DK290286A - Imidazolidinforbindelse og fremgangsmaade til fremstilling deraf - Google Patents

Imidazolidinforbindelse og fremgangsmaade til fremstilling deraf Download PDF

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Publication number
DK290286A
DK290286A DK290286A DK290286A DK290286A DK 290286 A DK290286 A DK 290286A DK 290286 A DK290286 A DK 290286A DK 290286 A DK290286 A DK 290286A DK 290286 A DK290286 A DK 290286A
Authority
DK
Denmark
Prior art keywords
imidazolide
procedures
producing
connection
branched
Prior art date
Application number
DK290286A
Other languages
Danish (da)
English (en)
Other versions
DK290286D0 (da
Inventor
Mario Pinza
Ugo Pfeiffer
Carlo Farina
Silvano Banfi
Original Assignee
Isf Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isf Spa filed Critical Isf Spa
Publication of DK290286D0 publication Critical patent/DK290286D0/da
Publication of DK290286A publication Critical patent/DK290286A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK290286A 1985-06-21 1986-06-20 Imidazolidinforbindelse og fremgangsmaade til fremstilling deraf DK290286A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21234/85A IT1190378B (it) 1985-06-21 1985-06-21 Derivati pirrolidonici

Publications (2)

Publication Number Publication Date
DK290286D0 DK290286D0 (da) 1986-06-20
DK290286A true DK290286A (da) 1986-12-22

Family

ID=11178795

Family Applications (1)

Application Number Title Priority Date Filing Date
DK290286A DK290286A (da) 1985-06-21 1986-06-20 Imidazolidinforbindelse og fremgangsmaade til fremstilling deraf

Country Status (20)

Country Link
US (1) US4824861A (fi)
EP (1) EP0207681B1 (fi)
JP (1) JPS62461A (fi)
KR (1) KR930006766B1 (fi)
AT (1) ATE73821T1 (fi)
AU (1) AU587258B2 (fi)
CA (1) CA1284248C (fi)
DE (1) DE3684368D1 (fi)
DK (1) DK290286A (fi)
ES (2) ES8801201A1 (fi)
FI (1) FI82446C (fi)
GR (1) GR861577B (fi)
HU (1) HU196225B (fi)
IL (1) IL79136A (fi)
IT (1) IT1190378B (fi)
NO (1) NO168428C (fi)
NZ (1) NZ216550A (fi)
PH (1) PH22851A (fi)
PT (2) PT82815B (fi)
ZA (1) ZA864444B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209644B (it) * 1985-06-21 1989-08-30 Isf Spa Composti farmacologicamente attivi.
DK356288A (da) * 1987-07-30 1989-01-31 Lonza Ag Fremgangsmaade til fremstilling af n-((4-hydroxy-pyrrolidin-2-on-1-yl)-acetyl)-glycinamid
HUT53607A (en) * 1989-01-17 1990-11-28 Hoffmann La Roche Process for production of derivatives of cyclohexan-acetamid
CH680293A5 (fi) * 1990-06-26 1992-07-31 Lonza Ag
US6229011B1 (en) * 1997-08-22 2001-05-08 Hoffman-La Roche Inc. N-aroylphenylalanine derivative VCAM-1 inhibitors
CZ20012980A3 (cs) 1999-02-18 2002-04-17 F. Hoffmann-La Roche Ag Thioamidové deriváty
PL349463A1 (en) 1999-02-18 2002-07-29 Hoffmann La Roche Phenylalaninol derivatives
WO2009145839A1 (en) * 2008-04-04 2009-12-03 Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Polyamine compounds that bind tar rna of hiv and methods of treating viral disorders
CN101914052B (zh) * 2010-08-02 2012-06-27 胡建荣 一种奥拉西坦化合物的制备方法
CN102351770B (zh) * 2011-08-12 2012-07-04 江西新先锋医药有限公司 一种奥拉西坦化合物及其药物组合物
CN112724062B (zh) * 2021-01-19 2022-03-15 江苏诚信药业有限公司 一种奥拉西坦杂质b的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH470396A (de) * 1963-08-12 1969-03-31 Hoffmann La Roche Verfahren zur Herstellung von 4-Imidazolidon-Verbindungen
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
YU39660B (en) * 1976-01-14 1985-03-20 Pliva Pharm & Chem Works Process for obtaining 2-oxo-1-pyrrolidine acetamide
AT360980B (de) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works Verfahren zur herstellung von n-alkylamiden des 2-oxo-1-pyrrolidins
GB1539817A (en) * 1976-10-22 1979-02-07 Ucb Sa N-substituted lactams
IT1075564B (it) * 1977-02-11 1985-04-22 Isf Spa Procedimento per la preparazione di derivati pirrolidinici
IT1141287B (it) * 1979-06-13 1986-10-01 Nattermann A & Cie Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
EP0115473A3 (de) * 1983-01-27 1987-01-21 Ciba-Geigy Ag Substituierte Pyrrolidinonderivate und Verfahren zu ihrer Herstellung
IT1209644B (it) * 1985-06-21 1989-08-30 Isf Spa Composti farmacologicamente attivi.
JPH0681502B2 (ja) * 1988-07-14 1994-10-12 富士通電装株式会社 並列運転保護回路

Also Published As

Publication number Publication date
EP0207681A3 (en) 1988-06-01
NZ216550A (en) 1990-02-26
ES556351A0 (es) 1988-01-01
US4824861A (en) 1989-04-25
NO862486L (no) 1986-12-22
PT82813A (en) 1986-07-01
KR870000294A (ko) 1987-02-17
GR861577B (en) 1986-10-21
ES8800164A1 (es) 1987-11-01
JPS62461A (ja) 1987-01-06
IL79136A0 (en) 1986-09-30
PT82815A (en) 1986-07-01
PT82813B (pt) 1988-04-21
AU5891986A (en) 1986-12-24
NO862486D0 (no) 1986-06-20
ATE73821T1 (de) 1992-04-15
AU587258B2 (en) 1989-08-10
EP0207681A2 (en) 1987-01-07
IT8521234A0 (it) 1985-06-21
ZA864444B (en) 1987-02-25
FI862420A0 (fi) 1986-06-06
DE3684368D1 (de) 1992-04-23
PH22851A (en) 1989-01-19
FI82446B (fi) 1990-11-30
NO168428B (no) 1991-11-11
HUT43815A (en) 1987-12-28
HU196225B (en) 1988-10-28
IT1190378B (it) 1988-02-16
CA1284248C (en) 1991-05-14
FI862420A (fi) 1986-12-22
PT82815B (pt) 1988-04-21
KR930006766B1 (ko) 1993-07-23
DK290286D0 (da) 1986-06-20
IL79136A (en) 1991-07-18
EP0207681B1 (en) 1992-03-18
ES556353A0 (es) 1987-11-01
NO168428C (no) 1992-02-19
ES8801201A1 (es) 1988-01-01
FI82446C (fi) 1991-03-11

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment