DK291890A - Pyrimidinnucleosider, fremgangsmaade til fremstilling deraf og pyrimidinderivater til anvendelse som mellemprodukter ved fremgangsmaaden samt farmaceutiske praeparater indeholdende pyrimidinnucleosiderne og anvendelse af disse til fremstilling af laegemidler til behandling af aids og infektioner af retrovirus - Google Patents

Pyrimidinnucleosider, fremgangsmaade til fremstilling deraf og pyrimidinderivater til anvendelse som mellemprodukter ved fremgangsmaaden samt farmaceutiske praeparater indeholdende pyrimidinnucleosiderne og anvendelse af disse til fremstilling af laegemidler til behandling af aids og infektioner af retrovirus Download PDF

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DK291890A
DK291890A DK291890A DK291890A DK291890A DK 291890 A DK291890 A DK 291890A DK 291890 A DK291890 A DK 291890A DK 291890 A DK291890 A DK 291890A DK 291890 A DK291890 A DK 291890A
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public
compounds
piratures
pyrimin
substate
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DK291890A
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DK291890D0 (da
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Karl Nils Gunnar Johansson
Hans C G Malmberg
Rolf Noreen
S Christer Sahlberg
Daniel D Sohn
Salo Gronowitz
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Medivir Ab
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK291890A 1988-06-10 1990-12-07 Pyrimidinnucleosider, fremgangsmaade til fremstilling deraf og pyrimidinderivater til anvendelse som mellemprodukter ved fremgangsmaaden samt farmaceutiske praeparater indeholdende pyrimidinnucleosiderne og anvendelse af disse til fremstilling af laegemidler til behandling af aids og infektioner af retrovirus DK291890A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8802173A SE8802173D0 (sv) 1988-06-10 1988-06-10 Pyrimidine derivatives
PCT/SE1989/000322 WO1989012061A1 (en) 1988-06-10 1989-06-07 Pyrimidine nucleosides and intermediates

Publications (2)

Publication Number Publication Date
DK291890D0 DK291890D0 (da) 1990-12-07
DK291890A true DK291890A (da) 1991-02-07

Family

ID=20372582

Family Applications (1)

Application Number Title Priority Date Filing Date
DK291890A DK291890A (da) 1988-06-10 1990-12-07 Pyrimidinnucleosider, fremgangsmaade til fremstilling deraf og pyrimidinderivater til anvendelse som mellemprodukter ved fremgangsmaaden samt farmaceutiske praeparater indeholdende pyrimidinnucleosiderne og anvendelse af disse til fremstilling af laegemidler til behandling af aids og infektioner af retrovirus

Country Status (20)

Country Link
US (2) US5440040A (el)
EP (2) EP0691333A2 (el)
JP (1) JP2851094B2 (el)
KR (1) KR900701815A (el)
AT (1) ATE136308T1 (el)
AU (1) AU637574B2 (el)
CA (1) CA1339313C (el)
DE (1) DE68926137T2 (el)
DK (1) DK291890A (el)
ES (1) ES2087090T3 (el)
FI (1) FI94643C (el)
GR (1) GR3020212T3 (el)
HU (1) HU211736B (el)
IE (1) IE62914B1 (el)
MY (1) MY109743A (el)
NO (1) NO175981C (el)
PH (1) PH27219A (el)
PT (1) PT90803B (el)
SE (1) SE8802173D0 (el)
WO (1) WO1989012061A1 (el)

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Also Published As

Publication number Publication date
FI94643B (fi) 1995-06-30
PH27219A (en) 1993-05-04
NO905300L (no) 1991-02-06
NO175981B (no) 1994-10-03
GR3020212T3 (en) 1996-09-30
EP0691333A2 (en) 1996-01-10
JPH03504969A (ja) 1991-10-31
WO1989012061A1 (en) 1989-12-14
EP0357571B1 (en) 1996-04-03
US5576429A (en) 1996-11-19
EP0357571A3 (en) 1990-06-13
JP2851094B2 (ja) 1999-01-27
DK291890D0 (da) 1990-12-07
PT90803B (pt) 1994-10-31
MY109743A (en) 1997-05-31
DE68926137T2 (de) 1996-11-14
ATE136308T1 (de) 1996-04-15
AU3750489A (en) 1990-01-05
KR900701815A (ko) 1990-12-04
PT90803A (pt) 1989-12-29
SE8802173D0 (sv) 1988-06-10
CA1339313C (en) 1997-08-19
NO175981C (no) 1995-01-11
IE62914B1 (en) 1995-03-08
US5440040A (en) 1995-08-08
HU894340D0 (en) 1991-08-28
AU637574B2 (en) 1993-06-03
HUT57230A (en) 1991-11-28
EP0691333A3 (el) 1996-02-14
NO905300D0 (no) 1990-12-07
EP0357571A2 (en) 1990-03-07
IE891816L (en) 1989-12-10
FI94643C (fi) 1995-10-10
FI906053A0 (fi) 1990-12-07
DE68926137D1 (de) 1996-05-09
ES2087090T3 (es) 1996-07-16
HU211736B (en) 1995-12-28

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