DK2424523T3 - Sublingual sprayformulering med dihydroartemisinin - Google Patents
Sublingual sprayformulering med dihydroartemisininInfo
- Publication number
- DK2424523T3 DK2424523T3 DK10715337.1T DK10715337T DK2424523T3 DK 2424523 T3 DK2424523 T3 DK 2424523T3 DK 10715337 T DK10715337 T DK 10715337T DK 2424523 T3 DK2424523 T3 DK 2424523T3
- Authority
- DK
- Denmark
- Prior art keywords
- dihydroartemisinin
- spray formulation
- sublingual spray
- sublingual
- formulation
- Prior art date
Links
- BJDCWCLMFKKGEE-ISOSDAIHSA-N artenimol Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2O[C@H](O)[C@@H]4C BJDCWCLMFKKGEE-ISOSDAIHSA-N 0.000 title 1
- 229960002521 artenimol Drugs 0.000 title 1
- 229930016266 dihydroartemisinin Natural products 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000007921 spray Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2009/050415 WO2010122275A1 (en) | 2009-04-23 | 2009-04-23 | Pharmaceutical preparation |
| GB0906971.7A GB2469791B (en) | 2009-04-23 | 2009-04-23 | Transmucosal formulation of compounds providing dihydroartemesinin for use in the treatment of neoplastic disease |
| PCT/GB2010/050672 WO2010122356A1 (en) | 2009-04-23 | 2010-04-23 | Sublingual spray formulation comprising dihydroartemesinin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2424523T3 true DK2424523T3 (da) | 2012-09-24 |
Family
ID=42244197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10715337.1T DK2424523T3 (da) | 2009-04-23 | 2010-04-23 | Sublingual sprayformulering med dihydroartemisinin |
Country Status (23)
| Country | Link |
|---|---|
| US (4) | US20120157518A1 (enExample) |
| EP (1) | EP2424523B1 (enExample) |
| JP (1) | JP5795760B2 (enExample) |
| CN (1) | CN102395362B (enExample) |
| AU (1) | AU2010240654C1 (enExample) |
| BR (1) | BRPI1014887A8 (enExample) |
| CA (1) | CA2756925A1 (enExample) |
| DK (1) | DK2424523T3 (enExample) |
| ES (1) | ES2390046T3 (enExample) |
| HR (1) | HRP20120711T1 (enExample) |
| IL (1) | IL215453A (enExample) |
| ME (1) | ME02008B (enExample) |
| MX (1) | MX2011010961A (enExample) |
| MY (1) | MY155646A (enExample) |
| NZ (1) | NZ595469A (enExample) |
| PL (1) | PL2424523T3 (enExample) |
| PT (1) | PT2424523E (enExample) |
| RS (1) | RS52430B (enExample) |
| RU (1) | RU2501550C2 (enExample) |
| SG (1) | SG175162A1 (enExample) |
| SI (1) | SI2424523T1 (enExample) |
| WO (1) | WO2010122356A1 (enExample) |
| ZA (1) | ZA201107088B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0720967D0 (en) * | 2007-10-25 | 2007-12-05 | Protophama Ltd | Anti-material pharmaceutical composition |
| CA2756879A1 (en) * | 2009-04-23 | 2010-10-28 | Londonpharma Ltd. | Sublingual pharmaceutical composition comprising a neutral oil |
| CA2898113C (en) * | 2013-01-14 | 2022-05-31 | Health Clinics Limited | Combination cancer therapeutics and uses thereof |
| US20170326102A1 (en) | 2014-11-27 | 2017-11-16 | Cipla Limited | Pharmaceutical Composition Comprising an Artemisinin Derivative for Nasal or Pulmonary Delivery |
| JP2020033304A (ja) * | 2018-08-30 | 2020-03-05 | 医療法人ふじいやさか | 薬剤又はサプリメント、組成物、及び水素供給器の使用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030082107A1 (en) * | 1997-10-01 | 2003-05-01 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer |
| CH692321A5 (de) * | 1997-11-03 | 2002-05-15 | Mepha Ag | Pharmazeutisch wirksame Zusammensetzung, welche eine gegen Malariaparasiten wirksame Substanz enthält. |
| NZ509324A (en) * | 1998-07-14 | 2003-07-25 | Bayer Ag | Antiparasitic artemisinin derivatives (endoperoxides) |
| EP1351678A2 (en) * | 2001-01-02 | 2003-10-15 | Elizabeth Shanahan-Prendergast | Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens |
| US20060257463A1 (en) * | 2002-05-31 | 2006-11-16 | University Of Mississippi | Transmucosal delivery of cannabinoids |
| JP2005529938A (ja) * | 2002-06-06 | 2005-10-06 | ユニバーシティ オブ ワシントン | 癌の発症を予防または遅延するためのアルテミシニン様化合物を使用する方法 |
| WO2004075921A1 (en) * | 2003-02-26 | 2004-09-10 | Vrije Universiteit Brussel | Inclusion complex of artemisinin or derivates thereof with cyclodextrins |
| US20060084675A1 (en) * | 2004-10-18 | 2006-04-20 | Thomas Efferth | Combined treatment with artesunate and an epidermal growth factor receptor kinase inhibitor |
| US20060233895A1 (en) * | 2005-04-15 | 2006-10-19 | Brown Paul R | Herbal remedy for treating Lyme disease |
| ATE544444T1 (de) * | 2005-10-11 | 2012-02-15 | Yissum Res Dev Co | Zusammensetzungen für die nasale abgabe |
| CN100418524C (zh) * | 2005-10-26 | 2008-09-17 | 重庆医药工业研究院有限责任公司 | 一种稳定的青蒿素及青蒿素衍生物的药物组合物 |
-
2010
- 2010-04-23 DK DK10715337.1T patent/DK2424523T3/da active
- 2010-04-23 SI SI201030076T patent/SI2424523T1/sl unknown
- 2010-04-23 CN CN201080017965.1A patent/CN102395362B/zh not_active Expired - Fee Related
- 2010-04-23 EP EP10715337A patent/EP2424523B1/en active Active
- 2010-04-23 ES ES10715337T patent/ES2390046T3/es active Active
- 2010-04-23 RS RS20120393A patent/RS52430B/sr unknown
- 2010-04-23 MX MX2011010961A patent/MX2011010961A/es active IP Right Grant
- 2010-04-23 MY MYPI2011005080A patent/MY155646A/en unknown
- 2010-04-23 SG SG2011073954A patent/SG175162A1/en unknown
- 2010-04-23 PL PL10715337T patent/PL2424523T3/pl unknown
- 2010-04-23 US US13/265,518 patent/US20120157518A1/en not_active Abandoned
- 2010-04-23 HR HRP20120711AT patent/HRP20120711T1/hr unknown
- 2010-04-23 AU AU2010240654A patent/AU2010240654C1/en not_active Ceased
- 2010-04-23 WO PCT/GB2010/050672 patent/WO2010122356A1/en not_active Ceased
- 2010-04-23 RU RU2011139637/15A patent/RU2501550C2/ru active
- 2010-04-23 JP JP2012506584A patent/JP5795760B2/ja not_active Expired - Fee Related
- 2010-04-23 BR BRPI1014887A patent/BRPI1014887A8/pt not_active Application Discontinuation
- 2010-04-23 PT PT10715337T patent/PT2424523E/pt unknown
- 2010-04-23 CA CA2756925A patent/CA2756925A1/en not_active Abandoned
- 2010-04-23 NZ NZ595469A patent/NZ595469A/xx not_active IP Right Cessation
- 2010-04-23 ME MEP-2012-393A patent/ME02008B/me unknown
-
2011
- 2011-09-28 ZA ZA2011/07088A patent/ZA201107088B/en unknown
- 2011-10-02 IL IL215453A patent/IL215453A/en active IP Right Grant
-
2015
- 2015-07-30 US US14/813,424 patent/US20160022629A1/en not_active Abandoned
-
2017
- 2017-09-06 US US15/697,240 patent/US20170368023A1/en not_active Abandoned
-
2018
- 2018-10-18 US US16/164,610 patent/US20190142737A1/en not_active Abandoned
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