DK3468568T3 - Ekstracellulære vesikler der er afledt af humantrombo-cytlysat, til anvendelse i medicin - Google Patents

Ekstracellulære vesikler der er afledt af humantrombo-cytlysat, til anvendelse i medicin Download PDF

Info

Publication number
DK3468568T3
DK3468568T3 DK17727907.2T DK17727907T DK3468568T3 DK 3468568 T3 DK3468568 T3 DK 3468568T3 DK 17727907 T DK17727907 T DK 17727907T DK 3468568 T3 DK3468568 T3 DK 3468568T3
Authority
DK
Denmark
Prior art keywords
cytlysate
extra
medicine
vesicles derived
cellular vesicles
Prior art date
Application number
DK17727907.2T
Other languages
English (en)
Inventor
Miroschedji Kyra Natalia Matahari De
Original Assignee
Lysatpharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56112904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3468568(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lysatpharma Gmbh filed Critical Lysatpharma Gmbh
Application granted granted Critical
Publication of DK3468568T3 publication Critical patent/DK3468568T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DK17727907.2T 2016-06-08 2017-06-07 Ekstracellulære vesikler der er afledt af humantrombo-cytlysat, til anvendelse i medicin DK3468568T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16173465.2A EP3254684B1 (en) 2016-06-08 2016-06-08 Human platelet lysate or fraction enriched in human platelet-derived extracellular vesicles, for use in medicine
PCT/EP2017/063868 WO2017211906A1 (en) 2016-06-08 2017-06-07 Human platelet lysate derived extracellular vesicles for use in medicine

Publications (1)

Publication Number Publication Date
DK3468568T3 true DK3468568T3 (da) 2020-12-07

Family

ID=56112904

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17727907.2T DK3468568T3 (da) 2016-06-08 2017-06-07 Ekstracellulære vesikler der er afledt af humantrombo-cytlysat, til anvendelse i medicin

Country Status (19)

Country Link
US (2) US20190290696A1 (da)
EP (2) EP3254684B1 (da)
JP (2) JP7122976B2 (da)
KR (3) KR20190017896A (da)
CN (2) CN115710574A (da)
AU (1) AU2017276712B2 (da)
BR (1) BR112018075295A2 (da)
CA (1) CA3026004A1 (da)
DK (1) DK3468568T3 (da)
ES (1) ES2832727T3 (da)
HU (1) HUE051792T2 (da)
IL (1) IL263296B (da)
MX (1) MX2018015123A (da)
PL (1) PL3468568T3 (da)
PT (1) PT3468568T (da)
RU (1) RU2735139C2 (da)
SG (1) SG11201810117WA (da)
WO (1) WO2017211906A1 (da)
ZA (1) ZA201807760B (da)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107073090A (zh) 2014-04-30 2017-08-18 哈佛学院董事会 结合的疫苗装置和杀死癌细胞的方法
CN109072197A (zh) 2016-02-06 2018-12-21 哈佛学院校长同事会 重塑造血巢以重建免疫
TWI744300B (zh) * 2016-03-23 2021-11-01 里爾中央醫學中心 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途
CN109789092A (zh) 2016-07-13 2019-05-21 哈佛学院院长等 抗原呈递细胞模拟支架及其制备和使用方法
CN108715834B (zh) * 2018-06-01 2021-09-14 天晴干细胞股份有限公司 一种富含cd41+、cd81+微囊的血小板裂解液制备方法
US20220118109A1 (en) * 2018-12-20 2022-04-21 Ohio State Innovation Foundation Compositions and methods for reprogramming diseased musculoskeletal cells
TWI722400B (zh) * 2019-03-18 2021-03-21 佛教慈濟醫療財團法人 間質幹細胞之胞外泌體及其用途
CN110090310B (zh) * 2019-04-01 2021-08-10 东南大学 一种血小板膜自组装纳米气泡及其制备方法和应用
US20220206000A1 (en) * 2019-04-15 2022-06-30 Mycomed Technologies Llc Methods and compositions using extracellular vesicles for the detection of disease and disorders
WO2021016368A1 (en) * 2019-07-22 2021-01-28 Erivan Bio, Llc Topical exosome compositions and associated methods
CN110585243A (zh) * 2019-08-12 2019-12-20 丰泽康生物医药（深圳）有限公司 用于治疗糖皮质激素依赖性皮炎的多潜能细胞活性物与富血小板血浆复合物及制法和应用
CN110339180B (zh) * 2019-08-12 2020-10-09 苏州大学 一种抗炎靶向递送系统及其制备方法
CN110499287B (zh) * 2019-08-30 2021-07-23 博雅干细胞科技有限公司 简易制备胎盘间充质干细胞外泌体的方法
US11951134B2 (en) 2019-09-30 2024-04-09 North Carolina State University Cationic platelet lysate compositions and related methods
EP4125947A4 (en) * 2020-03-27 2024-06-12 Platelet Biogenesis, Inc. NEW ANUCLEATED CELLS FOR THE TREATMENT OF DISEASES
US20210299180A1 (en) * 2020-03-27 2021-09-30 Platelet Biogenesis, Inc. Novel anucleated cells and uses thereof
KR102384368B1 (ko) 2020-06-18 2022-04-07 경북대학교 산학협력단 섬유아세포 유래 세포외 소포체를 유효성분으로 함유하는 피부 및 점막 창상 치료용 조성물
KR102209937B1 (ko) * 2020-06-22 2021-02-01 주식회사 엑소코바이오 생산성 향상 및 생리활성 강화를 위한 엑소좀의 생산방법 및 이의 응용
WO2022099093A1 (en) * 2020-11-06 2022-05-12 President And Fellows Of Harvard College Scaffolds for enhancing neutrophils and uses thereof
CN113332312B (zh) * 2021-02-01 2023-02-24 浙江大学医学院附属邵逸夫医院 一种基于物理整粒的自成形血小板纳米囊泡及其制备方法
CN115029309A (zh) * 2021-03-05 2022-09-09 杭州市萧山区中医院 富血小板血浆来源性外泌体的分离方法及其应用
JP7025070B1 (ja) 2021-05-14 2022-02-24 セルソース株式会社 血液由来成長因子含有組成物及びその調製方法
DE102021124752A1 (de) * 2021-09-24 2023-03-30 Ad Lentus GmbH Autologes Therapeutikum und Verfahren zur Herstellung desselben
WO2023079655A1 (ja) * 2021-11-04 2023-05-11 株式会社リバティソリューション エクソソーム抽出方法
US20230277588A1 (en) * 2021-12-08 2023-09-07 Organicell Regenerative Medicine, Inc. Compositions and methods for treating pain with extracellular vesicles
WO2023150085A1 (en) * 2022-02-01 2023-08-10 Mitrix Bio, Inc. Platelet-derived mitochondria-containing extracellular vesicles for use in the treatment of ocular disorders
WO2023164134A1 (en) * 2022-02-24 2023-08-31 Mayo Foundation For Medical Education And Research Compositions and methods for modulating the immune system
KR102674407B1 (ko) * 2022-02-25 2024-06-12 ㈜클리니크후즈후 혈소판 및 혈액유래 줄기세포를 포함한 혈액유래 엑소좀 제조방법과 이를 통해 제조된 엑소좀
CN114306384B (zh) * 2022-03-08 2022-05-31 北京大学口腔医学院 一种人血小板凋亡微囊泡的应用
WO2023219915A1 (en) * 2022-05-09 2023-11-16 Mitrix Bio, Inc. Platelet-derived extracellular vessicles for treatment of cardiogenic shock and sepsis
TW202346572A (zh) * 2022-05-16 2023-12-01 台灣粒線體應用技術股份有限公司 用於減緩口腔損傷的組合物、其用途及其製備方法
WO2024077117A1 (en) * 2022-10-06 2024-04-11 Capricor, Inc. Method for making vesicles
CN115463154A (zh) * 2022-10-21 2022-12-13 上海君益禾生物医学科技有限公司 一种血小板裂解液和外泌体复合凝胶的制备方法及应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1313151C (zh) * 2002-11-04 2007-05-02 杭州浙大康泰生物技术有限公司 一种新型高效非细胞性疫苗的制备及其用途
EP1773381A4 (en) 2004-07-01 2008-07-02 Univ Pittburgh Of The Commonwe EXOSOMES IMMUNOSUPPRESSANTS
IT1392897B1 (it) 2008-07-18 2012-04-02 Fond Ircss Ca' Granda - Ospedale Maggiore Policlinico Frazione piastrinica derivante da sangue placentare
WO2010064267A1 (en) * 2008-12-05 2010-06-10 Universita' Degli Studi Di Pavia Platelets lysate and bioadesive compositions thereof for the treatment of mucositis
ES2402144T3 (es) * 2010-05-25 2013-04-29 Gwowei Technology Co., Ltd. Lisado plaquetario inactivado que contiene factores de crecimiento empobrecido en PDGF y VEGF y su procedimiento de preparación
EP2603592A2 (en) 2010-08-13 2013-06-19 The University Court of the University of Glasgow Therapeutic uses of microvesicles and related micrornas
SG2014010706A (en) 2010-10-18 2014-05-29 Agency Science Tech & Res Method and composition
IL210162A0 (en) * 2010-12-21 2011-03-31 Omrix Biopharmaceuticals Viral inactivated platelet extract, use and preparation thereof
CA2840568C (en) 2011-06-27 2021-05-04 Emory University Compositions, uses, and preparation of platelet lysates
CN104159569A (zh) 2011-11-23 2014-11-19 细胞治疗有限公司 血小板裂解物凝胶
EP2687219A1 (en) 2012-07-18 2014-01-22 Universität Duisburg-Essen Use of preparations comprising exosomes derived from mesenchymal stem cells (MSCs) in the prevention and therapy of inflammatory conditions
CN104726410B (zh) * 2013-12-23 2019-09-17 浙江大学 一种具有免疫抑制功能的外排体及其应用
EP3267965A4 (en) 2015-03-11 2018-11-14 Atta Behfar Exosome delivery technology

Also Published As

Publication number Publication date
CA3026004A1 (en) 2017-12-14
PT3468568T (pt) 2020-11-30
BR112018075295A2 (pt) 2019-07-02
US20220000931A1 (en) 2022-01-06
RU2018141006A3 (da) 2020-07-10
HUE051792T2 (hu) 2021-03-29
US20190290696A1 (en) 2019-09-26
PL3468568T3 (pl) 2021-05-04
AU2017276712B2 (en) 2020-03-12
NZ748679A (en) 2021-03-26
EP3254684B1 (en) 2019-10-23
ES2832727T3 (es) 2021-06-11
JP2022116227A (ja) 2022-08-09
MX2018015123A (es) 2019-10-15
JP2019517488A (ja) 2019-06-24
KR20190017896A (ko) 2019-02-20
EP3254684A1 (en) 2017-12-13
IL263296B (en) 2021-08-31
KR20220136461A (ko) 2022-10-07
CN109310712A (zh) 2019-02-05
EP3468568A1 (en) 2019-04-17
RU2018141006A (ru) 2020-07-10
EP3468568B1 (en) 2020-09-02
SG11201810117WA (en) 2018-12-28
RU2735139C2 (ru) 2020-10-28
JP7122976B2 (ja) 2022-08-22
KR20210047983A (ko) 2021-04-30
WO2017211906A1 (en) 2017-12-14
CN115710574A (zh) 2023-02-24
ZA201807760B (en) 2020-05-27
AU2017276712A1 (en) 2018-12-13
IL263296A (en) 2018-12-31

Similar Documents

Publication Publication Date Title
DK3468568T3 (da) Ekstracellulære vesikler der er afledt af humantrombo-cytlysat, til anvendelse i medicin
DK3505519T3 (da) Pyridinamin-substituerede heterotricyclo-forbindelser, fremstilling deraf og anvendelse i medicin
DK3463248T3 (da) Anordnnger til anvendelse af lægemiddelanordninger
DK3692857T3 (da) Indretning til levering af hudplejesammensætning
DK3134151T3 (da) Sprøjte med rullemembran
DK3356313T3 (da) 2-perfluorhexyloktan til oftalmisk indgivelse
DK3162402T3 (da) Næsespraydyse til anvendelse i medicinsk sprøjte
DK3125883T3 (da) Indolderivater til anvendelse i medicin
DK3139986T3 (da) System til administration af terapeutisk gas
CL2016002569A1 (es) Anticuerpos, composiciones farmacéuticas y usos de los mismos
BR112016018062A2 (pt) compostos terapêuticos, composição farmacêutica e usos
DK3380154T3 (da) Anordning til injektion af lægemidler
DK3882250T3 (da) Tetrahydropyranyl-amino-pyrrolopyrimidinon til anvendelse i behandling af btk-medierede forstyrrelser
DK3237045T3 (da) Indretning til indgivelse af lægemidler
DK3234107T3 (da) B-celler til in vivo-levering af terapeutiske midler
DK3193978T3 (da) Lægemiddelinjektor af hudplastertypen til voluminøs bolus med medikamentforvarmning
DK3171700T3 (da) Infusionsanlæg
DK3094322T3 (da) Administration af tasimelteon i fastende tilstand
DK3554534T3 (da) Farmaceutisk sammensætning omfattende insulin
DK3097085T3 (da) Benzoxazinonderivater til behandling af hudsygdomme
DK3337353T3 (da) Stol
DK3253208T3 (da) Kombinationsterapier til anvendelse i behandlingen af brystcancer
DK3164123T3 (da) Hidtil ukendte anvendelser af benzylidenguanidinderivater til behandling af proteopatier
DK3125874T3 (da) Et terapeutisk middel til anvendelse i behandlingen af infektioner
DK3326637T3 (da) Anvendelse af mangostanskalekstrakt til fremstilling af en medicin til behandling af hudlidelser