DK2049517T3 - Aminopiperidine derivatives as CETP inhibitors - Google Patents

Aminopiperidine derivatives as CETP inhibitors Download PDF

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Publication number
DK2049517T3
DK2049517T3 DK07786158.1T DK07786158T DK2049517T3 DK 2049517 T3 DK2049517 T3 DK 2049517T3 DK 07786158 T DK07786158 T DK 07786158T DK 2049517 T3 DK2049517 T3 DK 2049517T3
Authority
DK
Denmark
Prior art keywords
alkyl
mmol
benzyl
mixture
amino
Prior art date
Application number
DK07786158.1T
Other languages
Danish (da)
English (en)
Inventor
Hidetomo Imase
Yuki Iwaki
Toshio Kawanami
Takahiro Miyake
Muneto Mogi
Osamu Ohmori
Hongbo Qin
Ichiro Umemura
Ken Yamada
Kayo Yasoshima
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority claimed from PCT/EP2007/006384 external-priority patent/WO2008009435A1/en
Application granted granted Critical
Publication of DK2049517T3 publication Critical patent/DK2049517T3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
DK07786158.1T 2006-07-20 2007-07-18 Aminopiperidine derivatives as CETP inhibitors DK2049517T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06117541 2006-07-20
US88705807P 2007-01-29 2007-01-29
PCT/EP2007/006384 WO2008009435A1 (en) 2006-07-20 2007-07-18 Amino-piperidine derivatives as cetp inhibitors

Publications (1)

Publication Number Publication Date
DK2049517T3 true DK2049517T3 (en) 2014-03-03

Family

ID=37680601

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07786158.1T DK2049517T3 (en) 2006-07-20 2007-07-18 Aminopiperidine derivatives as CETP inhibitors

Country Status (13)

Country Link
KR (1) KR20120034774A (zh)
CN (1) CN101490035B (zh)
BR (1) BRPI0714516A2 (zh)
DK (1) DK2049517T3 (zh)
ES (1) ES2449571T3 (zh)
MY (1) MY153262A (zh)
NZ (1) NZ573439A (zh)
PT (1) PT2049517E (zh)
RU (1) RU2442782C2 (zh)
SG (1) SG173378A1 (zh)
SI (1) SI2049517T1 (zh)
UA (1) UA96942C2 (zh)
ZA (1) ZA200810008B (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112898257B (zh) * 2021-03-12 2023-01-24 天津理工大学 一种水溶性香豆素衍生物内盐的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2719311B1 (fr) * 1994-03-18 1998-06-26 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
US6140342A (en) * 1998-09-17 2000-10-31 Pfizer Inc. Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines

Also Published As

Publication number Publication date
ZA200810008B (en) 2009-11-25
NZ573439A (en) 2012-02-24
CN101490035A (zh) 2009-07-22
BRPI0714516A2 (pt) 2014-07-08
SI2049517T1 (sl) 2014-04-30
KR20120034774A (ko) 2012-04-12
MY153262A (en) 2015-01-29
PT2049517E (pt) 2014-03-10
ES2449571T3 (es) 2014-03-20
CN101490035B (zh) 2013-02-13
RU2442782C2 (ru) 2012-02-20
UA96942C2 (uk) 2011-12-26
RU2009105763A (ru) 2010-08-27
SG173378A1 (en) 2011-08-29

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