PT3512518T - Formulações de buprenorfina de libertação prolongada - Google Patents

Formulações de buprenorfina de libertação prolongada

Info

Publication number
PT3512518T
PT3512518T PT178502456T PT17850245T PT3512518T PT 3512518 T PT3512518 T PT 3512518T PT 178502456 T PT178502456 T PT 178502456T PT 17850245 T PT17850245 T PT 17850245T PT 3512518 T PT3512518 T PT 3512518T
Authority
PT
Portugal
Prior art keywords
sustained
release buprenorphine
formulations background
buprenorphine formulations
background
Prior art date
Application number
PT178502456T
Other languages
English (en)
Original Assignee
Alar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alar Pharmaceuticals Inc filed Critical Alar Pharmaceuticals Inc
Publication of PT3512518T publication Critical patent/PT3512518T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT178502456T 2016-09-13 2017-09-12 Formulações de buprenorfina de libertação prolongada PT3512518T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662394168P 2016-09-13 2016-09-13

Publications (1)

Publication Number Publication Date
PT3512518T true PT3512518T (pt) 2023-01-27

Family

ID=61619029

Family Applications (1)

Application Number Title Priority Date Filing Date
PT178502456T PT3512518T (pt) 2016-09-13 2017-09-12 Formulações de buprenorfina de libertação prolongada

Country Status (30)

Country Link
US (1) US10744132B2 (pt)
EP (1) EP3512518B1 (pt)
JP (1) JP6929367B2 (pt)
KR (1) KR102244500B1 (pt)
CN (1) CN109789137B (pt)
AR (1) AR110468A1 (pt)
AU (1) AU2017325910B2 (pt)
BR (1) BR112019004923A2 (pt)
CA (1) CA3033046C (pt)
CL (1) CL2019000624A1 (pt)
CO (1) CO2019003632A2 (pt)
DK (1) DK3512518T3 (pt)
ES (1) ES2934721T3 (pt)
FI (1) FI3512518T3 (pt)
HR (1) HRP20230062T8 (pt)
HU (1) HUE060906T2 (pt)
LT (1) LT3512518T (pt)
MX (1) MX2019002675A (pt)
MY (1) MY196269A (pt)
PE (1) PE20190707A1 (pt)
PH (1) PH12019500466A1 (pt)
PL (1) PL3512518T3 (pt)
PT (1) PT3512518T (pt)
RS (1) RS63894B1 (pt)
RU (1) RU2747306C2 (pt)
SG (1) SG11201901294QA (pt)
SI (1) SI3512518T1 (pt)
TW (1) TWI743193B (pt)
WO (1) WO2018050043A1 (pt)
ZA (1) ZA201900890B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1057075C (zh) * 1997-09-10 2000-10-04 中国石油化工总公司 低碳烯烃直接水合连续生产低碳醇的方法
CN111954672B (zh) * 2018-05-11 2023-09-01 昱展新药生技股份有限公司 丁丙诺啡衍生物的长效注射制剂及结晶形式
AU2019416507A1 (en) * 2018-12-27 2021-06-03 Alar Pharmaceuticals Inc. Naltrexone injectable sustained release formulation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001015699A1 (en) 1999-08-27 2001-03-08 Southern Research Institute Injectable buprenorphine microparticle compositions and their use
ATE444296T1 (de) 2002-10-25 2009-10-15 Euro Celtique Sa Analoga und prodrugs von buprenorphin
TWI226830B (en) * 2002-11-12 2005-01-21 Chi Mei Foundation Medical Ct Novel ester derivatives of buprenorphine and their preparation processes, and long acting analgesic pharmaceutical compositions
CN1263760C (zh) * 2002-11-12 2006-07-12 财团法人奇美医院 新颖的丁丙诺啡酯衍生物及其制备方法,以及长效作用镇痛药学组合物
EP1422230B1 (en) * 2002-11-25 2007-12-26 Chi Mei Foundation Medical Center Novel ester derivatives of buprenorphine and their preparation processes, and long acting analgestic pharmaceutical compositions
ES2309766T3 (es) 2004-06-04 2008-12-16 Camurus Ab Formulaciones liquidas de liberacion lenta.
KR20080071185A (ko) * 2005-11-21 2008-08-01 쉐링-프라우 리미티드 부프레노르핀을 포함하는 약제학적 조성물
GB0606124D0 (en) * 2006-03-28 2006-05-03 Reckitt Benckiser Healthcare Buprenorphine derivatives and uses thereof
WO2008036980A1 (en) * 2006-09-22 2008-03-27 Alltranz Inc. Transdermally deliverable buprenorphine prodrugs and abuse-resistant compositions thereof
US20090181068A1 (en) * 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
GB2513060B (en) * 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
GB2513267B (en) 2010-06-08 2015-03-18 Rb Pharmaceuticals Ltd Injectable flowable composition comprising buprenorphine
FR2975912B1 (fr) * 2011-05-30 2013-06-14 Flamel Tech Sa Composition a liberation controlee de buprenorphine
US9393211B2 (en) 2013-03-15 2016-07-19 Oakwood Laboratories LLC High drug load buprenorphine microspheres and method of producing same
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
GB201419091D0 (en) * 2014-10-27 2014-12-10 Camurus Ab Formulations

Also Published As

Publication number Publication date
JP2019529543A (ja) 2019-10-17
KR102244500B1 (ko) 2021-04-26
HRP20230062T8 (hr) 2023-04-14
EP3512518B1 (en) 2022-10-26
ES2934721T3 (es) 2023-02-24
CA3033046C (en) 2021-09-07
KR20190052021A (ko) 2019-05-15
BR112019004923A2 (pt) 2019-06-04
TW201821077A (zh) 2018-06-16
WO2018050043A1 (en) 2018-03-22
MX2019002675A (es) 2019-08-01
CL2019000624A1 (es) 2019-06-14
NZ750367A (en) 2021-01-29
MY196269A (en) 2023-03-24
JP6929367B2 (ja) 2021-09-01
FI3512518T3 (fi) 2023-01-31
CA3033046A1 (en) 2018-03-22
US20190142823A1 (en) 2019-05-16
EP3512518A4 (en) 2020-06-03
PH12019500466A1 (en) 2020-01-20
SI3512518T1 (sl) 2023-04-28
HRP20230062T1 (hr) 2023-03-31
HUE060906T2 (hu) 2023-04-28
DK3512518T3 (da) 2023-01-30
CN109789137A (zh) 2019-05-21
AR110468A1 (es) 2019-04-03
RU2019102895A3 (pt) 2020-12-01
LT3512518T (lt) 2023-02-10
ZA201900890B (en) 2021-08-25
RU2019102895A (ru) 2020-08-03
TWI743193B (zh) 2021-10-21
CO2019003632A2 (es) 2019-06-28
PE20190707A1 (es) 2019-05-17
SG11201901294QA (en) 2019-03-28
AU2017325910B2 (en) 2020-08-27
RS63894B1 (sr) 2023-02-28
EP3512518A1 (en) 2019-07-24
RU2747306C2 (ru) 2021-05-04
CN109789137B (zh) 2023-01-13
PL3512518T3 (pl) 2023-03-27
AU2017325910A1 (en) 2019-02-21
US10744132B2 (en) 2020-08-18

Similar Documents

Publication Publication Date Title
IL269409A (en) Combinations of chk1- and wee1 - inhibitors
IL265628A (en) Solid state forms of valbenazine
IL292245A (en) Polymorphic forms of rad1901–2hcl
FI3943070T3 (fi) Pitkävaikutteisia bedakiliiniformulaatioita
IL272697A (en) A polymorphic form of TG02
ZA201808524B (en) Methods of affecting separation
ZA201706282B (en) Solid forms of menaquinols
EP3894768C0 (en) METHOD FOR CRYOHARDENING
IL263673A (en) Solid state forms of spiro-oxindole compounds
IL272857A (en) Cofanalisib formulations
ZA201900890B (en) Sustained-release buprenorphine formulations
GB201609314D0 (en) Methods of forming compounds
ZA201808387B (en) Improved process for the preparation of carbamates
IL276107A (en) Crystalline forms of psoorstam
PT3678644T (pt) Formulações de copanlisib
IL263363A (en) Polymorph of nintedanib
GB201721386D0 (en) Chrondogy of time-wave
GB201701233D0 (en) Field of invention
GB201611620D0 (en) Novel formulations of valsartan
GB201611600D0 (en) Novel formulations of valsartan
GB201707716D0 (en) Point of interest location specification
GB201621867D0 (en) Novel formulations of aprepitant
GB201611619D0 (en) Novel formulations of losartan
GB201611623D0 (en) Novel formulations of losartan
GB201600282D0 (en) Method of manufacture