DK2229433T3 - Osteogen differentiering af knoglemarvsstamceller og mesenkymale stamceller under anvendelse af en kombination af vækstfaktorer - Google Patents

Osteogen differentiering af knoglemarvsstamceller og mesenkymale stamceller under anvendelse af en kombination af vækstfaktorer

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Publication number
DK2229433T3
DK2229433T3 DK09700353.7T DK09700353T DK2229433T3 DK 2229433 T3 DK2229433 T3 DK 2229433T3 DK 09700353 T DK09700353 T DK 09700353T DK 2229433 T3 DK2229433 T3 DK 2229433T3
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DK
Denmark
Prior art keywords
stem cells
mesenkymal
differentizing
osteogen
combination
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Application number
DK09700353.7T
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Danish (da)
English (en)
Inventor
Enrico Bastianelli
Xavier Pesesse
Cindy Badoer
Original Assignee
Bone Therapeutics Sa
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Filing date
Publication date
Application filed by Bone Therapeutics Sa filed Critical Bone Therapeutics Sa
Application granted granted Critical
Publication of DK2229433T3 publication Critical patent/DK2229433T3/da

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0664—Dental pulp stem cells, Dental follicle stem cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
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    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
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    • C12N5/0688—Cells from the lungs or the respiratory tract
    • C12N5/0689—Stem cells; Progenitors
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells

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DK09700353.7T 2008-01-11 2009-01-09 Osteogen differentiering af knoglemarvsstamceller og mesenkymale stamceller under anvendelse af en kombination af vækstfaktorer DK2229433T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08000458 2008-01-11
PCT/EP2009/050209 WO2009087213A1 (en) 2008-01-11 2009-01-09 Osteogenic differentiation of bone marrow stem cells and mesenchymal stem cells using a combination of growth factors

Publications (1)

Publication Number Publication Date
DK2229433T3 true DK2229433T3 (da) 2017-11-13

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ID=39415339

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DK09700353.7T DK2229433T3 (da) 2008-01-11 2009-01-09 Osteogen differentiering af knoglemarvsstamceller og mesenkymale stamceller under anvendelse af en kombination af vækstfaktorer

Country Status (13)

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US (3) US20100278788A1 (cg-RX-API-DMAC7.html)
EP (1) EP2229433B1 (cg-RX-API-DMAC7.html)
JP (1) JP5524079B2 (cg-RX-API-DMAC7.html)
KR (3) KR20100126680A (cg-RX-API-DMAC7.html)
CN (2) CN101945993A (cg-RX-API-DMAC7.html)
AU (2) AU2009203682B2 (cg-RX-API-DMAC7.html)
CA (1) CA2710571C (cg-RX-API-DMAC7.html)
DK (1) DK2229433T3 (cg-RX-API-DMAC7.html)
ES (1) ES2650235T3 (cg-RX-API-DMAC7.html)
NO (1) NO2229433T3 (cg-RX-API-DMAC7.html)
PL (1) PL2229433T3 (cg-RX-API-DMAC7.html)
PT (1) PT2229433T (cg-RX-API-DMAC7.html)
WO (1) WO2009087213A1 (cg-RX-API-DMAC7.html)

Families Citing this family (10)

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Publication number Priority date Publication date Assignee Title
CA2741426C (en) * 2008-10-31 2020-04-21 Meredith Hans Method and device for activating stem cells
EP4086338A1 (en) 2011-03-17 2022-11-09 Minerva Biotechnologies Corporation Method for making pluripotent stem cells
BE1020528A3 (fr) 2011-10-11 2013-12-03 Bone Therapeutics Sa Utilisations du facteur de croissance et differenciation 8 (gdf 8).
CN103998598A (zh) * 2011-10-17 2014-08-20 米纳瓦生物技术公司 用于干细胞增殖和诱导的培养基
CN107592789A (zh) * 2015-04-23 2018-01-16 骨治疗公司 治疗性细胞的体外保存
WO2018017538A1 (en) 2016-07-21 2018-01-25 Sanbio, Inc. Msc growth predictor assays
BR112020007775A2 (pt) 2017-10-20 2020-10-20 Bone Therapeutics Sa métodos para obter células derivadas de células-tronco mesenquimais (msc) a partir de msc, método para obter células derivadas de msc com propriedades de transplante aprimoradas a partir de msc, populações de células derivadas de msc e composição farmacêutica
WO2020064791A1 (en) 2018-09-25 2020-04-02 Bone Therapeutics Sa Methods for differentiating mesenchymal stem cells
US20210404961A1 (en) * 2018-09-25 2021-12-30 Bone Therapeutics S.A. Methods and uses for determining osteogenic potential of in vitro differentiated cells
CN111357990A (zh) * 2019-12-26 2020-07-03 浙江欧谱生物科技有限公司 增加骨量的保健食品组合物及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811094A (en) * 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
US5837539A (en) * 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5972703A (en) * 1994-08-12 1999-10-26 The Regents Of The University Of Michigan Bone precursor cells: compositions and methods
US5736396A (en) * 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
US5827740A (en) * 1996-07-30 1998-10-27 Osiris Therapeutics, Inc. Adipogenic differentiation of human mesenchymal stem cells
AU6144698A (en) * 1997-02-05 1998-08-25 Case Western Reserve University Stimulatory effects of bfgf and bmp-2 on osteogenic differentiation of mesenchymal stem cells
JP2007509609A (ja) * 2003-10-02 2007-04-19 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、ミシガン 幹細胞拘束および骨形成を誘導するヒト前立腺癌細胞因子
JP2006346420A (ja) * 2005-06-13 2006-12-28 Univ Nagoya 移植材料及び骨質改善剤
WO2007002210A2 (en) * 2005-06-20 2007-01-04 Bresagen, Inc. Embryonic stem cell culture compositions and methods of use thereof
TW200726474A (en) * 2005-07-15 2007-07-16 Cognate Therapeutics Inc The immunophenotype and immunogenicity of human adipose derived cells
PL1989295T3 (pl) * 2006-02-16 2021-02-22 Université Libre de Bruxelles Różnicowanie osteogenne komórek macierzystych szpiku kostnego oraz komórki i populacje osteoprogenitorowe lub osteoblastyczne

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Publication number Publication date
KR20100126680A (ko) 2010-12-02
AU2014204491B2 (en) 2016-03-24
KR101920128B1 (ko) 2018-11-19
ES2650235T3 (es) 2018-01-17
AU2014204491A1 (en) 2014-08-07
WO2009087213A1 (en) 2009-07-16
AU2009203682A1 (en) 2009-07-16
PL2229433T3 (pl) 2018-01-31
KR20160039699A (ko) 2016-04-11
JP5524079B2 (ja) 2014-06-18
NO2229433T3 (cg-RX-API-DMAC7.html) 2018-02-17
CA2710571C (en) 2017-11-07
EP2229433A1 (en) 2010-09-22
AU2009203682B2 (en) 2014-07-03
JP2011509656A (ja) 2011-03-31
PT2229433T (pt) 2017-12-12
US20100278788A1 (en) 2010-11-04
EP2229433B1 (en) 2017-09-20
CN101945993A (zh) 2011-01-12
CN104250633A (zh) 2014-12-31
CA2710571A1 (en) 2009-07-16
US20130266544A1 (en) 2013-10-10
KR20180086305A (ko) 2018-07-30
US20200407688A1 (en) 2020-12-31

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