DK3436469T3 - Nukleinsyrestabiliseringsreagens, kits og fremgangsmåder til anvendelse deraf - Google Patents
Nukleinsyrestabiliseringsreagens, kits og fremgangsmåder til anvendelse deraf Download PDFInfo
- Publication number
- DK3436469T3 DK3436469T3 DK17776666.4T DK17776666T DK3436469T3 DK 3436469 T3 DK3436469 T3 DK 3436469T3 DK 17776666 T DK17776666 T DK 17776666T DK 3436469 T3 DK3436469 T3 DK 3436469T3
- Authority
- DK
- Denmark
- Prior art keywords
- kits
- methods
- nucleic acid
- acid stabilization
- stabilization reagents
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 230000006641 stabilisation Effects 0.000 title 1
- 238000011105 stabilization Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0645—Macrophages, e.g. Kuepfer cells in the liver; Monocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0646—Natural killers cells [NK], NKT cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/101—Temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/125—Specific component of sample, medium or buffer
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662316514P | 2016-03-31 | 2016-03-31 | |
PCT/US2017/025065 WO2017173105A1 (en) | 2016-03-31 | 2017-03-30 | Nucleic acid stabilization reagent, kits, and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3436469T3 true DK3436469T3 (da) | 2022-03-21 |
Family
ID=59966482
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK17776666.4T DK3436469T3 (da) | 2016-03-31 | 2017-03-30 | Nukleinsyrestabiliseringsreagens, kits og fremgangsmåder til anvendelse deraf |
Country Status (11)
Country | Link |
---|---|
US (1) | US20190085375A1 (da) |
EP (2) | EP4043475B1 (da) |
JP (2) | JP7019590B2 (da) |
KR (2) | KR102451535B1 (da) |
CN (2) | CN109311930B (da) |
AU (1) | AU2017239666B2 (da) |
CA (1) | CA3020728A1 (da) |
DK (1) | DK3436469T3 (da) |
IL (1) | IL262019A (da) |
SG (1) | SG11201808573YA (da) |
WO (1) | WO2017173105A1 (da) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018111765A1 (en) | 2016-12-12 | 2018-06-21 | xCella Biosciences, Inc. | Methods and systems for screening using microcapillary arrays |
JP7227162B2 (ja) | 2017-06-06 | 2023-02-21 | ザイマージェン インコーポレイテッド | 真菌株を改良するためのhtpゲノム操作プラットフォーム |
WO2019133874A1 (en) * | 2017-12-31 | 2019-07-04 | Berkeley Lights, Inc. | General functional assay |
WO2019236848A1 (en) | 2018-06-06 | 2019-12-12 | Zymergen Inc. | Manipulation of genes involved in signal transduction to control fungal morphology during fermentation and production |
CN116174068A (zh) | 2019-04-30 | 2023-05-30 | 伯克利之光生命科技公司 | 用于包封和测定细胞的方法 |
WO2021030271A2 (en) | 2019-08-09 | 2021-02-18 | Nutcracker Therapeutics, Inc. | Methods and apparatuses for manufacturing for removing material from a therapeutic composition |
GB2604481A (en) | 2019-10-10 | 2022-09-07 | 1859 Inc | Methods and systems for microfluidic screening |
US11479779B2 (en) | 2020-07-31 | 2022-10-25 | Zymergen Inc. | Systems and methods for high-throughput automated strain generation for non-sporulating fungi |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
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US6204375B1 (en) * | 1998-07-31 | 2001-03-20 | Ambion, Inc. | Methods and reagents for preserving RNA in cell and tissue samples |
GB9828709D0 (en) | 1998-12-24 | 1999-02-17 | Novartis Ag | Assay |
US6294063B1 (en) | 1999-02-12 | 2001-09-25 | Board Of Regents, The University Of Texas System | Method and apparatus for programmable fluidic processing |
US6942776B2 (en) | 1999-05-18 | 2005-09-13 | Silicon Biosystems S.R.L. | Method and apparatus for the manipulation of particles by means of dielectrophoresis |
JP2003513733A (ja) | 1999-11-17 | 2003-04-15 | グラクソ グループ リミテッド | 赤外線サーモグラフィー |
PT1326963E (pt) * | 2000-10-17 | 2008-08-29 | Zeptometrix Corp | Microorganismos tornados não patogénicos |
WO2002056030A2 (en) * | 2000-11-08 | 2002-07-18 | Becton Dickinson Co | Method and device for collecting and stabilizing a biological sample |
US20020197637A1 (en) * | 2001-06-02 | 2002-12-26 | Willson Richard C. | Process and compositions for protection of nucleic acids |
US6958132B2 (en) | 2002-05-31 | 2005-10-25 | The Regents Of The University Of California | Systems and methods for optical actuation of microfluidics based on opto-electrowetting |
US7977049B2 (en) | 2002-08-09 | 2011-07-12 | President And Fellows Of Harvard College | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
JP4472634B2 (ja) | 2003-07-10 | 2010-06-02 | ユニヴェルシテ リブル ドゥ ブリュッセル | 生物学的試料を試剤でパルスし、こうしてパルスされた試料を安定化するための装置、キット及び方法 |
US20060099567A1 (en) * | 2004-04-08 | 2006-05-11 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
WO2005100541A2 (en) | 2004-04-12 | 2005-10-27 | The Regents Of The University Of California | Optoelectronic tweezers for microparticle and cell manipulation |
WO2008091848A2 (en) | 2007-01-22 | 2008-07-31 | Advanced Liquid Logic, Inc. | Surface assisted fluid loading and droplet dispensing |
WO2008119066A1 (en) | 2007-03-28 | 2008-10-02 | The Regents Of The University Of California | Single-sided lateral-field and phototransistor-based optoelectronic tweezers |
CN102124126A (zh) | 2007-10-26 | 2011-07-13 | 生命技术公司 | 使用非随机引物的cdna合成 |
WO2009114185A2 (en) | 2008-03-12 | 2009-09-17 | The Rockefeller University | Methods and compositions for translational profiling and molecular phenotyping |
FR2952072B1 (fr) | 2009-11-05 | 2013-09-27 | Pf Medicament | Procede de production de triptolide |
US9533306B2 (en) | 2010-08-02 | 2017-01-03 | The Regents Of The University Of California | Single sided continuous optoelectrowetting (SCEOW) device for droplet manipulation with light patterns |
US9121058B2 (en) * | 2010-08-20 | 2015-09-01 | Integenx Inc. | Linear valve arrays |
US9051563B2 (en) * | 2011-01-14 | 2015-06-09 | Zymo Research Corporation | Nucleic acid purification |
US9227200B2 (en) | 2011-06-03 | 2016-01-05 | The Regents Of The University Of California | Microfluidic devices with flexible optically transparent electrodes |
US9857333B2 (en) | 2012-10-31 | 2018-01-02 | Berkeley Lights, Inc. | Pens for biological micro-objects |
US9403172B2 (en) | 2012-11-08 | 2016-08-02 | Berkeley Lights, Inc. | Circuit based optoelectronic tweezers |
JP2016509484A (ja) | 2013-02-08 | 2016-03-31 | ヨーロピアン モレキュラー バイオロジー ラボラトリーEuropean Molecular Biology Laboratory | 改良されたバキュロウイルス発現システムおよびその製造方法 |
EP2976426A1 (en) * | 2013-03-18 | 2016-01-27 | Qiagen GmbH | Stabilization and isolation of extracellular nucleic acids |
JP6604942B2 (ja) * | 2013-06-13 | 2019-11-13 | バイオマトリカ,インク. | 細胞安定化 |
AU2014340089B2 (en) | 2013-10-22 | 2019-09-26 | Berkeley Lights, Inc. | Microfluidic devices having isolation pens and methods of testing biological micro-objects with same |
US9889445B2 (en) | 2013-10-22 | 2018-02-13 | Berkeley Lights, Inc. | Micro-fluidic devices for assaying biological activity |
US20150166326A1 (en) * | 2013-12-18 | 2015-06-18 | Berkeley Lights, Inc. | Capturing Specific Nucleic Acid Materials From Individual Biological Cells In A Micro-Fluidic Device |
US20170105960A1 (en) | 2014-04-08 | 2017-04-20 | Neurovive Pharmaceutical Ab | Prodrugs of Succinic Acid for Increasing ATP Production |
US20150306599A1 (en) | 2014-04-25 | 2015-10-29 | Berkeley Lights, Inc. | Providing DEP Manipulation Devices And Controllable Electrowetting Devices In The Same Microfluidic Apparatus |
US20150306598A1 (en) | 2014-04-25 | 2015-10-29 | Berkeley Lights, Inc. | DEP Force Control And Electrowetting Control In Different Sections Of The Same Microfluidic Apparatus |
SG11201608499XA (en) | 2014-04-25 | 2016-11-29 | Berkeley Lights Inc | Providing dep manipulation devices and controllable electrowetting devices in the same microfluidic apparatus |
WO2015188171A1 (en) * | 2014-06-06 | 2015-12-10 | Berkeley Lights, Inc. | Isolating microfluidic structures and trapping bubbles |
EP3155395B1 (en) * | 2014-06-10 | 2021-06-02 | Biomatrica, INC. | Methods and compositions for stabilization of nucleic acids in a blood sample at ambient temperatures |
EP3252040B1 (en) * | 2015-01-27 | 2023-04-19 | BGI Shenzhen | Stabilizer for preserving biological samples |
CN105158455B (zh) * | 2015-09-17 | 2018-10-16 | 深圳市钠科生物有限公司 | 一种提高样品检测精度和准确性的生物样品采集方法、装置、系统、生物样品稳定试剂及应用 |
-
2017
- 2017-03-30 AU AU2017239666A patent/AU2017239666B2/en active Active
- 2017-03-30 WO PCT/US2017/025065 patent/WO2017173105A1/en active Application Filing
- 2017-03-30 EP EP21217724.0A patent/EP4043475B1/en active Active
- 2017-03-30 JP JP2018550743A patent/JP7019590B2/ja active Active
- 2017-03-30 KR KR1020187031380A patent/KR102451535B1/ko active IP Right Grant
- 2017-03-30 CA CA3020728A patent/CA3020728A1/en active Pending
- 2017-03-30 CN CN201780033808.1A patent/CN109311930B/zh active Active
- 2017-03-30 KR KR1020227034059A patent/KR20220139426A/ko not_active Application Discontinuation
- 2017-03-30 DK DK17776666.4T patent/DK3436469T3/da active
- 2017-03-30 EP EP17776666.4A patent/EP3436469B1/en active Active
- 2017-03-30 SG SG11201808573YA patent/SG11201808573YA/en unknown
- 2017-03-30 CN CN202310097875.7A patent/CN115896099A/zh active Pending
-
2018
- 2018-09-13 US US16/130,634 patent/US20190085375A1/en active Pending
- 2018-09-27 IL IL262019A patent/IL262019A/en unknown
-
2022
- 2022-02-02 JP JP2022014717A patent/JP2022064981A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
KR20220139426A (ko) | 2022-10-14 |
CN115896099A (zh) | 2023-04-04 |
WO2017173105A1 (en) | 2017-10-05 |
EP4043475B1 (en) | 2023-09-20 |
AU2017239666B2 (en) | 2021-07-29 |
CN109311930B (zh) | 2023-02-24 |
KR102451535B1 (ko) | 2022-10-05 |
EP4043475A1 (en) | 2022-08-17 |
CA3020728A1 (en) | 2017-10-05 |
IL262019A (en) | 2018-10-31 |
EP3436469A4 (en) | 2019-12-11 |
KR20180131583A (ko) | 2018-12-10 |
SG11201808573YA (en) | 2018-10-30 |
JP2019513363A (ja) | 2019-05-30 |
EP3436469B1 (en) | 2022-01-05 |
CN109311930A (zh) | 2019-02-05 |
AU2017239666A1 (en) | 2018-11-08 |
US20190085375A1 (en) | 2019-03-21 |
JP2022064981A (ja) | 2022-04-26 |
EP3436469A1 (en) | 2019-02-06 |
JP7019590B2 (ja) | 2022-02-15 |
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