DK3512518T3 - Buprenophinformuleringer med langvarig frigivelse - Google Patents

Buprenophinformuleringer med langvarig frigivelse Download PDF

Info

Publication number
DK3512518T3
DK3512518T3 DK17850245.6T DK17850245T DK3512518T3 DK 3512518 T3 DK3512518 T3 DK 3512518T3 DK 17850245 T DK17850245 T DK 17850245T DK 3512518 T3 DK3512518 T3 DK 3512518T3
Authority
DK
Denmark
Prior art keywords
buprenophin
sustained
formulations
release
release buprenophin
Prior art date
Application number
DK17850245.6T
Other languages
Danish (da)
English (en)
Inventor
Tong-Ho Lin
Yung-Shun Wen
Jui-Wei Liang
Original Assignee
Alar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alar Pharmaceuticals Inc filed Critical Alar Pharmaceuticals Inc
Application granted granted Critical
Publication of DK3512518T3 publication Critical patent/DK3512518T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK17850245.6T 2016-09-13 2017-09-12 Buprenophinformuleringer med langvarig frigivelse DK3512518T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662394168P 2016-09-13 2016-09-13
PCT/CN2017/101327 WO2018050043A1 (en) 2016-09-13 2017-09-12 Sustained-release buprenorphine formulations background of invention

Publications (1)

Publication Number Publication Date
DK3512518T3 true DK3512518T3 (da) 2023-01-30

Family

ID=61619029

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17850245.6T DK3512518T3 (da) 2016-09-13 2017-09-12 Buprenophinformuleringer med langvarig frigivelse

Country Status (31)

Country Link
US (1) US10744132B2 (https=)
EP (1) EP3512518B1 (https=)
JP (1) JP6929367B2 (https=)
KR (1) KR102244500B1 (https=)
CN (1) CN109789137B (https=)
AR (1) AR110468A1 (https=)
AU (1) AU2017325910B2 (https=)
BR (1) BR112019004923A2 (https=)
CA (1) CA3033046C (https=)
CL (1) CL2019000624A1 (https=)
CO (1) CO2019003632A2 (https=)
DK (1) DK3512518T3 (https=)
ES (1) ES2934721T3 (https=)
FI (1) FI3512518T3 (https=)
HR (1) HRP20230062T8 (https=)
HU (1) HUE060906T2 (https=)
LT (1) LT3512518T (https=)
MX (1) MX374304B (https=)
MY (1) MY196269A (https=)
PE (1) PE20190707A1 (https=)
PH (1) PH12019500466A1 (https=)
PL (1) PL3512518T3 (https=)
PT (1) PT3512518T (https=)
RS (1) RS63894B1 (https=)
RU (1) RU2747306C2 (https=)
SG (1) SG11201901294QA (https=)
SI (1) SI3512518T1 (https=)
SM (1) SMT202300006T1 (https=)
TW (1) TWI743193B (https=)
WO (1) WO2018050043A1 (https=)
ZA (1) ZA201900890B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1057075C (zh) * 1997-09-10 2000-10-04 中国石油化工总公司 低碳烯烃直接水合连续生产低碳醇的方法
BR112020016576A2 (pt) 2018-05-11 2020-12-15 Alar Pharmaceuticals Inc. Formulações injetáveis de ação prolongada e formas cristalinas de derivados de buprenorfina
KR102898979B1 (ko) * 2018-12-27 2025-12-10 에일러 파마슈티컬스 아이엔씨. 주사가능한 날트렉손 서방형 약학 제제
EP3936112A1 (en) * 2020-07-07 2022-01-12 Occlugel Hydrophilic degradable microspheres for delivering buprenorphine
IL308211A (en) * 2021-05-05 2024-01-01 Lyndra Therapeutics Inc Gastric residence systems comprising methadone

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO121631B1 (ro) 1999-08-27 2008-01-30 Southern Research Institute Compoziţie cu buprenorfină şi utilizarea acesteia pentru reducerea consumului de heroină şi/sau alcool
DE60329515D1 (de) 2002-10-25 2009-11-12 Euro Celtique Sa Analoga und prodrugs von buprenorphin
CN1263760C (zh) * 2002-11-12 2006-07-12 财团法人奇美医院 新颖的丁丙诺啡酯衍生物及其制备方法,以及长效作用镇痛药学组合物
TWI226830B (en) * 2002-11-12 2005-01-21 Chi Mei Foundation Medical Ct Novel ester derivatives of buprenorphine and their preparation processes, and long acting analgesic pharmaceutical compositions
DE60224288T2 (de) 2002-11-25 2009-04-16 Chi Mei Foundation Medical Center Buprenorphinesterderivate, Verfahren zu ihrer Herstellung, und langwirksame analgetische Arzneimittel
WO2005117830A1 (en) 2004-06-04 2005-12-15 Camurus Ab Liquid depot formulations
RU2008124805A (ru) * 2005-11-21 2009-12-27 Шеринг-Плоу Лтд. (CH) Фармацевтические композиции, содержащие бупренорфин
GB0606124D0 (en) 2006-03-28 2006-05-03 Reckitt Benckiser Healthcare Buprenorphine derivatives and uses thereof
ES2549115T3 (es) * 2006-09-22 2015-10-23 Zynerba Pharmaceuticals, Inc. Profármacos de buprenorfina administrables por vía transdérmica y composiciones resistentes al consumo excesivo de los mismos
US20090181068A1 (en) * 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
GB2481017B (en) 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
GB2481018B (en) 2010-06-08 2015-03-18 Rb Pharmaceuticals Ltd Injectable flowable composition comprising buprenorphine
FR2975912B1 (fr) 2011-05-30 2013-06-14 Flamel Tech Sa Composition a liberation controlee de buprenorphine
US9393211B2 (en) 2013-03-15 2016-07-19 Oakwood Laboratories LLC High drug load buprenorphine microspheres and method of producing same
GB201404139D0 (en) * 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
GB201419091D0 (en) * 2014-10-27 2014-12-10 Camurus Ab Formulations

Also Published As

Publication number Publication date
US10744132B2 (en) 2020-08-18
FI3512518T3 (fi) 2023-01-31
PE20190707A1 (es) 2019-05-17
RU2019102895A (ru) 2020-08-03
TWI743193B (zh) 2021-10-21
ZA201900890B (en) 2021-08-25
WO2018050043A1 (en) 2018-03-22
CN109789137B (zh) 2023-01-13
PH12019500466A1 (en) 2020-01-20
SMT202300006T1 (it) 2023-03-17
AR110468A1 (es) 2019-04-03
LT3512518T (lt) 2023-02-10
TW201821077A (zh) 2018-06-16
AU2017325910A1 (en) 2019-02-21
MY196269A (en) 2023-03-24
ES2934721T3 (es) 2023-02-24
EP3512518A1 (en) 2019-07-24
MX374304B (es) 2025-03-06
KR20190052021A (ko) 2019-05-15
BR112019004923A2 (pt) 2019-06-04
KR102244500B1 (ko) 2021-04-26
NZ750367A (en) 2021-01-29
RS63894B1 (sr) 2023-02-28
PL3512518T3 (pl) 2023-03-27
SG11201901294QA (en) 2019-03-28
JP6929367B2 (ja) 2021-09-01
RU2747306C2 (ru) 2021-05-04
MX2019002675A (es) 2019-08-01
AU2017325910B2 (en) 2020-08-27
RU2019102895A3 (https=) 2020-12-01
US20190142823A1 (en) 2019-05-16
EP3512518B1 (en) 2022-10-26
SI3512518T1 (sl) 2023-04-28
PT3512518T (pt) 2023-01-27
HUE060906T2 (hu) 2023-04-28
CN109789137A (zh) 2019-05-21
CO2019003632A2 (es) 2019-06-28
CL2019000624A1 (es) 2019-06-14
CA3033046A1 (en) 2018-03-22
JP2019529543A (ja) 2019-10-17
EP3512518A4 (en) 2020-06-03
HRP20230062T8 (hr) 2023-04-14
CA3033046C (en) 2021-09-07
HRP20230062T1 (hr) 2023-03-31

Similar Documents

Publication Publication Date Title
IL268697A (en) Formulations
DK3688162T3 (da) Formuleringer
MA50657A (fr) Formulations de niraparib
EP3509581A4 (en) FORMULATIONS OF (R
DK3529248T3 (da) Farmaceutiske sammensætninger
IL262335A (en) Stable nimopidine parenteral formulation
SI4070787T1 (sl) Farmacevtske formulacije
DK3529240T3 (da) Farmaceutiske forbindelser
EP3364945C0 (en) SOLID FORMULATION
LT3464336T (lt) Junginiai
EP3541200C0 (en) POWDERED FORMULATIONS
EP3960158C0 (en) AMLODIPINE FORMULATIONS
EP3454847A4 (en) IMPROVED DRUG FORMULATIONS
HUE063178T2 (hu) Kopanlizib formulációi
DK3512518T3 (da) Buprenophinformuleringer med langvarig frigivelse
DK3280447T3 (da) Farmaceutiske formuleringer
IL272167A (en) Hemopexin formulations
EP3512503A4 (en) Liposomal formulations
EP3444345A4 (en) MicroRNA-143 DERIVATIVE
DE112017000734A5 (de) Glycolsensor
DE112017006386A5 (de) Schraubarbeitszylinder
DK3323708T3 (da) Bovfender
PT3678644T (pt) Formulações de copanlisib
DE112017005767A5 (de) Nasslaufende lamellenkupplung
DK3412667T3 (da) Cokrystal