DK3172317T3 - Fremgangsmåde til oprensning af poliovirus fra cellekulturer - Google Patents

Fremgangsmåde til oprensning af poliovirus fra cellekulturer Download PDF

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Publication number
DK3172317T3
DK3172317T3 DK15741534.0T DK15741534T DK3172317T3 DK 3172317 T3 DK3172317 T3 DK 3172317T3 DK 15741534 T DK15741534 T DK 15741534T DK 3172317 T3 DK3172317 T3 DK 3172317T3
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Denmark
Prior art keywords
poliovirus
cleaning
procedure
cell cultures
cultures
Prior art date
Application number
DK15741534.0T
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English (en)
Inventor
Mariken Segers
Nfor Beckley Kungah
Feras Nachmi Alazi
Vocht Marcel Leo De
Original Assignee
Janssen Vaccines & Prevention Bv
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Publication date
Application filed by Janssen Vaccines & Prevention Bv filed Critical Janssen Vaccines & Prevention Bv
Application granted granted Critical
Publication of DK3172317T3 publication Critical patent/DK3172317T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32311Enterovirus
    • C12N2770/32351Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32611Poliovirus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32611Poliovirus
    • C12N2770/32651Methods of production or purification of viral material
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DK15741534.0T 2014-07-24 2015-07-21 Fremgangsmåde til oprensning af poliovirus fra cellekulturer DK3172317T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14178392 2014-07-24
EP14178399 2014-07-24
PCT/EP2015/066638 WO2016012445A2 (en) 2014-07-24 2015-07-21 Process for the purification of poliovirus from cell cultures

Publications (1)

Publication Number Publication Date
DK3172317T3 true DK3172317T3 (da) 2019-07-22

Family

ID=53719768

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15741534.0T DK3172317T3 (da) 2014-07-24 2015-07-21 Fremgangsmåde til oprensning af poliovirus fra cellekulturer

Country Status (14)

Country Link
US (1) US10294460B2 (da)
EP (1) EP3172317B1 (da)
JP (1) JP6385559B2 (da)
KR (1) KR102364111B1 (da)
CN (1) CN106574252B (da)
AU (1) AU2015294014B2 (da)
BR (1) BR112017001177B1 (da)
CA (1) CA2955877A1 (da)
DK (1) DK3172317T3 (da)
EA (1) EA034503B1 (da)
ES (1) ES2733489T3 (da)
PL (1) PL3172317T3 (da)
SG (1) SG11201700361QA (da)
WO (1) WO2016012445A2 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3172317B1 (en) 2014-07-24 2019-05-01 Janssen Vaccines & Prevention B.V. Process for the purification of poliovirus from cell cultures
US10954492B2 (en) 2015-06-10 2021-03-23 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Processes for production and purification of nucleic acid-containing compositions
MX2019002495A (es) * 2016-09-01 2020-02-17 Takeda Vaccines Inc Metodos para producir virus para la produccion de vacunas.
EP3749757A4 (en) * 2018-02-07 2021-11-24 Bharat Biotech International Limited PROCESS FOR PURIFICATION AND INACTIVATION OF ENTERVIRUSES AND VACCINE COMPOSITIONS OBTAINED THEREOF
US20240043813A1 (en) * 2020-12-17 2024-02-08 Merck Sharp & Dohme Llc Enterovirus purification with cation exchange chromatography
JP2023141423A (ja) * 2022-03-24 2023-10-05 国立大学法人 東京大学 ウイルスの精製方法
CN118598954A (zh) * 2023-03-06 2024-09-06 康希诺生物股份公司 一种纯化病毒样颗粒的方法和用途
CN116987676B (zh) * 2023-09-27 2023-12-19 深圳源兴基因技术有限公司 一种微载体痘病毒高效培养方法

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US4525349A (en) 1981-12-29 1985-06-25 Societe Anonyme Dite: Institut Merueux Process for the large-scale production of a vaccine against poliomyelitis and the resulting vaccine
ATE445705T1 (de) 1995-06-15 2009-10-15 Crucell Holland Bv Verpackungssysteme für humane rekombinante adenoviren zur gentherapie
GB0002661D0 (en) 2000-02-04 2000-03-29 Biomade B V Method of stabilizing a hydrophobin-containing solution and a method of coating a surface with a hydrophobin
EP1370643A1 (en) 2001-03-16 2003-12-17 Oncolytics Biotech, Inc. Method of extracting virus from cell culture
ES2285120T3 (es) 2002-05-14 2007-11-16 MERCK & CO., INC. Procedimientos de purificacion de adenovirus.
CN1777622A (zh) * 2003-02-24 2006-05-24 施里昂药品股份公司 脊髓灰质炎病毒受体功能的调节
EP2166091A3 (en) * 2003-03-10 2015-06-10 Novozymes A/S Alcohol product processes
EP1613729A1 (en) 2003-04-04 2006-01-11 Novozymes A/S Mash viscosity reduction
JP2004313019A (ja) 2003-04-11 2004-11-11 Mitsubishi Kagaku Iatron Inc 組織抽出液の製造方法
CN100383238C (zh) 2003-05-09 2008-04-23 克鲁塞尔荷兰公司 E1-永生化的细胞培养物及培养所述细胞以提高从中获取的产物产量的方法
CN1922308A (zh) * 2004-02-23 2007-02-28 克鲁塞尔荷兰公司 病毒纯化方法
CN104388324A (zh) 2004-03-05 2015-03-04 帝斯曼知识产权资产管理有限公司 用于通过连续灌注和交互切向流来培养细胞的方法
MX2007002372A (es) 2004-08-27 2007-05-08 Panacea Biotec Ltd Vacuna para la poliomielitis inactivada derivada de la cepa sabin del virus de la polio.
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
CA2602944C (en) * 2005-04-11 2015-08-11 Crucell Holland B.V. Virus purification using ultrafiltration
US7968318B2 (en) 2006-06-06 2011-06-28 Genencor International, Inc. Process for conversion of granular starch to ethanol
DK2634242T3 (da) 2006-07-14 2017-05-22 Patheon Holdings I B V Forbedret fremgangsmåde til dyrkning af celler
PE20120571A1 (es) 2009-07-16 2012-06-06 Crucell Holland Bv Produccion de titulos elevados de polivirus para la produccion de vacunas
CN102791852B (zh) * 2009-10-15 2014-05-07 克鲁塞尔荷兰公司 纯化腺病毒颗粒的方法
KR101805938B1 (ko) * 2009-10-15 2018-01-10 얀센 백신스 앤드 프리벤션 비.브이. 고밀도 세포 배양액에서 아데노바이러스의 정제 방법
EP2461162A1 (en) * 2010-12-03 2012-06-06 Texcell, . Method for determining the titre of viruses by using infectious standards
WO2012168003A1 (en) 2011-06-06 2012-12-13 Biocartis S.A. Selective lysis of cells by ionic surfactants
EP3172317B1 (en) 2014-07-24 2019-05-01 Janssen Vaccines & Prevention B.V. Process for the purification of poliovirus from cell cultures

Also Published As

Publication number Publication date
AU2015294014A1 (en) 2017-01-12
KR102364111B1 (ko) 2022-02-17
WO2016012445A3 (en) 2016-03-31
EP3172317A2 (en) 2017-05-31
SG11201700361QA (en) 2017-02-27
JP2017524360A (ja) 2017-08-31
WO2016012445A2 (en) 2016-01-28
EA034503B1 (ru) 2020-02-14
US10294460B2 (en) 2019-05-21
BR112017001177A2 (pt) 2017-11-21
JP6385559B2 (ja) 2018-09-05
ES2733489T3 (es) 2019-11-29
CN106574252A (zh) 2017-04-19
US20170166872A1 (en) 2017-06-15
CN106574252B (zh) 2021-06-01
PL3172317T3 (pl) 2019-10-31
CA2955877A1 (en) 2016-01-28
BR112017001177B1 (pt) 2022-05-24
EP3172317B1 (en) 2019-05-01
AU2015294014B2 (en) 2018-08-23
KR20170031242A (ko) 2017-03-20
EA201790250A1 (ru) 2017-05-31

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