DK2373335T3 - Monoclonal anti-ferroportin 1 antibodies and uses thereof - Google Patents

Monoclonal anti-ferroportin 1 antibodies and uses thereof Download PDF

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Publication number
DK2373335T3
DK2373335T3 DK09760073.8T DK09760073T DK2373335T3 DK 2373335 T3 DK2373335 T3 DK 2373335T3 DK 09760073 T DK09760073 T DK 09760073T DK 2373335 T3 DK2373335 T3 DK 2373335T3
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DK
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Prior art keywords
ser
thr
val
gly
leu
Prior art date
Application number
DK09760073.8T
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Danish (da)
English (en)
Inventor
Peng Luan
Donmienne Doen Mun Leung
Joseph Vincent Manetta
Ying Tang
Derrick Ryan Witcher
Original Assignee
Lilly Co Eli
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Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK2373335T3 publication Critical patent/DK2373335T3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK09760073.8T 2008-12-05 2009-12-01 Monoclonal anti-ferroportin 1 antibodies and uses thereof DK2373335T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12007608P 2008-12-05 2008-12-05
US23981809P 2009-09-04 2009-09-04
PCT/US2009/066187 WO2010065496A1 (en) 2008-12-05 2009-12-01 Anti-ferroportin 1 monoclonal antibodies and uses thereof

Publications (1)

Publication Number Publication Date
DK2373335T3 true DK2373335T3 (en) 2016-05-02

Family

ID=41683589

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09760073.8T DK2373335T3 (en) 2008-12-05 2009-12-01 Monoclonal anti-ferroportin 1 antibodies and uses thereof

Country Status (25)

Country Link
EP (1) EP2373335B1 (https=)
JP (1) JP5713917B2 (https=)
KR (1) KR101353117B1 (https=)
CN (1) CN102238962B (https=)
AR (1) AR074398A1 (https=)
AU (1) AU2009322587B2 (https=)
BR (1) BRPI0922288A2 (https=)
CA (1) CA2745618C (https=)
CY (1) CY1117355T1 (https=)
DK (1) DK2373335T3 (https=)
EA (1) EA020472B1 (https=)
ES (1) ES2566343T3 (https=)
HR (1) HRP20160302T1 (https=)
HU (1) HUE028585T2 (https=)
IL (1) IL212731A0 (https=)
MX (1) MX2011005939A (https=)
NZ (1) NZ592545A (https=)
PA (1) PA8849601A1 (https=)
PL (1) PL2373335T3 (https=)
SG (1) SG171960A1 (https=)
SI (1) SI2373335T1 (https=)
TW (1) TW201023891A (https=)
UA (1) UA104741C2 (https=)
WO (1) WO2010065496A1 (https=)
ZA (1) ZA201103941B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2871116A1 (en) * 2012-05-14 2013-11-21 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US12263205B2 (en) 2018-04-30 2025-04-01 The Children's Hospital Of Philadelphia Methods of improving anemias by combining agents
CN114761013A (zh) 2019-09-27 2022-07-15 迪斯克医药公司 治疗骨髓纤维化和相关病症的方法
CN110806486B (zh) * 2019-11-23 2023-03-21 中南大学湘雅三医院 Mafg/as1/pcbp2/fpn1调控轴作为靶位点检测试剂的应用
WO2021231798A1 (en) 2020-05-13 2021-11-18 Disc Medicine, Inc. Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis
CN113980987A (zh) * 2021-12-06 2022-01-28 上海市农业科学院 一种提高植物抗镍性能的PgIREG1S和AlATP-PRTS双基因组及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7166448B1 (en) * 1999-05-10 2007-01-23 Children's Medical Center Corproation Ferroportin1 nucleic acids and proteins
IT1319221B1 (it) * 2000-10-17 2003-09-26 Antonello Pietrangelo Mutazioni nel gene della ferroportina 1 associata ad emocromatosiereditaria.
ES2500066T3 (es) * 2008-01-25 2014-09-30 Amgen, Inc Anticuerpos frente a ferroportina y métodos de uso

Also Published As

Publication number Publication date
CA2745618C (en) 2014-06-10
AR074398A1 (es) 2011-01-12
SI2373335T1 (sl) 2016-04-29
UA104741C2 (uk) 2014-03-11
ZA201103941B (en) 2012-11-28
CN102238962B (zh) 2014-02-12
EP2373335A1 (en) 2011-10-12
KR101353117B1 (ko) 2014-02-17
JP5713917B2 (ja) 2015-05-07
BRPI0922288A2 (pt) 2018-08-28
SG171960A1 (en) 2011-07-28
TW201023891A (en) 2010-07-01
CN102238962A (zh) 2011-11-09
NZ592545A (en) 2012-12-21
EA020472B1 (ru) 2014-11-28
HUE028585T2 (en) 2016-12-28
CA2745618A1 (en) 2010-06-10
HRP20160302T1 (hr) 2016-04-22
AU2009322587A1 (en) 2011-07-28
EA201170764A1 (ru) 2011-12-30
JP2012510814A (ja) 2012-05-17
KR20110084996A (ko) 2011-07-26
MX2011005939A (es) 2011-06-27
ES2566343T3 (es) 2016-04-12
HK1158977A1 (zh) 2012-07-27
PA8849601A1 (es) 2010-07-27
WO2010065496A1 (en) 2010-06-10
IL212731A0 (en) 2011-07-31
AU2009322587B2 (en) 2013-09-26
CY1117355T1 (el) 2017-04-26
PL2373335T3 (pl) 2016-08-31
EP2373335B1 (en) 2016-02-24

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