DK2567240T4 - Lipidomiske biomarkører til aterosklerose og kardiovaskulær sygdom - Google Patents

Lipidomiske biomarkører til aterosklerose og kardiovaskulær sygdom Download PDF

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Publication number
DK2567240T4
DK2567240T4 DK11719802.8T DK11719802T DK2567240T4 DK 2567240 T4 DK2567240 T4 DK 2567240T4 DK 11719802 T DK11719802 T DK 11719802T DK 2567240 T4 DK2567240 T4 DK 2567240T4
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biomarkears
aterosclerosis
lipidomic
cardiovascular disease
cardiovascular
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DK11719802.8T
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DK2567240T3 (da
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Reijo Laaksonen
Kim Ekroos
Reini Hurme
Minna Jänis
Riikka Katainen
Kirill Tarasov
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Zora Biosciences Oy
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/323—Arteriosclerosis, Stenosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK11719802.8T 2010-05-05 2011-05-05 Lipidomiske biomarkører til aterosklerose og kardiovaskulær sygdom DK2567240T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33146310P 2010-05-05 2010-05-05
EP10162066.4A EP2385374B2 (en) 2010-05-05 2010-05-05 Lipidomic biomarkers for atherosclerosis and cardiovascular disease
PCT/EP2011/057254 WO2011138419A1 (en) 2010-05-05 2011-05-05 Lipidomic biomarkers for atherosclerosis and cardiovascular disease

Publications (2)

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DK2567240T3 DK2567240T3 (da) 2018-06-14
DK2567240T4 true DK2567240T4 (da) 2021-05-31

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DK10162066.4T DK2385374T4 (da) 2010-05-05 2010-05-05 Lipidomik-biomarkører for atherosklerose og kardiovaskulær sygdom
DK11719802.8T DK2567240T4 (da) 2010-05-05 2011-05-05 Lipidomiske biomarkører til aterosklerose og kardiovaskulær sygdom

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US (5) US9046538B2 (da)
EP (3) EP2385374B2 (da)
JP (1) JP5871244B2 (da)
CN (1) CN102971633B (da)
CA (1) CA2798238C (da)
DK (2) DK2385374T4 (da)
ES (2) ES2455124T5 (da)
NO (2) NO2385374T3 (da)
WO (1) WO2011138419A1 (da)

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WO2011138419A1 (en) 2011-11-10
US9046538B2 (en) 2015-06-02
US20180321266A1 (en) 2018-11-08
US9857386B2 (en) 2018-01-02
CA2798238A1 (en) 2011-11-10
EP2385374B1 (en) 2014-01-08
EP2567240A1 (en) 2013-03-13
NO2567240T3 (da) 2018-09-01
CN102971633A (zh) 2013-03-13
US10551394B2 (en) 2020-02-04
CN102971633B (zh) 2016-08-10
DK2385374T3 (da) 2014-03-17
US20130045217A1 (en) 2013-02-21
US20150247873A1 (en) 2015-09-03
EP2385374B2 (en) 2018-02-28
ES2672054T5 (es) 2021-11-22
US20160363601A1 (en) 2016-12-15
EP3399318A1 (en) 2018-11-07
ES2672054T3 (es) 2018-06-12
JP2013527449A (ja) 2013-06-27
DK2385374T4 (da) 2018-04-30
EP2385374A1 (en) 2011-11-09
DK2567240T3 (da) 2018-06-14
EP3399318B1 (en) 2020-03-04
JP5871244B2 (ja) 2016-03-01
ES2455124T5 (es) 2018-05-08
EP2567240B2 (en) 2021-03-03
ES2455124T3 (es) 2014-04-14
CA2798238C (en) 2018-01-23
NO2385374T3 (da) 2014-06-07
US9459264B2 (en) 2016-10-04
US20210003598A1 (en) 2021-01-07
EP2567240B1 (en) 2018-04-04

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