DK3123151T3 - LUMINESCENT OXYGEN CHANNELING IMMUNOASSAY USING THREE ANTIBODIES AND METHODS FOR PRODUCING AND USING THEREOF - Google Patents
LUMINESCENT OXYGEN CHANNELING IMMUNOASSAY USING THREE ANTIBODIES AND METHODS FOR PRODUCING AND USING THEREOF Download PDFInfo
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- DK3123151T3 DK3123151T3 DK15767906.9T DK15767906T DK3123151T3 DK 3123151 T3 DK3123151 T3 DK 3123151T3 DK 15767906 T DK15767906 T DK 15767906T DK 3123151 T3 DK3123151 T3 DK 3123151T3
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- antibody
- binding fragment
- analyte
- binding
- epitope
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- 125000001424 substituent group Chemical group 0.000 description 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
- YRHRIQCWCFGUEQ-UHFFFAOYSA-N thioxanthen-9-one Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3SC2=C1 YRHRIQCWCFGUEQ-UHFFFAOYSA-N 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- PBYZMCDFOULPGH-UHFFFAOYSA-N tungstate Chemical compound [O-][W]([O-])(=O)=O PBYZMCDFOULPGH-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461970596P | 2014-03-26 | 2014-03-26 | |
| PCT/US2015/022209 WO2015148479A1 (en) | 2014-03-26 | 2015-03-24 | Luminescent oxygen channeling immunoassay utilizing three antibodies and methods of production and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3123151T3 true DK3123151T3 (en) | 2019-03-18 |
Family
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| DK15767906.9T DK3123151T3 (en) | 2014-03-26 | 2015-03-24 | LUMINESCENT OXYGEN CHANNELING IMMUNOASSAY USING THREE ANTIBODIES AND METHODS FOR PRODUCING AND USING THEREOF |
| DK18199087.0T DK3483593T3 (da) | 2014-03-26 | 2015-03-24 | Luminescent-oxygen-channeling-immunoassay ved anvendelse af tre antistoffer og fremgangsmåder til fremstilling og anvendelse deraf |
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| DK18199087.0T DK3483593T3 (da) | 2014-03-26 | 2015-03-24 | Luminescent-oxygen-channeling-immunoassay ved anvendelse af tre antistoffer og fremgangsmåder til fremstilling og anvendelse deraf |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20170176419A1 (https=) |
| EP (2) | EP3123151B1 (https=) |
| JP (1) | JP6596440B2 (https=) |
| CN (1) | CN106662532B (https=) |
| AU (1) | AU2015236288A1 (https=) |
| CA (1) | CA2942281C (https=) |
| DK (2) | DK3123151T3 (https=) |
| ES (2) | ES2713428T3 (https=) |
| IL (1) | IL247630A0 (https=) |
| MX (1) | MX377772B (https=) |
| WO (1) | WO2015148479A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2018107012A1 (en) | 2016-12-09 | 2018-06-14 | Abbott Point Of Care Inc. | Crossover analytical systems and methods using an immunosensor and magnetic immunosensor |
| US10928388B2 (en) | 2016-12-09 | 2021-02-23 | Abbott Point Of Care Inc. | Combined immunoassay and magnetic immunoassay methods for extended range of sensitivity |
| US10935511B2 (en) | 2016-12-09 | 2021-03-02 | Abbott Point Of Care Inc. | Ameliorated crosstalk immunoassay test device for determining a concentration of an analyte |
| EP3552016A1 (en) | 2016-12-09 | 2019-10-16 | Abbott Point of Care Inc. | Extended range immunoassay devices with immunosensor and magnetic immunosensor |
| US10514379B2 (en) * | 2016-12-09 | 2019-12-24 | Abbott Point Of Care Inc. | Dual range cardiac troponin immunoassay devices and methods using immunosensor and magnetic immunosensor |
| WO2018107007A1 (en) | 2016-12-09 | 2018-06-14 | Abbott Point Of Care Inc. | Combined immunoassay and magnetic immunoassay systems and devices for extended range of sensitivity |
| WO2019167128A1 (ja) * | 2018-02-27 | 2019-09-06 | 株式会社 島津製作所 | サンドイッチ型免疫測定法 |
| JP7434144B2 (ja) * | 2018-02-27 | 2024-02-20 | 株式会社島津製作所 | ＡＰＰ６６９－ｘのＮ末端を特異的に認識する抗体、及び免疫測定法 |
| US12140596B2 (en) | 2018-07-30 | 2024-11-12 | Siemens Healthcare Diagnostics Inc. | Kits, microfluidics devices, and methods for performing biotin assays |
| WO2020068548A1 (en) * | 2018-09-25 | 2020-04-02 | Siemens Healthcare Diagnostics Inc. | Compositions, kits, and methods for multiplex assays to correct for biotin interference in target analyte measurements |
| WO2021041607A1 (en) * | 2019-08-29 | 2021-03-04 | Siemens Healthcare Diagnostics Inc. | Device and method to evaluate a fluid sample on a single-use multianalyte consumable |
| CN113125416B (zh) * | 2019-12-31 | 2025-08-22 | 科美博阳诊断技术(上海)有限公司 | 一种竞争性均相化学发光检测方法及其应用 |
| CN113125704B (zh) * | 2019-12-31 | 2025-08-22 | 科美博阳诊断技术(上海)有限公司 | 一种均相化学发光测定试剂盒及其应用 |
| CN113125418A (zh) * | 2019-12-31 | 2021-07-16 | 科美诊断技术股份有限公司 | 一种均相化学发光检测方法及其应用 |
| CN113125706B (zh) * | 2019-12-31 | 2025-07-08 | 科美博阳诊断技术(上海)有限公司 | 一种竞争性均相化学发光测定试剂盒及其应用 |
| CN113125415B (zh) * | 2019-12-31 | 2025-08-22 | 科美博阳诊断技术(上海)有限公司 | 一种竞争性均相化学发光检测方法及其应用 |
| CN113125731B (zh) * | 2019-12-31 | 2025-09-16 | 科美博阳诊断技术(上海)有限公司 | 一种竞争性均相化学发光测定试剂盒及其应用 |
| US20230152336A1 (en) * | 2020-04-24 | 2023-05-18 | Siemens Healthcare Diagnostics Inc. | Calibration and quality control reagents for use with immunoassays for antibodies and methods of production and use thereof |
| CN111781385B (zh) * | 2020-08-19 | 2023-07-18 | 武汉生之源生物科技股份有限公司 | 一种NT-proBNP检测试剂盒及其制备方法 |
| CN114544978A (zh) * | 2022-03-04 | 2022-05-27 | 美康生物科技股份有限公司 | 一种igf-1检测试剂盒及其制备方法和检测方法 |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| NO164622C (no) * | 1988-05-11 | 1990-10-24 | Tore Lindmo | Binaer immunometrisk partikkelbasert metode for maaling av spesifikke serum-antigener ved hjelp av vaeskestroemsmikrofotometri og et ferdigpreparert maaloppsett derav. |
| EP0542810A1 (en) | 1990-08-02 | 1993-05-26 | B.R. Centre Limited | Methods for the production of proteins with a desired function |
| EP0984281B1 (en) * | 1991-05-22 | 2007-01-03 | Dade Behring Marburg GmbH | A homogeneous assay for determining analyte |
| US5340716A (en) | 1991-06-20 | 1994-08-23 | Snytex (U.S.A.) Inc. | Assay method utilizing photoactivated chemiluminescent label |
| US6251581B1 (en) * | 1991-05-22 | 2001-06-26 | Dade Behring Marburg Gmbh | Assay method utilizing induced luminescence |
| GB9326238D0 (en) * | 1993-12-23 | 1994-02-23 | Sinvent As | Method of assay |
| US7285418B2 (en) * | 1996-06-25 | 2007-10-23 | Hytest Ltd. | Method and kit for the diagnosis of troponin I |
| US6248546B1 (en) * | 1998-03-09 | 2001-06-19 | Diagnostic Systems Laboratories, Inc. | Assay of IGFBP complex |
| US6703248B1 (en) * | 1999-12-15 | 2004-03-09 | Dade Behring Marburg Gmbh | Particles for diagnostic and therapeutic use |
| DE10064827A1 (de) * | 2000-12-22 | 2002-06-27 | Dade Behring Marburg Gmbh | Nachweisverfahren |
| US6551788B1 (en) * | 2001-11-28 | 2003-04-22 | Beckman Coulter, Inc. | Particle-based ligand assay with extended dynamic range |
| US6764819B2 (en) * | 2002-07-16 | 2004-07-20 | Emp Biotech Gmbh | Method for chemiluminescent detection |
| DE112004001863T5 (de) * | 2003-10-03 | 2006-09-07 | Scantibodies Laboratory, Inc., Santee | Verfahren und Verwendung von Bindungskomponenten zur Verbesserung der Testspezifität |
| EP1794282A4 (en) * | 2004-09-20 | 2011-03-23 | Boston Microfluidics | MICROFLUIDIC DEVICE FOR DETECTION OF SOLUBLE MOLECULES |
| US20060263907A1 (en) * | 2005-04-29 | 2006-11-23 | Zweig Stephen E | Fluorescence lateral flow immunoassay |
| US8124015B2 (en) * | 2006-02-03 | 2012-02-28 | Institute For Systems Biology | Multiplexed, microfluidic molecular assay device and assay method |
| GB2436616A (en) * | 2006-03-29 | 2007-10-03 | Inverness Medical Switzerland | Assay device and method |
| DK2064549T3 (da) * | 2006-09-21 | 2013-02-04 | Nestec Sa | Antistof-baserede arrays til detektion af flere signaltransducere i sjældne cirkulerende celler |
| CN101675075B (zh) * | 2007-03-01 | 2014-06-18 | 西福根有限公司 | 重组抗表皮生长因子受体抗体组合物 |
| US7790401B2 (en) * | 2007-08-06 | 2010-09-07 | Siemens Healthcare Diagnostics | Methods for detection of immunosuppressant drugs |
| US20090170218A1 (en) * | 2008-01-02 | 2009-07-02 | Dade Behring Inc. | Methods for detection of cyclosporin a |
| WO2011087813A2 (en) * | 2009-12-22 | 2011-07-21 | University Of Washington | Capillarity-based devices for performing chemical processes and associated systems and methods |
| US9678068B2 (en) * | 2010-03-01 | 2017-06-13 | Quanterix Corporation | Ultra-sensitive detection of molecules using dual detection methods |
| US10088490B2 (en) * | 2010-08-20 | 2018-10-02 | Siemens Healthcare Diagnostics Inc. | Assay for analytes using multiple receptors |
| CN102565381B (zh) * | 2010-12-08 | 2014-06-18 | 中国科学院生态环境研究中心 | 导电微粒子介导电化学发光信号的免疫检测方法 |
| JP6226872B2 (ja) | 2011-11-22 | 2017-11-08 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． | キャリブレーションおよび／またはクオリティ・コントロール溶液として再構成用の乾燥試薬を含むデバイスとその製造および使用方法 |
| WO2014152165A1 (en) * | 2013-03-15 | 2014-09-25 | Siemens Healthcare Diagnostics Inc. | Luminescent oxygen channeling immunoassays utilizing electrochemical discharge of singlet oxygen and methods of production and use thereof |
| DK2972245T3 (da) | 2013-03-15 | 2020-09-07 | Siemens Healthcare Diagnostics Inc | Heterogene luminescerende oxygenkanaliserende immunoassays |
| WO2014151590A1 (en) | 2013-03-15 | 2014-09-25 | Siemens Healthcare Diagnostics Inc. | Heterogeneous luminescent oxygen channeling immunoassays and methods of production and use thereof |
| WO2014151450A1 (en) | 2013-03-15 | 2014-09-25 | Siemens Healthcare Diagnostics Inc. | Microfluidic distributing device |
| CN105722859B (zh) * | 2013-07-25 | 2021-05-07 | 西托姆克斯治疗公司 | 多特异性抗体、多特异性可活化抗体及其使用方法 |
| US20160320415A1 (en) * | 2013-12-16 | 2016-11-03 | Xen Biofluidx, Inc. | Fast reconstituting reagent pellets |
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2015
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- 2015-03-24 DK DK15767906.9T patent/DK3123151T3/en active
- 2015-03-24 US US15/128,479 patent/US20170176419A1/en not_active Abandoned
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- 2015-03-24 EP EP15767906.9A patent/EP3123151B1/en active Active
- 2015-03-24 AU AU2015236288A patent/AU2015236288A1/en not_active Abandoned
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- 2015-03-24 ES ES18199087T patent/ES2884930T3/es active Active
- 2015-03-24 WO PCT/US2015/022209 patent/WO2015148479A1/en not_active Ceased
- 2015-03-24 JP JP2016557105A patent/JP6596440B2/ja active Active
- 2015-03-24 EP EP18199087.0A patent/EP3483593B1/en active Active
- 2015-03-24 CN CN201580024761.3A patent/CN106662532B/zh active Active
- 2015-03-24 DK DK18199087.0T patent/DK3483593T3/da active
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2021
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2025
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Also Published As
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| MX377772B (es) | 2025-03-11 |
| US20210231647A1 (en) | 2021-07-29 |
| CA2942281A1 (en) | 2015-10-01 |
| EP3123151A1 (en) | 2017-02-01 |
| EP3123151A4 (en) | 2017-03-22 |
| JP6596440B2 (ja) | 2019-10-23 |
| IL247630A0 (en) | 2016-11-30 |
| CN106662532B (zh) | 2019-12-13 |
| DK3483593T3 (da) | 2021-07-19 |
| ES2884930T3 (es) | 2021-12-13 |
| JP2017508971A (ja) | 2017-03-30 |
| AU2015236288A1 (en) | 2016-09-15 |
| EP3123151B1 (en) | 2018-11-28 |
| EP3483593A1 (en) | 2019-05-15 |
| CN106662532A (zh) | 2017-05-10 |
| ES2713428T3 (es) | 2019-05-21 |
| US20260104406A1 (en) | 2026-04-16 |
| US12366571B2 (en) | 2025-07-22 |
| CA2942281C (en) | 2023-03-14 |
| US20170176419A1 (en) | 2017-06-22 |
| MX2016011809A (es) | 2017-05-10 |
| WO2015148479A1 (en) | 2015-10-01 |
| EP3483593B1 (en) | 2021-04-28 |
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