DK3400072T3 - Formuleringer til behandling af blærecancer - Google Patents

Formuleringer til behandling af blærecancer Download PDF

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Publication number
DK3400072T3
DK3400072T3 DK17736515.2T DK17736515T DK3400072T3 DK 3400072 T3 DK3400072 T3 DK 3400072T3 DK 17736515 T DK17736515 T DK 17736515T DK 3400072 T3 DK3400072 T3 DK 3400072T3
Authority
DK
Denmark
Prior art keywords
formulations
treatment
bladder cancer
bladder
cancer
Prior art date
Application number
DK17736515.2T
Other languages
English (en)
Inventor
Guru V Betageri
Natarajan Venkatesan
Michael G Oefelein
Ramachandran Thirucote
Nitin Kumar Swarnakar
Teresa Hong
Original Assignee
Tesorx Pharma Llc
Univ Western Health Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tesorx Pharma Llc, Univ Western Health Sciences filed Critical Tesorx Pharma Llc
Application granted granted Critical
Publication of DK3400072T3 publication Critical patent/DK3400072T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK17736515.2T 2016-01-07 2017-01-09 Formuleringer til behandling af blærecancer DK3400072T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662275941P 2016-01-07 2016-01-07
US201662275936P 2016-01-07 2016-01-07
US201662421137P 2016-11-11 2016-11-11
PCT/US2017/012720 WO2017120586A1 (en) 2016-01-07 2017-01-09 Formulations for treating bladder cancer

Publications (1)

Publication Number Publication Date
DK3400072T3 true DK3400072T3 (da) 2021-03-22

Family

ID=59274569

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17736515.2T DK3400072T3 (da) 2016-01-07 2017-01-09 Formuleringer til behandling af blærecancer

Country Status (23)

Country Link
US (2) US11229602B2 (da)
EP (1) EP3400072B1 (da)
JP (3) JP6697541B2 (da)
KR (1) KR20180103039A (da)
CN (2) CN113181118A (da)
AU (1) AU2017205337B2 (da)
BR (1) BR112018013896A2 (da)
CA (1) CA3009809A1 (da)
CL (1) CL2018001838A1 (da)
CO (1) CO2018007674A2 (da)
CR (1) CR20180388A (da)
DK (1) DK3400072T3 (da)
EA (1) EA038653B1 (da)
ES (1) ES2863659T3 (da)
HK (1) HK1255212A1 (da)
IL (1) IL260346B2 (da)
MX (2) MX2018008267A (da)
MY (1) MY198105A (da)
PE (1) PE20181445A1 (da)
PH (1) PH12018501451A1 (da)
SG (1) SG11201805594PA (da)
WO (1) WO2017120586A1 (da)
ZA (1) ZA201804968B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018047074A1 (en) * 2016-09-07 2018-03-15 Cadila Healthcare Limited Sterile injectable compositions comprising drug micelles
JP7096553B2 (ja) 2016-11-11 2022-07-06 ウエスタン ユニバーシティ オブ ヘルス サイエンシーズ 上部尿路上皮癌の治療方法
WO2018169960A1 (en) * 2017-03-17 2018-09-20 The Johns Hopkins University Nanoparticle formulations for enhanced drug delivery to the bladder
WO2019018619A1 (en) * 2017-07-19 2019-01-24 Tesorx Pharma, Llc LIPOSOMAL FORMULATION OF PACLITAXEL FOR THE TREATMENT OF BLADDER CANCER
JP2021523808A (ja) * 2018-05-04 2021-09-09 ライパック オンコロジー エルエルシー バルーンカテーテル
JP2022506612A (ja) * 2018-11-02 2022-01-17 テソリックス ファーマ, エルエルシー リポソーム強化された腹腔内化学療法
GB201900389D0 (en) 2019-01-11 2019-02-27 Queens Univ Of Belfast Solvent and water-free lipid-based nanoparticles and their methods of manufacture
CN113189315B (zh) * 2021-04-13 2024-01-23 山东省医疗器械产品质量检验中心 评价抗菌导尿管抗菌活性的体外动态模型及其使用方法

Family Cites Families (22)

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CA1330938C (en) 1985-10-18 1994-07-26 Abdul R. Khokhar Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5415869A (en) * 1993-11-12 1995-05-16 The Research Foundation Of State University Of New York Taxol formulation
US5902604A (en) 1995-06-06 1999-05-11 Board Of Regents, The University Of Texas System Submicron liposome suspensions obtained from preliposome lyophilizates
AU2869901A (en) * 2000-02-04 2001-08-14 Lipoxen Technologies Limited Liposomes
US8658202B2 (en) * 2001-04-25 2014-02-25 Western University Of Health Sciences Coated drug delivery formulations
EP1432403B1 (en) * 2001-10-03 2010-07-28 Celator Pharmaceuticals, Inc. Liposome loading with metal ions
KR20050105451A (ko) 2003-02-03 2005-11-04 네오팜 인코포레이티드 안정한 멸균 여과가능한 리포좀 캡슐화 탁산 및 다른항종양제
CA2541117A1 (en) * 2003-10-01 2005-05-06 Children's Hospital & Research Center At Oakland Lipophilic drug delivery vehicle and methods of use thereof
WO2005072776A2 (en) * 2004-01-30 2005-08-11 Instytut Farmaceutyczny Liposomal formulations of the antineoplastic agents
WO2006015120A2 (en) * 2004-07-28 2006-02-09 Sd Pharmaceuticals, Inc. Stable injectable composition of alpha tocopheryl succinate, analogues and salts thereof
EP2013016B8 (en) * 2006-03-29 2014-10-08 Wayne State University Liposomal nanoparticles and other formulations of fenretinide for use in therapy and drug delivery
PL2076244T3 (pl) * 2006-10-10 2017-05-31 Jina Pharmaceuticals Inc. Układy wodne do wytwarzania związków farmaceutycznych na bazie lipidów; kompozycje, sposoby, oraz ich zastosowanie
CN101322689B (zh) 2007-06-11 2012-10-24 江苏先声药物研究有限公司 一种多西他赛长循环脂质体及其冻干粉针的制备方法
WO2010009186A1 (en) 2008-07-15 2010-01-21 The Board Of Trustees Of The University Of Illinois Liposome formulation having hydrophilic and hydrophobic pharmaceutical compounds co-encapsulated therein
US8956600B2 (en) * 2009-08-10 2015-02-17 Taiwan Liposome Co. Ltd. Ophthalmic drug delivery system containing phospholipid and cholesterol
US20110166214A1 (en) 2010-01-07 2011-07-07 Innopharma, Llc Methods and compositions for delivery of taxanes in stable oil-in-water emulsions
KR20150032939A (ko) * 2012-05-09 2015-03-31 웨스턴 유니버시티 오브 헬스 사이언시스 프로리포좀 테스토스테론 제제
CN103570766B (zh) * 2012-08-09 2016-04-13 浙江海昶生物医药技术有限公司 一种新型铂类脂质体制剂及其制备方法
CN103768018A (zh) * 2012-10-17 2014-05-07 南京绿叶思科药业有限公司 一种卡巴他赛脂质体注射剂及其制备方法
EP2968142A1 (en) 2013-03-13 2016-01-20 Mallinckrodt LLC Liposomal cisplatin compositions for cancer therapy
BR112015022819A8 (pt) * 2013-03-13 2019-11-26 Mallinckrodt Llc método para a preparação de um taxano lipossomal, composição compreendendo um lipossoma e taxano lipossomal
JP7096553B2 (ja) * 2016-11-11 2022-07-06 ウエスタン ユニバーシティ オブ ヘルス サイエンシーズ 上部尿路上皮癌の治療方法

Also Published As

Publication number Publication date
IL260346A (en) 2018-08-30
EA201891575A1 (ru) 2019-01-31
AU2017205337B2 (en) 2022-09-08
HK1255212A1 (zh) 2019-08-09
US20210267896A1 (en) 2021-09-02
EP3400072B1 (en) 2020-12-30
MY198105A (en) 2023-08-02
CA3009809A1 (en) 2017-07-13
EP3400072A1 (en) 2018-11-14
CN108136217B (zh) 2021-04-30
JP2020002181A (ja) 2020-01-09
MX2020013858A (es) 2021-03-25
ES2863659T3 (es) 2021-10-11
WO2017120586A1 (en) 2017-07-13
IL260346B1 (en) 2023-04-01
CN113181118A (zh) 2021-07-30
ZA201804968B (en) 2022-10-26
IL260346B2 (en) 2023-08-01
JP6697541B2 (ja) 2020-05-20
JP2018528933A (ja) 2018-10-04
CL2018001838A1 (es) 2018-08-17
CN108136217A (zh) 2018-06-08
US11229602B2 (en) 2022-01-25
CR20180388A (es) 2018-09-11
EP3400072A4 (en) 2020-01-08
AU2017205337A1 (en) 2018-07-19
MX2018008267A (es) 2018-09-28
US20190015334A1 (en) 2019-01-17
JP2022168210A (ja) 2022-11-04
KR20180103039A (ko) 2018-09-18
PE20181445A1 (es) 2018-09-12
PH12018501451A1 (en) 2019-03-11
SG11201805594PA (en) 2018-07-30
CO2018007674A2 (es) 2018-08-10
EA038653B1 (ru) 2021-09-29
BR112018013896A2 (pt) 2018-12-18

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