DK225986A - Farmaceutisk komposition af promedikamenttypen og fremgangsmaade til fremstilling af samme - Google Patents

Farmaceutisk komposition af promedikamenttypen og fremgangsmaade til fremstilling af samme Download PDF

Info

Publication number
DK225986A
DK225986A DK225986A DK225986A DK225986A DK 225986 A DK225986 A DK 225986A DK 225986 A DK225986 A DK 225986A DK 225986 A DK225986 A DK 225986A DK 225986 A DK225986 A DK 225986A
Authority
DK
Denmark
Prior art keywords
prodrug
compounds
pharmaceutical composition
preparation
pharmaceutical compositions
Prior art date
Application number
DK225986A
Other languages
Danish (da)
English (en)
Other versions
DK225986D0 (da
Inventor
Frans Herwig Jan Jansen
Etienne Jacquy De Cock
Original Assignee
Ba Inpharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ba Inpharm Bv filed Critical Ba Inpharm Bv
Publication of DK225986D0 publication Critical patent/DK225986D0/da
Publication of DK225986A publication Critical patent/DK225986A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/54—Preparation of carboxylic acid anhydrides
    • C07C51/567—Preparation of carboxylic acid anhydrides by reactions not involving carboxylic acid anhydride groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/02—Saturated compounds containing hydroxy or O-metal groups
    • C07C62/06—Saturated compounds containing hydroxy or O-metal groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK225986A 1985-05-15 1986-05-15 Farmaceutisk komposition af promedikamenttypen og fremgangsmaade til fremstilling af samme DK225986A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8501408 1985-05-15

Publications (2)

Publication Number Publication Date
DK225986D0 DK225986D0 (da) 1986-05-15
DK225986A true DK225986A (da) 1986-11-16

Family

ID=19845998

Family Applications (1)

Application Number Title Priority Date Filing Date
DK225986A DK225986A (da) 1985-05-15 1986-05-15 Farmaceutisk komposition af promedikamenttypen og fremgangsmaade til fremstilling af samme

Country Status (10)

Country Link
US (1) US4863965A (fr)
EP (1) EP0202703B1 (fr)
JP (1) JPS61263916A (fr)
AT (1) ATE45284T1 (fr)
CA (1) CA1266828A (fr)
DE (1) DE3664869D1 (fr)
DK (1) DK225986A (fr)
FI (1) FI861971A (fr)
IL (1) IL80787A (fr)
NO (1) NO861903L (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991009831A1 (fr) * 1989-12-26 1991-07-11 Nova Pharmaceutical Corporation Anhydrides sous forme de promedicaments d'aspirine, d'indomethacine et d'ibuprofene, leur preparation, leurs compositions, et leur mode anti-inflammatoire d'emploi
ES2096614T3 (es) * 1990-12-06 1997-03-16 Hoechst Ag Derivados de acidos biliares, procedimiento para su preparacion y utilizacion de este compuesto como medicamento.
CA2108041A1 (fr) * 1991-03-29 1992-09-30 Nicholas S. Bodor Administration ciblee de medicaments par l'intermediaire d'un melange de derives phosphate
US6120751A (en) 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6090800A (en) * 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
EP1231209A1 (fr) * 2000-12-19 2002-08-14 Specialized Pharmaceutical Research Ltd. Co. Prodrugs von NSAIDs et de composés qui contiennent un groupement carboxy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2577699A (en) * 1949-09-10 1951-12-04 Bristol Lab Inc Penicillin anhydrides
US3763152A (en) * 1968-09-16 1973-10-02 American Home Prod Neutral cephalosporin anhydrides
US4206220A (en) * 1978-07-13 1980-06-03 Interx Research Corporation Prodrugs for the improved delivery of non-steroidal anti-inflammatory agents

Also Published As

Publication number Publication date
EP0202703B1 (fr) 1989-08-09
ATE45284T1 (de) 1989-08-15
IL80787A (en) 1991-08-16
FI861971A (fi) 1986-11-16
FI861971A0 (fi) 1986-05-12
CA1266828A (fr) 1990-03-20
NO861903L (no) 1986-11-17
JPS61263916A (ja) 1986-11-21
DE3664869D1 (en) 1989-09-14
US4863965A (en) 1989-09-05
EP0202703A1 (fr) 1986-11-26
DK225986D0 (da) 1986-05-15

Similar Documents

Publication Publication Date Title
US6417206B1 (en) Antitussive/antihist aminic/decongestant compositions
KR850001884B1 (ko) 수용성 벤조티아진 디옥시드염류의 제조방법
SE8302361D0 (sv) New tricyclic amines
US3624216A (en) 8-substituted theophyllines as anti-inflammatory agents
DK225986A (da) Farmaceutisk komposition af promedikamenttypen og fremgangsmaade til fremstilling af samme
EP0629400A1 (fr) Compositions contenant de l'idebenone pour le traitement de la maladie d'Alzheimer
EG19302A (en) Compound with gastric acid inhibitory effect and process for its preparation
JPH0475205B2 (fr)
US4892876A (en) Method for inhibiting HIV and an pharmaceutical composition therefor
KR900701278A (ko) 바이러스 감염 치료용 담즙산
DE50006842D1 (de) 4-benzylaminochinoline konjugate mit gallensaeure und ihre heteroanalogen, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und deren anwendung
US4189499A (en) Lysine 4-allyloxy-3-chlorophenylacetate and method of its preparation
FR2580648B1 (fr) Nouveaux derives du triazole, leur procede de preparation et les compositions pharmaceutiques les renfermant
EP0094412B1 (fr) Preparation et procedes medicaux
JPS6137731A (ja) グアバ葉エキスを有効成分とする経口糖尿病薬
JPH04312531A (ja) 悪性腫瘍転移抑制剤
US6528524B2 (en) Pharmaceutical compositions containing cinchonine dichlorhydrate
JP3173008B2 (ja) 肝疾患治療剤
DE3372772D1 (en) Quinazolinone derivatives, process for their preparation and their use in medicaments
KR890009919A (ko) 4- 헤테로아릴-1,3- 벤조디아제핀 및 2-치환된-α-(헤테로아릴) 벤젠에탄아민, 이의 제조방법 및 약제로서의 이의 용도
CA1307740C (fr) Preparation pharmaceutique et methode permettant d'inhiber la replication du htlv-iii (sida)
RU93005013A (ru) 1-аминоспиро[изохинолин-4(1н)3-пирролидин-1,2,3,5'(2н)-тетроны] и их аналоги, способ их получения и фармацевтическая композиция
FR3108503A1 (fr) Composition pharmaceutique active contre une infection virale du type coronavirus
FR2728466A1 (fr) Utilisation d'un extrait de tripterygium wilfordii hook f et de ses composants pour le traitement du melanome cancereux
KR950700063A (ko) 외상후 스트레스 치료제로서의 브로파로민(Brofaromine as an agent for treating post-traumatic stress)

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment