DK1987159T4 - Fremgangsmåde til sekventering af en polynukleotidtemplate - Google Patents

Fremgangsmåde til sekventering af en polynukleotidtemplate Download PDF

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Publication number
DK1987159T4
DK1987159T4 DK07705178.7T DK07705178T DK1987159T4 DK 1987159 T4 DK1987159 T4 DK 1987159T4 DK 07705178 T DK07705178 T DK 07705178T DK 1987159 T4 DK1987159 T4 DK 1987159T4
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Denmark
Prior art keywords
polynucleotid
template
procedure
sequence
polynucleotid template
Prior art date
Application number
DK07705178.7T
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English (en)
Other versions
DK1987159T3 (da
Inventor
Eric Hans Vermaas
Graham John Worsley
Jonathan Mark Boutell
Colin Lloyd Barnes
Roberto Rigatti
Niall Anthony Gormley
Geoffrey Paul Smith
Vincent Peter Smith
Tobias William Barr Ost
David Bentley
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Illumina Cambridge Ltd
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37969705&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1987159(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Illumina Cambridge Ltd filed Critical Illumina Cambridge Ltd
Publication of DK1987159T3 publication Critical patent/DK1987159T3/da
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
DK07705178.7T 2006-02-08 2007-02-08 Fremgangsmåde til sekventering af en polynukleotidtemplate DK1987159T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77136106P 2006-02-08 2006-02-08
PCT/GB2007/000447 WO2007091077A1 (en) 2006-02-08 2007-02-08 Method for sequencing a polynucleotide template

Publications (2)

Publication Number Publication Date
DK1987159T3 DK1987159T3 (da) 2012-12-10
DK1987159T4 true DK1987159T4 (da) 2020-11-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK07705178.7T DK1987159T4 (da) 2006-02-08 2007-02-08 Fremgangsmåde til sekventering af en polynukleotidtemplate

Country Status (7)

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US (4) US8192930B2 (da)
EP (1) EP1987159B2 (da)
CN (1) CN101415839B (da)
CA (1) CA2641851A1 (da)
DK (1) DK1987159T4 (da)
SG (1) SG169356A1 (da)
WO (1) WO2007091077A1 (da)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE510024T1 (de) 2003-10-31 2011-06-15 Advanced Genetic Analysis Corp Ab Verfahren zur herstellung eines gepaarten tag aus einer nukleinsäuresequenz sowie verfahren zur verwendung davon
WO2006138257A2 (en) 2005-06-15 2006-12-28 Callida Genomics, Inc. Single molecule arrays for genetic and chemical analysis
GB0514910D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Method for sequencing a polynucleotide template
GB0514935D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Methods for sequencing a polynucleotide template
EP1969146B1 (en) * 2006-01-04 2010-10-06 Si Lok Methods for nucleic acid mapping and identification of fine-structural-variations in nucleic acids and utilities
WO2007091077A1 (en) * 2006-02-08 2007-08-16 Solexa Limited Method for sequencing a polynucleotide template
US7754429B2 (en) 2006-10-06 2010-07-13 Illumina Cambridge Limited Method for pair-wise sequencing a plurity of target polynucleotides
JP2010537643A (ja) * 2007-08-29 2010-12-09 アプライド バイオシステムズ， エルエルシー 代替的な核酸配列決定法
US20090093378A1 (en) * 2007-08-29 2009-04-09 Helen Bignell Method for sequencing a polynucleotide template
US8592150B2 (en) * 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
US9540637B2 (en) 2008-01-09 2017-01-10 Life Technologies Corporation Nucleic acid adaptors and uses thereof
CN102016068A (zh) 2008-01-09 2011-04-13 生命科技公司 制备用于核酸测序的配对标签文库的方法
US8202691B2 (en) 2008-01-25 2012-06-19 Illumina, Inc. Uniform fragmentation of DNA using binding proteins
US8263367B2 (en) 2008-01-25 2012-09-11 Agency For Science, Technology And Research Nucleic acid interaction analysis
US9074244B2 (en) 2008-03-11 2015-07-07 Affymetrix, Inc. Array-based translocation and rearrangement assays
EP2340314B8 (en) 2008-10-22 2015-02-18 Illumina, Inc. Preservation of information related to genomic dna methylation
US8993230B2 (en) * 2008-12-04 2015-03-31 Pacific Biosciences of Californ, Inc. Asynchronous sequencing of biological polymers
US9309557B2 (en) 2010-12-17 2016-04-12 Life Technologies Corporation Nucleic acid amplification
US9334531B2 (en) 2010-12-17 2016-05-10 Life Technologies Corporation Nucleic acid amplification
US10036063B2 (en) 2009-07-24 2018-07-31 Illumina, Inc. Method for sequencing a polynucleotide template
HUE030765T2 (en) 2009-08-25 2017-05-29 Illumina Inc A method for selecting and amplifying polynucleotides
WO2011032040A1 (en) 2009-09-10 2011-03-17 Centrillion Technology Holding Corporation Methods of targeted sequencing
US10174368B2 (en) 2009-09-10 2019-01-08 Centrillion Technology Holdings Corporation Methods and systems for sequencing long nucleic acids
US20120202704A1 (en) 2009-12-07 2012-08-09 Illumina, Inc. Multi-sample indexing for multiplex genotyping
EP2390350A1 (en) * 2010-05-27 2011-11-30 Centre National de la Recherche Scientifique (CNRS) Method of DNA sequencing by polymerisation
US9029103B2 (en) 2010-08-27 2015-05-12 Illumina Cambridge Limited Methods for sequencing polynucleotides
US8483969B2 (en) 2010-09-17 2013-07-09 Illuminia, Inc. Variation analysis for multiple templates on a solid support
WO2012050920A1 (en) 2010-09-29 2012-04-19 Illumina, Inc. Compositions and methods for sequencing nucleic acids
EP2652148B1 (en) 2010-12-17 2016-11-30 Life Technologies Corporation Methods, compositions, systems, apparatuses and kits for nucleic acid amplification
US20120252682A1 (en) * 2011-04-01 2012-10-04 Maples Corporate Services Limited Methods and systems for sequencing nucleic acids
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
US9092401B2 (en) 2012-10-31 2015-07-28 Counsyl, Inc. System and methods for detecting genetic variation
WO2014031163A1 (en) * 2012-08-24 2014-02-27 Life Technologies Corporation Methods, compositions, systems, apparatuses and kits for nucleic acid paired end sequencing
US9181583B2 (en) 2012-10-23 2015-11-10 Illumina, Inc. HLA typing using selective amplification and sequencing
ES2732012T3 (es) * 2013-03-14 2019-11-20 Abbott Molecular Inc Minimización de errores utilizando uracil-ADN-N-glicosilasa
US9255265B2 (en) 2013-03-15 2016-02-09 Illumina, Inc. Methods for producing stranded cDNA libraries
US9822408B2 (en) * 2013-03-15 2017-11-21 Nugen Technologies, Inc. Sequential sequencing
AU2014284584B2 (en) 2013-07-01 2019-08-01 Illumina, Inc. Catalyst-free surface functionalization and polymer grafting
ES2628485T3 (es) 2013-07-03 2017-08-03 Illumina, Inc. Secuenciación mediante síntesis ortogonal
EP3227461A1 (en) 2014-12-05 2017-10-11 Amyris, Inc. High-throughput sequencing of polynucleotides
EP3303614B1 (en) 2015-05-29 2020-03-11 Illumina Cambridge Limited Enhanced utilization of surface primers in clusters
EP3329007B1 (en) 2015-07-30 2021-02-24 Illumina, Inc. Orthogonal deblocking of nucleotides
CN106434856B (zh) * 2015-08-06 2020-02-07 深圳华大智造科技有限公司 一种测序仪运行测试的方法
US10781481B2 (en) 2016-04-27 2020-09-22 Bio-Rad Laboratories, Inc. miRNA transcriptome methods and compositions
EP3449011B1 (en) * 2016-04-29 2020-11-04 Omniome, Inc. Method of nucleic acid sequence determination
US10597643B2 (en) 2016-04-29 2020-03-24 Omniome, Inc. Polymerases engineered to reduce nucleotide-independent DNA binding
US10443098B2 (en) 2016-08-15 2019-10-15 Omniome, Inc. Method and system for sequencing nucleic acids
CN110168105A (zh) * 2016-12-09 2019-08-23 瑞泽恩制药公司 用于对t细胞受体进行测序的系统和方法及其用途
US20210072255A1 (en) 2016-12-16 2021-03-11 The Brigham And Women's Hospital, Inc. System and method for protein corona sensor array for early detection of diseases
WO2018132389A1 (en) * 2017-01-10 2018-07-19 Omniome, Inc. Polymerases engineered to reduce nucleotide-independent dna binding
US10415029B2 (en) 2017-01-20 2019-09-17 Omniome, Inc. Allele-specific capture of nucleic acids
US9932631B1 (en) 2017-09-11 2018-04-03 Omniome, Inc. Genotyping by polymerase binding
WO2018136118A1 (en) * 2017-01-20 2018-07-26 Omniome, Inc. Genotyping by polymerase binding
US10161003B2 (en) 2017-04-25 2018-12-25 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
US9951385B1 (en) 2017-04-25 2018-04-24 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
CN113412274A (zh) 2018-11-07 2021-09-17 禧尔公司 用于蛋白质冠分析的组合物、方法和系统及其用途
CA3103736A1 (en) 2018-12-05 2020-06-11 Illumina Cambridge Limited Methods and compositions for cluster generation by bridge amplification
CN112739830A (zh) 2018-12-18 2021-04-30 伊卢米纳剑桥有限公司 使用单一表面引物进行配对末端测序的方法和组合物
US20200318174A1 (en) 2019-04-03 2020-10-08 Agilent Technologies, Inc. Compositions and methods for identifying and characterizing gene translocations, rearrangements and inversions
KR20220032516A (ko) 2019-05-03 2022-03-15 울티마 제노믹스, 인크. 합성 방법에 의한 고속-정방향 시퀀싱
WO2020227382A1 (en) * 2019-05-08 2020-11-12 Qiagen Sciences, Llc Sequential sequencing methods and compositions
CN117169534A (zh) 2019-08-05 2023-12-05 禧尔公司 用于样品制备、数据生成和蛋白质冠分析的系统和方法
TW202120693A (zh) * 2019-08-21 2021-06-01 美商伊路米納有限公司 偵測核苷酸之聚合酶併入的方法
WO2021178467A1 (en) 2020-03-03 2021-09-10 Omniome, Inc. Methods and compositions for sequencing double stranded nucleic acids
ES2965266T3 (es) 2020-03-09 2024-04-11 Illumina Inc Métodos para la secuenciación de polinucleótidos
IL300826A (en) 2020-08-25 2023-04-01 Seer Inc Compositions and methods for testing proteins and nucleic acids
US20240043918A1 (en) * 2020-11-04 2024-02-08 Ultima Genomics, Inc. Methods and systems for determinng sequencing read distances
US11859241B2 (en) 2021-06-17 2024-01-02 Element Biosciences, Inc. Compositions and methods for pairwise sequencing
US11236388B1 (en) 2021-06-17 2022-02-01 Element Biosciences, Inc. Compositions and methods for pairwise sequencing
AU2022409487A1 (en) 2021-12-16 2024-01-18 Illumina, Inc. Hybrid clustering
AU2022413263A1 (en) 2021-12-17 2024-01-18 Illumina, Inc. Orthogonal hybridization
EP4341425A2 (en) 2022-03-15 2024-03-27 Illumina, Inc. Concurrent sequencing of forward and reverse complement strands on concatenated polynucleotides for methylation detection
WO2023175041A1 (en) 2022-03-15 2023-09-21 Illumina, Inc. Concurrent sequencing of forward and reverse complement strands on concatenated polynucleotides
WO2024057280A1 (en) 2022-09-16 2024-03-21 Illumina Cambridge Limited Nanoparticle with polynucleotide binding site and method of making thereof
WO2024061799A1 (en) 2022-09-19 2024-03-28 Illumina, Inc. Deformable polymers comprising immobilised primers
US20240102067A1 (en) 2022-09-26 2024-03-28 Illumina, Inc. Resynthesis Kits and Methods
US20240124929A1 (en) 2022-09-30 2024-04-18 Illumina, Inc. Mesophilic compositions for nucleic acid amplification
US20240110221A1 (en) 2022-09-30 2024-04-04 Illumina, Inc. Methods of modulating clustering kinetics
US20240110234A1 (en) 2022-09-30 2024-04-04 Illumina, Inc. Amplification Compositions and Methods
US20240124914A1 (en) 2022-09-30 2024-04-18 Illumina, Inc. Thermophilic compositions for nucleic acid amplification

Family Cites Families (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB205153A (en) 1922-07-04 1923-10-04 Charles Ashton Henry Bullock Improvements in type setting apparatus
US4292503A (en) 1979-05-14 1981-09-29 Emerson Electric Co. Split-band electric heater
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
EP0224126A3 (en) 1985-11-25 1989-02-01 The University of Calgary Covalently linked complementary oligodeoxynucleotides as universal nucleic acid sequencing primer linkers
US6270961B1 (en) 1987-04-01 2001-08-07 Hyseq, Inc. Methods and apparatus for DNA sequencing and DNA identification
WO1989001050A1 (en) 1987-07-31 1989-02-09 The Board Of Trustees Of The Leland Stanford Junior University Selective amplification of target polynucleotide sequences
SE8801070D0 (sv) 1988-03-23 1988-03-23 Pharmacia Ab Method for immobilizing a dna sequence on a solid support
US6107023A (en) 1988-06-17 2000-08-22 Genelabs Technologies, Inc. DNA amplification and subtraction techniques
GB8818020D0 (en) 1988-07-28 1988-09-01 Ici Plc Method for amplification of nucleotide sequences
US5512439A (en) 1988-11-21 1996-04-30 Dynal As Oligonucleotide-linked magnetic particles and uses thereof
CA2004326A1 (en) 1988-12-23 1990-06-23 Nanibushan Dattagupta Assay of sequences using amplified genes
US5629158A (en) 1989-03-22 1997-05-13 Cemu Bitecknik Ab Solid phase diagnosis of medical conditions
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5547839A (en) 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US5302509A (en) 1989-08-14 1994-04-12 Beckman Instruments, Inc. Method for sequencing polynucleotides
JP3096722B2 (ja) 1990-01-17 2000-10-10 日本ケミカルリサーチ株式会社 ポリメラーゼ・チェーン・リアクション用プライマーの作製法およびそれを用いるｄｎａの増幅法
US5118604A (en) 1990-06-15 1992-06-02 Yale University Restriction-fragment DNA probes and probe clusters
WO1993004199A2 (en) 1991-08-20 1993-03-04 Scientific Generics Limited Methods of detecting or quantitating nucleic acids and of producing labelled immobilised nucleic acids
HU223760B1 (hu) 1991-09-24 2005-01-28 Keygene N.V. Szelektív restrikciós fragmentumsokszorosítás, általános módszer DNS-fingerprint analízisére
AU3728093A (en) 1992-02-19 1993-09-13 Public Health Research Institute Of The City Of New York, Inc., The Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
EP0656068B1 (en) 1992-07-24 1999-12-15 University Of South Australia Amplification and detection process
RU2048522C1 (ru) 1992-10-14 1995-11-20 Институт белка РАН Способ размножения нуклеиновых кислот, способ их экспрессии и среда для их осуществления
JPH07203998A (ja) 1994-01-26 1995-08-08 Hamamatsu Photonics Kk 核酸塩基配列決定方法
JPH10500862A (ja) 1994-05-28 1998-01-27 テプネル・メディカル・リミテッド 核酸のコピーの産生
US6090592A (en) 1994-08-03 2000-07-18 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid on supports
US5641658A (en) 1994-08-03 1997-06-24 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid with two primers bound to a single solid support
US6060288A (en) 1994-08-03 2000-05-09 Mosaic Technologies Method for performing amplification of nucleic acid on supports
CA2218188A1 (en) 1995-04-11 1996-10-17 Trustees Of Boston University Solid phase sequencing of biopolymers
DE19515552A1 (de) * 1995-04-27 1996-10-31 Europ Lab Molekularbiolog Simultane Sequenzierung von Nukleinsäuren
SE9504099D0 (sv) 1995-11-16 1995-11-16 Pharmacia Biotech Ab A method of sequencing
AU733782B2 (en) * 1996-06-06 2001-05-24 Lynx Therapeutics, Inc. Sequencing by ligation of encoded adaptors
US5935788A (en) 1996-06-25 1999-08-10 Lifespan Biosciences, Inc. Subtractive hybridization techniques for identifying differentially expressed and commonly expressed nucleic acid
US5837466A (en) 1996-12-16 1998-11-17 Vysis, Inc. Devices and methods for detecting nucleic acid analytes in samples
US20020061532A1 (en) 1997-02-14 2002-05-23 Mosaic Technologies, Inc. Method and apparatus for performing amplification of nucleic acids on supports
JP2001517948A (ja) 1997-04-01 2001-10-09 グラクソ、グループ、リミテッド 核酸配列決定法
EP1591541B1 (en) 1997-04-01 2012-02-15 Illumina Cambridge Limited Method of nucleic acid sequencing
US6326489B1 (en) 1997-08-05 2001-12-04 Howard Hughes Medical Institute Surface-bound, bimolecular, double-stranded DNA arrays
US6087099A (en) 1997-09-08 2000-07-11 Myriad Genetics, Inc. Method for sequencing both strands of a double stranded DNA in a single sequencing reaction
US6511803B1 (en) 1997-10-10 2003-01-28 President And Fellows Of Harvard College Replica amplification of nucleic acid arrays
US20030022207A1 (en) 1998-10-16 2003-01-30 Solexa, Ltd. Arrayed polynucleotides and their use in genome analysis
AR021833A1 (es) 1998-09-30 2002-08-07 Applied Research Systems Metodos de amplificacion y secuenciacion de acido nucleico
WO2000024939A1 (en) 1998-10-27 2000-05-04 Affymetrix, Inc. Complexity management and analysis of genomic dna
US20030108867A1 (en) 1999-04-20 2003-06-12 Chee Mark S Nucleic acid sequencing using microsphere arrays
US6521428B1 (en) 1999-04-21 2003-02-18 Genome Technologies, Llc Shot-gun sequencing and amplification without cloning
US6300070B1 (en) 1999-06-04 2001-10-09 Mosaic Technologies, Inc. Solid phase methods for amplifying multiple nucleic acids
US6339147B1 (en) * 1999-07-29 2002-01-15 Epoch Biosciences, Inc. Attachment of oligonucleotides to solid supports through Schiff base type linkages for capture and detection of nucleic acids
DE10051564A1 (de) 2000-10-18 2002-08-01 Axaron Bioscience Ag Neue Verfahren zur parallelen Sequenzierung eines Nukleinsäuregemisches an einer Oberfläche
DE60025850T2 (de) 1999-12-29 2006-08-03 Keygene N.V. Verfahren zur erzeugung von oligonukleotiden, im besonderen zur detektion amplifizierter restriktionsfragmente, die durch aflp erhalten wurden
WO2001079553A1 (en) 2000-04-14 2001-10-25 Lynx Therapeutics, Inc. Method and compositions for ordering restriction fragments
AR031640A1 (es) 2000-12-08 2003-09-24 Applied Research Systems Amplificacion isotermica de acidos nucleicos en un soporte solido
EP1256632A3 (en) 2001-05-07 2004-01-02 Smithkline Beecham Corporation High throughput polymorphism screening
GB0112238D0 (en) * 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
EP1472335A4 (en) 2001-11-08 2005-12-28 Univ Johns Hopkins METHOD AND SYSTEMS FOR NUCLEIC ACID SEQUENCING
WO2003074734A2 (en) 2002-03-05 2003-09-12 Solexa Ltd. Methods for detecting genome-wide sequence variations associated with a phenotype
US20040002090A1 (en) 2002-03-05 2004-01-01 Pascal Mayer Methods for detecting genome-wide sequence variations associated with a phenotype
GB0205153D0 (en) 2002-03-05 2002-04-17 Manteia S A Methods for detecting genome-wide sequence variations associated with a phenotype
US20040126765A1 (en) 2002-12-27 2004-07-01 Adams Craig W. Method and compositions for sequencing nucleic acid molecules
WO2004070007A2 (en) 2003-01-29 2004-08-19 454 Corporation Method for preparing single-stranded dna libraries
CA2515938A1 (en) 2003-02-12 2004-08-26 Genizon Svenska Ab Methods and means for nucleic acid sequencing
JP4691014B2 (ja) 2003-02-26 2011-06-01 カリダ ゲノミクス，インコーポレーテッド ハイブリダイゼーションによるランダムアレイｄｎａ分析
GB0324456D0 (en) 2003-10-20 2003-11-19 Isis Innovation Parallel DNA sequencing methods
ATE510024T1 (de) 2003-10-31 2011-06-15 Advanced Genetic Analysis Corp Ab Verfahren zur herstellung eines gepaarten tag aus einer nukleinsäuresequenz sowie verfahren zur verwendung davon
GB0400584D0 (en) 2004-01-12 2004-02-11 Solexa Ltd Nucleic acid chacterisation
CN1950519A (zh) 2004-02-27 2007-04-18 哈佛大学的校长及成员们 聚合酶群落荧光原位测序珠子
WO2005089110A2 (en) 2004-02-27 2005-09-29 President And Fellows Of Harvard College Polynucleotide synthesis
GB2412170A (en) 2004-03-16 2005-09-21 Plant Bioscience Ltd A method for enriching for target nucleic acids in a sample
GB2413796B (en) 2004-03-25 2006-03-29 Global Genomics Ab Methods and means for nucleic acid sequencing
WO2006073504A2 (en) 2004-08-04 2006-07-13 President And Fellows Of Harvard College Wobble sequencing
US20060078899A1 (en) 2004-10-12 2006-04-13 Scheffer Alicia F Methods and compositions for reducing label variation in array-based comparative genome hybridization assays
JP2008538496A (ja) 2005-04-12 2008-10-30 ４５４ ライフ サイエンシーズ コーポレイション ウルトラディープ配列決定を用いて配列変異体を決定するための方法
US7601499B2 (en) 2005-06-06 2009-10-13 454 Life Sciences Corporation Paired end sequencing
US8428882B2 (en) 2005-06-14 2013-04-23 Agency For Science, Technology And Research Method of processing and/or genome mapping of diTag sequences
GB0514935D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Methods for sequencing a polynucleotide template
GB0514910D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Method for sequencing a polynucleotide template
GB0514936D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Preparation of templates for nucleic acid sequencing
US7960104B2 (en) 2005-10-07 2011-06-14 Callida Genomics, Inc. Self-assembled single molecule arrays and uses thereof
GB0522310D0 (en) 2005-11-01 2005-12-07 Solexa Ltd Methods of preparing libraries of template polynucleotides
EP1969146B1 (en) 2006-01-04 2010-10-06 Si Lok Methods for nucleic acid mapping and identification of fine-structural-variations in nucleic acids and utilities
WO2007091077A1 (en) 2006-02-08 2007-08-16 Solexa Limited Method for sequencing a polynucleotide template
US20080009420A1 (en) 2006-03-17 2008-01-10 Schroth Gary P Isothermal methods for creating clonal single molecule arrays
US20070231823A1 (en) 2006-03-23 2007-10-04 Mckernan Kevin J Directed enrichment of genomic DNA for high-throughput sequencing
WO2008002502A2 (en) 2006-06-23 2008-01-03 Illumina, Inc. Devices and systems for creation of dna cluster arrays
US7754429B2 (en) * 2006-10-06 2010-07-13 Illumina Cambridge Limited Method for pair-wise sequencing a plurity of target polynucleotides
US7910354B2 (en) 2006-10-27 2011-03-22 Complete Genomics, Inc. Efficient arrays of amplified polynucleotides
EP2121983A2 (en) * 2007-02-02 2009-11-25 Illumina Cambridge Limited Methods for indexing samples and sequencing multiple nucleotide templates
US20090093378A1 (en) 2007-08-29 2009-04-09 Helen Bignell Method for sequencing a polynucleotide template

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Publication number Publication date
CN101415839B (zh) 2012-06-27
WO2007091077A1 (en) 2007-08-16
DK1987159T3 (da) 2012-12-10
US20130165327A1 (en) 2013-06-27
EP1987159A1 (en) 2008-11-05
EP1987159B2 (en) 2020-08-12
US9994896B2 (en) 2018-06-12
CA2641851A1 (en) 2007-08-16
CN101415839A (zh) 2009-04-22
US10876158B2 (en) 2020-12-29
US20150203910A1 (en) 2015-07-23
US8945835B2 (en) 2015-02-03
EP1987159B1 (en) 2012-09-12
US20180363047A1 (en) 2018-12-20
US8192930B2 (en) 2012-06-05
US20110009276A1 (en) 2011-01-13
SG169356A1 (en) 2011-03-30

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