DK2805954T3 - 7-substitueret hanfangichin b-derivat, og fremstillingsfremgangsmåde og anvendelse deraf - Google Patents

7-substitueret hanfangichin b-derivat, og fremstillingsfremgangsmåde og anvendelse deraf Download PDF

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Publication number
DK2805954T3
DK2805954T3 DK13738800.5T DK13738800T DK2805954T3 DK 2805954 T3 DK2805954 T3 DK 2805954T3 DK 13738800 T DK13738800 T DK 13738800T DK 2805954 T3 DK2805954 T3 DK 2805954T3
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DK
Denmark
Prior art keywords
hanfangichin
derivate
substituted
preparation
application
Prior art date
Application number
DK13738800.5T
Other languages
Danish (da)
English (en)
Inventor
Frank Rong
Rongzhen Xu
Hongxi Lai
Fuwen Xie
Original Assignee
Hangzhou Bensheng Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hangzhou Bensheng Pharmaceutical Co Ltd filed Critical Hangzhou Bensheng Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DK2805954T3 publication Critical patent/DK2805954T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK13738800.5T 2012-01-21 2013-01-21 7-substitueret hanfangichin b-derivat, og fremstillingsfremgangsmåde og anvendelse deraf DK2805954T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2012070698 2012-01-21
PCT/CN2013/070800 WO2013107428A1 (zh) 2012-01-21 2013-01-21 7-位取代的汉防己乙素衍生物、及其制备方法和应用

Publications (1)

Publication Number Publication Date
DK2805954T3 true DK2805954T3 (da) 2019-09-23

Family

ID=48798682

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13738800.5T DK2805954T3 (da) 2012-01-21 2013-01-21 7-substitueret hanfangichin b-derivat, og fremstillingsfremgangsmåde og anvendelse deraf

Country Status (5)

Country Link
US (1) US9328122B2 (enExample)
EP (1) EP2805954B1 (enExample)
JP (1) JP6298768B2 (enExample)
DK (1) DK2805954T3 (enExample)
WO (1) WO2013107428A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107207524B (zh) * 2014-08-15 2020-02-07 贵州省中国科学院天然产物化学重点实验室 双苄基异喹啉衍生物、其制备方法及其在肝病的治疗与预防中的用途
CN107033157B (zh) * 2016-02-03 2020-05-05 贵州省中国科学院天然产物化学重点实验室 双苄基异喹啉衍生物及其在制备用于治疗或预防肿瘤的药物中的用途
CN109776553B (zh) * 2019-01-15 2020-05-29 山东师范大学 福己素及其制备方法和应用
CN110156808B (zh) * 2019-06-21 2022-01-18 华中农业大学 具有杀菌活性的防己诺林碱-氨基甲酸酯类衍生物
CN112250690B (zh) * 2020-09-24 2022-07-15 山东师范大学 磺酰基防己诺林碱类化合物及其制备方法和应用
CN114031623B (zh) * 2021-11-12 2023-04-11 山西医科大学 一种c14位氨基取代粉防己碱衍生物及其制备和应用
CN116731031A (zh) * 2023-06-16 2023-09-12 贵州药法自然医药科技有限公司 芬氏唐松草碱衍生物及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0678232B2 (ja) * 1986-03-07 1994-10-05 株式会社ツムラ アンジオテンシンｉ転換酵素阻害剤
JPH02134382A (ja) * 1988-11-14 1990-05-23 Kaken Shiyouyaku Kk ビスベンジルイソキノリン誘導体
JPH02243627A (ja) * 1989-03-16 1990-09-27 Tsumura & Co 狭心症治療薬
CN1111160C (zh) 2000-09-08 2003-06-11 成都康弘制药有限公司 双苄基异喹啉类生物碱和药物组合物及用途
CN1511528A (zh) 2002-12-30 2004-07-14 北京大学第一医院 防己诺林碱在抑制血管生成药物中的应用
CN1511527A (zh) * 2002-12-31 2004-07-14 北京大学第一医院 粉防已碱在抑制血管生成药物中的应用
CN101371839B (zh) 2008-10-08 2010-11-03 中国科学院化学研究所 双苄基异喹啉类生物碱的新用途

Also Published As

Publication number Publication date
JP2015504075A (ja) 2015-02-05
US20140357647A1 (en) 2014-12-04
EP2805954A1 (en) 2014-11-26
WO2013107428A1 (zh) 2013-07-25
EP2805954B1 (en) 2019-06-19
EP2805954A4 (en) 2015-10-21
JP6298768B2 (ja) 2018-03-20
US9328122B2 (en) 2016-05-03

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DK2805954T3 (da) 7-substitueret hanfangichin b-derivat, og fremstillingsfremgangsmåde og anvendelse deraf