DK2488170T3 - Sammensætninger, der omfatter tramadol og celecoxib, til behandling af smerter - Google Patents
Sammensætninger, der omfatter tramadol og celecoxib, til behandling af smerter Download PDFInfo
- Publication number
- DK2488170T3 DK2488170T3 DK10765762.9T DK10765762T DK2488170T3 DK 2488170 T3 DK2488170 T3 DK 2488170T3 DK 10765762 T DK10765762 T DK 10765762T DK 2488170 T3 DK2488170 T3 DK 2488170T3
- Authority
- DK
- Denmark
- Prior art keywords
- pain
- celecoxib
- tramadol
- pharmaceutical composition
- rac
- Prior art date
Links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Claims (4)
1. Farmaceutisk sammensætning, omfattende en kombination af (rac)-tramadol-HCI og celecoxib eller et farmaceutisk acceptabelt salt eller hydrat deraf, hvor det molekylære forhold mellem (rac)-tramadol-HCI og celecoxib er et molforhold fra 1:1 til 1:5 eller fra 1:1 til 5:1.
2. Farmaceutisk sammensætning ifølge krav 1, hvor celecoxib foreligger i neutral form.
3. Farmaceutisk sammensætning ifølge krav 1, hvor det molekylære forhold mellem (rac)-tramadol-FICI og celecoxib er et molforhold på 1:1.
4. Farmaceutisk sammensætning ifølge et hvilket som helst af kravene 1 eller 3 til anvendelse som et analgetikum eller til anvendelse i behandling af smerte, fortrinsvis akut smerte, kronisk smerte, neuropatisk smerte, nociceptiv smerte, mild og svær til moderat smerte, hyperalgesi, smerte relateret til central sensibilisering, allodyni eller cancersmerte, herunder diabetisk neuropati eller diabetisk perifer neuropati og osteoarthritis, fibromyalgi, rheumatoid arthritis, ankyloserende spondylitis, frossen skulder eller iskias.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09384004A EP2311446A1 (en) | 2009-10-16 | 2009-10-16 | Compositions comprising Tramadol and Celecoxib in the treatment of pain |
| PCT/EP2010/006317 WO2011045075A1 (en) | 2009-10-16 | 2010-10-15 | Compositions comprising tramadol and celecoxib in the treatment of pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2488170T3 true DK2488170T3 (da) | 2014-03-03 |
Family
ID=41566149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10765762.9T DK2488170T3 (da) | 2009-10-16 | 2010-10-15 | Sammensætninger, der omfatter tramadol og celecoxib, til behandling af smerter |
Country Status (34)
| Country | Link |
|---|---|
| US (3) | US8569271B2 (da) |
| EP (3) | EP2311446A1 (da) |
| JP (2) | JP5579858B2 (da) |
| KR (1) | KR101688996B1 (da) |
| CN (2) | CN107050006A (da) |
| AR (1) | AR078653A1 (da) |
| AU (1) | AU2010306114B2 (da) |
| BR (1) | BR112012005044B8 (da) |
| CA (1) | CA2771651C (da) |
| CO (1) | CO6511249A2 (da) |
| CY (1) | CY1114960T1 (da) |
| DK (1) | DK2488170T3 (da) |
| EC (1) | ECSP12011735A (da) |
| ES (1) | ES2450615T3 (da) |
| HK (1) | HK1173379A1 (da) |
| HR (1) | HRP20140157T1 (da) |
| IL (1) | IL218096A (da) |
| IN (1) | IN2012DN01434A (da) |
| MA (1) | MA33743B1 (da) |
| MX (1) | MX2012003051A (da) |
| MY (1) | MY156275A (da) |
| NZ (1) | NZ598361A (da) |
| PL (1) | PL2488170T3 (da) |
| PT (1) | PT2488170E (da) |
| RS (1) | RS53202B (da) |
| RU (2) | RU2012120087A (da) |
| SG (1) | SG178833A1 (da) |
| SI (1) | SI2488170T1 (da) |
| SM (1) | SMT201400035B (da) |
| TN (1) | TN2012000059A1 (da) |
| TW (1) | TWI466668B (da) |
| UA (1) | UA108213C2 (da) |
| WO (1) | WO2011045075A1 (da) |
| ZA (1) | ZA201202151B (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2177215A1 (en) | 2008-10-17 | 2010-04-21 | Laboratorios Del. Dr. Esteve, S.A. | Co-crystals of tramadol and NSAIDs |
| US8746719B2 (en) * | 2010-08-03 | 2014-06-10 | Polaris Industries Inc. | Side-by-side vehicle |
| KR20140145948A (ko) * | 2011-04-05 | 2014-12-24 | 옵토솔브 엘엘피 | 안과 치료제 |
| JP5855770B2 (ja) * | 2012-02-06 | 2016-02-09 | プリジェン，ウィリアム，エル． | ファムシクロビルとセレコキシブとの組合せを含む、機能性身体症候群のための抗ウイルス化合物とｃｏｘ−２インヒビターとの組合せ療法 |
| WO2016116942A1 (en) | 2015-01-20 | 2016-07-28 | Anlon Chemical Research Organization | Novel pharmaceutical compounds comprising ticagrelor with salts of aspirin |
| CN114209707A (zh) * | 2015-05-28 | 2022-03-22 | 瑞迪博士实验室有限公司 | 用于治疗疼痛的塞来昔布口服组合物 |
| KR101710792B1 (ko) * | 2015-07-14 | 2017-02-28 | 주식회사 유영제약 | 세레콕시브 및 트라마돌을 함유하는 약제학적 조성물 |
| MX2016006464A (es) * | 2016-05-18 | 2017-11-17 | Laboratorios Liomont S A De C V | Composicion farmaceutica de una combinacion de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor. |
| WO2017208069A2 (en) * | 2016-05-27 | 2017-12-07 | Dr. Reddy's Laboratories Ltd. | Oral composition of celecoxib for treatment of pain |
| WO2018186650A2 (ko) * | 2017-04-03 | 2018-10-11 | 주식회사 킴스헬스케어 | 트라마돌과 셀레콕시브를 포함한 경구투여용 이중 복합정제 |
| KR102033716B1 (ko) * | 2017-04-03 | 2019-10-17 | 주식회사 킴스헬스케어 | 트라마돌과 셀레콕시브를 포함한 경구투여용 이중 복합정제 |
| KR102631399B1 (ko) | 2018-03-30 | 2024-02-01 | 씨지인바이츠 주식회사 | 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물 |
| MX2021013123A (es) * | 2019-05-14 | 2021-11-18 | Esteve Pharmaceuticals Sa | Uso de co-cristales de tramadol y celecoxib para el tratamiento del dolor mientras se reduce la responsabilidad por abuso de tramadol. |
| CN112007024A (zh) * | 2019-05-28 | 2020-12-01 | 江苏恒瑞医药股份有限公司 | 艾瑞昔布与曲马多联合在制备治疗疼痛的药物中的用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU661723B2 (en) | 1991-10-30 | 1995-08-03 | Mcneilab, Inc. | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug |
| US5516803A (en) | 1991-10-30 | 1996-05-14 | Mcneilab, Inc. | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug |
| RS49982B (sr) * | 1997-09-17 | 2008-09-29 | Euro-Celtique S.A., | Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2 |
| NZ513924A (en) * | 1999-03-01 | 2001-09-28 | Ortho Mcneil Pharm Inc | Composition comprising a tramadol material and a selective cox-2 inhibitor drug |
| DE19927688A1 (de) | 1999-06-17 | 2000-12-21 | Gruenenthal Gmbh | Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac |
| US7790905B2 (en) * | 2002-02-15 | 2010-09-07 | Mcneil-Ppc, Inc. | Pharmaceutical propylene glycol solvate compositions |
| ATE524186T1 (de) * | 2002-02-19 | 2011-09-15 | Adcock Ingram Ltd | Pharmazeutische kombinationen bestehend aus meloxicam, tramadol und paracetamol |
| US20080031950A1 (en) * | 2007-04-27 | 2008-02-07 | Nectid Inc. | Novel anelgesic combination |
| JP5399564B2 (ja) | 2009-10-16 | 2014-01-29 | ラボラトリオス・デル・デエレ・エステベ・エセ・ア | トラマドールとコキシブとの共結晶 |
| EP2392319A1 (en) | 2010-06-04 | 2011-12-07 | Laboratorios Del. Dr. Esteve, S.A. | Pharmaceutical compositions of co-crystals of tramadol and coxibs |
-
2009
- 2009-10-16 EP EP09384004A patent/EP2311446A1/en not_active Withdrawn
-
2010
- 2010-10-14 TW TW99134996A patent/TWI466668B/zh active
- 2010-10-15 MX MX2012003051A patent/MX2012003051A/es active IP Right Grant
- 2010-10-15 CA CA2771651A patent/CA2771651C/en active Active
- 2010-10-15 SI SI201030545T patent/SI2488170T1/sl unknown
- 2010-10-15 PT PT107657629T patent/PT2488170E/pt unknown
- 2010-10-15 BR BR112012005044A patent/BR112012005044B8/pt active IP Right Grant
- 2010-10-15 AR ARP100103776A patent/AR078653A1/es not_active Application Discontinuation
- 2010-10-15 CN CN201611195215.9A patent/CN107050006A/zh active Pending
- 2010-10-15 ES ES10765762.9T patent/ES2450615T3/es active Active
- 2010-10-15 DK DK10765762.9T patent/DK2488170T3/da active
- 2010-10-15 CN CN2010800463605A patent/CN102573824A/zh active Pending
- 2010-10-15 UA UAA201205897A patent/UA108213C2/uk unknown
- 2010-10-15 SG SG2012010898A patent/SG178833A1/en unknown
- 2010-10-15 RS RS20140100A patent/RS53202B/en unknown
- 2010-10-15 RU RU2012120087/15A patent/RU2012120087A/ru unknown
- 2010-10-15 AU AU2010306114A patent/AU2010306114B2/en active Active
- 2010-10-15 JP JP2012533530A patent/JP5579858B2/ja active Active
- 2010-10-15 RU RU2016125895A patent/RU2707752C2/ru active
- 2010-10-15 EP EP13005822.5A patent/EP2737898A1/en not_active Withdrawn
- 2010-10-15 US US13/394,995 patent/US8569271B2/en active Active
- 2010-10-15 KR KR1020127009600A patent/KR101688996B1/ko active IP Right Review Request
- 2010-10-15 NZ NZ598361A patent/NZ598361A/en unknown
- 2010-10-15 IN IN1434DEN2012 patent/IN2012DN01434A/en unknown
- 2010-10-15 PL PL10765762T patent/PL2488170T3/pl unknown
- 2010-10-15 EP EP10765762.9A patent/EP2488170B1/en active Active
- 2010-10-15 MY MYPI2012000614A patent/MY156275A/en unknown
- 2010-10-15 WO PCT/EP2010/006317 patent/WO2011045075A1/en active Application Filing
-
2012
- 2012-02-10 TN TNP2012000059A patent/TN2012000059A1/en unknown
- 2012-02-14 IL IL218096A patent/IL218096A/en active IP Right Grant
- 2012-03-16 CO CO12046133A patent/CO6511249A2/es active IP Right Grant
- 2012-03-19 EC ECSP12011735 patent/ECSP12011735A/es unknown
- 2012-03-23 ZA ZA2012/02151A patent/ZA201202151B/en unknown
- 2012-05-11 MA MA34860A patent/MA33743B1/fr unknown
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2013
- 2013-01-17 HK HK13100719.5A patent/HK1173379A1/xx unknown
- 2013-09-25 US US14/036,828 patent/US20140024622A1/en not_active Abandoned
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2014
- 2014-02-19 HR HRP20140157AT patent/HRP20140157T1/hr unknown
- 2014-03-10 CY CY20141100195T patent/CY1114960T1/el unknown
- 2014-03-20 SM SM201400035T patent/SMT201400035B/xx unknown
- 2014-07-09 JP JP2014141720A patent/JP2014221797A/ja not_active Withdrawn
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2015
- 2015-02-04 US US14/613,475 patent/US20150150889A1/en not_active Abandoned
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