DK2081945T3 - Selektiv reduktion af spinosynfaktorer et-J og et-L til spinetoram - Google Patents

Selektiv reduktion af spinosynfaktorer et-J og et-L til spinetoram Download PDF

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Publication number
DK2081945T3
DK2081945T3 DK07853088.8T DK07853088T DK2081945T3 DK 2081945 T3 DK2081945 T3 DK 2081945T3 DK 07853088 T DK07853088 T DK 07853088T DK 2081945 T3 DK2081945 T3 DK 2081945T3
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DK
Denmark
Prior art keywords
spinetoram
spinosyn
ethyl
hydrogenation
mixture
Prior art date
Application number
DK07853088.8T
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English (en)
Inventor
David E Podhorez
Gary A Roth
David C Molzahn
Timothy Adaway
Original Assignee
Dow Agrosciences Llc
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Publication date
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Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
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Publication of DK2081945T3 publication Critical patent/DK2081945T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Hydrogen, Water And Hydrids (AREA)

Claims (3)

1. Fremgangsmåde til fremstilling af spinetoram, omfattende: hydrogenering af en blanding indeholdende ca. 50-90 vægt-% 3'-0-ethyl-spinosyn J og ca. 50-10 vægt-% 3'-0-ethyl-spinosyn L, i et med vand blandbart organisk opløsningsmiddel, med hydrogengas ved et tryk på mellem 1,378 x 104 og 2,068 x 107 Pa (2 og 3000 psig), i nærværelse af en heterogen katalysator, der er i stand til selektivt at reducere 5,6-dobbeltbindingen i 3'-0-ethyl-spinosyn J, indtil 3'-0-ethyl-spinosyn J er omdannet til 3'-0-ethyl-5,6-dihydro-spinosyn J.
2. Fremgangsmåde ifølge krav 1, hvor opløsningsmidlet er isopropylalkohol.
3. Fremgangsmåde ifølge krav 1, hvor den heterogene katalysator er 5% Rh/-Al203 eller 5% Pd/C.
DK07853088.8T 2006-11-03 2007-11-02 Selektiv reduktion af spinosynfaktorer et-J og et-L til spinetoram DK2081945T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85673906P 2006-11-03 2006-11-03
PCT/US2007/023338 WO2008057520A1 (en) 2006-11-03 2007-11-02 Selective reduction of spinosyn factors et-j and et-l to spinetoram

Publications (1)

Publication Number Publication Date
DK2081945T3 true DK2081945T3 (da) 2015-04-07

Family

ID=39272829

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07853088.8T DK2081945T3 (da) 2006-11-03 2007-11-02 Selektiv reduktion af spinosynfaktorer et-J og et-L til spinetoram

Country Status (17)

Country Link
US (1) US7683161B2 (da)
EP (1) EP2081945B1 (da)
JP (1) JP5346295B2 (da)
CN (1) CN101535330B (da)
AR (1) AR063457A1 (da)
AU (1) AU2007317900B2 (da)
BR (1) BRPI0718128B8 (da)
CA (1) CA2668168C (da)
CO (1) CO6231041A2 (da)
DK (1) DK2081945T3 (da)
ES (1) ES2527095T3 (da)
HK (1) HK1134677A1 (da)
IL (1) IL198464A (da)
MX (1) MX2009004624A (da)
MY (1) MY152128A (da)
WO (1) WO2008057520A1 (da)
ZA (1) ZA200902539B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201041509A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041510A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041507A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity and methods for preparing same
TW201041508A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
UA108200C2 (uk) * 2009-05-08 2015-04-10 Лікарські форми та способи застосування ектопаразитоцидів
TWI510189B (zh) * 2009-06-19 2015-12-01 Lilly Co Eli 殺外寄生蟲之方法及調配物
JP2013518045A (ja) * 2010-01-25 2013-05-20 イーライ リリー アンド カンパニー ウマ科のウマバエの幼虫を内部抑制または処置する方法
CA2817001C (en) 2010-11-05 2015-09-29 Eli Lilly And Company Methods for inhibiting insect infestations
CN103300001B (zh) * 2012-05-31 2014-09-24 陕西上格之路生物科学有限公司 一种含乙基多杀菌素的杀虫组合物
CN102696603B (zh) * 2012-05-31 2013-11-20 陕西上格之路生物科学有限公司 一种含乙基多杀菌素的杀虫组合物
EA029116B1 (ru) 2012-11-14 2018-02-28 Эли Лилли Энд Компани Способы и составы для борьбы с эктопаразитами
CN102986707A (zh) * 2012-12-18 2013-03-27 北京燕化永乐农药有限公司 一种复配杀虫剂
CN103329902B (zh) * 2013-07-03 2014-12-24 江苏龙灯化学有限公司 一种含有乙基多杀菌素和杀虫单的杀虫组合物
CN105211064A (zh) * 2015-10-26 2016-01-06 广东省昆虫研究所 一种含乙基多杀菌素的白蚁饵剂
BR102017003580B1 (pt) 2016-03-04 2022-03-29 Dow Agrosciences Llc Sistema e processos para produzir spinetoram
CN117320551A (zh) 2021-05-14 2023-12-29 先正达农作物保护股份公司 种子处理组合物
WO2022238575A1 (en) 2021-05-14 2022-11-17 Syngenta Crop Protection Ag Insect, acarina and nematode pest control
WO2022268813A1 (en) 2021-06-24 2022-12-29 Syngenta Crop Protection Ag Insect, acarina and nematode pest control
WO2022268815A1 (en) 2021-06-24 2022-12-29 Syngenta Crop Protection Ag Insect, acarina and nematode pest control
WO2023105064A1 (en) 2021-12-10 2023-06-15 Syngenta Crop Protection Ag Insect, acarina and nematode pest control
CN114950516B (zh) * 2022-06-10 2023-06-13 康纳新型材料(杭州)有限公司 选择性还原多杀菌素j的催化剂及其工艺

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9608380A (pt) * 1995-06-14 1999-01-05 Dowelanco Modificações sintéticas para os compostos de espinosina
US6001981A (en) * 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds
TWI275592B (en) * 2001-03-21 2007-03-11 Dow Agrosciences Llc Synthetic derivatives of 21-butenyl and related spinosyns

Also Published As

Publication number Publication date
IL198464A0 (en) 2010-02-17
EP2081945A1 (en) 2009-07-29
CN101535330A (zh) 2009-09-16
BRPI0718128B8 (pt) 2022-06-28
JP2010509225A (ja) 2010-03-25
CA2668168A1 (en) 2008-05-15
HK1134677A1 (en) 2010-05-07
AR063457A1 (es) 2009-01-28
BRPI0718128B1 (pt) 2019-03-26
AU2007317900A1 (en) 2008-05-15
BRPI0718128A2 (pt) 2013-11-12
CO6231041A2 (es) 2010-12-20
ES2527095T3 (es) 2015-01-20
CN101535330B (zh) 2012-06-27
CA2668168C (en) 2014-07-08
ZA200902539B (en) 2010-07-28
US20080108800A1 (en) 2008-05-08
MY152128A (en) 2014-08-15
US7683161B2 (en) 2010-03-23
JP5346295B2 (ja) 2013-11-20
EP2081945B1 (en) 2014-12-24
MX2009004624A (es) 2009-10-19
AU2007317900B2 (en) 2012-01-19
IL198464A (en) 2013-04-30
WO2008057520A1 (en) 2008-05-15

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