DK3385294T3 - Isocyanat-funktionel præpolymer til et biologisk nedbrydeligt vævsklæbemiddel - Google Patents

Isocyanat-funktionel præpolymer til et biologisk nedbrydeligt vævsklæbemiddel Download PDF

Info

Publication number
DK3385294T3
DK3385294T3 DK18154905.6T DK18154905T DK3385294T3 DK 3385294 T3 DK3385294 T3 DK 3385294T3 DK 18154905 T DK18154905 T DK 18154905T DK 3385294 T3 DK3385294 T3 DK 3385294T3
Authority
DK
Denmark
Prior art keywords
isocyanate functional
tissue adhesive
functional prepolymer
biodegradable tissue
biodegradable
Prior art date
Application number
DK18154905.6T
Other languages
English (en)
Inventor
Heike Heckroth
Christoph Eggert
Jörg Hofmann
Klaus Lorenz
Original Assignee
Adhesys Medical Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adhesys Medical Gmbh filed Critical Adhesys Medical Gmbh
Application granted granted Critical
Publication of DK3385294T3 publication Critical patent/DK3385294T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4833—Polyethers containing oxyethylene units
    • C08G18/4837—Polyethers containing oxyethylene units and other oxyalkylene units
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4866—Polyethers having a low unsaturation value
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4887—Polyethers containing carboxylic ester groups derived from carboxylic acids other than acids of higher fatty oils or other than resin acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/73—Polyisocyanates or polyisothiocyanates acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
    • C08G65/2642—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds characterised by the catalyst used
    • C08G65/2645—Metals or compounds thereof, e.g. salts
    • C08G65/2663—Metal cyanide catalysts, i.e. DMC's
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
    • C08G65/33348—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing isocyanate group
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2230/00—Compositions for preparing biodegradable polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/05—Polymer mixtures characterised by other features containing polymer components which can react with one another
DK18154905.6T 2011-12-20 2012-12-17 Isocyanat-funktionel præpolymer til et biologisk nedbrydeligt vævsklæbemiddel DK3385294T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11194416 2011-12-20
EP12801750.6A EP2794710B1 (de) 2011-12-20 2012-12-17 Isocyanatfunktionelles präpolymer für einen biologisch abbaubaren gewebeklebstoff

Publications (1)

Publication Number Publication Date
DK3385294T3 true DK3385294T3 (da) 2021-02-08

Family

ID=47358480

Family Applications (2)

Application Number Title Priority Date Filing Date
DK12801750.6T DK2794710T3 (da) 2011-12-20 2012-12-17 Isocyanat-funktionel præpolymer til et biologisk nedbrydeligt vævsklæbestof
DK18154905.6T DK3385294T3 (da) 2011-12-20 2012-12-17 Isocyanat-funktionel præpolymer til et biologisk nedbrydeligt vævsklæbemiddel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK12801750.6T DK2794710T3 (da) 2011-12-20 2012-12-17 Isocyanat-funktionel præpolymer til et biologisk nedbrydeligt vævsklæbestof

Country Status (16)

Country Link
US (2) US9375509B2 (da)
EP (3) EP3786207A1 (da)
JP (1) JP6097764B2 (da)
CN (2) CN108570140A (da)
CY (1) CY1121022T1 (da)
DK (2) DK2794710T3 (da)
ES (2) ES2846300T3 (da)
HK (1) HK1201547A1 (da)
HR (1) HRP20181653T1 (da)
HU (1) HUE040031T2 (da)
LT (1) LT2794710T (da)
PL (1) PL2794710T3 (da)
PT (1) PT2794710T (da)
RS (1) RS57933B1 (da)
SI (1) SI2794710T1 (da)
WO (1) WO2013092504A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105237757B (zh) * 2014-07-11 2017-10-27 中国石油化工股份有限公司 用于氧化烯烃与丙交酯开环共聚的催化剂
CN106512077B (zh) * 2016-09-20 2019-02-26 安徽思维特生物科技有限公司 一种利用明胶制备的温敏型止血凝胶用促凝助剂
CN107583100B (zh) * 2017-09-26 2019-08-20 华南理工大学 一种Si基聚氨酯医用胶黏剂的制备方法与应用
WO2019241484A1 (en) 2018-06-14 2019-12-19 Ecolab Usa Inc. Carboxy alkyl-ester anti-agglomerants for the control of natural gas hydrates
EP3914664A4 (en) 2019-01-22 2022-09-21 Zymergen Inc. ELASTOMERIC ADHESIVES COMPRISING BIODERIVATIVE COMPOUNDS
EP3698723A1 (de) 2019-02-20 2020-08-26 Adhesys Medical GmbH Applikator für einen zwei-komponenten gewebekleber
EP3808385A1 (de) * 2019-10-15 2021-04-21 Adhesys Medical GmbH Kit aus einem zwei-komponenten gewebekleber und einer temporären schutzabdeckung hierfür sowie dessen verwendung
WO2021259847A1 (en) 2020-06-26 2021-12-30 Covestro Deutschland Ag Polyurethanes based on terminal diol- and diaminopolyphosphazenes and their hydrogels
WO2021259848A1 (en) 2020-06-26 2021-12-30 Covestro Deutschland Ag Polyurethanes based on side chain diol- and diaminopolyphosphazenes and their hydrogels
WO2022013345A1 (de) 2020-07-17 2022-01-20 Adhesys Medical Gmbh Kit aus einem zwei-komponenten gewebekleber und einer textilen struktur zur stärkung des bindegewebes nach einer operation sowie dessen verwendung
CN112263706B (zh) * 2020-10-12 2022-05-13 苏州度博迈医疗科技有限公司 一种可生物降解的生物粘合剂及其制备方法
CN112521294B (zh) * 2020-12-15 2022-11-08 万华化学集团股份有限公司 一种季铵盐型阳离子聚天门冬氨酸酯及其制备方法和用途
DE102021102484A1 (de) 2021-02-03 2022-08-04 Adhesys Medical Gmbh Kit für die Gefäßanastomose aus einem zwei-Komponenten Gewebekleber und einer Gefäßprothese sowie dessen Verwendung
DE102021106358A1 (de) 2021-03-16 2022-09-22 Adhesys Medical Gmbh Gewebekleber in Form eines Zweikomponenten-Klebstoffs zur Verwendung bei der Pankreasanastomose im Rahmen der Pankreasresektion
EP4104870A1 (de) 2021-06-15 2022-12-21 Adhesys Medical GmbH Gewebekleber in form eines zweikomponenten-klebstoffs zur verwendung als bakterielle barriere bei der wundbehandlung, insbesondere nach chirurgischen eingriffen
CN114053474A (zh) * 2021-11-24 2022-02-18 华南理工大学 一种具备止血功能的医用胶粘剂及其使用方法
CN114380973B (zh) * 2021-12-10 2023-03-21 华南理工大学 一种基于胆汁酸分子的自修复聚氨酯弹性体及其制备方法
CN114773562B (zh) * 2022-04-27 2023-07-25 广东粤港澳大湾区黄埔材料研究院 生物功能型单组分医用胶粘剂及其制备方法、应用
WO2023249854A1 (en) * 2022-06-23 2023-12-28 Covestro Llc Low viscosity aspartate terminated prepolymers for adhesive applications
EP4321549A1 (en) * 2022-08-09 2024-02-14 Covestro LLC Low viscosity aspartate terminated prepolymers for adhesive applications

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1063525A (en) 1963-02-14 1967-03-30 Gen Tire & Rubber Co Organic cyclic oxide polymers, their preparation and tires prepared therefrom
US3829505A (en) 1970-02-24 1974-08-13 Gen Tire & Rubber Co Polyethers and method for making the same
US3941849A (en) 1972-07-07 1976-03-02 The General Tire & Rubber Company Polyethers and method for making the same
CA1155871A (en) 1980-10-16 1983-10-25 Gencorp Inc. Method for treating polypropylene ether and poly-1,2- butylene ether polyols
US4721818A (en) 1987-03-20 1988-01-26 Atlantic Richfield Company Purification of polyols prepared using double metal cyanide complex catalysts
JPS63278924A (ja) * 1987-05-09 1988-11-16 Bio Material Yunibaasu:Kk 生体内分解吸収性ウレタンプレポリマ−
US4877906A (en) 1988-11-25 1989-10-31 Arco Chemical Technology, Inc. Purification of polyols prepared using double metal cyanide complex catalysts
EP0406440A4 (en) 1989-01-06 1991-05-08 Asahi Glass Company Ltd. Production of polyether
US4987271A (en) 1989-02-17 1991-01-22 Asahi Glass Company, Ltd. Method for purifying a polyoxyalkylene alcohol
US5010047A (en) 1989-02-27 1991-04-23 Arco Chemical Technology, Inc. Recovery of double metal cyanide complex catalyst from a polymer
US5391722A (en) 1990-03-30 1995-02-21 Olin Corporation Acid-catalyzed fabrication of precursors for use in making polyols using double metal cyanide catalysts
US5032671A (en) * 1990-09-04 1991-07-16 Arco Chemical Technology, Inc. Preparation of lactone polymers using double metal cyanide catalysts
JP2653236B2 (ja) 1990-10-05 1997-09-17 旭硝子株式会社 ポリエーテル化合物の製造方法
US5099075A (en) 1990-11-02 1992-03-24 Olin Corporation Process for removing double metal cyanide catalyst residues from a polyol
US5158922A (en) 1992-02-04 1992-10-27 Arco Chemical Technology, L.P. Process for preparing metal cyanide complex catalyst
JPH05295075A (ja) * 1992-04-22 1993-11-09 Asahi Glass Co Ltd ポリウレタンの製造方法
US5470813A (en) 1993-11-23 1995-11-28 Arco Chemical Technology, L.P. Double metal cyanide complex catalysts
US5712216A (en) 1995-05-15 1998-01-27 Arco Chemical Technology, L.P. Highly active double metal cyanide complex catalysts
US5482908A (en) 1994-09-08 1996-01-09 Arco Chemical Technology, L.P. Highly active double metal cyanide catalysts
US5545601A (en) 1995-08-22 1996-08-13 Arco Chemical Technology, L.P. Polyether-containing double metal cyanide catalysts
US5627120A (en) 1996-04-19 1997-05-06 Arco Chemical Technology, L.P. Highly active double metal cyanide catalysts
US5714428A (en) 1996-10-16 1998-02-03 Arco Chemical Technology, L.P. Double metal cyanide catalysts containing functionalized polymers
DE19710967C1 (de) 1997-03-17 1998-10-22 Karl Heinz Koeppen Breitbandlautsprecher
US6193997B1 (en) 1998-09-27 2001-02-27 Generex Pharmaceuticals Inc. Proteinic drug delivery system using membrane mimetics
DE19905611A1 (de) 1999-02-11 2000-08-17 Bayer Ag Doppelmetallcyanid-Katalysatoren für die Herstellung von Polyetherpolyolen
DE19958355A1 (de) 1999-12-03 2001-06-07 Bayer Ag Verfahren zur Herstellung von DMC-Katalysatoren
ATE270148T1 (de) 2000-04-20 2004-07-15 Bayer Materialscience Ag Verfahren zur herstellung von dmc-katalysatoren
AU2002316314B8 (en) * 2001-07-31 2008-04-03 Covidien Lp Bioabsorbable adhesive compounds and compositions
US20040068078A1 (en) * 2001-12-12 2004-04-08 Milbocker Michael T. In situ polymerizing medical compositions
US6710096B2 (en) 2002-07-22 2004-03-23 Basf Corporation Polyether polyol for foam applications
JP4145123B2 (ja) 2002-11-18 2008-09-03 株式会社オンダ製作所 継手
JP5528656B2 (ja) * 2003-01-09 2014-06-25 ポリガニックス ビー． ブイ． 生体医用フォーム
US20050129733A1 (en) * 2003-12-09 2005-06-16 Milbocker Michael T. Surgical adhesive and uses therefore
EP1737898A1 (en) * 2004-04-15 2007-01-03 The University of Utah Research Foundation Bioresponsive polymer system for delivery of microbicides
CN1961017B (zh) 2004-05-31 2010-08-25 旭硝子株式会社 聚氨酯弹性体及其制造方法
EP1771490B1 (en) * 2004-07-26 2019-01-02 Synthes GmbH Biocompatible, biodegradable polyurethane materials with controlled hydrophobic to hydrophilic ratio
US7977501B2 (en) 2006-07-24 2011-07-12 Bayer Materialscience Llc Polyether carbonate polyols made via double metal cyanide (DMC) catalysis
US7968212B2 (en) * 2006-12-18 2011-06-28 Ppg Industries Ohio, Inc. Triamine/aspartate curative and coatings comprising the same
US20100316691A2 (en) * 2007-01-19 2010-12-16 University Of Utah Research Foundation Biodegradable intravaginal medical device for delivery of therapeutics
EP2011808A1 (de) 2007-07-03 2009-01-07 Bayer MaterialScience AG Medizinische Klebstoffe für die Chirurgie
JP2009033369A (ja) 2007-07-26 2009-02-12 Sony Corp 記録装置、再生装置、記録再生装置、撮像装置、記録方法およびプログラム
EP2083025A1 (de) * 2008-01-24 2009-07-29 Bayer MaterialScience AG Medizinische Klebstoffe für die Chirurgie
EP2095832A1 (de) 2008-02-28 2009-09-02 Bayer MaterialScience AG Polyharnstoff-Systeme und deren Anwendung als postoperative Adhäsionsbarrieren, Filme und Verbundteile.
EP2145634A1 (de) 2008-07-17 2010-01-20 Bayer MaterialScience AG Medizinische Klebstoffe zur Stillung schwerwiegender Blutungen und Abdichtung von Leckagen
CA2780919A1 (en) * 2009-10-21 2011-04-28 Bayer Materialscience Ag Biodegradable hydrogel
EP2336212B1 (de) * 2009-12-12 2012-03-07 Bayer MaterialScience AG Klebstoffverbundsystem zum Abdecken, Verschliessen oder Verkleben von Zellgewebe
JP5829267B2 (ja) 2010-05-18 2015-12-09 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ ポリエーテルカーボネートポリオールの製造方法
EP2673310B1 (de) 2011-02-09 2014-11-19 Medical Adhesive Revolution GmbH Gewebekleber auf basis stickstoffmodifizierter aspartate

Also Published As

Publication number Publication date
HK1201547A1 (en) 2015-09-04
DK2794710T3 (da) 2018-12-10
US9468701B2 (en) 2016-10-18
CN104105731A (zh) 2014-10-15
CY1121022T1 (el) 2019-12-11
US9375509B2 (en) 2016-06-28
JP6097764B2 (ja) 2017-03-15
EP2794710A1 (de) 2014-10-29
EP3385294A1 (de) 2018-10-10
HRP20181653T1 (hr) 2018-12-14
JP2015508426A (ja) 2015-03-19
LT2794710T (lt) 2018-11-26
EP3385294B1 (de) 2020-11-11
EP3786207A1 (de) 2021-03-03
PL2794710T3 (pl) 2019-02-28
WO2013092504A1 (de) 2013-06-27
US20160256595A1 (en) 2016-09-08
EP2794710B1 (de) 2018-08-15
SI2794710T1 (sl) 2018-12-31
ES2846300T3 (es) 2021-07-28
US20140316076A1 (en) 2014-10-23
CN108570140A (zh) 2018-09-25
RS57933B1 (sr) 2019-01-31
HUE040031T2 (hu) 2019-02-28
ES2694826T3 (es) 2018-12-27
PT2794710T (pt) 2018-11-22

Similar Documents

Publication Publication Date Title
DK3385294T3 (da) Isocyanat-funktionel præpolymer til et biologisk nedbrydeligt vævsklæbemiddel
BRDI7003230S (pt) Configuração aplicada a calçado
CO6801703A2 (es) Adhesivos mofificados con base en diisocianato de difenilmetano
DK2529054T3 (da) Udlægningsmaskine til et fleksibelt aflangt element
ZA201201445B (en) Adhesive bandage
BR112013020709A2 (pt) espuma de poliuretano
ZA201201444B (en) Adhesive bandage
BR112015003569A2 (pt) adesivo de poliuretano estrutural.
BR112013015393A2 (pt) método para a preparação de poliéter polióis
BR112015000514A2 (pt) adesivo de poliuretano estrutural.
IT1393465B1 (it) Poliuretano idrofilico a pettine
DK2665363T3 (da) Chlorhexidingluconat-indeholdende klæbemiddel
EP2786752A4 (en) ROPINIUM-CONTAINING HEFTPFLASTER
DK2510030T3 (da) Polyurethan-præpolymerer
DK2764031T3 (da) 2-komponent polyurethan-coating på fibercement
SMT201600137B (it) Procedimento di fabbricazione di etichette-valvola adesive flessibili
BR112012018944A2 (pt) capacho colado e método para a fabricação de um capacho colado
DK2751239T3 (da) Flerdelskitsystem til fremstilling af et desinficeringsmiddel
EP2799066A4 (en) ADHESIVE STAMP CONTAINING TOLTERODINE
EP2789335A4 (en) ADHESIVE STAMP
BR112013012321A2 (pt) método para a produção de espumas de poliuretano flexíveis
DK2408564T3 (da) Antispinsystem til et kegleknuserhoved
EP2752188A4 (en) ADHESIVE PLASTER
DE202011103901U8 (de) Fahrzeuganhängerstütze
ES1072011Y (es) Calzado autoventilado