JP6863976B2 - 環状ｒｇｄ細胞結合モチーフ及びその使用 - Google Patents

環状ｒｇｄ細胞結合モチーフ及びその使用 Download PDF

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JP6863976B2
JP6863976B2 JP2018518780A JP2018518780A JP6863976B2 JP 6863976 B2 JP6863976 B2 JP 6863976B2 JP 2018518780 A JP2018518780 A JP 2018518780A JP 2018518780 A JP2018518780 A JP 2018518780A JP 6863976 B2 JP6863976 B2 JP 6863976B2
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cell
amino acid
acid residues
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protein
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JP2018527404A (ja
JP2018527404A5 (enExample
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ヘドハンマル ミュー
ヘドハンマル ミュー
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スピベル テクノロジーズ アクティエボラーグ
スピベル テクノロジーズ アクティエボラーグ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Insects & Arthropods (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Materials Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Sustainable Development (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2018518780A 2015-06-26 2016-06-23 環状ｒｇｄ細胞結合モチーフ及びその使用 Active JP6863976B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15174072 2015-06-26
EP15174072.7 2015-06-26
PCT/EP2016/064543 WO2016207281A1 (en) 2015-06-26 2016-06-23 Cyclic rgd cell-binding motif and uses thereof

Publications (3)

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JP2018527404A JP2018527404A (ja) 2018-09-20
JP2018527404A5 JP2018527404A5 (enExample) 2019-07-25
JP6863976B2 true JP6863976B2 (ja) 2021-04-21

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JP2018518780A Active JP6863976B2 (ja) 2015-06-26 2016-06-23 環状ｒｇｄ細胞結合モチーフ及びその使用

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US (2) US10316069B2 (enExample)
EP (1) EP3313869B1 (enExample)
JP (1) JP6863976B2 (enExample)
KR (1) KR20180022873A (enExample)
CN (1) CN108026152B (enExample)
CA (1) CA2990523C (enExample)
DK (1) DK3313869T3 (enExample)
WO (1) WO2016207281A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3263593A1 (en) 2016-07-01 2018-01-03 Anna Rising Engineered spider silk proteins and uses thereof
JP7029748B2 (ja) * 2018-01-26 2022-03-04 小島プレス工業株式会社 植毛品及びその製造方法
WO2020250854A1 (ja) * 2019-06-11 2020-12-17 富士フイルム株式会社 環状ペプチド、細胞足場材、細胞分離材、及び培地
GB2588421B (en) * 2019-10-23 2021-11-03 Neoss Ltd Surgical membrane
WO2022218876A1 (en) 2021-04-12 2022-10-20 Biocrine Ab Pancreatic islet organoids as protein factories
EP4569086A1 (en) 2022-08-08 2025-06-18 Spiber Technologies AB 3d islet formation from endocrine progenitor cells
JPWO2024128081A1 (enExample) * 2022-12-16 2024-06-20
CN120157740B (zh) * 2025-05-20 2025-08-01 广州飞来爱生命科技有限公司 一种脐带间充质干细胞制剂及其在治疗卵巢疾病中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1465591A (zh) * 2002-06-24 2004-01-07 三九生物科技股份有限公司 氨基酸序列精氨酸-甘氨酸-天冬氨酸/纤维素亲和力功能区细胞贴附因子及其制造方法
CN100436477C (zh) * 2005-03-25 2008-11-26 复旦大学附属中山医院 含精-甘-天冬氨酸序列环肽及其主动靶向脂质体
RU2444527C2 (ru) * 2005-12-30 2012-03-10 Спибер Текнолоджиз Аб Рекомбинантный спидроиновый белок главной ампулярной железы, способный к полимеризации, рекомбинантный слитый белок, способный к управляемой полимеризации, полимер спидроинового белка главной ампулярной железы, композиция для управляемой полимеризации, рекомбинантная молекула нуклеиновой кислоты (варианты), способ получения растворимого слитого белка, способ получения полимера спидроинового белка главной ампулярной железы и способ культивирования эукариотических клеток
CN101817873A (zh) * 2010-03-11 2010-09-01 复旦大学 一种促进细胞黏附的多肽及其制备方法
CN102946914B (zh) * 2010-04-12 2015-06-03 思百博技术股份公司 方法及组合物
CA2876135A1 (en) * 2012-06-07 2013-12-12 National Cheng Kung University Modified fibronectin fragments or variants and uses thereof
EP3682912B1 (en) * 2012-08-17 2025-11-26 AMSilk GmbH Use of self-assembling polypeptides as tissue adhesives
WO2015036619A1 (en) * 2013-09-16 2015-03-19 Spiber Technologies Ab A method and a cell scaffold material for cell culture

Also Published As

Publication number Publication date
JP2018527404A (ja) 2018-09-20
US20190322710A1 (en) 2019-10-24
EP3313869A1 (en) 2018-05-02
DK3313869T3 (da) 2021-05-10
CN108026152A (zh) 2018-05-11
US10316069B2 (en) 2019-06-11
CA2990523A1 (en) 2016-12-29
US10662230B2 (en) 2020-05-26
CA2990523C (en) 2023-01-24
CN108026152B (zh) 2022-03-01
EP3313869B1 (en) 2021-02-17
US20180170977A1 (en) 2018-06-21
KR20180022873A (ko) 2018-03-06
WO2016207281A1 (en) 2016-12-29

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