DK255581A - Fremgangsmaade til fremstilling af et marcolidantibiotikum ellel en acylester eller et syreadditionssalt eller ester deraf - Google Patents

Fremgangsmaade til fremstilling af et marcolidantibiotikum ellel en acylester eller et syreadditionssalt eller ester deraf

Info

Publication number
DK255581A
DK255581A DK255581A DK255581A DK255581A DK 255581 A DK255581 A DK 255581A DK 255581 A DK255581 A DK 255581A DK 255581 A DK255581 A DK 255581A DK 255581 A DK255581 A DK 255581A
Authority
DK
Denmark
Prior art keywords
nrrl
strep
fradiae
new
deriv
Prior art date
Application number
DK255581A
Other languages
Danish (da)
English (en)
Inventor
R H Baltz
G M Wild
E T Seno
H A Kirst
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/156,855 external-priority patent/US4321362A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK255581A publication Critical patent/DK255581A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/54—Streptomyces fradiae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Processing Of Solid Wastes (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK255581A 1980-06-12 1981-06-11 Fremgangsmaade til fremstilling af et marcolidantibiotikum ellel en acylester eller et syreadditionssalt eller ester deraf DK255581A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/156,855 US4321362A (en) 1980-06-12 1980-06-12 De(mycinosyloxy)tylosin and process for its production

Publications (1)

Publication Number Publication Date
DK255581A true DK255581A (da) 1981-12-13

Family

ID=22561375

Family Applications (1)

Application Number Title Priority Date Filing Date
DK255581A DK255581A (da) 1980-06-12 1981-06-11 Fremgangsmaade til fremstilling af et marcolidantibiotikum ellel en acylester eller et syreadditionssalt eller ester deraf

Country Status (24)

Country Link
EP (1) EP0042694B1 (ja)
JP (1) JPS5731698A (ja)
KR (1) KR840001957B1 (ja)
AT (1) ATE6468T1 (ja)
AU (1) AU544358B2 (ja)
CA (1) CA1172190A (ja)
CS (1) CS225842B2 (ja)
DD (1) DD159645A5 (ja)
DE (1) DE3162501D1 (ja)
DK (1) DK255581A (ja)
ES (1) ES502981A0 (ja)
FI (1) FI811827L (ja)
GB (1) GB2077730B (ja)
GR (1) GR75276B (ja)
HU (1) HU189979B (ja)
IE (1) IE51613B1 (ja)
IL (1) IL63076A (ja)
NZ (1) NZ197360A (ja)
PH (1) PH15924A (ja)
PT (1) PT73164B (ja)
RO (1) RO81017A (ja)
SU (1) SU1134120A3 (ja)
YU (1) YU144281A (ja)
ZA (1) ZA813578B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423148A (en) * 1982-07-02 1983-12-27 Eli Lilly And Company Process for producing 20-dihydro-20-deoxy-23-de(mycinosyloxy)tylosin
US4435388A (en) 1982-06-10 1984-03-06 Schering Corporation Tylosin 20-imino-20-deoxo-4"-acyl derivatives, pharmaceutical compositions and method of use
JPS58219197A (ja) * 1982-06-15 1983-12-20 Sanraku Inc マクロライド系抗生物質の誘導体
US4436729A (en) * 1982-06-30 1984-03-13 Schering Corporation 23-Demycinosyltylosin compounds, pharmaceutical compositions and method of use
US4452784A (en) * 1982-07-19 1984-06-05 Eli Lilly And Company C-23-Modified derivatives of DMT
IL71032A0 (en) * 1983-02-28 1984-05-31 Lilly Co Eli C-20 and c-23-modified macrolide derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1428452A (fr) * 1958-10-29 1966-02-18 Lilly Co Eli Méthodes de production de nouveaux composés organiques azotés, tels que la tylosine et la desmycosine
US4161523A (en) * 1972-11-15 1979-07-17 Schering Corporation Rosamicin esters, acid addition salts and methods for production thereof

Also Published As

Publication number Publication date
DE3162501D1 (en) 1984-04-12
AU544358B2 (en) 1985-05-23
PT73164B (en) 1982-07-16
CA1172190A (en) 1984-08-07
IL63076A0 (en) 1981-09-13
PH15924A (en) 1983-04-26
GR75276B (ja) 1984-07-13
ES8203963A1 (es) 1982-04-16
SU1134120A3 (ru) 1985-01-07
DD159645A5 (de) 1983-03-23
PT73164A (en) 1981-07-01
ZA813578B (en) 1983-01-26
GB2077730B (en) 1984-06-20
JPS5731698A (en) 1982-02-20
AU7144781A (en) 1981-12-17
CS225842B2 (en) 1984-02-13
ATE6468T1 (de) 1984-03-15
NZ197360A (en) 1984-03-30
KR840001957B1 (ko) 1984-10-26
FI811827L (fi) 1981-12-13
EP0042694B1 (en) 1984-03-07
IL63076A (en) 1984-07-31
GB2077730A (en) 1981-12-23
IE811296L (en) 1981-12-12
YU144281A (en) 1983-09-30
EP0042694A1 (en) 1981-12-30
ES502981A0 (es) 1982-04-16
RO81017A (ro) 1983-02-01
KR830006430A (ko) 1983-09-24
HU189979B (en) 1986-08-28
IE51613B1 (en) 1987-01-21

Similar Documents

Publication Publication Date Title
JPS55162791A (en) Antibiotic c-15003pnd and its preparation
DK255581A (da) Fremgangsmaade til fremstilling af et marcolidantibiotikum ellel en acylester eller et syreadditionssalt eller ester deraf
DE3066026D1 (en) A method for the production of antibiotic c-15003 p-3
KR870004144A (ko) 항종양 항생제(ll-e33288 복합체)의 제법
JPS561894A (en) Preparation of antibiotic 3"-n-demethyl-sisomicin
DK158083A (da) Fremgangsmaade til fremstilling af et antibiotisk komplex, omfattende erythromycin d og estere deraf, eller dets enkelte komponenter
JPS57170189A (en) Dc-52 and its preparation
ATE18233T1 (de) De-(mycinosyloxy)-tylosin-derivate.
DE3884741D1 (de) Mikrobiologisches Verfahren zur Herstellung von UK-61.689 und Mikroorganismen zur Verwendung darin.
DE3169901D1 (en) Antibiotic am-5344-a2 and process for the preparation thereof
KR910014509A (ko) 항생성 알리사마이신, 이의 제조방법 및 용도
KR840007884A (ko) 마크로라이드 항생물질의 제조방법
KR850006873A (ko) 산성 폴리사이클릭 에테르 항생물질의 제조방법
JPS57105194A (en) Novel antibiotic xk-210 and its preparation
JPS642590A (en) Production of sulfide oxide having oxygen functional group at beta-position
FR2201074A1 (en) Antibiotic violamycin - with antitumour, virucidal and antimycoplasma activity
JPS56154998A (en) Production of macrolide antibiotic through microbial conversion process
IT1212860B (it) Sostanze ss 12538 fisiologicamente attive, loro preparazione e microorganismo che le produce
JPS5568294A (en) Production of trehalase inhibitor s-gi using microorganism
FR2277593A1 (fr) Procede de production de l'antibiotique dit tm-743 et nouveau produit ainsi obtenu
ES8703882A1 (es) Procedimiento para la obtencion del acido clavulanico y sus sales alcalinas
JPS5498793A (en) Deacylated antibiotic and its preparation
ES457579A1 (es) Un procedimiento para la produccion de los antibioticos antitumorales ma 144-m1 y/o ma 144-m2
KR850007084A (ko) 항생물질의 제조방법
JPS57170190A (en) Novel antibiotic d-606 a and its preparation

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment