DK2982352T3 - Cervikalt pessar indeholdende progesteron til forlænget, langvarig og kontinuerlig frigivelse, der anvendes til at forhindre for tidlige fødsler - Google Patents
Cervikalt pessar indeholdende progesteron til forlænget, langvarig og kontinuerlig frigivelse, der anvendes til at forhindre for tidlige fødsler Download PDFInfo
- Publication number
- DK2982352T3 DK2982352T3 DK14802800.4T DK14802800T DK2982352T3 DK 2982352 T3 DK2982352 T3 DK 2982352T3 DK 14802800 T DK14802800 T DK 14802800T DK 2982352 T3 DK2982352 T3 DK 2982352T3
- Authority
- DK
- Denmark
- Prior art keywords
- pessary
- progesterone
- cervical
- preterm birth
- preterm
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Reproductive Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Biological Depolymerization Polymers (AREA)
Claims (6)
1. Cervikalt pessar, kendetegnet ved, at det består af en dimethylsiloxanela-stomer omfattende progesteron homogent fordelt hen over pessarets legeme, I en mængde på fra 20 % til 30 % v/v af pessarets samlede vægt, en forlænget, langvarig og kontinuerlig frigivelse af progesteron i en periode på mindst 6 måneder, idet de opretholder deres intakte form hele tiden.
2. Cervikalt pessar ifølge krav 1, kendetegnet ved, at mængden af progesteron i pessaret er fra 5,0 g til 10,5 g.
3. Cervikalt pessar ifølge krav 1, kendetegnet ved, at det har en vægt på mellem 25 og 35 gram.
4. Cervikalt pessar ifølge krav 1, kendetegnet ved, at mængden af progesteron, som frigives langvarigt og kontinuerligt fra pessaret, er på 15 mg til 65 mg dagligt, i en periode på mindst 6 måneder.
5. Cervikalt pessar ifølge krav 1, kendetegnet ved, at elastomeren er dannet af vinyl-polydimethylsiloxanpolymer, amorft siliciumdioxid og platinkatalysator og en copolymer af dimethylmethylhydrogensiloxan med polydimethylsiloxan.
6. Cervikalt pessar ifølge krav 1 til 5, kendetegnet ved, at elastomeren er dannet af forhold mellem polymerer fra 6:1 til 14:1.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2014/062691 WO2015198104A1 (es) | 2014-06-28 | 2014-06-28 | Pesario de cerclaje que contiene progesterona de liberación prolongada, sostenida y continua, útil para la prevención de parto prematuro |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2982352T3 true DK2982352T3 (da) | 2018-11-26 |
Family
ID=54937437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14802800.4T DK2982352T3 (da) | 2014-06-28 | 2014-06-28 | Cervikalt pessar indeholdende progesteron til forlænget, langvarig og kontinuerlig frigivelse, der anvendes til at forhindre for tidlige fødsler |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9820994B2 (da) |
| EP (1) | EP2982352B1 (da) |
| JP (1) | JP6529583B2 (da) |
| KR (1) | KR20170021929A (da) |
| CN (1) | CN105392454B (da) |
| AR (2) | AR098604A1 (da) |
| BR (1) | BR112014030232A2 (da) |
| CA (1) | CA2873222A1 (da) |
| CR (1) | CR20160604A (da) |
| CY (1) | CY1121245T1 (da) |
| DK (1) | DK2982352T3 (da) |
| ES (1) | ES2699003T3 (da) |
| HR (1) | HRP20181794T1 (da) |
| HU (1) | HUE040176T2 (da) |
| LT (1) | LT2982352T (da) |
| MX (1) | MX368212B (da) |
| PL (1) | PL2982352T3 (da) |
| PT (1) | PT2982352T (da) |
| SI (1) | SI2982352T1 (da) |
| WO (1) | WO2015198104A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102110132B1 (ko) * | 2017-10-27 | 2020-05-13 | 고려대학교산학협력단 | 자궁경부 무력증에서 조산을 방지하기 위한 자궁경부 밴드 구조체 |
| US11497647B2 (en) | 2018-04-24 | 2022-11-15 | Emory University | Anatomical support systems, devices, and related methods |
| US11311409B2 (en) | 2018-05-19 | 2022-04-26 | Ashley Camille CRAFTON | Hannah cervical cup |
| US11872395B2 (en) | 2019-06-18 | 2024-01-16 | Obstetric Solutions, Llc | Pessary device and methods for preventing premature births |
| US12011602B2 (en) | 2019-06-18 | 2024-06-18 | Obstetric Solutions Llc | Wireless power for pessary device |
| EP4069248A4 (en) * | 2019-12-06 | 2024-01-03 | Prathima Chowdary | SUSTAINED RELEASE VAGINAL RING PESSARY FOR TREATMENT OF ATROPHY, CYSTITIS AND UTEROVAGINAL PROLAPSUS |
| KR102571791B1 (ko) * | 2021-03-22 | 2023-08-28 | 가톨릭대학교 산학협력단 | 산모 맞춤형 조산 예방용 페서리 및 이의 제조방법 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US415991A (en) | 1889-11-26 | zipernowsky | ||
| US3948254A (en) * | 1971-11-08 | 1976-04-06 | Alza Corporation | Novel drug delivery device |
| BE791632A (fr) * | 1971-11-20 | 1973-05-21 | Schering Ag | Supports a base de caoutchouc siliconique pour agents medicamenteux |
| DD114905A5 (da) * | 1973-12-06 | 1975-09-05 | ||
| DE2445971A1 (de) * | 1974-09-24 | 1976-04-08 | Schering Ag | Arzneimittelwirkstofftraeger ii |
| US4439432A (en) * | 1982-03-22 | 1984-03-27 | Peat Raymond F | Treatment of progesterone deficiency and related conditions with a stable composition of progesterone and tocopherols |
| JP2590358B2 (ja) * | 1988-03-01 | 1997-03-12 | 正雄 五十嵐 | 子宮内膜症治療用の子宮内又は膣内投与製剤 |
| GB9326255D0 (en) * | 1993-12-23 | 1994-02-23 | Roussel Lab Ltd | Medical device for the prevention and treatment of cancer |
| DE19606355A1 (de) * | 1996-02-12 | 1997-08-14 | Schering Ag | Kontrazeptive Freisetzungssysteme mit antiviraler und/oder antibakterieller Wirkung |
| FR2745180B1 (fr) * | 1996-02-23 | 1998-05-07 | Dow Corning Sa | Procede de fabrication de dispositifs a liberation controlee |
| US5869081A (en) | 1996-06-28 | 1999-02-09 | The Population Council | Progesterone vaginal ring for treatment of infertility |
| US5972372A (en) * | 1996-07-31 | 1999-10-26 | The Population Council, Inc. | Intravaginal rings with insertable drug-containing core |
| CN1184957C (zh) * | 1997-05-07 | 2005-01-19 | 盖伦(化学制品)有限公司 | 用于给药睾酮和睾酮前体的阴道内给药装置 |
| AU1300799A (en) * | 1997-11-03 | 1999-05-24 | Deschutes Medical Products, Inc. | Pessary with medicated cartridge |
| US6476079B1 (en) * | 1999-12-23 | 2002-11-05 | Leiras Oy | Devices for the delivery of drugs having antiprogestinic properties |
| US20050197651A1 (en) * | 2001-04-25 | 2005-09-08 | Chen Hai L. | Vaginal ring preparation and its application |
| US20040089308A1 (en) | 2002-11-13 | 2004-05-13 | Welch Robert A. | Cervical ring to deliver medication |
| US7833545B2 (en) | 2003-04-29 | 2010-11-16 | The General Hospital Corporation | Methods and devices for the sustained release of multiple drugs |
| ATE497745T1 (de) | 2004-07-09 | 2011-02-15 | Population Council Inc | Zusammensetzungen mit verzögerter freisetzung mit progesteron-rezeptormodulatoren |
| US8828981B2 (en) * | 2007-02-06 | 2014-09-09 | George Creasy | Progesterone for the treatment or prevention of spontaneous preterm birth |
| EP2359807B1 (en) * | 2008-02-04 | 2017-07-26 | Ferring B.V. | Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof |
| FI20085277A0 (fi) * | 2008-04-02 | 2008-04-02 | Bayer Schering Pharma Oy | Kohdunsisäinen järjestelmä |
| ES2626156T3 (es) | 2009-07-21 | 2017-07-24 | The Population Council, Inc. | Anillo vaginal de gradiente multicapa |
| CN103025320A (zh) * | 2010-03-28 | 2013-04-03 | 伊万斯彻有限公司 | 阴道内药物递送装置 |
| US8580294B2 (en) * | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
| EP2717813B1 (en) * | 2011-06-06 | 2020-05-20 | Auritec Pharmaceuticals | Drug delivery device employing wicking release window |
| AR089765A1 (es) * | 2012-01-23 | 2014-09-17 | Bayer Oy | Un sistema para el suministro de un farmaco |
| DE102012009057A1 (de) | 2012-05-09 | 2013-11-14 | Dr. Arabin GmbH & Co. KG | Rotationspessar mit zusätzlicher Wirkstoffkomponente |
-
2014
- 2014-06-28 PL PL14802800T patent/PL2982352T3/pl unknown
- 2014-06-28 DK DK14802800.4T patent/DK2982352T3/da active
- 2014-06-28 CR CR20160604A patent/CR20160604A/es unknown
- 2014-06-28 HU HUE14802800A patent/HUE040176T2/hu unknown
- 2014-06-28 BR BR112014030232A patent/BR112014030232A2/pt not_active Application Discontinuation
- 2014-06-28 WO PCT/IB2014/062691 patent/WO2015198104A1/es active Application Filing
- 2014-06-28 CA CA2873222A patent/CA2873222A1/en not_active Abandoned
- 2014-06-28 LT LTEP14802800.4T patent/LT2982352T/lt unknown
- 2014-06-28 CN CN201480001890.6A patent/CN105392454B/zh not_active Expired - Fee Related
- 2014-06-28 KR KR1020147034262A patent/KR20170021929A/ko not_active Application Discontinuation
- 2014-06-28 JP JP2017520021A patent/JP6529583B2/ja not_active Expired - Fee Related
- 2014-06-28 MX MX2014014769A patent/MX368212B/es active IP Right Grant
- 2014-06-28 SI SI201430975T patent/SI2982352T1/sl unknown
- 2014-06-28 PT PT14802800T patent/PT2982352T/pt unknown
- 2014-06-28 EP EP14802800.4A patent/EP2982352B1/en not_active Not-in-force
- 2014-06-28 ES ES14802800T patent/ES2699003T3/es active Active
- 2014-06-28 US US14/405,037 patent/US9820994B2/en not_active Expired - Fee Related
- 2014-12-03 AR ARP140104501A patent/AR098604A1/es unknown
-
2018
- 2018-10-30 HR HRP20181794TT patent/HRP20181794T1/hr unknown
- 2018-12-03 CY CY20181101285T patent/CY1121245T1/el unknown
-
2020
- 2020-01-22 AR ARP200100164A patent/AR122434A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CR20160604A (es) | 2017-03-10 |
| KR20170021929A (ko) | 2017-03-02 |
| AR122434A2 (es) | 2022-09-14 |
| EP2982352B1 (en) | 2018-10-03 |
| CY1121245T1 (el) | 2020-05-29 |
| JP2017524030A (ja) | 2017-08-24 |
| US9820994B2 (en) | 2017-11-21 |
| PL2982352T3 (pl) | 2019-01-31 |
| PT2982352T (pt) | 2018-11-29 |
| LT2982352T (lt) | 2018-11-12 |
| SI2982352T1 (sl) | 2018-12-31 |
| CN105392454A (zh) | 2016-03-09 |
| HUE040176T2 (hu) | 2019-02-28 |
| MX368212B (es) | 2019-09-24 |
| BR112014030232A2 (pt) | 2017-06-27 |
| EP2982352A1 (en) | 2016-02-10 |
| ES2699003T3 (es) | 2019-02-06 |
| EP2982352A4 (en) | 2017-06-14 |
| HRP20181794T1 (hr) | 2018-12-28 |
| JP6529583B2 (ja) | 2019-06-12 |
| MX2014014769A (es) | 2016-03-30 |
| CA2873222A1 (en) | 2015-12-28 |
| WO2015198104A1 (es) | 2015-12-30 |
| AR098604A1 (es) | 2016-06-01 |
| US20160250229A1 (en) | 2016-09-01 |
| CN105392454B (zh) | 2018-05-08 |
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