DK2814508T5 - Rotavirus-underenhedsvacciner og fremgangsmåder til fremstilling og anvendelse deraf - Google Patents

Rotavirus-underenhedsvacciner og fremgangsmåder til fremstilling og anvendelse deraf Download PDF

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Publication number
DK2814508T5
DK2814508T5 DK13706871.4T DK13706871T DK2814508T5 DK 2814508 T5 DK2814508 T5 DK 2814508T5 DK 13706871 T DK13706871 T DK 13706871T DK 2814508 T5 DK2814508 T5 DK 2814508T5
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Denmark
Prior art keywords
rotavirus
vaccines
procedures
substances
producing
Prior art date
Application number
DK13706871.4T
Other languages
English (en)
Other versions
DK2814508T3 (da
Inventor
Russell F Bey
Randy R Simonson
Benjamin Matthew Hause
Kamesh Reddy Sirigireddy
Original Assignee
Merial Inc
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Publication of DK2814508T3 publication Critical patent/DK2814508T3/da
Publication of DK2814508T5 publication Critical patent/DK2814508T5/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/15Reoviridae, e.g. calf diarrhea virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12311Rotavirus, e.g. rotavirus A
    • C12N2720/12334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK13706871.4T 2012-02-14 2013-02-14 Rotavirus-underenhedsvacciner og fremgangsmåder til fremstilling og anvendelse deraf DK2814508T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261598624P 2012-02-14 2012-02-14
PCT/US2013/026179 WO2013123219A1 (en) 2012-02-14 2013-02-14 Rotavirus subunit vaccines and methods of making and use thereof

Publications (2)

Publication Number Publication Date
DK2814508T3 DK2814508T3 (da) 2017-05-22
DK2814508T5 true DK2814508T5 (da) 2017-06-12

Family

ID=47755047

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13706871.4T DK2814508T5 (da) 2012-02-14 2013-02-14 Rotavirus-underenhedsvacciner og fremgangsmåder til fremstilling og anvendelse deraf

Country Status (22)

Country Link
US (1) US9446117B2 (da)
EP (1) EP2814508B1 (da)
JP (1) JP6149240B2 (da)
KR (1) KR102087458B1 (da)
CN (1) CN104203274B (da)
AR (2) AR089995A1 (da)
AU (1) AU2013221479B2 (da)
BR (1) BR112014020025B1 (da)
CA (1) CA2864106C (da)
DK (1) DK2814508T5 (da)
EA (1) EA034564B1 (da)
ES (1) ES2632429T3 (da)
HK (1) HK1200326A1 (da)
HU (1) HUE033858T2 (da)
LT (1) LT2814508T (da)
MX (1) MX353786B (da)
NZ (1) NZ628282A (da)
PH (1) PH12014501795B1 (da)
PL (1) PL2814508T3 (da)
PT (1) PT2814508T (da)
SI (1) SI2814508T1 (da)
WO (1) WO2013123219A1 (da)

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US10004797B2 (en) 2010-10-27 2018-06-26 Harrisvaccines, Inc. Method of rapidly producing improved vaccines for animals
RU2649132C1 (ru) * 2017-08-03 2018-03-29 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства Способ получения активного начала вакцины против ротавирусной инфекции белка FliCVP6VP8
CN108864260A (zh) * 2018-07-17 2018-11-23 昆明学院 非结构蛋白nsp4、重组杆状病毒液及制备、粘膜佐剂
CN109306007B (zh) * 2018-09-26 2021-10-08 华中农业大学 抗猪繁殖与呼吸综合征病毒nsp4蛋白基因工程抗体及应用
US20220160864A1 (en) * 2020-10-05 2022-05-26 Boehringer Ingelheim Animal Health USA Inc. Fusion protein comprising circoviridae capsid protein, and chimeric virus-like particles composed thereof
CN114875047A (zh) * 2022-05-27 2022-08-09 江苏三仪生物工程有限公司 一种优化的猪轮状病毒外衣壳蛋白vp4的重组表达及应用

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DE3584341D1 (de) 1984-08-24 1991-11-14 Upjohn Co Rekombinante dna-verbindungen und expression von polypeptiden wie tpa.
US5186933A (en) 1986-12-30 1993-02-16 Baylor College Of Medicine Synthesis and immunogenicity of rotavirus genes using a baculovirus expression system
US5147639A (en) * 1990-06-19 1992-09-15 Ambico, Inc. Type-c rotavirus cultures and uses therefor
US5298244A (en) 1990-10-25 1994-03-29 University Of Saskatchewan Assembled viral particles and their use in a vaccine to rotaviral disease
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JPH11504631A (ja) 1995-04-25 1999-04-27 バイカル インコーポレイテッド Dna/脂質複合体の単一バイアル製剤
ATE248601T1 (de) 1995-06-14 2003-09-15 Baylor College Medicine Impfstoff gegen rotavirus infektionen enthaltend peptide des viralenterotoxines nsp4
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FR2751226B1 (fr) 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies du cheval
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Also Published As

Publication number Publication date
EA034564B1 (ru) 2020-02-20
MX353786B (es) 2018-01-29
AR126891A2 (es) 2023-11-29
WO2013123219A1 (en) 2013-08-22
PT2814508T (pt) 2017-07-19
BR112014020025A8 (pt) 2022-07-12
SI2814508T1 (sl) 2017-10-30
MX2014009722A (es) 2015-02-20
PH12014501795A1 (en) 2014-11-17
BR112014020025A2 (pt) 2017-07-04
EP2814508B1 (en) 2017-04-12
JP2015508776A (ja) 2015-03-23
LT2814508T (lt) 2017-06-26
CA2864106A1 (en) 2013-08-22
JP6149240B2 (ja) 2017-06-21
AU2013221479B2 (en) 2017-06-08
US9446117B2 (en) 2016-09-20
PL2814508T3 (pl) 2017-09-29
DK2814508T3 (da) 2017-05-22
ES2632429T3 (es) 2017-09-13
NZ628282A (en) 2016-08-26
AU2013221479A1 (en) 2014-08-28
KR20140123592A (ko) 2014-10-22
EA201400914A1 (ru) 2014-12-30
CN104203274A (zh) 2014-12-10
US20130209507A1 (en) 2013-08-15
BR112014020025B1 (pt) 2022-09-27
HUE033858T2 (en) 2018-01-29
PH12014501795B1 (en) 2014-11-17
EP2814508A1 (en) 2014-12-24
CN104203274B (zh) 2017-09-08
HK1200326A1 (en) 2015-08-07
KR102087458B1 (ko) 2020-03-10
CA2864106C (en) 2017-10-17
AR089995A1 (es) 2014-10-01

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