DK2240578T3 - I alt væsentligt dyreproteinfrit rekombinant furin og fremgangsmåder til fremstilling af samme - Google Patents

I alt væsentligt dyreproteinfrit rekombinant furin og fremgangsmåder til fremstilling af samme Download PDF

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Publication number
DK2240578T3
DK2240578T3 DK08869658.8T DK08869658T DK2240578T3 DK 2240578 T3 DK2240578 T3 DK 2240578T3 DK 08869658 T DK08869658 T DK 08869658T DK 2240578 T3 DK2240578 T3 DK 2240578T3
Authority
DK
Denmark
Prior art keywords
manufacture
methods
free recombinant
recombinant furin
deposit free
Prior art date
Application number
DK08869658.8T
Other languages
English (en)
Inventor
Roland Geyer
Artur Mitterer
Manfred Reiter
Meinhard Hasslacher
Barbara Plaimauer
Fircks Simone Von
Leopold Grillberger
Original Assignee
Baxalta GmbH
Baxalta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40524590&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2240578(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baxalta GmbH, Baxalta Inc filed Critical Baxalta GmbH
Application granted granted Critical
Publication of DK2240578T3 publication Critical patent/DK2240578T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6454—Dibasic site splicing serine proteases, e.g. kexin (3.4.21.61); furin (3.4.21.75) and other proprotein convertases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK08869658.8T 2007-12-31 2008-12-19 I alt væsentligt dyreproteinfrit rekombinant furin og fremgangsmåder til fremstilling af samme DK2240578T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1815207P 2007-12-31 2007-12-31
PCT/US2008/087732 WO2009088713A1 (en) 2007-12-31 2008-12-19 Substantially animal protein-free recombinant furin and methods for producing same

Publications (1)

Publication Number Publication Date
DK2240578T3 true DK2240578T3 (da) 2019-06-17

Family

ID=40524590

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08869658.8T DK2240578T3 (da) 2007-12-31 2008-12-19 I alt væsentligt dyreproteinfrit rekombinant furin og fremgangsmåder til fremstilling af samme

Country Status (18)

Country Link
US (2) US20090181423A1 (da)
EP (2) EP2240578B1 (da)
JP (2) JP5806465B2 (da)
KR (1) KR101618144B1 (da)
CN (2) CN110066782B (da)
AR (2) AR069892A1 (da)
AU (1) AU2008346817B2 (da)
BR (1) BRPI0821467B8 (da)
CA (1) CA2710260C (da)
DK (1) DK2240578T3 (da)
ES (2) ES2897561T3 (da)
HU (1) HUE043863T2 (da)
MX (1) MX2010007344A (da)
NZ (1) NZ586411A (da)
PL (2) PL3521422T3 (da)
PT (1) PT2240578T (da)
SG (2) SG192471A1 (da)
WO (1) WO2009088713A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2157177T3 (da) * 2007-05-22 2013-06-24 Baxter Int Fremgangsmåde til præparativ oprensning af humant furin
DK2240578T3 (da) 2007-12-31 2019-06-17 Baxalta GmbH I alt væsentligt dyreproteinfrit rekombinant furin og fremgangsmåder til fremstilling af samme
US8241623B1 (en) 2009-02-09 2012-08-14 David Bermudes Protease sensitivity expression system
BR112013000515B1 (pt) 2010-07-08 2021-11-03 Takeda Pharmaceutical Company Limited Método para produzir uma composição de fator von willebrand recombinante (rvwf)
WO2012122611A1 (en) * 2011-03-11 2012-09-20 Universidade De São Paulo - Usp Method for the production of recombinant human factor viii
CA2837948C (en) * 2011-06-02 2018-08-21 Baxter International Inc. Formulations of recombinant furin
TWI666319B (zh) * 2014-08-12 2019-07-21 美商巴克斯歐塔公司 在分泌ｆｕｒｉｎ之哺乳動物表現系統中生產經完全加工且具功能性之因子Ｘ
BR112017013423B1 (pt) * 2014-12-22 2023-04-11 Genzyme Corporation Métodos para cultivo de célula de mamífero
WO2018234543A1 (en) * 2017-06-23 2018-12-27 Baxalta Incorporated PURIFICATION OF FACTOR VIII SUBSPECIES

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1815207A (en) 1929-01-18 1931-07-21 John H Moffat Vehicle parking and locking device
NL9000917A (nl) 1989-10-25 1991-05-16 Holland Biotechnology Farmaceutisch preparaat met endoproteolytische activiteit; werkwijze voor endoproteolytische processing van (precursor) eiwitten en voor de (micro) biologische bereiding van eiwitten.
CA2096418C (en) 1990-11-26 2001-11-20 Philip J. Barr Expression of pace in host cells and methods of use thereof
US5604201A (en) * 1993-01-08 1997-02-18 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non-Profit Organization Methods and reagents for inhibiting furin endoprotease
AT404838B (de) * 1995-11-24 1999-03-25 Immuno Ag Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen
AU4751697A (en) 1996-10-10 1998-05-05 Douglas Danner Animal cell culture media comprising plant-derived nutrients
AT407750B (de) 1999-02-19 2001-05-25 Immuno Ag Verfahren zur herstellung einer vwf-präparation
US6596526B1 (en) * 2000-06-09 2003-07-22 Baxter Aktiengesellschaft Furin polypeptides with improved characteristics
SE0103084D0 (sv) * 2001-09-14 2001-09-14 Amersham Pharm Biotech Ab Generation of ion exchange media
US20030091976A1 (en) * 2001-11-14 2003-05-15 Ciphergen Biosystems, Inc. Methods for monitoring polypeptide production and purification using surface enhanced laser desorption/ionization mass spectrometry
EP1520008B1 (en) * 2002-07-09 2012-09-05 Baxter International Inc. Animal protein free media for cultivation of cells
WO2005082483A1 (en) * 2004-02-27 2005-09-09 Ge Healthcare Bio-Sciences Ab A process for the purification of antibodies
PL2522717T3 (pl) * 2006-01-04 2014-08-29 Baxalta Inc Pożywki do hodowli komórkowych wolne od oligopeptydów
DK2157177T3 (da) 2007-05-22 2013-06-24 Baxter Int Fremgangsmåde til præparativ oprensning af humant furin
DK2240578T3 (da) 2007-12-31 2019-06-17 Baxalta GmbH I alt væsentligt dyreproteinfrit rekombinant furin og fremgangsmåder til fremstilling af samme
WO2013070520A2 (en) 2011-11-03 2013-05-16 Barson Composites Corporation Corrosion-resistant diffusion coatings

Also Published As

Publication number Publication date
BRPI0821467B1 (pt) 2019-10-15
EP2240578A1 (en) 2010-10-20
MX2010007344A (es) 2010-11-09
CN110066782B (zh) 2024-04-16
AR113492A2 (es) 2020-05-06
AU2008346817B2 (en) 2014-07-24
AR069892A1 (es) 2010-02-24
CA2710260A1 (en) 2009-07-16
EP2240578B1 (en) 2019-03-20
CA2710260C (en) 2023-07-11
BRPI0821467A2 (pt) 2014-10-14
JP2015154790A (ja) 2015-08-27
ES2735173T3 (es) 2019-12-16
JP5806465B2 (ja) 2015-11-10
KR20100114057A (ko) 2010-10-22
AU2008346817A1 (en) 2009-07-16
JP2011507550A (ja) 2011-03-10
SG192471A1 (en) 2013-08-30
SG10201805749QA (en) 2018-08-30
CN110066782A (zh) 2019-07-30
CN101910401A (zh) 2010-12-08
BRPI0821467B8 (pt) 2021-05-25
KR101618144B1 (ko) 2016-05-17
EP3521422A1 (en) 2019-08-07
US20110076719A1 (en) 2011-03-31
WO2009088713A1 (en) 2009-07-16
PL2240578T3 (pl) 2019-09-30
HUE043863T2 (hu) 2019-09-30
PL3521422T3 (pl) 2021-12-20
EP3521422B1 (en) 2021-10-06
ES2897561T3 (es) 2022-03-01
NZ586411A (en) 2012-06-29
PT2240578T (pt) 2019-06-19
US20090181423A1 (en) 2009-07-16
US9127264B2 (en) 2015-09-08

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