 一种铜绿假单胞菌外膜蛋白疫苗的制备方法及应用
US10933126B2 (en) 2018-05-03 2021-03-02 The Board Of Regents Of The University Of Oklahoma Clostridium difficile immunogenic compositions and methods of use
EP4168032A2 (en) * 2020-06-19 2023-04-26 Pfizer Inc. Immunogenic compositions against clostridioides (clostridium) difficile and methods thereof
WO2024160901A1 (en) 2023-02-02 2024-08-08 Glaxosmithkline Biologicals Sa Immunogenic composition

Family Cites Families (30)

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US4866034A (en) 1982-05-26 1989-09-12 Ribi Immunochem Research Inc. Refined detoxified endotoxin
US4436727A (en) 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US4877611A (en) 1986-04-15 1989-10-31 Ribi Immunochem Research Inc. Vaccine containing tumor antigens and adjuvants
EP0362278A4 (en) 1987-06-05 1990-05-14 Us Health FACTORS OF AUTOCRINE MOTILITY IN THE DIAGNOSIS AND TREATMENT OF CANCER.
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
ES2068989T3 (es) 1989-02-04 1995-05-01 Akzo Nobel Nv Tocoles como adyuvante en vacunas.
JPH0832638B2 (ja) 1989-05-25 1996-03-29 カイロン コーポレイション サブミクロン油滴乳剤を含んで成るアジュバント製剤
UA40597C2 (uk) 1992-06-25 2001-08-15 Смітклайн Бічем Байолоджікалс С.А. Вакцинна композиція,спосіб лікування ссавців, що страждають або сприйнятливі до інфекції, спосіб лікування ссавців, що страждають на рак, спосіб одержання вакцинної композиції, композиція ад'ювантів
ES2162139T5 (es) 1993-03-23 2008-05-16 Smithkline Beecham Biologicals S.A. Composiciones de vacuna que contienen monofosforil-lipido a 3-o-desacilado.
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
NZ337543A (en) 1994-10-24 2002-06-28 Allergan Inc Composition comprising avian antitoxin against clostridial neurotoxin protein and method for producing recombinant antitoxin proteins are provided for
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
EP1024826B1 (en) 1997-10-20 2005-03-16 Acambis, Inc. Passive immunization against clostridium difficile disease
US6733760B1 (en) * 1999-04-09 2004-05-11 Techlab, Inc. Recombinant toxin A/toxin B vaccine against Clostridium difficile
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RS55707B2 (sr) * 2010-09-03 2022-10-31 Valneva Austria Gmbh Izolovani polipeptid toksin a i toksin b proteina c. difficile i njihova upotreba
HUE030823T2 (hu) 2011-05-27 2017-06-28 Glaxosmithkline Biologicals Sa Immunogén készítmény
HUE043091T2 (hu) * 2012-12-05 2019-08-28 Glaxosmithkline Biologicals Sa Immunogén készítmény

Also Published As

Publication number Publication date
US10130694B2 (en) 2018-11-20
US9694064B2 (en) 2017-07-04
PL2928489T3 (pl) 2019-07-31
AR093712A1 (es) 2015-06-17
ES2721930T3 (es) 2019-08-06
JP2016502551A (ja) 2016-01-28
SG11201503861UA (en) 2015-06-29
LT2928489T (lt) 2019-04-10
EP2928489B1 (en) 2019-02-27
PL3513806T3 (pl) 2023-05-15
ZA201503927B (en) 2017-11-29
US20170340719A1 (en) 2017-11-30
CN112807422A (zh) 2021-05-18
HRP20190711T1 (hr) 2019-05-31
JP2018104446A (ja) 2018-07-05
BR112015012841A2 (pt) 2017-09-26
DK3513806T3 (da) 2023-02-27
DK2928489T3 (en) 2019-04-23
HUE061273T2 (hu) 2023-06-28
CN104884081A (zh) 2015-09-02
AU2013354186A1 (en) 2014-06-12
HRP20230359T1 (hr) 2023-06-09
EP3513806A1 (en) 2019-07-24
BR112015012841B1 (pt) 2022-05-03
PT2928489T (pt) 2019-05-28
JP6290918B2 (ja) 2018-03-07
US20150313984A1 (en) 2015-11-05
DK3513806T5 (da) 2024-09-02
SI2928489T1 (sl) 2019-05-31
LT3513806T (lt) 2023-04-11
PT3513806T (pt) 2023-03-02
TR201905272T4 (tr) 2019-05-21
SI3513806T1 (sl) 2023-04-28
WO2014086787A1 (en) 2014-06-12
CA2893435A1 (en) 2014-06-12
CY1121560T1 (el) 2020-05-29
ES2939307T3 (es) 2023-04-20
JP6626521B2 (ja) 2019-12-25
EP3513806B1 (en) 2023-01-25
FI3513806T3 (fi) 2023-04-26
EP2928489A1 (en) 2015-10-14

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