PT2814508T - Vacinas de subunidades de rotavírus e métodos para as produzir e uso das mesmas - Google Patents

Vacinas de subunidades de rotavírus e métodos para as produzir e uso das mesmas

Info

Publication number
PT2814508T
PT2814508T PT137068714T PT13706871T PT2814508T PT 2814508 T PT2814508 T PT 2814508T PT 137068714 T PT137068714 T PT 137068714T PT 13706871 T PT13706871 T PT 13706871T PT 2814508 T PT2814508 T PT 2814508T
Authority
PT
Portugal
Prior art keywords
making
methods
subunit vaccines
rotavirus subunit
rotavirus
Prior art date
Application number
PT137068714T
Other languages
English (en)
Inventor
F Bey Russell
R Simonson Randy
Reddy Sirigireddy Kamesh
Matthew Hause Benjamin
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Inc filed Critical Merial Inc
Publication of PT2814508T publication Critical patent/PT2814508T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
PT137068714T 2012-02-14 2013-02-14 Vacinas de subunidades de rotavírus e métodos para as produzir e uso das mesmas PT2814508T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261598624P 2012-02-14 2012-02-14

Publications (1)

Publication Number Publication Date
PT2814508T true PT2814508T (pt) 2017-07-19

Family

ID=47755047

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137068714T PT2814508T (pt) 2012-02-14 2013-02-14 Vacinas de subunidades de rotavírus e métodos para as produzir e uso das mesmas

Country Status (22)

Country Link
US (1) US9446117B2 (pt)
EP (1) EP2814508B1 (pt)
JP (1) JP6149240B2 (pt)
KR (1) KR102087458B1 (pt)
CN (1) CN104203274B (pt)
AR (2) AR089995A1 (pt)
AU (1) AU2013221479B2 (pt)
BR (1) BR112014020025B1 (pt)
CA (1) CA2864106C (pt)
DK (1) DK2814508T5 (pt)
EA (1) EA034564B1 (pt)
ES (1) ES2632429T3 (pt)
HK (1) HK1200326A1 (pt)
HU (1) HUE033858T2 (pt)
LT (1) LT2814508T (pt)
MX (1) MX353786B (pt)
NZ (1) NZ628282A (pt)
PH (1) PH12014501795B1 (pt)
PL (1) PL2814508T3 (pt)
PT (1) PT2814508T (pt)
SI (1) SI2814508T1 (pt)
WO (1) WO2013123219A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10004797B2 (en) 2010-10-27 2018-06-26 Harrisvaccines, Inc. Method of rapidly producing improved vaccines for animals
RU2649132C1 (ru) * 2017-08-03 2018-03-29 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства Способ получения активного начала вакцины против ротавирусной инфекции белка FliCVP6VP8
CN108864260A (zh) * 2018-07-17 2018-11-23 昆明学院 非结构蛋白nsp4、重组杆状病毒液及制备、粘膜佐剂
CN109306007B (zh) * 2018-09-26 2021-10-08 华中农业大学 抗猪繁殖与呼吸综合征病毒nsp4蛋白基因工程抗体及应用
CN116438202A (zh) * 2020-10-05 2023-07-14 勃林格殷格翰动物保健美国有限公司 包含圆环病毒科衣壳蛋白的融合蛋白及其构成的嵌合病毒样颗粒
CN114875047A (zh) * 2022-05-27 2022-08-09 江苏三仪生物工程有限公司 一种优化的猪轮状病毒外衣壳蛋白vp4的重组表达及应用

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
US4708871A (en) 1983-03-08 1987-11-24 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
DE3584341D1 (de) 1984-08-24 1991-11-14 Upjohn Co Rekombinante dna-verbindungen und expression von polypeptiden wie tpa.
US5186933A (en) 1986-12-30 1993-02-16 Baylor College Of Medicine Synthesis and immunogenicity of rotavirus genes using a baculovirus expression system
US5147639A (en) * 1990-06-19 1992-09-15 Ambico, Inc. Type-c rotavirus cultures and uses therefor
US5298244A (en) 1990-10-25 1994-03-29 University Of Saskatchewan Assembled viral particles and their use in a vaccine to rotaviral disease
BE1006085A3 (fr) 1992-07-31 1994-05-10 Univ Bruxelles Vecteur de clonage.
EP0826063A1 (en) 1995-04-25 1998-03-04 Vical Incorporated Single-vial formulations of dna/lipid complexes
US6673355B1 (en) * 1995-06-14 2004-01-06 Baylor College Of Medicine Rotavirus enterotoxin NSP4 and methods of using same
US6210682B1 (en) 1995-06-14 2001-04-03 Baylor College Of Medicine Rotavirus enterotoxin NSP4 and methods of using same
US5846946A (en) 1996-06-14 1998-12-08 Pasteur Merieux Serums Et Vaccins Compositions and methods for administering Borrelia DNA
FR2751224B1 (fr) 1996-07-19 1998-11-20 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs
FR2751225B1 (fr) 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique aviaire
FR2751228B1 (fr) 1996-07-19 1998-11-20 Rhone Merieux Vaccin polynucleotidique bovin pour voie intradermique
FR2751226B1 (fr) 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies du cheval
FR2751229B1 (fr) 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins
FR2751227B1 (fr) 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies canines, notamment les pathologies respiratoires et digestives
WO1998016247A1 (en) 1996-10-11 1998-04-23 The Regents Of The University Of California Immunostimulatory polynucleotide/immunomodulatory molecule conjugates
EP0991426B2 (fr) 1997-06-30 2007-03-28 Institut Gustave Roussy Procede de transfert d'acide nucleique dans le muscle strie
WO1999058652A2 (en) 1998-05-07 1999-11-18 Gx Biosystems A/S Cytotoxin-based biological containment
FR2778858B1 (fr) 1998-05-20 2000-06-16 Oreal Emulsion e/h/e stable et son utilisation comme composition cosmetique et/ou dermatologique
US6716431B1 (en) 1998-05-29 2004-04-06 Wyeth Holdings Corporation Differential cytotoxicity of alternative forms of rotavirus nonstructural protein 4
US6187319B1 (en) 1998-06-01 2001-02-13 University Of Massachusetts Cross-protective rotavirus vaccine
US6589529B1 (en) 1998-10-30 2003-07-08 Children's Hospital Medical Center Rotavirus subunit vaccine
FR2801607B1 (fr) 1999-11-26 2001-12-28 Merial Sas Pneumovirus du canard et vaccins correspondants
US6852705B2 (en) 2000-01-21 2005-02-08 Merial DNA vaccines for farm animals, in particular bovines and porcines
US6867353B2 (en) 2000-02-12 2005-03-15 Exploregen Inc. Production method of recombinant rotavirus structural proteins and vaccine composition
AU2002220025A1 (en) * 2000-11-03 2002-05-15 Baylor College Of Medicine Rotavirus enterotoxin NSP4 and methods of using same
US7790178B2 (en) 2002-12-19 2010-09-07 Intervet International B.V. Trivalent vaccine with maternal anitbody transfer via the milk
UA84024C2 (ru) * 2003-07-24 2008-09-10 Мериал Лимитед Новые вакцинные композиции, которые содержат эмульсию типа "масло в воде"
WO2006007555A2 (en) * 2004-07-01 2006-01-19 Children's Medical Center Corporation ¨ Rotavirus antigens
US7691368B2 (en) * 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
BRPI0504441A (pt) * 2005-10-20 2007-06-26 Fundacao Oswaldo Cruz vetores de expressão plasmidial contendo regiões especìficas para a expressão de proteìnas ou epìtopos recombinantes de rotavìrus e astrovìrus, processo de produção dos insumos para geração de imunobiológicos para diagnóstico
CN101448521A (zh) * 2006-03-03 2009-06-03 梅瑞尔有限公司 猪肺炎支原体疫苗
AU2009256397B2 (en) 2008-05-29 2014-06-05 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Expression and assembly of human group C rotavirus-like particles and uses thereof
CA2730741C (en) 2008-07-18 2016-10-25 Regis Sodoyer Self-replicating vector lacking an antibiotic-resistance gene
ES2600929T3 (es) 2009-09-10 2017-02-13 Merial, Inc. Nuevas formulaciones de vacuna que comprenden adyuvantes que contienen saponina

Also Published As

Publication number Publication date
PH12014501795A1 (en) 2014-11-17
EA034564B1 (ru) 2020-02-20
EP2814508B1 (en) 2017-04-12
LT2814508T (lt) 2017-06-26
BR112014020025A2 (pt) 2017-07-04
CA2864106A1 (en) 2013-08-22
JP2015508776A (ja) 2015-03-23
CN104203274A (zh) 2014-12-10
AU2013221479A1 (en) 2014-08-28
US20130209507A1 (en) 2013-08-15
MX353786B (es) 2018-01-29
JP6149240B2 (ja) 2017-06-21
US9446117B2 (en) 2016-09-20
AU2013221479B2 (en) 2017-06-08
WO2013123219A1 (en) 2013-08-22
PL2814508T3 (pl) 2017-09-29
CN104203274B (zh) 2017-09-08
EP2814508A1 (en) 2014-12-24
SI2814508T1 (sl) 2017-10-30
HK1200326A1 (en) 2015-08-07
ES2632429T3 (es) 2017-09-13
PH12014501795B1 (en) 2014-11-17
EA201400914A1 (ru) 2014-12-30
CA2864106C (en) 2017-10-17
DK2814508T3 (da) 2017-05-22
DK2814508T5 (da) 2017-06-12
MX2014009722A (es) 2015-02-20
AR126891A2 (es) 2023-11-29
AR089995A1 (es) 2014-10-01
KR20140123592A (ko) 2014-10-22
BR112014020025A8 (pt) 2022-07-12
NZ628282A (en) 2016-08-26
HUE033858T2 (en) 2018-01-29
BR112014020025B1 (pt) 2022-09-27
KR102087458B1 (ko) 2020-03-10

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