DK206684A - 17-halogenethynylsteroider og fremgangsmaade til fremstilling af disse - Google Patents

17-halogenethynylsteroider og fremgangsmaade til fremstilling af disse Download PDF

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Publication number
DK206684A
DK206684A DK206684A DK206684A DK206684A DK 206684 A DK206684 A DK 206684A DK 206684 A DK206684 A DK 206684A DK 206684 A DK206684 A DK 206684A DK 206684 A DK206684 A DK 206684A
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DK
Denmark
Prior art keywords
carbon atoms
image
partial formula
halogenethylnylsteroids
preparing
Prior art date
Application number
DK206684A
Other languages
Danish (da)
English (en)
Other versions
DK206684D0 (da
Inventor
Helmut Hofmeister
Henry Laurent
Klaus Annen
Rudolf Wiechert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK206684D0 publication Critical patent/DK206684D0/da
Publication of DK206684A publication Critical patent/DK206684A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • C07J1/0088Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096Alkynyl derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK206684A 1983-04-25 1984-04-25 17-halogenethynylsteroider og fremgangsmaade til fremstilling af disse DK206684A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833315324 DE3315324A1 (de) 1983-04-25 1983-04-25 Verfahren zur herstellung von 17(alpha)-(br oder j)-ethinyl-17ss-or-steroiden

Publications (2)

Publication Number Publication Date
DK206684D0 DK206684D0 (da) 1984-04-25
DK206684A true DK206684A (da) 1984-10-26

Family

ID=6197529

Family Applications (1)

Application Number Title Priority Date Filing Date
DK206684A DK206684A (da) 1983-04-25 1984-04-25 17-halogenethynylsteroider og fremgangsmaade til fremstilling af disse

Country Status (15)

Country Link
US (1) US4567002A (es)
EP (1) EP0123241B1 (es)
JP (1) JPS6034990A (es)
AT (1) ATE41160T1 (es)
CA (1) CA1254883A (es)
CS (1) CS252474B2 (es)
DD (1) DD221460A5 (es)
DE (2) DE3315324A1 (es)
DK (1) DK206684A (es)
ES (1) ES531900A0 (es)
FI (1) FI841620A (es)
GR (1) GR81486B (es)
HU (1) HU193568B (es)
PL (1) PL143460B1 (es)
SU (1) SU1389681A3 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3434448A1 (de) * 1984-09-17 1986-03-27 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von pregnan-derivaten
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
CA2081205C (en) * 1990-06-11 2001-02-27 John W. Wilks Steroids which inhibit angiogenesis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3211725A (en) * 1960-04-20 1965-10-12 Merck & Co Inc 6alpha-methyl-21 halo nor ethisterones and intermediates in the preparation thereof
US3067214A (en) * 1960-04-20 1962-12-04 Merck & Co Inc Haloethisterone compounds
US3347880A (en) * 1962-10-05 1967-10-17 Schering Corp 17alpha-halogenoethinylestranes
DE2625306C2 (de) * 1976-06-02 1978-06-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Pregnan-Derivaten
DE3242892C1 (de) * 1982-11-16 1984-07-12 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 17alpha-(Br oder J)-ethinyl-17ss-hydroxysteroiden

Also Published As

Publication number Publication date
FI841620A0 (fi) 1984-04-25
DE3315324A1 (de) 1984-10-31
EP0123241A1 (de) 1984-10-31
DK206684D0 (da) 1984-04-25
ATE41160T1 (de) 1989-03-15
CA1254883A (en) 1989-05-30
SU1389681A3 (ru) 1988-04-15
PL143460B1 (en) 1988-02-29
JPS6034990A (ja) 1985-02-22
ES8506045A1 (es) 1985-07-01
DE3477000D1 (en) 1989-04-13
PL247376A1 (en) 1985-04-09
EP0123241B1 (de) 1989-03-08
CS307084A2 (en) 1987-01-15
CS252474B2 (en) 1987-09-17
DD221460A5 (de) 1985-04-24
GR81486B (es) 1984-12-11
ES531900A0 (es) 1985-07-01
HU193568B (en) 1987-10-28
HUT34215A (en) 1985-02-28
FI841620A (fi) 1984-10-26
US4567002A (en) 1986-01-28

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment