DK326484A - Imidazoler, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne - Google Patents

Imidazoler, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne Download PDF

Info

Publication number
DK326484A
DK326484A DK326484A DK326484A DK326484A DK 326484 A DK326484 A DK 326484A DK 326484 A DK326484 A DK 326484A DK 326484 A DK326484 A DK 326484A DK 326484 A DK326484 A DK 326484A
Authority
DK
Denmark
Prior art keywords
imidazoles
preparations
procedures
compounds
medicinals containing
Prior art date
Application number
DK326484A
Other languages
Danish (da)
English (en)
Other versions
DK326484D0 (da
Inventor
Volkhard Austel
Joachim Heider
Norbert Hauel
Manfred Reiffen
Jacobus C A Van Meel
Willi Diederen
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK326484D0 publication Critical patent/DK326484D0/da
Publication of DK326484A publication Critical patent/DK326484A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28Oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28Oxygen atom
    • C07D473/30Oxygen atom attached in position 6, e.g. hypoxanthine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/40Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK326484A 1983-07-05 1984-07-03 Imidazoler, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne DK326484A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833324115 DE3324115A1 (de) 1983-07-05 1983-07-05 Neue imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
DK326484D0 DK326484D0 (da) 1984-07-03
DK326484A true DK326484A (da) 1985-01-06

Family

ID=6203136

Family Applications (1)

Application Number Title Priority Date Filing Date
DK326484A DK326484A (da) 1983-07-05 1984-07-03 Imidazoler, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne

Country Status (18)

Country Link
US (2) US4670438A (pt)
EP (1) EP0130461A3 (pt)
JP (1) JPS6036486A (pt)
KR (1) KR850001208A (pt)
AU (1) AU3032384A (pt)
DD (1) DD224851A5 (pt)
DE (1) DE3324115A1 (pt)
DK (1) DK326484A (pt)
ES (4) ES533995A0 (pt)
FI (1) FI842666A (pt)
GR (1) GR82380B (pt)
HU (1) HU194878B (pt)
IL (1) IL72298A0 (pt)
NO (1) NO842684L (pt)
NZ (1) NZ208779A (pt)
PH (1) PH21496A (pt)
PT (1) PT78836B (pt)
ZA (1) ZA845103B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346640A1 (de) * 1983-12-23 1985-07-04 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazolderivate, deren herstellung und diese verbindungen enthaltende arzneimittel
DE3445299A1 (de) * 1984-12-12 1986-06-19 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3522230A1 (de) * 1985-06-21 1987-01-02 Thomae Gmbh Dr K Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
US4783530A (en) * 1986-11-13 1988-11-08 Marion Laboratories, Inc. 8-arylxanthines
GB8804016D0 (en) * 1988-02-22 1988-03-23 Boots Co Plc Therapeutic agents
DE3929864A1 (de) * 1989-09-08 1991-03-14 Nordmark Arzneimittel Gmbh Verfahren zur herstellung von theophyllin-pellets
EP0434038A1 (en) * 1989-12-22 1991-06-26 Takeda Chemical Industries, Ltd. Fused imidazole derivatives, their production and use
US5877176A (en) * 1991-12-26 1999-03-02 Cornell Research Foundation, Inc. Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis
JP2534423B2 (ja) * 1991-12-26 1996-09-18 コーネル・リサーチ・ファンデーション・インコーポレイテッド 酸化窒素の過剰生産から生じる血管失調を阻止する阻害剤
EP0577025A3 (de) * 1992-07-01 1998-02-04 Hoechst Aktiengesellschaft Angiotensin-II-Rezeptorantagonisten zur Behandlung und Prophylaxe von koronaren Herzerkrankungen
AU681875B2 (en) * 1993-02-26 1997-09-11 Schering Corporation 2-benzyl-polycyclic guanine derivatives and process for preparing them
CA2131134A1 (en) * 1993-09-17 1995-03-18 Gerhard Stucky Process for preparing imidazopyridine derivatives
CA2131680C (en) * 1993-09-17 2006-11-07 Gerhard Stucky Process for preparing imidazopyridine derivatives
US5502050A (en) * 1993-11-29 1996-03-26 Cornell Research Foundation, Inc. Blocking utilization of tetrahydrobiopterin to block induction of nitric oxide synthesis
US6887690B2 (en) * 2001-06-22 2005-05-03 Pe Corporation Dye-labeled ribonucleotide triphosphates
JP4127204B2 (ja) * 2003-12-17 2008-07-30 セイコーエプソン株式会社 液晶表示装置の製造方法
US8168658B2 (en) * 2006-02-28 2012-05-01 Merck Sharp & Dohme Corp. Inhibitors of histone deacetylase
JP2010531358A (ja) * 2007-06-27 2010-09-24 メルク・シャープ・エンド・ドーム・コーポレイション ヒストン脱アセチル化酵素阻害剤としてのピリジル及びピリミジニル誘導体
AU2008269154B2 (en) 2007-06-27 2014-06-12 Merck Sharp & Dohme Llc 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
US20090197880A1 (en) * 2007-07-13 2009-08-06 Genelabs Technologies, Inc. Anti-viral compounds, compositions, and methods of use

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660397A (en) * 1970-04-17 1972-05-02 Merck & Co Inc Imidazo(4 5-b)pyrazines
US3922345A (en) * 1971-10-29 1975-11-25 Pfizer Pyrimidinones and hydroxy pyrimidines
US3985891A (en) * 1973-02-03 1976-10-12 Boehringer Ingelheim Gmbh 2-Phenyl-imidazo (4,5-b)pyridines and salts thereof
DE2305339C3 (de) * 1973-02-03 1980-05-08 Dr. Karl Thomae Gmbh, 7950 Biberach Imidazo [4,5-b] pyridine, ihre Herstellung und ihre Verwendung als Cardiötonica
EP0011399A1 (en) * 1978-11-11 1980-05-28 FISONS plc N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them
DE2927988A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 8-phenyl-purine, deren herstellung und deren verwendung als arzneimittel
DE2927987A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
DE3037464A1 (de) * 1980-10-03 1982-05-19 Dr. Karl Thomae Gmbh, 7950 Biberach 6-hydroxy-2-phenyl-imidazo 4,5-b zu pyridine, ihre herstellung und diese sie enthaltende arzneimittel
DE3044497A1 (de) * 1980-11-26 1982-06-24 Dr. Karl Thomae Gmbh, 7950 Biberach Neues verfahren zur herstellung von imidazo(4,5-b)pyridinen und -pyrimidinen
GB2091249A (en) * 1980-12-23 1982-07-28 Fordonal Sa Xanthine derivatives
DE3273461D1 (en) * 1981-08-19 1986-10-30 Merck Patent Gmbh 2-arylimidazopyridines
ES517193A0 (es) * 1981-11-10 1983-12-01 Wellcome Found Un procedimiento para la preparacion de nuevos derivados de imidazo (4,5-c)piridina.
US4452788A (en) * 1982-04-21 1984-06-05 Warner-Lambert Company Substituted 8-phenylxanthines
ZA832938B (en) * 1982-05-03 1984-12-24 Lilly Co Eli 2-phenylimidazo(4,5-c)pyridines
DE3217583A1 (de) * 1982-05-11 1983-11-17 Merck Patent Gmbh, 6100 Darmstadt 2-aryl-tetraazaindene
DE3224512A1 (de) * 1982-07-01 1984-01-05 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
ES541662A0 (es) 1985-12-16
PT78836A (de) 1984-08-01
US4670438A (en) 1987-06-02
GR82380B (pt) 1984-12-13
FI842666A (fi) 1985-01-06
HU194878B (en) 1988-03-28
NZ208779A (en) 1988-02-29
ZA845103B (en) 1986-03-26
ES8506017A1 (es) 1985-06-16
AU3032384A (en) 1985-01-10
ES8603480A1 (es) 1985-12-16
IL72298A0 (en) 1984-11-30
EP0130461A2 (de) 1985-01-09
JPS6036486A (ja) 1985-02-25
HUT34475A (en) 1985-03-28
EP0130461A3 (de) 1987-05-06
DD224851A5 (de) 1985-07-17
PT78836B (de) 1986-10-21
FI842666A0 (fi) 1984-07-03
NO842684L (no) 1985-01-07
ES533995A0 (es) 1985-06-16
ES541660A0 (es) 1985-12-16
KR850001208A (ko) 1985-03-16
ES541661A0 (es) 1985-12-16
DK326484D0 (da) 1984-07-03
DE3324115A1 (de) 1985-01-17
US4766130A (en) 1988-08-23
PH21496A (en) 1987-11-10
ES8603478A1 (es) 1985-12-16
ES8603479A1 (es) 1985-12-16

Similar Documents

Publication Publication Date Title
DK577084A (da) 2,2'iminobisethanol-derivater og fremgangsmaade til fremstilling deraf
DK326484D0 (da) Imidazoler, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne
NO855135L (no) Modifisert polyolefin og fremgangsmaate til fremstilling derav.
DK187687A (da) Fungicide forbindelser og fremgangsmaade til fremstilling deraf, midler indeholdende forbindelserne og disses anvendelse
DK161327C (da) Substituerede 2-piperazinopteridiner, fremgangsmaade til fremstilling deraf samt laegemidler indeholdende forbindelserne
DK210483A (da) Pyrogallolderivater, deres anvendelse og fremgangsmaade til fremstilling deraf
DK518687A (da) Imidazo-benzoxazinoner, deres fremstilling og laegemidler indholdende forbindelserne
DK5884A (da) Antibiotisk virksom forbindelse, fremgangsmaade til fremstilling deraf og praeparat indeholdende forbindelsen
NO822391L (no) Karbostyrilforbindelser, preparater inneholdende disse og fremgangsmaater for fremstilling av forbindelsene
DK160150C (da) Benzothiazinderivater, fremgangsmaade til fremstilling heraf og farmaceutiske praeparater indeholdende samme
DK572183A (da) 7-carboxymethoxyphenylacetamido-3-cephemderivater, fremgangsmaade til fremstilling deraf og antibakterielle praeparater indeholdende forbindelserne
DK451588A (da) Heterocycliske forbindelser, deres fremstilling og laegemidler indeholdende forbindelserne
DK162221C (da) Cinnolinforbindelser, fremgangsmaade til fremstilling deraf og farmaceutiske midler indeholdende forbindelserne
DK435588D0 (da) Aralkylaminoalkoxyphenylderivater, fremgangsmaade til deres fremstilling og midler indeholdende disse
DK48482A (da) Azopigmentpraeparater,fremgangsmaade til deres fremstilling og deres anvendelse
DK157083D0 (da) Carbapenem-derivater og fremgangsmade til fremstilling deraf
DK442383D0 (da) Carbapenem-derivater og fremgangsmade til fremstilling deraf
DK572785A (da) Imidazolderivater, laegemidler indeholdende disse forbindelser og fremgangsmaader til deres fremstilling
DK442183A (da) Thiatriazin-derivater, fremgangsmaader til fremstilling deraf og deres anvendelse som laegemidler
DE3381733D1 (de) Gelpraeparate zur externen applikation.
NO833369L (no) Heterocykliske forbindelser, fremgangsmaate til fremstilling derav og preparat inneholdende slike forbindelser
DK161687A (da) Hydroquinolinderivater, fremgangsmaade til fremstilling deraf og laegemidler indeholdende disse derivater.
DK155983A (da) Carbapenem-derivater og fremgangsmaade til fremstilling deraf
DK513784A (da) Iodacetamider, deres fremstilling og anvendelse til skadedyrsbekaempelse
DK1384A (da) Dibenzocycloheptenyliden-forbindelser og fremgangsmaade til deres fremstilling

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment