DK3313869T3 - Cyklisk rgd-cellebindende motiv og anvendelser deraf - Google Patents

Cyklisk rgd-cellebindende motiv og anvendelser deraf Download PDF

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Publication number
DK3313869T3
DK3313869T3 DK16731887.2T DK16731887T DK3313869T3 DK 3313869 T3 DK3313869 T3 DK 3313869T3 DK 16731887 T DK16731887 T DK 16731887T DK 3313869 T3 DK3313869 T3 DK 3313869T3
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Denmark
Prior art keywords
cell binding
cyclic rgd
rgd cell
binding design
design
Prior art date
Application number
DK16731887.2T
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Danish (da)
English (en)
Inventor
My Hedhammar
Original Assignee
Spiber Tech Ab
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Publication of DK3313869T3 publication Critical patent/DK3313869T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Insects & Arthropods (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Sustainable Development (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK16731887.2T 2015-06-26 2016-06-23 Cyklisk rgd-cellebindende motiv og anvendelser deraf DK3313869T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15174072 2015-06-26
PCT/EP2016/064543 WO2016207281A1 (en) 2015-06-26 2016-06-23 Cyclic rgd cell-binding motif and uses thereof

Publications (1)

Publication Number Publication Date
DK3313869T3 true DK3313869T3 (da) 2021-05-10

Family

ID=53513980

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16731887.2T DK3313869T3 (da) 2015-06-26 2016-06-23 Cyklisk rgd-cellebindende motiv og anvendelser deraf

Country Status (8)

Country Link
US (2) US10316069B2 (enExample)
EP (1) EP3313869B1 (enExample)
JP (1) JP6863976B2 (enExample)
KR (1) KR20180022873A (enExample)
CN (1) CN108026152B (enExample)
CA (1) CA2990523C (enExample)
DK (1) DK3313869T3 (enExample)
WO (1) WO2016207281A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3263593A1 (en) * 2016-07-01 2018-01-03 Anna Rising Engineered spider silk proteins and uses thereof
JP7029748B2 (ja) * 2018-01-26 2022-03-04 小島プレス工業株式会社 植毛品及びその製造方法
EP3967704A4 (en) * 2019-06-11 2022-08-31 FUJIFILM Corporation CYCLIC PEPTIDE, CELLULAR SCAFFOLDING MATERIAL, CELL SEPARATION MATERIAL AND CULTURE MEDIUM
GB2588421B (en) * 2019-10-23 2021-11-03 Neoss Ltd Surgical membrane
US20240207325A1 (en) 2021-04-12 2024-06-27 Biocrine Ab Pancreatic Islets as Protein Factories
JP2025526686A (ja) 2022-08-08 2025-08-15 スピベル テクノロジーズ アクティエボラーグ ヒト多能性幹細胞からの膵島のインビトロ誘導
CN120344547A (zh) * 2022-12-16 2025-07-18 东亚合成株式会社 合成肽和构建体
CN120157740B (zh) * 2025-05-20 2025-08-01 广州飞来爱生命科技有限公司 一种脐带间充质干细胞制剂及其在治疗卵巢疾病中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1465591A (zh) * 2002-06-24 2004-01-07 三九生物科技股份有限公司 氨基酸序列精氨酸-甘氨酸-天冬氨酸/纤维素亲和力功能区细胞贴附因子及其制造方法
CN100436477C (zh) * 2005-03-25 2008-11-26 复旦大学附属中山医院 含精-甘-天冬氨酸序列环肽及其主动靶向脂质体
JP5192391B2 (ja) * 2005-12-30 2013-05-08 スパイバー・テクノロジーズ・アーベー クモ糸タンパク質およびクモ糸タンパク質の生産方法
CN101817873A (zh) * 2010-03-11 2010-09-01 复旦大学 一种促进细胞黏附的多肽及其制备方法
DK2558137T3 (en) * 2010-04-12 2017-07-03 Spiber Tech Ab Methods and combination
AU2013271445B2 (en) * 2012-06-07 2016-12-15 National Cheng Kung University Modified fibronectin fragments or variants and uses thereof
ES2933048T3 (es) * 2012-08-17 2023-01-31 Amsilk Gmbh Uso de polipéptidos de autoensamblaje como adhesivos tisulares
WO2015036619A1 (en) * 2013-09-16 2015-03-19 Spiber Technologies Ab A method and a cell scaffold material for cell culture

Also Published As

Publication number Publication date
EP3313869A1 (en) 2018-05-02
US10316069B2 (en) 2019-06-11
CN108026152A (zh) 2018-05-11
US20190322710A1 (en) 2019-10-24
KR20180022873A (ko) 2018-03-06
US10662230B2 (en) 2020-05-26
JP6863976B2 (ja) 2021-04-21
EP3313869B1 (en) 2021-02-17
US20180170977A1 (en) 2018-06-21
JP2018527404A (ja) 2018-09-20
CA2990523C (en) 2023-01-24
CA2990523A1 (en) 2016-12-29
WO2016207281A1 (en) 2016-12-29
CN108026152B (zh) 2022-03-01

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