DK2550366T3 - Methods for identifying inhibitors of the type III secretion system - Google Patents

Methods for identifying inhibitors of the type III secretion system Download PDF

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Publication number
DK2550366T3
DK2550366T3 DK11710752.4T DK11710752T DK2550366T3 DK 2550366 T3 DK2550366 T3 DK 2550366T3 DK 11710752 T DK11710752 T DK 11710752T DK 2550366 T3 DK2550366 T3 DK 2550366T3
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DK
Denmark
Prior art keywords
component
effector
t3ss
antibody
secretion
Prior art date
Application number
DK11710752.4T
Other languages
Danish (da)
English (en)
Inventor
Thomas C Marlovits
Julia Radics
Wolfgang Schmied
Original Assignee
Imba Inst Für Molekulare Biotechnologie Gmbh
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Application filed by Imba Inst Für Molekulare Biotechnologie Gmbh filed Critical Imba Inst Für Molekulare Biotechnologie Gmbh
Application granted granted Critical
Publication of DK2550366T3 publication Critical patent/DK2550366T3/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18Testing for antimicrobial activity of a material

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK11710752.4T 2010-03-23 2011-03-22 Methods for identifying inhibitors of the type III secretion system DK2550366T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10157397 2010-03-23
PCT/EP2011/054379 WO2011117259A1 (en) 2010-03-23 2011-03-22 Methods for identifying inhibitors of the type iii secretion system

Publications (1)

Publication Number Publication Date
DK2550366T3 true DK2550366T3 (en) 2014-12-15

Family

ID=42199515

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11710752.4T DK2550366T3 (en) 2010-03-23 2011-03-22 Methods for identifying inhibitors of the type III secretion system

Country Status (7)

Country Link
US (1) US20130130283A1 (enExample)
EP (1) EP2550366B1 (enExample)
JP (1) JP5714692B2 (enExample)
CA (1) CA2793586A1 (enExample)
DK (1) DK2550366T3 (enExample)
ES (1) ES2526316T3 (enExample)
WO (1) WO2011117259A1 (enExample)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5581476A (en) 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
CA2252372C (en) * 1996-04-23 2010-06-29 B. Brett Finlay Pathogenic escherichia coli associated protein
AU3243199A (en) 1998-03-05 1999-09-20 University Of British Columbia, The Methods for assaying type iii secretion inhibitors
US6248546B1 (en) * 1998-03-09 2001-06-19 Diagnostic Systems Laboratories, Inc. Assay of IGFBP complex
GB0112687D0 (en) * 2001-05-24 2001-07-18 Microbiological Res Authority Pharmaceutical use of secreted bacterial effector proteins
GB0304993D0 (en) * 2003-03-05 2003-04-09 Univ Nottingham Trent Novel screening method
WO2005113791A2 (en) 2004-05-07 2005-12-01 Johnson & Johnson Product Research And Development Methods of identifying modulators of bacterial type iii protein secretion system
EP1795609A1 (en) * 2005-12-06 2007-06-13 Sanofi-Aventis Deutschland GmbH Method for the diagnosis and treatment of cardiovascular diseases
CA2563214A1 (en) * 2006-10-12 2008-04-12 Institut Pasteur Shigella ipad protein and its use as a potential vaccine against shigella infection
WO2009145829A1 (en) 2008-04-01 2009-12-03 University Of Massachusetts Type iii secretion inhibitors, analogs and uses thereof
WO2009061491A2 (en) * 2007-11-07 2009-05-14 University Of Massachusetts Type iii secretion inhibitors and uses thereof
WO2009137133A2 (en) * 2008-02-14 2009-11-12 University Of Washington 5-substituted-2-imino-thiazolidinone compounds and their use as inhibitors of bacterial infection

Also Published As

Publication number Publication date
WO2011117259A1 (en) 2011-09-29
WO2011117259A9 (en) 2011-11-24
EP2550366A1 (en) 2013-01-30
JP5714692B2 (ja) 2015-05-07
JP2013522638A (ja) 2013-06-13
ES2526316T3 (es) 2015-01-09
EP2550366B1 (en) 2014-11-12
CA2793586A1 (en) 2011-09-29
US20130130283A1 (en) 2013-05-23

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