DK2142570T3 - Anti-EpCam-antistof og anvendelser deraf - Google Patents
Anti-EpCam-antistof og anvendelser derafInfo
- Publication number
- DK2142570T3 DK2142570T3 DK08759374.5T DK08759374T DK2142570T3 DK 2142570 T3 DK2142570 T3 DK 2142570T3 DK 08759374 T DK08759374 T DK 08759374T DK 2142570 T3 DK2142570 T3 DK 2142570T3
- Authority
- DK
- Denmark
- Prior art keywords
- epcam antibody
- therapeutic
- designated
- high affinity
- shows high
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07105628 | 2007-04-04 | ||
| PCT/EP2008/053913 WO2008122551A2 (en) | 2007-04-04 | 2008-04-02 | Anti-epcam antibody and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2142570T3 true DK2142570T3 (da) | 2011-10-03 |
Family
ID=38458122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK08759374.5T DK2142570T3 (da) | 2007-04-04 | 2008-04-02 | Anti-EpCam-antistof og anvendelser deraf |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8318911B2 (enExample) |
| EP (1) | EP2142570B1 (enExample) |
| JP (1) | JP5631733B2 (enExample) |
| KR (1) | KR101683884B1 (enExample) |
| CN (1) | CN101970497B (enExample) |
| AT (1) | ATE512988T1 (enExample) |
| AU (1) | AU2008235566B2 (enExample) |
| BR (1) | BRPI0810096A8 (enExample) |
| CA (1) | CA2682296C (enExample) |
| CY (1) | CY1111819T1 (enExample) |
| DK (1) | DK2142570T3 (enExample) |
| EA (1) | EA023679B1 (enExample) |
| ES (1) | ES2367675T3 (enExample) |
| HR (1) | HRP20110620T1 (enExample) |
| IL (1) | IL201196A0 (enExample) |
| MX (1) | MX2009010444A (enExample) |
| PL (1) | PL2142570T3 (enExample) |
| PT (1) | PT2142570E (enExample) |
| RS (1) | RS52040B (enExample) |
| SI (1) | SI2142570T1 (enExample) |
| WO (1) | WO2008122551A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5686493B2 (ja) | 2003-01-24 | 2015-03-18 | ユニバーシティ・オブ・ユタＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｕｔａｈ | テロメアの長さを決定することによって死亡の危険性を予測する方法 |
| CN102439171B (zh) | 2008-12-22 | 2017-07-14 | 犹他大学研究基金会 | 单色多重定量pcr |
| GB0909904D0 (en) * | 2009-06-09 | 2009-07-22 | Affitech As | Product |
| EP3138581B1 (en) | 2011-03-17 | 2019-01-02 | The University of Birmingham | Re-directed immunotherapy |
| JP6400470B2 (ja) * | 2011-05-16 | 2018-10-03 | ジェネロン（シャンハイ）コーポレイション リミテッド | 多重特異性Ｆａｂ融合タンパク質および使用法 |
| CN107315086B (zh) * | 2011-06-29 | 2019-09-10 | 中央研究院 | 使用表面涂层对生物物质的捕获、纯化和释放 |
| EP2819695B1 (en) * | 2012-03-02 | 2018-06-27 | Academia Sinica | ANTI-EPITHELIAL CELL ADHESION MOLECULE (EpCAM) ANTIBODIES AND METHODS OF USE THEREOF |
| US9494500B2 (en) | 2012-10-29 | 2016-11-15 | Academia Sinica | Collection and concentration system for biologic substance of interest and use thereof |
| HK1220737A1 (zh) | 2013-05-22 | 2017-05-12 | Telomere Diagnostics, Inc. | 短端粒丰度的量度 |
| WO2015153816A2 (en) | 2014-04-01 | 2015-10-08 | Academia Sinica | Methods and systems for cancer diagnosis and prognosis |
| EP2998026B1 (en) | 2014-08-26 | 2024-01-17 | Academia Sinica | Collector architecture layout design |
| CA2971169A1 (en) | 2014-12-30 | 2016-07-07 | Telomere Diagnostics, Inc. | Multiplex quantitative pcr |
| WO2017023704A1 (en) * | 2015-07-31 | 2017-02-09 | Sutro Biopharma, Inc. | ANTI-EpCAM ANTIBODIES, COMPOSITIONS COMPRISING ANTI-EpCAM ANTIBODIES AND METHODS OF MAKING AND USING ANTI-EpCAM ANTIBODIES |
| US10107726B2 (en) | 2016-03-16 | 2018-10-23 | Cellmax, Ltd. | Collection of suspended cells using a transferable membrane |
| US11046782B2 (en) | 2016-03-30 | 2021-06-29 | Musc Foundation For Research Development | Methods for treatment and diagnosis of cancer by targeting glycoprotein A repetitions predominant (GARP) and for providing effective immunotherapy alone or in combination |
| AU2017301826A1 (en) | 2016-07-26 | 2019-03-14 | Tessa Therapeutics Ltd. | Chimeric antigen receptor |
| WO2020018964A1 (en) | 2018-07-20 | 2020-01-23 | Fred Hutchinson Cancer Research Center | Compositions and methods for controlled expression of antigen-specific receptors |
| EP3847196A4 (en) | 2018-09-07 | 2023-01-04 | ITabMed (HK) Limited | BISPECIFIC ANTIGEN BINDING PROTEINS AND USES THEREOF |
| CN119896730A (zh) | 2018-12-17 | 2025-04-29 | 雷维托普有限公司 | 双免疫细胞衔接物 |
| TW202039582A (zh) * | 2019-04-22 | 2020-11-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 抗ＥｐＣＡＭ抗體及其應用 |
| US11851499B2 (en) | 2019-06-11 | 2023-12-26 | Bioatla, Inc. | Conditionally active anti-EpCAM antibodies, antibody fragments, their immunoconjugates and uses thereof |
| CN110950959B (zh) * | 2020-02-25 | 2020-07-03 | 和铂医药(上海)有限责任公司 | 靶向EpCAM的抗体及其制备和应用 |
| CN112094350B (zh) * | 2020-06-01 | 2024-01-05 | 普众发现医药科技(上海)有限公司 | 可应用于肿瘤细胞捕获的小鼠抗细胞表面糖蛋白cd326的单克隆抗体 |
| JP7570653B2 (ja) * | 2020-08-19 | 2024-10-22 | ▲蘇▼州易慕峰生物科技有限公司 | ヒト化抗体、キメラ抗原受容体、核酸、ベクター、細胞及び応用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4675187A (en) | 1983-05-16 | 1987-06-23 | Bristol-Myers Company | BBM-1675, a new antibiotic complex |
| US5525338A (en) | 1992-08-21 | 1996-06-11 | Immunomedics, Inc. | Detection and therapy of lesions with biotin/avidin conjugates |
| IT1245748B (it) | 1990-12-21 | 1994-10-14 | Mini Ricerca Scient Tecnolog | Preparazione includente anticorpi monoclonali biotinilati, avidina e biotina, per la diagnosi di affezioni tumorali e suo impiego |
| US5578287A (en) * | 1992-06-09 | 1996-11-26 | Neorx Corporation | Three-step pretargeting methods using improved biotin-active agent |
| JP3427871B2 (ja) * | 1996-06-24 | 2003-07-22 | 戸田工業株式会社 | コバルト被着型針状磁性酸化鉄粒子粉末 |
| ITRM20010079A1 (it) | 2001-02-16 | 2002-08-16 | Sigma Tau Ind Farmaceuti | Amminoderivati della biotina e loro coniugati con chelanti macrociclici. |
| US20050180979A1 (en) * | 2004-02-13 | 2005-08-18 | Micromet Ag | Anti-EpCAM immunoglobulins |
| US7435804B2 (en) | 2004-10-19 | 2008-10-14 | Phage Biotechnology, Inc. | Method for obtaining single chain antibodies to human interferon α2b |
-
2008
- 2008-04-02 JP JP2010501503A patent/JP5631733B2/ja not_active Expired - Fee Related
- 2008-04-02 SI SI200830364T patent/SI2142570T1/sl unknown
- 2008-04-02 WO PCT/EP2008/053913 patent/WO2008122551A2/en not_active Ceased
- 2008-04-02 DK DK08759374.5T patent/DK2142570T3/da active
- 2008-04-02 PT PT08759374T patent/PT2142570E/pt unknown
- 2008-04-02 HR HR20110620T patent/HRP20110620T1/hr unknown
- 2008-04-02 KR KR1020097023099A patent/KR101683884B1/ko not_active Expired - Fee Related
- 2008-04-02 EP EP08759374A patent/EP2142570B1/en active Active
- 2008-04-02 PL PL08759374T patent/PL2142570T3/pl unknown
- 2008-04-02 EA EA200970923A patent/EA023679B1/ru not_active IP Right Cessation
- 2008-04-02 RS RS20110388A patent/RS52040B/sr unknown
- 2008-04-02 ES ES08759374T patent/ES2367675T3/es active Active
- 2008-04-02 CA CA2682296A patent/CA2682296C/en not_active Expired - Fee Related
- 2008-04-02 US US12/594,559 patent/US8318911B2/en not_active Expired - Fee Related
- 2008-04-02 BR BRPI0810096A patent/BRPI0810096A8/pt not_active Application Discontinuation
- 2008-04-02 MX MX2009010444A patent/MX2009010444A/es active IP Right Grant
- 2008-04-02 AU AU2008235566A patent/AU2008235566B2/en not_active Ceased
- 2008-04-02 CN CN200880015767.4A patent/CN101970497B/zh not_active Expired - Fee Related
- 2008-04-02 AT AT08759374T patent/ATE512988T1/de active
-
2009
- 2009-09-24 IL IL201196A patent/IL201196A0/en active IP Right Grant
-
2011
- 2011-09-06 CY CY20111100854T patent/CY1111819T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT2142570E (pt) | 2011-09-13 |
| CA2682296C (en) | 2017-02-28 |
| AU2008235566A1 (en) | 2008-10-16 |
| EA023679B1 (ru) | 2016-06-30 |
| BRPI0810096A2 (pt) | 2014-10-21 |
| BRPI0810096A8 (pt) | 2017-12-26 |
| CN101970497B (zh) | 2017-05-10 |
| SI2142570T1 (sl) | 2012-01-31 |
| WO2008122551A9 (en) | 2009-02-05 |
| KR101683884B1 (ko) | 2016-12-07 |
| EP2142570B1 (en) | 2011-06-15 |
| HRP20110620T1 (hr) | 2011-09-30 |
| RS52040B (sr) | 2012-04-30 |
| IL201196A0 (en) | 2010-05-17 |
| US20100092491A1 (en) | 2010-04-15 |
| KR20100016237A (ko) | 2010-02-12 |
| WO2008122551A3 (en) | 2008-12-04 |
| PL2142570T3 (pl) | 2011-11-30 |
| EP2142570A2 (en) | 2010-01-13 |
| EA200970923A1 (ru) | 2010-04-30 |
| ATE512988T1 (de) | 2011-07-15 |
| WO2008122551A2 (en) | 2008-10-16 |
| AU2008235566B2 (en) | 2013-06-06 |
| JP2010523096A (ja) | 2010-07-15 |
| CY1111819T1 (el) | 2015-10-07 |
| US8318911B2 (en) | 2012-11-27 |
| CA2682296A1 (en) | 2008-10-16 |
| JP5631733B2 (ja) | 2014-11-26 |
| CN101970497A (zh) | 2011-02-09 |
| MX2009010444A (es) | 2009-10-20 |
| ES2367675T3 (es) | 2011-11-07 |
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