DK337485A - Phosphatidylforbindelser samt deres fremstilling og anvendelse - Google Patents

Phosphatidylforbindelser samt deres fremstilling og anvendelse Download PDF

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Publication number
DK337485A
DK337485A DK337485A DK337485A DK337485A DK 337485 A DK337485 A DK 337485A DK 337485 A DK337485 A DK 337485A DK 337485 A DK337485 A DK 337485A DK 337485 A DK337485 A DK 337485A
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Prior art keywords
aliphatic
substituted
etherified
alpha
compounds
Prior art date
Application number
DK337485A
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English (en)
Other versions
DK337485D0 (da
Inventor
Gerhard Baschang
Bruno Fechtig
Albert Hartmann
Bohumir Lukas
Oskar Wacker
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK337485D0 publication Critical patent/DK337485D0/da
Publication of DK337485A publication Critical patent/DK337485A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/091Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Tires In General (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK337485A 1984-07-25 1985-07-24 Phosphatidylforbindelser samt deres fremstilling og anvendelse DK337485A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH359884 1984-07-25

Publications (2)

Publication Number Publication Date
DK337485D0 DK337485D0 (da) 1985-07-24
DK337485A true DK337485A (da) 1986-01-26

Family

ID=4259440

Family Applications (1)

Application Number Title Priority Date Filing Date
DK337485A DK337485A (da) 1984-07-25 1985-07-24 Phosphatidylforbindelser samt deres fremstilling og anvendelse

Country Status (17)

Country Link
US (1) US4788182A (da)
EP (1) EP0169812B1 (da)
JP (1) JPS6143193A (da)
AT (1) ATE45744T1 (da)
AU (1) AU582772B2 (da)
DD (1) DD247680A5 (da)
DE (1) DE3572491D1 (da)
DK (1) DK337485A (da)
ES (1) ES8701186A1 (da)
FI (1) FI78300C (da)
GR (1) GR851825B (da)
HU (1) HU194896B (da)
IL (1) IL75886A (da)
NO (1) NO852953L (da)
NZ (1) NZ212860A (da)
PT (1) PT80851B (da)
ZA (1) ZA855580B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL84387A0 (en) * 1987-11-06 1990-02-09 Rapaport Erich Pharmaceutical compositions containing a substituted phosphatide
IT1230140B (it) * 1989-05-03 1991-10-14 Fidia Spa Derivati della serina, loro processo di preparazione e impiego in terapia umana
DE3929217A1 (de) * 1989-09-02 1991-03-07 Boehringer Mannheim Gmbh Verwendung von phospholipid-derivaten als antivirale arzneimittel und neue phospholipide
US5136032A (en) * 1989-12-07 1992-08-04 Daicel Chemical Industries, Ltd. Method for separating phosphopolyol compounds using a separating agent
US5144045A (en) * 1990-11-13 1992-09-01 American Cyanamid Company Phosphocholine derivative inhibitors of phospholipase A2
DE4229877C2 (de) * 1992-09-04 1994-09-15 Max Delbrueck Centrum Phospho- bzw. Phosphono-(N-acyl)-serine und ihre Herstellung
MXPA03007455A (es) * 2001-02-21 2004-07-30 Basf Ag Metodo y produccion de acido d-pantotenico y las sales de este como adyuvante en productos alimenticios para animales.
DE10109898A1 (de) 2001-02-21 2002-09-05 Novosom Gmbh Lipide mit veränderlicher Ladung
DE10109897A1 (de) 2001-02-21 2002-11-07 Novosom Ag Fakultativ kationische Liposomen und Verwendung dieser
DE10207178A1 (de) * 2002-02-19 2003-09-04 Novosom Ag Komponenten für die Herstellung amphoterer Liposomen
DE10207177A1 (de) * 2002-02-19 2003-09-04 Novosom Ag Fakultativ kationische Lipide
US7858117B2 (en) 2002-02-21 2010-12-28 Novosom Ag Amphoteric liposomes and their use
WO2005039504A2 (en) * 2003-10-24 2005-05-06 Eisai Co., Ltd. Compounds and methods for treating toll-like receptor 2-related diseases and conditions
CA2889116C (en) 2012-10-31 2020-09-01 Akzo Nobel Chemicals International B.V. Phosphated compositions as adhesion promoters
JP5914418B2 (ja) * 2013-06-26 2016-05-11 富士フイルム株式会社 脂質粒子、核酸送達キャリア、核酸送達キャリア製造用組成物、脂質粒子の製造方法及び遺伝子導入方法
CN111808131B (zh) * 2019-04-11 2021-09-17 中国科学院大连化学物理研究所 一对有效抑制Aβ(1-40)聚集和纤维化的手性磷脂分子及其制备方法和应用
CN114369115A (zh) * 2021-12-07 2022-04-19 中国科学院大连化学物理研究所 一对对PrP106-126聚集有抑制作用的手性磷脂

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2436699A (en) * 1947-06-12 1948-02-24 Nasa Nitrogenous diacyl-glycerophosphates
US2447715A (en) * 1947-06-12 1948-08-24 Us Agriculture Esters of diacyl-glycerophosphoric acids
DE1543937C3 (de) * 1966-01-14 1982-12-09 Unilever N.V., 3000 Rotterdam Verwendung modifizierter kephalinhaltiger Phosphatidgemische als Emulgatoren für O/W-Emulsionen und Verfahren zur Herstellung solcher Emulgatoren
US4119714A (en) * 1970-02-27 1978-10-10 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E. V. Glycerin-alkylether-(1)-phosphoric acid-(3)-monocholine esters as enhancers of the natural resistance of the mammalian organism against non-carcinogenic pathogens
US3663235A (en) * 1970-04-13 1972-05-16 Lever Brothers Ltd Process of preparing margarine containing diacyglycerophatide
US4235792A (en) * 1977-04-14 1980-11-25 The Governing Council Of The University Of Toronto Immunological materials
GB2046092B (en) * 1979-03-05 1983-11-02 Toyama Chemical Co Ltd Pharmaceutical composition containing a lysophospholid and a phospholipid
US4254115A (en) * 1979-06-18 1981-03-03 A. Nattermann & Cie. Gmbh Phospholipid derivative with an antilipemic and antiarteriosclerotic effect
CH641811A5 (en) * 1979-06-18 1984-03-15 Nattermann A & Cie Antilipaemic and antiarteriosclerotic phospholipid derivative
GB2051069B (en) * 1979-06-18 1983-08-24 Nattermann A & Cie Phospholipid derivatives useful in therapy as antilepaemics and antiarteriosclerotics and compositions containing them
FI75578C (fi) * 1979-07-25 1988-07-11 Ciba Geigy Ag Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider.
FI803077A (fi) * 1979-10-12 1981-04-13 Ciba Geigy Ag Foerfarande foer framstaellning av myramylpeptider
JPS5772914A (en) * 1980-10-22 1982-05-07 Takeda Chem Ind Ltd Antitumor agent
GR78246B (da) * 1981-01-23 1984-09-26 Ciba Geigy Ag
US4426330A (en) * 1981-07-20 1984-01-17 Lipid Specialties, Inc. Synthetic phospholipid compounds
US4534899A (en) * 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
IT1171432B (it) * 1981-08-03 1987-06-10 Fidia Farmaceutici Amidi organiche derivate da lipidi azotati utilizzabili come farmaci
US4607011A (en) * 1982-05-20 1986-08-19 Board Of Trustees, University Of Illinois Accumulation and isolation of N-acylphosphatidylserine
ATE23536T1 (de) * 1982-07-23 1986-11-15 Ciba Geigy Ag Neue muramylpeptide und verfahren zu ihrer herstellung.
US4666893A (en) * 1983-02-15 1987-05-19 St. Thomas Institute Methods of inducing resistance to bacterial and viral infections

Also Published As

Publication number Publication date
ZA855580B (en) 1986-03-26
ES8701186A1 (es) 1986-11-16
US4788182A (en) 1988-11-29
FI852841L (fi) 1986-01-26
GR851825B (da) 1985-11-26
IL75886A0 (en) 1985-12-31
FI78300C (fi) 1989-07-10
FI852841A0 (fi) 1985-07-22
HUT38360A (en) 1986-05-28
DK337485D0 (da) 1985-07-24
IL75886A (en) 1989-10-31
ES545486A0 (es) 1986-11-16
DD247680A5 (de) 1987-07-15
EP0169812A1 (de) 1986-01-29
NZ212860A (en) 1990-03-27
NO852953L (no) 1986-01-27
EP0169812B1 (de) 1989-08-23
PT80851A (de) 1985-08-01
FI78300B (fi) 1989-03-31
JPS6143193A (ja) 1986-03-01
HU194896B (en) 1988-03-28
ATE45744T1 (de) 1989-09-15
PT80851B (pt) 1987-11-30
AU4537885A (en) 1986-01-30
AU582772B2 (en) 1989-04-13
DE3572491D1 (en) 1989-09-28

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Legal Events

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AHB Application shelved due to non-payment