DK2017265T3 - Kondenserede forbindelser, som inhiberer vanilje-receptor-subtype-1 (VR1) - Google Patents

Kondenserede forbindelser, som inhiberer vanilje-receptor-subtype-1 (VR1)

Info

Publication number
DK2017265T3
DK2017265T3 DK08166079.7T DK08166079T DK2017265T3 DK 2017265 T3 DK2017265 T3 DK 2017265T3 DK 08166079 T DK08166079 T DK 08166079T DK 2017265 T3 DK2017265 T3 DK 2017265T3
Authority
DK
Denmark
Prior art keywords
vanilla
inhibit
compounds
receptor subtype
condensed compounds
Prior art date
Application number
DK08166079.7T
Other languages
English (en)
Inventor
Arthur Gomtsyan
Erol K Bayburt
Chih-Hung Lee
John R Koenig
Robert Schmidt
Kirill Lukin
Gilles Chambournier
Robert M Leanna
Russel D Cink
Margaret Hsu
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33555102&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2017265(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US10/459,925 external-priority patent/US7015233B2/en
Priority claimed from US10/864,068 external-priority patent/US7375126B2/en
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK2017265T3 publication Critical patent/DK2017265T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/06Anti-spasmodics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
DK08166079.7T 2003-06-12 2004-06-10 Kondenserede forbindelser, som inhiberer vanilje-receptor-subtype-1 (VR1) DK2017265T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/459,925 US7015233B2 (en) 2003-06-12 2003-06-12 Fused compounds that inhibit vanilloid subtype 1 (VR1) receptor
US10/864,068 US7375126B2 (en) 2003-06-12 2004-06-09 Fused compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
EP04754996A EP1658269B1 (en) 2003-06-12 2004-06-10 Fused compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor

Publications (1)

Publication Number Publication Date
DK2017265T3 true DK2017265T3 (da) 2011-09-19

Family

ID=33555102

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04754996T DK1658269T3 (da) 2003-06-12 2004-06-10 Kondenserede forbindelser som inhiberer vanilloidreceptorsubtype 1 (VR1)-receptoren
DK08166079.7T DK2017265T3 (da) 2003-06-12 2004-06-10 Kondenserede forbindelser, som inhiberer vanilje-receptor-subtype-1 (VR1)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK04754996T DK1658269T3 (da) 2003-06-12 2004-06-10 Kondenserede forbindelser som inhiberer vanilloidreceptorsubtype 1 (VR1)-receptoren

Country Status (21)

Country Link
EP (2) EP2017265B1 (da)
JP (2) JP4857113B2 (da)
KR (2) KR101138216B1 (da)
CN (1) CN102617464A (da)
AT (2) ATE411982T1 (da)
AU (2) AU2004247721C1 (da)
BR (1) BRPI0411116A (da)
CA (2) CA2526872C (da)
CY (2) CY1108713T1 (da)
DE (1) DE602004017329D1 (da)
DK (2) DK1658269T3 (da)
ES (1) ES2318308T3 (da)
HK (2) HK1093727A1 (da)
IL (4) IL172457A (da)
MX (1) MXPA05013550A (da)
NZ (3) NZ578264A (da)
PL (2) PL1658269T3 (da)
PT (2) PT1658269E (da)
SI (2) SI2017265T1 (da)
TW (3) TW201300361A (da)
WO (1) WO2004111009A1 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1608319A4 (en) 2003-04-03 2007-02-28 Univ California IMPROVED HEMMER FOR SOLUBLE EPOXY HYDROLASE
EP1765311A4 (en) 2004-03-16 2009-04-29 Univ California REDUCTION OF NEPHROPATHY WITH INHIBITORS OF SOLUBLE EPOXY HYDROLASE AND EPOXYEICOSANOIDS
AU2005295167B2 (en) 2004-10-20 2012-05-10 The Regents Of The University Of California Improved inhibitors for the soluble epoxide hydrolase
JP2008523072A (ja) 2004-12-07 2008-07-03 ルーカス ファーマシューティカルズ, インコーポレイテッド タンパク質キナーゼの阻害剤
JP2008523071A (ja) 2004-12-07 2008-07-03 ルーカス ファーマシューティカルズ, インコーポレイテッド Mapキナーゼの尿素インヒビター
EP1931681B1 (en) 2005-10-07 2012-11-14 Glenmark Pharmaceuticals S.A. Substituted benzofused derivatives and their use as vanilloid receptor ligands
US20070104780A1 (en) * 2005-10-25 2007-05-10 Lipari John M Formulation comprising a drug of low water solubility and method of use thereof
BRPI0617884A2 (pt) * 2005-10-28 2011-08-09 Abbott Lab derivados de indazol que inibem receptor trpv1
AR059826A1 (es) * 2006-03-13 2008-04-30 Univ California Inhibidores de urea conformacionalmente restringidos de epoxido hidrolasa soluble
NZ571706A (en) * 2006-04-18 2012-06-29 Abbott Lab Antagonists of the vanilloid receptor subtype 1 (VR1) and uses thereof
WO2009081222A1 (en) 2007-12-21 2009-07-02 Glenmark Pharmaceuticals, S.A. Substituted tricyclic pyridine or pyrimidine vanilloid receptor ligands
US8557872B2 (en) 2008-01-28 2013-10-15 Amorepacific Corporation Compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same
JP5438103B2 (ja) 2008-07-02 2014-03-12 アモーレパシフィック コーポレイション バニロイド受容体アンタゴニストとしての新規化合物、その異性体またはその薬学的に許容される塩、並びにそれを含む医薬組成物
AR073631A1 (es) * 2008-10-17 2010-11-17 Abbott Lab Antagonistas del receptor transitorio potencial de vanilloides 1 ( trpv1) utiles para tratar inflamacion y dolor
EP2528604B1 (en) 2010-01-29 2017-11-22 The Regents of the University of California Acyl piperidine inhibitors of soluble epoxide hydrolase
KR101960555B1 (ko) 2011-05-13 2019-03-20 어레이 바이오파마 인크. Trka 키나제 저해제로서의 피롤리디닐 유레아 및 피롤리디닐 티오유레아 화합물
MX2014013489A (es) * 2012-05-09 2015-02-12 Bayer Cropscience Ag 5-halogenopirazolindanil carboxamidas.
US9546156B2 (en) 2012-11-13 2017-01-17 Array Biopharma Inc. N-bicyclic aryl,N'-pyrazolyl urea, thiourea, guanidine cyanoguanidine compounds as TrkA kinase inhibitors
WO2014078408A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
WO2014078331A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. N-(arylalkyl)-n'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
DK2922844T3 (da) 2012-11-13 2018-03-05 Array Biopharma Inc N-pyrrolidinyl-, n'-pyrazolyl-urinstof-, thiourinstof-, guanidin- og cyanoguanidinforbindelser som trka-kinaseinhibitorer
US9790178B2 (en) 2012-11-13 2017-10-17 Array Biopharma Inc. Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
MX366761B (es) 2012-11-13 2019-07-23 Array Biopharma Inc Compuestos bíciclicos de urea, tiourea, guanidina y cianoguanidina útiles para el tratamiento del dolor.
US9809578B2 (en) 2012-11-13 2017-11-07 Array Biopharma Inc. Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trkA kinase inhibitors
WO2014078322A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
US9828360B2 (en) 2012-11-13 2017-11-28 Array Biopharma Inc. Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
WO2014078325A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. N-(monocyclic aryl),n'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
MA40434B1 (fr) 2014-05-15 2019-09-30 Array Biopharma Inc 1-((3s,4r)-4-(3-fluorophényl)-1-(2-méthoxyéthyl)pyrrolidin-3-yl)-3-(4-méthyl-3-(2-méthylpyrimidin-5-yl)-1-phényl-1h-pyrazol-5-yl)urée comme inhibiteur de la kinase trka
DE102022104759A1 (de) 2022-02-28 2023-08-31 SCi Kontor GmbH Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW536734B (en) * 2000-07-31 2003-06-11 Clariant Int Ltd Process for manufacturing a microelectronic device
CA2455754A1 (en) * 2001-07-31 2003-02-20 Bayer Healthcare Ag Amine derivatives
JP2003192587A (ja) * 2001-12-26 2003-07-09 Bayer Ag 尿素誘導体
DE60325834D1 (de) * 2002-02-20 2009-03-05 Abbott Lab Kondensierte azabicyclischeverbindungen als inhibitoren des vanilloid-rezeptors 1 (vr1)
GB0206876D0 (en) * 2002-03-22 2002-05-01 Merck Sharp & Dohme Therapeutic agents
AU2003241453A1 (en) * 2002-05-17 2003-12-02 Janssen Pharmaceutica N.V. Aminotetralin-derived urea modulators of vanilloid vr1 receptor

Also Published As

Publication number Publication date
TW201300361A (zh) 2013-01-01
AU2004247721A1 (en) 2004-12-23
NZ543713A (en) 2009-08-28
EP2017265A1 (en) 2009-01-21
SI2017265T1 (sl) 2011-09-30
NZ590234A (en) 2012-07-27
CA2526872C (en) 2013-02-05
KR101138216B1 (ko) 2012-09-05
IL216046A0 (en) 2011-12-29
MXPA05013550A (es) 2006-04-05
EP1658269B1 (en) 2008-10-22
AU2004247721C1 (en) 2011-12-22
KR20110089464A (ko) 2011-08-08
IL215997A0 (en) 2011-12-29
NZ578264A (en) 2011-02-25
WO2004111009A1 (en) 2004-12-23
HK1093727A1 (en) 2007-03-09
CA2756058A1 (en) 2004-12-23
KR101150324B1 (ko) 2012-06-13
DK1658269T3 (da) 2009-01-12
TW200509926A (en) 2005-03-16
TWI366461B (en) 2012-06-21
ATE510824T1 (de) 2011-06-15
PT1658269E (pt) 2009-01-09
SI1658269T1 (sl) 2009-04-30
CY1108713T1 (el) 2014-04-09
PT2017265E (pt) 2011-07-29
CN102617464A (zh) 2012-08-01
JP2007500753A (ja) 2007-01-18
TWI394569B (zh) 2013-05-01
EP2017265B1 (en) 2011-05-25
ES2318308T3 (es) 2009-05-01
CA2526872A1 (en) 2004-12-23
BRPI0411116A (pt) 2006-07-18
JP4857113B2 (ja) 2012-01-18
IL172457A (en) 2011-12-29
PL1658269T3 (pl) 2009-08-31
DE602004017329D1 (de) 2008-12-04
EP1658269A1 (en) 2006-05-24
HK1126488A1 (en) 2009-09-04
IL207335A (en) 2012-02-29
ATE411982T1 (de) 2008-11-15
TW201038269A (en) 2010-11-01
PL2017265T3 (pl) 2011-11-30
AU2010257277A1 (en) 2011-01-13
IL172457A0 (en) 2006-04-10
JP2011153148A (ja) 2011-08-11
AU2010257277B2 (en) 2011-08-18
CY1111945T1 (el) 2015-11-04
AU2004247721B2 (en) 2011-01-20
KR20060058769A (ko) 2006-05-30
IL207335A0 (en) 2010-12-30

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