JPS5731698A - Macrolide antibiotic - Google Patents

Macrolide antibiotic

Info

Publication number
JPS5731698A
JPS5731698A JP9072481A JP9072481A JPS5731698A JP S5731698 A JPS5731698 A JP S5731698A JP 9072481 A JP9072481 A JP 9072481A JP 9072481 A JP9072481 A JP 9072481A JP S5731698 A JPS5731698 A JP S5731698A
Authority
JP
Japan
Prior art keywords
nrrl
strep
fradiae
new
deriv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9072481A
Other languages
English (en)
Inventor
Henrii Barutsu Richiyaado
Miyurieru Wairudo Jiin
Toomasu Seno Yuujiin
Andoriyuu Kaasuto Haabaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/156,855 external-priority patent/US4321362A/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JPS5731698A publication Critical patent/JPS5731698A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/54—Streptomyces fradiae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Processing Of Solid Wastes (AREA)
  • Compounds Of Unknown Constitution (AREA)
JP9072481A 1980-06-12 1981-06-11 Macrolide antibiotic Pending JPS5731698A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/156,855 US4321362A (en) 1980-06-12 1980-06-12 De(mycinosyloxy)tylosin and process for its production

Publications (1)

Publication Number Publication Date
JPS5731698A true JPS5731698A (en) 1982-02-20

Family

ID=22561375

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9072481A Pending JPS5731698A (en) 1980-06-12 1981-06-11 Macrolide antibiotic

Country Status (24)

Country Link
EP (1) EP0042694B1 (ja)
JP (1) JPS5731698A (ja)
KR (1) KR840001957B1 (ja)
AT (1) ATE6468T1 (ja)
AU (1) AU544358B2 (ja)
CA (1) CA1172190A (ja)
CS (1) CS225842B2 (ja)
DD (1) DD159645A5 (ja)
DE (1) DE3162501D1 (ja)
DK (1) DK255581A (ja)
ES (1) ES502981A0 (ja)
FI (1) FI811827L (ja)
GB (1) GB2077730B (ja)
GR (1) GR75276B (ja)
HU (1) HU189979B (ja)
IE (1) IE51613B1 (ja)
IL (1) IL63076A (ja)
NZ (1) NZ197360A (ja)
PH (1) PH15924A (ja)
PT (1) PT73164B (ja)
RO (1) RO81017A (ja)
SU (1) SU1134120A3 (ja)
YU (1) YU144281A (ja)
ZA (1) ZA813578B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423148A (en) * 1982-07-02 1983-12-27 Eli Lilly And Company Process for producing 20-dihydro-20-deoxy-23-de(mycinosyloxy)tylosin
US4435388A (en) 1982-06-10 1984-03-06 Schering Corporation Tylosin 20-imino-20-deoxo-4"-acyl derivatives, pharmaceutical compositions and method of use
JPS58219197A (ja) * 1982-06-15 1983-12-20 Sanraku Inc マクロライド系抗生物質の誘導体
US4436729A (en) * 1982-06-30 1984-03-13 Schering Corporation 23-Demycinosyltylosin compounds, pharmaceutical compositions and method of use
US4452784A (en) * 1982-07-19 1984-06-05 Eli Lilly And Company C-23-Modified derivatives of DMT
IL71032A0 (en) * 1983-02-28 1984-05-31 Lilly Co Eli C-20 and c-23-modified macrolide derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1428452A (fr) * 1958-10-29 1966-02-18 Lilly Co Eli Méthodes de production de nouveaux composés organiques azotés, tels que la tylosine et la desmycosine
US4161523A (en) * 1972-11-15 1979-07-17 Schering Corporation Rosamicin esters, acid addition salts and methods for production thereof

Also Published As

Publication number Publication date
DE3162501D1 (en) 1984-04-12
DK255581A (da) 1981-12-13
AU544358B2 (en) 1985-05-23
PT73164B (en) 1982-07-16
CA1172190A (en) 1984-08-07
IL63076A0 (en) 1981-09-13
PH15924A (en) 1983-04-26
GR75276B (ja) 1984-07-13
ES8203963A1 (es) 1982-04-16
SU1134120A3 (ru) 1985-01-07
DD159645A5 (de) 1983-03-23
PT73164A (en) 1981-07-01
ZA813578B (en) 1983-01-26
GB2077730B (en) 1984-06-20
AU7144781A (en) 1981-12-17
CS225842B2 (en) 1984-02-13
ATE6468T1 (de) 1984-03-15
NZ197360A (en) 1984-03-30
KR840001957B1 (ko) 1984-10-26
FI811827L (fi) 1981-12-13
EP0042694B1 (en) 1984-03-07
IL63076A (en) 1984-07-31
GB2077730A (en) 1981-12-23
IE811296L (en) 1981-12-12
YU144281A (en) 1983-09-30
EP0042694A1 (en) 1981-12-30
ES502981A0 (es) 1982-04-16
RO81017A (ro) 1983-02-01
KR830006430A (ko) 1983-09-24
HU189979B (en) 1986-08-28
IE51613B1 (en) 1987-01-21

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