DK2970412T5 - Aktivering af bioluminescens via strukturel komplementering - Google Patents

Aktivering af bioluminescens via strukturel komplementering Download PDF

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Publication number
DK2970412T5
DK2970412T5 DK14769752.8T DK14769752T DK2970412T5 DK 2970412 T5 DK2970412 T5 DK 2970412T5 DK 14769752 T DK14769752 T DK 14769752T DK 2970412 T5 DK2970412 T5 DK 2970412T5
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DK
Denmark
Prior art keywords
bioluminescence
activation
via structural
structural complementation
complementation
Prior art date
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DK14769752.8T
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Danish (da)
English (en)
Other versions
DK2970412T3 (da
Inventor
Lance Encell
Mary Hall
Keith Wood
Monika Wood
Marie Schwinn
Brock F Binkowski
Hicham Zegzouti
Nidhi Nath
Subhanjan Mondal
Said Goueli
Thomas Kirkland
James Unch
Melanie Dart
Andrew S Dixon
Poncho Meisenheimer
Dileep K Pulukkunat
Matthew Robers
Thomas Machleidt
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Promega Corp
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Publication of DK2970412T3 publication Critical patent/DK2970412T3/da
Publication of DK2970412T5 publication Critical patent/DK2970412T5/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43509—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q30/00—Commerce
    • G06Q30/02—Marketing; Price estimation or determination; Fundraising
    • G06Q30/0283—Price estimation or determination
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q30/00—Commerce
    • G06Q30/06—Buying, selling or leasing transactions
    • G06Q30/0601—Electronic shopping [e-shopping]
    • G06Q30/0631—Recommending goods or services
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04W—WIRELESS COMMUNICATION NETWORKS
    • H04W4/00—Services specially adapted for wireless communication networks; Facilities therefor
    • H04W4/02—Services making use of location information
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04W—WIRELESS COMMUNICATION NETWORKS
    • H04W4/00—Services specially adapted for wireless communication networks; Facilities therefor
    • H04W4/30—Services specially adapted for particular environments, situations or purposes
    • H04W4/35—Services specially adapted for particular environments, situations or purposes for the management of goods or merchandise
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04W—WIRELESS COMMUNICATION NETWORKS
    • H04W4/00—Services specially adapted for wireless communication networks; Facilities therefor
    • H04W4/30—Services specially adapted for particular environments, situations or purposes
    • H04W4/38—Services specially adapted for particular environments, situations or purposes for collecting sensor information
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Business, Economics & Management (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Development Economics (AREA)
  • Finance (AREA)
  • Accounting & Taxation (AREA)
  • General Engineering & Computer Science (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Signal Processing (AREA)
  • Strategic Management (AREA)
  • General Business, Economics & Management (AREA)
  • Economics (AREA)
  • Theoretical Computer Science (AREA)
  • Marketing (AREA)
  • Epidemiology (AREA)
DK14769752.8T 2013-03-15 2014-03-13 Aktivering af bioluminescens via strukturel komplementering DK2970412T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361791549P 2013-03-15 2013-03-15
PCT/US2014/026354 WO2014151736A1 (en) 2013-03-15 2014-03-13 Activation of bioluminescence by structural complementation

Publications (2)

Publication Number Publication Date
DK2970412T3 DK2970412T3 (da) 2022-08-29
DK2970412T5 true DK2970412T5 (da) 2024-10-14

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DK14769752.8T DK2970412T5 (da) 2013-03-15 2014-03-13 Aktivering af bioluminescens via strukturel komplementering
DK20197758.4T DK3783011T5 (da) 2013-03-15 2014-03-13 Aktivering af bioluminescens via strukturel komplementering

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Country Link
US (11) US9797890B2 (cg-RX-API-DMAC7.html)
EP (4) EP4177261A1 (cg-RX-API-DMAC7.html)
JP (4) JP6654557B2 (cg-RX-API-DMAC7.html)
KR (3) KR20230079494A (cg-RX-API-DMAC7.html)
CN (2) CN117024548A (cg-RX-API-DMAC7.html)
AU (3) AU2014236949C1 (cg-RX-API-DMAC7.html)
BR (1) BR112015023394B8 (cg-RX-API-DMAC7.html)
CA (1) CA2906063C (cg-RX-API-DMAC7.html)
DK (2) DK2970412T5 (cg-RX-API-DMAC7.html)
ES (2) ES2926463T3 (cg-RX-API-DMAC7.html)
IL (3) IL286816B (cg-RX-API-DMAC7.html)
PL (2) PL2970412T3 (cg-RX-API-DMAC7.html)
PT (2) PT3783011T (cg-RX-API-DMAC7.html)
SG (2) SG10201601929YA (cg-RX-API-DMAC7.html)
WO (1) WO2014151736A1 (cg-RX-API-DMAC7.html)

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SG10201601929YA (en) 2016-04-28
ES2929362T3 (es) 2022-11-28
AU2020213288A1 (en) 2020-08-27
CA2906063C (en) 2025-10-07
US11493504B2 (en) 2022-11-08
PT2970412T (pt) 2022-09-13
CA2906063A1 (en) 2014-09-25
US12366572B2 (en) 2025-07-22
IL286816A (en) 2021-10-31
EP2970412B1 (en) 2022-08-10
ES2926463T3 (es) 2022-10-26
IL240985A0 (en) 2015-11-30
US10648971B2 (en) 2020-05-12
EP2970412A1 (en) 2016-01-20
BR112015023394B8 (pt) 2023-09-26
BR112015023394B1 (pt) 2023-08-29
US20180313825A1 (en) 2018-11-01
US10288605B2 (en) 2019-05-14
US9797890B2 (en) 2017-10-24
EP2970412A4 (en) 2016-07-27
US20140363375A1 (en) 2014-12-11
US20180196038A1 (en) 2018-07-12
PL3783011T3 (pl) 2022-11-21
AU2018256548A1 (en) 2018-11-22
EP3783011A1 (en) 2021-02-24
US10184936B2 (en) 2019-01-22
IL286816B (en) 2022-09-01
PL2970412T3 (pl) 2022-11-14
JP2024167207A (ja) 2024-12-03
JP2020097597A (ja) 2020-06-25
KR20230079494A (ko) 2023-06-07
AU2014236949C1 (en) 2018-11-29
JP2023055734A (ja) 2023-04-18
US20160282340A1 (en) 2016-09-29
US10107800B2 (en) 2018-10-23
AU2018256548B2 (en) 2020-05-14
US20250045806A1 (en) 2025-02-06
KR20150129721A (ko) 2015-11-20
US9869670B2 (en) 2018-01-16
AU2014236949A1 (en) 2015-09-24
CN117024548A (zh) 2023-11-10
EP4177261A1 (en) 2023-05-10
JP6654557B2 (ja) 2020-02-26
EP3783011B1 (en) 2022-09-21
US20250022022A1 (en) 2025-01-16
IL273989A (en) 2020-05-31
DK3783011T5 (da) 2024-08-19
JP2016519065A (ja) 2016-06-30
US20180306782A1 (en) 2018-10-25
JP7280842B2 (ja) 2023-05-24
AU2020213288B2 (en) 2022-07-07
US12367513B2 (en) 2025-07-22
EP4169935A1 (en) 2023-04-26
US20200292534A1 (en) 2020-09-17
SG11201507306VA (en) 2015-10-29
BR112015023394A2 (pt) 2017-11-28
AU2014236949B2 (en) 2018-08-02
US20230342826A1 (en) 2023-10-26
US20180095074A1 (en) 2018-04-05
CN105143249A (zh) 2015-12-09
IL273989B (en) 2021-10-31
PT3783011T (pt) 2022-10-26
JP7532562B2 (ja) 2024-08-13
IL240985B (en) 2020-05-31
US20140348747A1 (en) 2014-11-27
WO2014151736A1 (en) 2014-09-25
US9797889B2 (en) 2017-10-24
DK3783011T3 (da) 2022-10-17
KR20210036422A (ko) 2021-04-02
KR102675860B1 (ko) 2024-06-20
DK2970412T3 (da) 2022-08-29

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