DK2283156T3 - Detection of genetic predisposition to conditions associated with osteoarthritis - Google Patents
Detection of genetic predisposition to conditions associated with osteoarthritis Download PDFInfo
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- DK2283156T3 DK2283156T3 DK09740020.4T DK09740020T DK2283156T3 DK 2283156 T3 DK2283156 T3 DK 2283156T3 DK 09740020 T DK09740020 T DK 09740020T DK 2283156 T3 DK2283156 T3 DK 2283156T3
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C12Q2600/156—Polymorphic or mutational markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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| US20120115137A1 (en) * | 2010-08-31 | 2012-05-10 | Kornman Kenneth S | Methods of Predicting Osteoarthritis |
| CA2881024C (en) * | 2012-08-06 | 2021-06-15 | Christoph Hubertus LADEL | Genetic markers for predicting responsiveness to fgf-18 compound |
| PL2880181T3 (pl) * | 2012-08-06 | 2019-03-29 | Merck Patent Gmbh | Biomarkery prognostyczne w zaburzeniach chrząstki |
| JP2019503176A (ja) | 2016-01-12 | 2019-02-07 | インターロイキン ジェネティクス， インコーポレイテッド | 処置に対する応答を予測するための方法 |
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| DK3688468T3 (da) | 2017-09-29 | 2022-06-20 | Merck Patent Gmbh | Inflammatoriske biomarkører til forudsigelse af modtageligheden for fgf-18 forbindelse |
| DK3687558T3 (da) | 2017-09-29 | 2022-06-20 | Merck Patent Gmbh | Metaboliske biomarkører til forudsigelse af modtageligheden på fgf-18 forbindelse |
| IL281333B2 (en) * | 2018-09-10 | 2025-11-01 | Merck Patent Gmbh | A method for reducing risk in a clinical trial |
| US12370240B2 (en) | 2018-11-28 | 2025-07-29 | Genascence Corporation | Methods and compositions for treating osteoarthritis |
| CA3142662A1 (en) | 2019-06-06 | 2020-12-10 | Sitokine Limited | Compositions and methods for treating lung, colorectal and breast cancer |
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| FR2650840B1 (fr) | 1989-08-11 | 1991-11-29 | Bertin & Cie | Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications |
| US6004744A (en) | 1991-03-05 | 1999-12-21 | Molecular Tool, Inc. | Method for determining nucleotide identity through extension of immobilized primer |
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| US5942390A (en) | 1996-01-12 | 1999-08-24 | Cedars-Sinai Medical Center | Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism |
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| GB9621129D0 (en) * | 1996-10-10 | 1996-11-27 | Duff Gordon W | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| GB9706359D0 (en) * | 1997-03-27 | 1997-05-14 | Gemini International Holdings | Polymorphisms of an il-1 receptor antagonist gene |
| GB9711040D0 (en) * | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
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| CA2921196C (en) * | 2003-11-26 | 2019-03-05 | Celera Corporation | Single nucleotide polymorphisms associated with cardiovascular disorders and statin response, methods of detection and uses thereof |
| US20090253585A1 (en) * | 2005-11-30 | 2009-10-08 | Luda Diatchenko | Identification of Genetic Polymorphic Variants Associated With Somatosensory Disorders and Methods of Using the Same |
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| US9037472B2 (en) | 2012-04-20 | 2015-05-19 | Nuance Communications, Inc. | Method and system for facilitating communications for a user transaction |
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| JP6263499B2 (ja) | 2018-01-17 |
| ES2708826T3 (es) | 2019-04-11 |
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| EP3059323A1 (en) | 2016-08-24 |
| ES2561316T3 (es) | 2016-02-25 |
| CA2723239A1 (en) | 2009-11-05 |
| WO2009135218A3 (en) | 2010-04-01 |
| AU2009242490A1 (en) | 2009-11-05 |
| CA2723239C (en) | 2020-07-21 |
| JP2018038436A (ja) | 2018-03-15 |
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| US20100098775A1 (en) | 2010-04-22 |
| AU2009242490B2 (en) | 2015-01-22 |
| US20160340734A1 (en) | 2016-11-24 |
| EP3467126A1 (en) | 2019-04-10 |
| JP2015211677A (ja) | 2015-11-26 |
| JP2011520433A (ja) | 2011-07-21 |
| WO2009135218A2 (en) | 2009-11-05 |
| EP3059323B1 (en) | 2018-12-12 |
| EP2283156B1 (en) | 2015-11-11 |
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