DK2611832T3 - ANTI-CXCL13 ANTIBODIES AND PROCEDURES FOR USE THEREOF - Google Patents
ANTI-CXCL13 ANTIBODIES AND PROCEDURES FOR USE THEREOF Download PDFInfo
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- DK2611832T3 DK2611832T3 DK11822655.4T DK11822655T DK2611832T3 DK 2611832 T3 DK2611832 T3 DK 2611832T3 DK 11822655 T DK11822655 T DK 11822655T DK 2611832 T3 DK2611832 T3 DK 2611832T3
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- Health & Medical Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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Applications Claiming Priority (3)
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| US201161481645P | 2011-05-02 | 2011-05-02 | |
| PCT/US2011/050177 WO2012031099A2 (en) | 2010-09-02 | 2011-09-01 | Anti-cxcl13 antibodies and methods of using the same |
Publications (1)
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Family
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| WO (1) | WO2012031099A2 (OSRAM) |
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| MX2011011718A (es) | 2009-05-08 | 2012-01-27 | Vaccinex Inc | Anticuerpos anti-cd100 y metodos para su uso. |
| SG188285A1 (en) | 2010-09-02 | 2013-04-30 | Vaccinex Inc | Anti-cxcl13 antibodies and methods of using the same |
| WO2012082494A2 (en) | 2010-12-14 | 2012-06-21 | Morehouse School Of Medicine | The use of anti-cxcl13 and anti-cxcr5 antibodies for the treatment or detection of cancer |
| DK2766093T3 (en) | 2011-10-11 | 2018-06-06 | Vaccinex Inc | USE OF SEMAPHORIN-4D BINDING MOLECULES FOR MODULATING THE PERMEABILITY OF THE BLOOD-BRAIN BARRIER |
| KR102090969B1 (ko) * | 2012-03-02 | 2020-03-19 | 백시넥스 인코포레이티드 | Ｂ 세포-매개 염증 질환의 치료 방법 |
| US9708601B2 (en) | 2012-04-26 | 2017-07-18 | Vaccinex, Inc. | Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus |
| WO2014003742A1 (en) * | 2012-06-27 | 2014-01-03 | Morehouse School Of Medicine | Anti-cxcl9, anti-cxcl10, anti-cxcl11, anti-cxcl13, anti-cxcr3 and anti-cxcr5 agents for inhibition of inflammation |
| CN104884955B (zh) * | 2012-12-07 | 2017-06-27 | 巴克斯特国际公司 | 抗‑mif抗体的细胞迁移测定方法 |
| JP6363623B2 (ja) * | 2013-01-31 | 2018-07-25 | ヴァクシネックス， インコーポレイテッド | 免疫グロブリンａのレベルを増大するための方法 |
| BR112015021964A2 (pt) * | 2013-03-08 | 2017-08-29 | Vaccinex Inc | Anticorpo isolado ou um fragmento ligante de antígenos do mesmo que se liga especificamente a cxcl13, composição e seus usos |
| DK3013350T3 (da) | 2013-06-25 | 2020-04-14 | Vaccinex Inc | Anvendelse af semaphorin-4D-hæmmende molekyler i kombination med en immunmodulerende terapi for at hæmme tumorvækst og metastaser |
| AU2016323153B2 (en) | 2015-09-15 | 2021-04-22 | Board Of Regents, The University Of Texas System | T-cell receptor (TCR)-binding antibodies and uses thereof |
| SG11201808554TA (en) | 2016-04-22 | 2018-11-29 | Vaccinex Inc | Integral membrane protein display on poxvirus extracellular enveloped virions |
| SG11201900595YA (en) | 2016-08-02 | 2019-02-27 | Vaccinex Inc | Improved methods for producing polynucleotide libraries in vaccinia virus/eukaryotic cells |
| CN111615520A (zh) | 2017-12-01 | 2020-09-01 | 辉瑞大药厂 | 抗cxcr5抗体及其组合物和用途 |
| JP7654548B2 (ja) * | 2018-09-17 | 2025-04-01 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 抗ｋｌｒｇ１抗体 |
| KR20200106056A (ko) * | 2018-09-18 | 2020-09-10 | 아이-맵 바이오파마 유에스 리미티드 | 자가면역 질환 및 암을 치료하기 위한 항-cxcl13 항체 |
| JP7748728B2 (ja) * | 2020-06-11 | 2025-10-03 | インペリアル・カレッジ・イノベーションズ・リミテッド | 末梢神経再生を促進するためのｃｘｃｌ１３結合分子の使用 |
| CN115975946A (zh) * | 2022-12-01 | 2023-04-18 | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 表达趋化因子cxcl10、cxcl13、ccl19的免疫细胞及其制备方法与应用 |
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| BR112015021964A2 (pt) | 2013-03-08 | 2017-08-29 | Vaccinex Inc | Anticorpo isolado ou um fragmento ligante de antígenos do mesmo que se liga especificamente a cxcl13, composição e seus usos |
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| US20150050287A9 (en) | 2015-02-19 |
| EP2611832A2 (en) | 2013-07-10 |
| WO2012031099A3 (en) | 2012-06-07 |
| JP2013539369A (ja) | 2013-10-24 |
| SG188285A1 (en) | 2013-04-30 |
| KR101862236B1 (ko) | 2018-05-29 |
| JP6097690B2 (ja) | 2017-03-15 |
| US10829550B2 (en) | 2020-11-10 |
| CA2810217C (en) | 2019-03-12 |
| CN103347896B (zh) | 2017-06-13 |
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| US20210087263A1 (en) | 2021-03-25 |
| WO2012031099A9 (en) | 2012-08-30 |
| US9963504B2 (en) | 2018-05-08 |
| AU2011295902A1 (en) | 2013-04-11 |
| MX2013002495A (es) | 2013-06-05 |
| MX353476B (es) | 2018-01-15 |
| KR20130101046A (ko) | 2013-09-12 |
| CA2810217A1 (en) | 2012-03-08 |
| US20180244764A1 (en) | 2018-08-30 |
| NZ608318A (en) | 2015-03-27 |
| BR112013005145B1 (pt) | 2022-02-15 |
| US11981730B2 (en) | 2024-05-14 |
| WO2012031099A2 (en) | 2012-03-08 |
| EP2611832A4 (en) | 2014-03-05 |
| US20140147447A1 (en) | 2014-05-29 |
| AU2011295902B2 (en) | 2014-12-04 |
| BR112013005145A2 (pt) | 2016-05-10 |
| JP2017099379A (ja) | 2017-06-08 |
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