DK2365828T3 - Monoclonal antibodies against fibroblast second - Google Patents

Monoclonal antibodies against fibroblast second Download PDF

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Publication number
DK2365828T3
DK2365828T3 DK09825523.5T DK09825523T DK2365828T3 DK 2365828 T3 DK2365828 T3 DK 2365828T3 DK 09825523 T DK09825523 T DK 09825523T DK 2365828 T3 DK2365828 T3 DK 2365828T3
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mab
fgfr2
gal
human
mabs
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DK09825523.5T
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Danish (da)
English (en)
Inventor
Kyung Jin Kim
Wei-Meng Zhao
Hangil Park
Maximiliano Vasquez
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Galaxy Biotech Llc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK09825523.5T 2008-11-07 2009-11-06 Monoclonal antibodies against fibroblast second DK2365828T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11268608P 2008-11-07 2008-11-07
US16487009P 2009-03-30 2009-03-30
PCT/US2009/063647 WO2010054265A2 (en) 2008-11-07 2009-11-06 Monoclonal antibodies to fibroblast growth factor receptor 2

Publications (1)

Publication Number Publication Date
DK2365828T3 true DK2365828T3 (en) 2014-12-08

Family

ID=42153600

Family Applications (3)

Application Number Title Priority Date Filing Date
DK17191118.3T DK3290052T3 (da) 2008-11-07 2009-11-06 Monoklonale antistoffer mod fibroblastvækstfaktorreceptor 2
DK14188785.1T DK2842573T3 (en) 2008-11-07 2009-11-06 Monoclonal antibodies to fibroblast growth factor receptor 2
DK09825523.5T DK2365828T3 (en) 2008-11-07 2009-11-06 Monoclonal antibodies against fibroblast second

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK17191118.3T DK3290052T3 (da) 2008-11-07 2009-11-06 Monoklonale antistoffer mod fibroblastvækstfaktorreceptor 2
DK14188785.1T DK2842573T3 (en) 2008-11-07 2009-11-06 Monoclonal antibodies to fibroblast growth factor receptor 2

Country Status (20)

Country Link
US (8) US8101723B2 (cg-RX-API-DMAC7.html)
EP (4) EP3783024A1 (cg-RX-API-DMAC7.html)
JP (8) JP5627591B2 (cg-RX-API-DMAC7.html)
KR (1) KR101699432B1 (cg-RX-API-DMAC7.html)
CN (1) CN102131524B (cg-RX-API-DMAC7.html)
AU (1) AU2009313357B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0917315B8 (cg-RX-API-DMAC7.html)
CA (2) CA3166399A1 (cg-RX-API-DMAC7.html)
DK (3) DK3290052T3 (cg-RX-API-DMAC7.html)
ES (3) ES2646168T3 (cg-RX-API-DMAC7.html)
HR (2) HRP20171640T1 (cg-RX-API-DMAC7.html)
HU (1) HUE035700T2 (cg-RX-API-DMAC7.html)
LT (2) LT2842573T (cg-RX-API-DMAC7.html)
MX (1) MX2011000455A (cg-RX-API-DMAC7.html)
NO (1) NO2842573T3 (cg-RX-API-DMAC7.html)
PL (3) PL3290052T3 (cg-RX-API-DMAC7.html)
PT (3) PT2365828E (cg-RX-API-DMAC7.html)
RU (1) RU2546254C9 (cg-RX-API-DMAC7.html)
SI (2) SI3290052T1 (cg-RX-API-DMAC7.html)
WO (1) WO2010054265A2 (cg-RX-API-DMAC7.html)

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NO2842573T3 (cg-RX-API-DMAC7.html) 2018-02-24
US20100196364A1 (en) 2010-08-05
HUE035700T2 (en) 2018-05-28
US20190153105A1 (en) 2019-05-23
JP2022008996A (ja) 2022-01-14
HRP20171640T1 (hr) 2018-01-12
KR20110081141A (ko) 2011-07-13
US9382324B2 (en) 2016-07-05
JP6960485B2 (ja) 2021-11-05
EP2365828A2 (en) 2011-09-21
JP6661734B2 (ja) 2020-03-11
EP2365828B1 (en) 2014-10-15
ES2646168T3 (es) 2017-12-12
PL3290052T3 (pl) 2020-06-29
US20200347141A1 (en) 2020-11-05
PT2365828E (pt) 2014-12-12
EP3783024A1 (en) 2021-02-24
JP2012508184A (ja) 2012-04-05
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